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Displaying drugs 501 - 525 of 1131 in total
The trefoil factor 2 (TFF2) peptide is a low-molecular weight protein and one of the three trefoil-motif-containing proteins. They are expressed predominantly in gastric tissues with the source for them being predominantly stromal cells, although expression of TFF2 mRNA transcripts also occurs with tissue macrophages. The peptides themselves are most...
Investigational
Matched Name: … Trefoil Factor 2 …
Matched Description: … The trefoil factor 2 (TFF2) peptide is a low-molecular weight protein and one of the three trefoil-motif-containing …
Matched Categories: … Trefoil Factors
MDX-018, also known as HuMax-Inflam, is a fully human antibody that is directed to IL-8 (interleukin-8) and may have potential application in oncology and inflammation. Trials will initially focus on studies to treat glioblastoma, a cancer of the central nervous system. Other possible indications include chronic obstructive pulmonary disease (COPD)...
Investigational
Matched International brands: … HuMax-Inflam …
Matched Description: … In pre-clinical studies, HuMax-Inflam has been shown to inhibit tumor growth in tumor models using primary ... 8) and may have potential application in oncology and inflammation. ... Other possible indications include chronic obstructive pulmonary disease (COPD) and pustular dermatoses …
Cerliponase alfa is an enzyme replacement treatment for a specific form of Batten disease. It was the first FDA-approved treatment to slow loss of walking ability (ambulation) in symptomatic pediatric patients 3 years of age and older with late infantile neuronal ceroid lipofuscinosis type 2 (CLN2), also known as tripeptidyl...
Approved
Investigational
Matched Synonyms: … Immature human tripeptidyl-peptidase 1 ... Immature cell growth-inhibiting gene 1 protein …
Matched Description: … treatment to slow loss of walking ability (ambulation) in symptomatic pediatric patients 3 years of age and
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
RR001 is an investigational gene therapy consisting of autologous human adipose perivascular stromal cells genetically modified to secrete soluble tumour necrosis factor-related apoptosis-inducing ligand (AD-PC sTRAIL).
Investigational
Matched Synonyms: … factor-related apoptosis-inducing ligand ... autologous human adipose perivascular stromal cells genetically modified to secrete soluble tumour necrosis …
Matched Description: … RR001 is an investigational gene therapy consisting of autologous human adipose perivascular stromal ... cells genetically modified to secrete soluble tumour necrosis factor-related apoptosis-inducing ligand …
Giroctocogene fitelparvovec is under investigation in clinical trial NCT04370054 (Study to Evaluate the Efficacy and Safety of PF-07055480 in Moderately Severe to Severe Hemophilia a Adults).
Investigational
Matched Synonyms: … factor viii-specifying) ... Dna (recombinant adeno-associated virus 6 vector pf-07055480 human b-domain-deleted blood-coagulation ... Aav2/6-b-domain-deleted blood coagulation factor viii …
Matched Description: … fitelparvovec is under investigation in clinical trial NCT04370054 (Study to Evaluate the Efficacy and
Human secretin is a gastrointestinal peptide hormone that regulates secretions in the stomach, pancreas, and liver. The hormone is produced from the enterochromaffin cells in the duodenum in response to the duodenal content with the pH less than 4.5 . The main action of secretin is to stimulate the pancreas...
Approved
Matched Synonyms: … Human secretin ... Secretin human ... Secretin (human) …
Matched Name: … Secretin human
Matched Description: … Synthetic human secretin displays equivalent biological activity and properties as naturally-occurring ... , and liver. ... of pancreatic exocrine dysfunction and the diagnosis of gastrinoma, and facilitate the identification …
Matched Salts name: … Secretin human pentahydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Experimental
Matched Synonyms: … Palmityl palmitate …
Alfimeprase is a recombinant analog of fibrolase. Fibrolase is a zinc-containing metalloproteinase isolated from the venom of the southern copperhead snake (Agkistrodon contortrix contortrix). It is a small protein that contains 203 residues (Randolph et al. 1992). Alfimeprase is being developed by Nuvelo.
