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Displaying drugs 501 - 525 of 1097 in total
Trofinetide is a novel synthetic analog of glypromate, also known as glycine–proline–glutamate (GPE), a naturally occurring protein in the brain and the N-terminal tripeptide of insulin-like growth factor 1 (IGF-1). Trofinetide was approved by the FDA on March 10, 2023, for the treatment of Rett syndrome,[L45718,L45748] which is an X-linked...
Approved
Investigational
Matched Synonyms: … glycyl-L-2-methylprolyl-L-glutamic acid …
Matched Description: … ), a naturally occurring protein in the brain and the N-terminal tripeptide of insulin-like growth factor ... [A258438] Trofinetide is believed to work by reducing inflammation and apoptosis of neurons. ... L45748] which is an X-linked neurodevelopmental disorder characterized by a range of cognitive, motor, and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Synonyms: … Amylin human ... Human amylin ... Islet amyloid polypeptide (human) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Chiglitazar is under investigation in clinical trial NCT06125587 (Chiglitazar/metformin in Non-obese Women With PCOS).
Investigational
Matched Synonyms: … O-(2-(9h-carbazol-9-yl)ethyl)-n-(2-(4-fluorobenzoyl)phenyl)-l-tyrosine ... L-tyrosine, o-(2-(9h-carbazol-9-yl)ethyl)-n-(2-(4-fluorobenzoyl)phenyl)- …
Experimental
Matched Name: … 3-Amino-6-Hydroxy-Tyrosine
Experimental
Matched Name: … N,O-didansyl-L-tyrosine
Matched Categories: … Amino Acids, Peptides, and Proteins …
Neuren Pharmaceuticals was developing Glypromate (glycine-proline glutamate), a naturally occurring small-molecule neuroprotectant derived from IGF-1 which inhibits caspase III dependent apoptosis, for the potential treatment of neurodegenerative diseases by IV infusion. In December 2008, the company discontinued further development of the drug after it failed to show an observable effect.
Investigational
Matched Synonyms: … Glycyl-prolyl-glutamic acid …
Matched Description: … Neuren Pharmaceuticals was developing Glypromate (glycine-proline glutamate), a naturally occurring small-molecule …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Anthrax immune globulin is a human antibody given with antibiotics for the treatment of anthrax. It is derived from the plasma of humans immunized with BioThrax (adsorbed anthrax vaccine), which is then further purified. Available as the product Anthrasil (FDA), the result is a solution for slow IV infusion containing...
Approved
Matched Synonyms: … Anthrax immune globulin human ... Anthrax immune globulin (human) ... Anthrax immunoglobulin (human) …
Matched Name: … Anthrax immune globulin human
Matched Description: … polyclonal antibodies that bind the protective antigen (PA) component of Bacillus anthracis lethal and ... to have direct antibacterial activity against anthrax bacteria, which otherwise may continue to grow and ... Anthrax immune globulin is a human antibody given with antibiotics for the treatment of anthrax. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Human Immunoglobulin …
Corticotropin-releasing factor is studied in the treatment of brain cancer. It is made naturally by the hypothalamus (a part of the brain) and can also be made in the laboratory. Human corticotropin-releasing factor may help reduce symptoms caused by edema (swelling) of the brain. It is a type of neurohormone,...
Investigational
Matched Synonyms: … Corticoliberin human ... Corticorelin (human) ... Human corticoliberin …
Matched Description: … It is made naturally by the hypothalamus (a part of the brain) and can also be made in the laboratory ... Human corticotropin-releasing factor may help reduce symptoms caused by edema (swelling) of the brain …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Investigational
Matched Synonyms: … L-lysinamide, l-histidyl-d-tryptophyl-l-alanyl-l-tryptophyl-d-phenylalanyl- …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … Glycine, L-prolyl-L-prolyl-L-leucyl-L-seryl-L-glutaminyl-L-alpha-glutamyl-L-threonyl-Lphenylalanyl- L-seryl-L-alpha-aspartyl-L-leucyl-L-tryptophyl-L-lysyl-L-leucyl-L-leucyl-L-lysyl-Llysyl ... - L-tryptophyl-L-lysyl-L-methionyl-L-arginyl-L-arginyl-L-asparaginy …
Investigational
Matched Synonyms: … L-tyrosine, o-((5-amino-2-phenyl-7-benzoxazolyl)methyl)-3,5-dichloro- ... O-((5-amino-2-phenyl-1,3-benzoxazol-7-yl)methyl)-3,5- dichloro-l-tyrosine
Matched Categories: … Amino Acids, Peptides, and Proteins …
A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985)....
Approved
Investigational
Matched International brands: … Carustine
Matched Description: … It is used in the treatment of brain tumors and various other malignant neoplasms. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Approved
Experimental
Matched Synonyms: … Albumin human, microspheres ... Albumin microsphere human serum ... Albumin, microsphere human serum …
Matched Name: … Human albumin microspheres …
Human interleukin-2 is under investigation in clinical trial NCT03475134 (TIL-ACT After NMA Chemo With IL-2 and Nivo Rescue in mMEL).
