Displaying drugs 501 - 525 of 11951 in total
Emicizumab
Emicizumab is a humanized recombinant monoclonal antibody that mimics the function of the coagulation Factor VIII and it has the capacity to bind simultaneously to activated Factor IX and Factor X. The ability of Emicizumab to bind to all these three different factors allows it to overcome immunogenicity and unstable...
Approved
Investigational
Matched Description: … Emicizumab is a humanized recombinant monoclonal antibody that mimics the function of the coagulation …
Ocriplasmin
Ocriplasmin is a recombinant truncated form of human plasmin with a molecular weight of 27.2 kDa produced by recombinant DNA technology in a Pichia pastoris expression system. Ocriplasmin is a protein made up of 249 amino acids and has two peptide chains. Agent for pharmacologic vitreolysis; thrombolytic agent. FDA approved...
Approved
Matched Description: … Ocriplasmin is a recombinant truncated form of human plasmin with a molecular weight of 27.2 kDa produced ... by recombinant DNA technology in a Pichia pastoris expression system. ... Ocriplasmin is a protein made up of 249 amino acids and has two peptide chains. …
Sodium aurothiomalate
Sodium aurothiomalate is a gold compound that is used for its immunosuppressive anti-rheumatic effects. Gold Sodium Thiomalate is supplied as a solution for intramuscular injection containing 50 mg of Gold Sodium Thiomalate per mL. It is most effective in active progressive rheumatoid arthritis and of little or no value in...
Approved
Investigational
Matched Description: … Sodium aurothiomalate is a gold compound that is used for its immunosuppressive anti-rheumatic effects ... Gold Sodium Thiomalate is supplied as a solution for intramuscular injection containing 50 mg of Gold …
Ethylhexyl methoxycrylene
Ethylhexyl methoxycrylene is a photostabilizer that preserves the effectiveness of UV filters by interacting with both the singlet and triplet states . It returns UV filters to their ground states without absorbing sunlight . It is used as a solvent for crystalline UV filters and is easily emulsified and suitable...
Approved
Experimental
Matched Description: … Ethylhexyl methoxycrylene is a photostabilizer that preserves the effectiveness of UV filters by interacting ... It is used as a solvent for crystalline UV filters and is easily emulsified and suitable for use in various …
Susoctocog alfa
Intravenous susoctocog alfa is a recombinant, B-domain deleted, porcine sequence antihaemophilic factor VIII (FVIII) product that has recently been approved for the treatment of bleeding episodes in adults with acquired haemophilia A (AHA). AHA is a rare bleeding disorder that results in a prolonged clotting time as measured by the...
Approved
Investigational
Matched Description: … Susoctocog alfa is a glycoprotein containing a 90 kDa heavy chain and a 80 kDa light chain with the naturally-occuring ... AHA is a rare bleeding disorder that results in a prolonged clotting time as measured by the activated ... B domain replaced with a twenty-four amino acid linker. …
Chloroquine
Chloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria. It was the drug of choice to treat malaria until the development of newer antimalarials such as pyrimethamine, artemisinin, and mefloquine. Chloroquine and its derivative hydroxychloroquine have since been repurposed for the treatment of a...
Approved
Investigational
Vet approved
Matched Description: … Chloroquine and its derivative [hydroxychloroquine] have since been repurposed for the treatment of a …
Rubidium Rb-82
Rubidium chloride Rb-82 injection is a sterile nonpyrogenic solutions of rubidium Rb 82 chloride. It is indicated for Positron Emission Tomography (PET) imaging of the myocardium under rest or pharmacologic stress conditions to evaluate regional myocardial perfusion in adult patients with suspected or existing coronary artery disease.
Approved
Investigational
Matched Description: … Rubidium chloride Rb-82 injection is a sterile nonpyrogenic solutions of rubidium Rb 82 chloride. …
Chlorphenesin
Approved
Experimental
Amaranthus retroflexus whole
Amaranthus retroflexus whole allergenic extract is used in allergenic testing.