Investigational
Matched Synonyms: … 3-203-FIBROLASE (3-SERINE) (AGKISTRODON CONTORTRIX CONTORTRIX RECOMBINANT) …
Matched Description: … Alfimeprase is a recombinant analog of fibrolase. ... Fibrolase is a zinc-containing metalloproteinase isolated from the venom of the southern copperhead snake …
Matched Categories: … Enzymes and Coenzymes …
An oligosaccharide antibiotic produced by various streptomyces. [PubChem]
Approved
Investigational
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Humatin ... HUMATIN ... Humatin - Pulvis …
Investigational
Matched Synonyms: … Immunoglobulin G4 [230-proline,237-glutamic acid], anti-(human tumor necrosis factor superfamily protein ... TNFSF14) (human-Mus musculus monoclonal SAR252067 γ4-chain), disulfide with human-Mus musculus monoclonal …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Zanolimumab is a fully human monoclonal antibody directed against CD4.
Investigational
Matched Synonyms: … Humax-cd4 ... IMMUNOGLOBULIN, ANTI-(HUMAN CD4 ANTIGEN) (HUMAN MONOCLONAL 6G5 HEAVY CHAIN), DISULPHIDE WITH HUMAN MONOCLONAL …
Matched Description: … Zanolimumab is a fully human monoclonal antibody directed against CD4. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Ferric subsulfate is a stypic or hemostatic agent that causes agglutination of surface proteins resulting in local hemostasis. It has the chemical formula Fe4(OH)2(SO4)5. It is used after superficial skin biopsies.
Approved
Experimental
Matched Synonyms: … basic ferric sulfate solution …
MANF is a human recombinant mesencephalic, astrocyte-derived neurotrophic factor.
Investigational
Matched Synonyms: … Mesencephalic astrocyte-derived neurotrophic factor ... Mesencephalic, astrocyte-derived neurotrophic factor
Matched Description: … MANF is a human recombinant mesencephalic, astrocyte-derived neurotrophic factor. …
Calcitonin was first discovered in isolated parathyroid tissue as a substance with a serum-calcium-lowering effect. It is constituted as a 32-amino acid single chain polypeptide structure that gets secreted as a regulatory agent in calcium-phosphorus metabolism. It is used as an alternative for people developing antibodies against salmon calcitonin.
Approved
Investigational
Matched Synonyms: … Calcitonin human ... Calcitonin (human) ... Calcitonin, human
Matched Name: … Human calcitonin …
Matched Categories: … Sex Hormones and Insulins ... calcitonin (human synthetic) …
Investigational
Matched Synonyms: … Proinsulin human ... Proinsulin biosynthetic human ... Proinsulin recombinant human
Matched Name: … Proinsulin human
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Investigational
Matched Synonyms: … Human haptoglobulin …
Matched Name: … Haptoglobulin (human) …
Bismuth subnitrate, also referred to as bismuth oxynitrate or bismuthyl nitrate, is a highly water-soluble crystalline compound that has been used as a treatment for duodenal ulcers and anti-diarrheic agent . The use of bismuth substrate as an active ingredient in over-the-counter antacids is approved by the FDA.
Approved
Matched Synonyms: … Bismuth nitrate, basic
Matched Description: … is a highly water-soluble crystalline compound that has been used as a treatment for duodenal ulcers and
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
Corticorelin, available commercially as corticorelin ovine triflutate (tradename Acthrel), is a synthetic form of the peptide human corticotropin-releasing hormone (hCRH), a potent stimulator of adrenocorticotropic hormone (ACTH) release from the anterior pituitary. Endogenous forms hCRH are involved in the stress response and its main function is stimulation of the pituitary...
Approved
Matched Synonyms: … Ovine ACTH releasing factor ... Ovine corticotropin-releasing factor ... Corticotropin-releasing factor (sheep) …
Matched Description: … Endogenous forms hCRH are involved in the stress response and its main function is stimulation of the ... If corticorelin injection results in an increase of plasma ACTH and cortisol, the patient is diagnosed ... However, if corticorelin injection does not result in an increase of plasma ACTH and cortisol, the patient …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Valoctocogene roxaparvovec is an adeno-associated virus serotype 5 (AAV5) based gene therapy vector that expresses the B-domain deleted SQ form of human coagulation factor VIII (hFVIII-SQ). The expression of hFVIII-SQ is driven by a liver-specific promoter, which enables hepatocytes to produce factor VIII protein and increase the levels of active...