Investigational
Matched Name: … Human interleukin-2 …
Matched Description: … IL-2 and Nivo Rescue in mMEL). ... Human interleukin-2 is under investigation in clinical trial NCT03475134 (TIL-ACT After NMA Chemo With …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Human amniotic fluid is the liquid surrounding the human embryo and fetus. Physically, the fluid provides protection through cushioning. Chemically, the fluid provides protection through its inherent antibacterial properties. The fluid contains carbohydrates, proteins, lipids, electrolytes, urea, immunoglobulins, growth factors, and vitamins.[L16373,L16378]
Investigational
Matched Name: … Human Amniotic Fluid …
Matched Description: … Human amniotic fluid is the liquid surrounding the human embryo and fetus. ... fluid contains carbohydrates, proteins, lipids, electrolytes, urea, immunoglobulins, growth factors, and
Recombinant human thrombopoietin is a full-length glycosylated cytokine produced by Chinese hamster ovary cells and is used to promote the generation of megakaryocytes and platelets.[A225691, A225696] This drug is used in the treatment of thrombocytopenia.
Investigational
Matched Name: … Recombinant Human Thrombopoietin …
Matched Description: … cells and is used to promote the generation of megakaryocytes and platelets. ... Recombinant human thrombopoietin is a full-length glycosylated cytokine produced by Chinese hamster ovary …
Investigational
Matched Synonyms: … Laminin-111 (Human) …
Matched Name: … Human Laminin-111 …
Interleukin-8 is under investigation in clinical trial NCT05148234 (BMS-986253 in Myelodysplastic Syndromes).
Investigational
Matched Synonyms: … INTERLEUKIN 8 (HUMAN) …
Matched Name: … Human Interleukin 8 …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Tetanus Immune Globulin is manufactured from human plasma [FDA Label]. It contains antibodies against tetanus toxoid and is primarily used as prophylaxis against tetanus in wounded patients.
Approved
Matched Synonyms: … Tetanus immune globulin human ... Tetanus immune globulin,human ... Tetanus immunoglobulin (human) …
Matched Name: … Tetanus immune globulin, human
Matched Description: … It contains antibodies against tetanus toxoid and is primarily used as prophylaxis against tetanus in ... Tetanus Immune Globulin is manufactured from human plasma [FDA Label]. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins ... Human Tetanus Immune Globulins …
Matched Products: … GAMMAGLOBULINA HUMANA ANTITETÁNICA PASTEURIZADAGRIFOLS250 U.I. …
Experimental
Matched Synonyms: … Human EGF ... Human urogastrone ... Epidermal growth factor (human) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Recombinant human relaxin is a hormone produced during pregnancy that facilitates the birth process by causing a softening and lengthening of the cervix and the pubic symphysis (the place where the pubic bones come together).It is a heterodimer protein secreted by the corpus luteum and placenta during pregnancy.
Investigational
Matched Synonyms: … Human relaxin recombinant ... Recombinant human relaxin ... Human relaxin 2 (relaxin h2) …
Matched Description: … causing a softening and lengthening of the cervix and the pubic symphysis (the place where the pubic ... bones come together).It is a heterodimer protein secreted by the corpus luteum and placenta during pregnancy ... Recombinant human relaxin is a hormone produced during pregnancy that facilitates the birth process by …
Edodekin alfa is under investigation in clinical trial NCT01468896 (Cetuximab and Recombinant Interleukin-12 in Treating Patients With Squamous Cell Carcinoma of the Head and Neck That Is Recurrent, Metastatic, or Cannot Be Removed by Surgery).
Investigational
Matched Synonyms: … Interleukin-12, human ... Interleukin 12 (human) ... Human il-12 (recombinant) …
Matched Description: … Edodekin alfa is under investigation in clinical trial NCT01468896 (Cetuximab and Recombinant Interleukin ... -12 in Treating Patients With Squamous Cell Carcinoma of the Head and Neck That Is Recurrent, Metastatic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Kisspeptin-10 is under investigation in clinical trial NCT03771326 (KP-10 and Insulin Secretion in Men).
Investigational
Matched Synonyms: … Human metastin 45-54 ... Kisspeptin-10 (human) …
Matched Description: … Kisspeptin-10 is under investigation in clinical trial NCT03771326 (KP-10 and Insulin Secretion in Men …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and also inhibits several other enzymes. It is a member of the serpin superfamily.
Approved
Matched Synonyms: … Antithrombin III (human) ... Antithrombin III human ... Antithrombin III,human
Matched Name: … Antithrombin III human
Matched Description: … A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Investigational
Matched Synonyms: … Porphobilinogen deaminase, human recombinant ... Recombinant human porphobilinogen deaminase ... Hydroxymethylbilane synthase, recombinant human erythyroid isoform …
Matched Name: … Porphobilinogen deaminase, human recombinant …
Displaying drugs 501 - 525 of 1097 in total