Approved
Investigational
Matched Synonyms: … DNA (synthetic adeno-associated virus 5 vector BMN 270 human blood-coagulation factor VIII SQ variant-specifying …
Matched Description: … VIII protein and increase the levels of active factor VIII in blood. ... expresses the B-domain deleted SQ form of human coagulation factor VIII (hFVIII-SQ). ... [L43282,A252807] Valoctocogene roxaparvovec was approved by EMA in September 2022 and is indicated for …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Cellular and Gene Therapy ... Biological Factors ... Blood Coagulation Factors
One of the components of virginiamycin, a cyclic polypeptide antibiotic complex from streptomyces virginiae, s. Loidensis, s. Mitakaensis, s. Pristina-spiralis, s. Ostreogriseus, and others. It is used to treat infections with gram-positive organisms and as a growth promoter in cattle, swine, and poultry.
Experimental
Matched Synonyms: … Virginiamycin factor S ... Virginiamycin factor S1 …
Matched Description: … It is used to treat infections with gram-positive organisms and as a growth promoter in cattle, swine ... , and poultry. ... Ostreogriseus, and others. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Delpacibart is a humanized, bispecific, bivalent monoclonal antibody against coagulation factor 9.
Investigational
Matched Synonyms: … Immunoglobulin G4 [230-proline,de-449-lysine], anti-(human blood-coagulation factor IX) (human clone ... .229′)-bis(disulfide) with anti-(human bl ... 0365-0001-9985 γ4-chain), disulfide with human clone 0365-0001-9985 κ-chain, (228.fwdarw.226′),(231.fwdarw …
Matched Description: … Delpacibart is a humanized, bispecific, bivalent monoclonal antibody against coagulation factor 9. …
Investigational
Matched Synonyms: … factor receptor TNFRSF9) (human-mus musculus monoclonal lvgn6051 .hamma.1-chain), disulfide with human-mus ... Immunoglobulin G1 (de-236-glycine,267-glutamic acid,de-C-terminal lysine), anti-(human tumor necrosis …
Gemifloxacin is a quinolone antibacterial agent with a broad-spectrum activity that is used in the treatment of acute bacterial exacerbation of chronic bronchitis and mild-to-moderate pneumonia. It is available in oral formulations. Gemifloxacin acts by inhibiting DNA synthesis through the inhibition of both DNA gyrase and topoisomerase IV, which are...
Approved
Investigational
Matched International brands: … Factiv
Matched Description: … broad-spectrum activity that is used in the treatment of acute bacterial exacerbation of chronic bronchitis and ... Gemifloxacin acts by inhibiting DNA synthesis through the inhibition of both DNA gyrase and topoisomerase ... IV, which are essential for bacterial growth. …
Ragifilimab is under investigation in clinical trial NCT04225039 (Anti-gitr/anti-pd1/stereotactic Radiosurgery, in Recurrent Glioblastoma).
Investigational
Matched Synonyms: … Immunoglobulin g1 (de-448-lysine), anti-(human tumor necrosis factor receptor tnfrsf18) (human-mus musculus ... monoclonal incagn01876.gamma.1-chain), disulfide with human-mus musculus monoclonal incagn01876 .kappa …
Trastuzumab duocarmazine is under investigation in clinical trial NCT03262935 (SYD985 vs. Physician's Choice in Participants With Her2-positive Locally Advanced or Metastatic Breast Cancer).
Investigational
Matched Synonyms: … Immunoglobulin g1-kappa, anti-(homo sapiens erbb2 (epidermal growth factor receptor 2, receptor tyrosineprotein …
Matched Categories: … HER2 (Human Epidermal Growth Factor Receptor 2) inhibitors ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Displaying drugs 501 - 525 of 1131 in total