Approved
Peginterferon beta-1a
Multiple Sclerosis (MS) is a chronic and inflammatory autoimmune disease of the central nervous system, disrupting communication between the brain and other parts of the body. Most patients diagnosed with this illness experience their initial disease symptoms between the age of 20 to 40, often the most productive years of...
Approved
Matched Description: … Multiple Sclerosis (MS) is a chronic and inflammatory autoimmune disease of the central nervous system …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Technetium Tc-99m exametazime
Technetium Tc-99m exametazime is a radiopharmaceutical sold under the trade name Ceretec used in the detection of altered regional cerebral perfusion in stroke and other cerebrovascular diseases. It can also be used for the labelling of leukocytes to localise intra-abdominal infections and inflammatory bowel disease. Exametazime, also known as hexamethylpropyleneamine...
Approved
Matched Description: … Technetium Tc-99m exametazime is a radiopharmaceutical sold under the trade name Ceretec used in the ... Exametazime, also known as hexamethylpropyleneamine oxime or HMPAO, acts as a chelating agent for the …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Technetium Tc-99m succimer
Technetium Tc-99m (99mTc) succimer, also known as technetium Tc-99m dimercaptosuccinic acid (DMSA), is a radioactive diagnostic agent used to evaluate functional renal tissue and tubular function in patients with renal parenchymal disorders. It works by binding to the cortical region of the kidneys. Technetium Tc-99m succimer is used with gamma...
Approved
Matched Description: … >99mTc) succimer, also known as technetium Tc-99m dimercaptosuccinic acid (DMSA),[A245643] is a …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Thiosulfuric acid
Thiosulfuric acid is available in its salt forms sodium thiosulfate and sodium thiosulfate pentahydrate. Sodium thiosulfate is part of the World Health Organization’s list of essential medicines, and it has a variety of industrial uses, including food preservative, water de-chlorinator and paper pulp bleaching agent. Sodium thiosulfate is rapidly degraded...
Approved
Investigational
Matched Description: … Sodium thiosulfate is part of the World Health Organization’s list of essential medicines, and it has a ... [L43337] When administered 6 hours after cisplatin chemotherapy, Sodium thiosulfate leads to a lower ... cyanide poisoning[L310,L43332,A252832] and it is frequently used in conjunction with sodium nitrite (a …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Tragacanth
Tragacanth allergenic extract is used in allergenic testing.
Approved
Matched Categories: … Compounds used in a research, industrial, or household setting …
Lactitol
Lactitol, also known as 4-β-D-galactopyranosyl-D-glucitol, is a sugar alcohol synthesized from lactose. It is used in food manufacturing as a nutritive sweetener and is approximately 35% as sweet as table sugar (i.e. sucrose). Clinically, lactitol has been investigated for use as an osmotic laxative and, along with other non-absorbable disaccharides...
Approved
Investigational
Matched Description: … Lactitol, also known as 4-β-D-galactopyranosyl-D-glucitol, is a sugar alcohol synthesized from [lactose ... [A190918] It is used in food manufacturing as a nutritive sweetener and is approximately 35% as sweet …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Sodium phosphate, monobasic
Sodium phosphate is a saline laxative that is thought to work by increasing fluid in the small intestine. It usually results in a bowel movement after 30 minutes to 6 hours.
Approved
Matched Description: … It usually results in a bowel movement after 30 minutes to 6 hours. ... Sodium phosphate is a saline laxative that is thought to work by increasing fluid in the small intestine …
Tixocortol
Tixocortol is a 21-thiol derivative of hydrocortisone classified as a class A corticosteroid. It is a synthetic steroid with topical anti-inflammatory properties without the systemic glucocorticoid and mineralocorticoid activities and toxicity.
Approved
Withdrawn
Matched Description: … Tixocortol is a 21-thiol derivative of hydrocortisone classified as a class A corticosteroid. ... It is a synthetic steroid with topical anti-inflammatory properties without the systemic glucocorticoid …
Idelalisib
Idelalisib is a phosphoinositide 3-kinase inhibitor indicated in the treatment of chronic lymphocytic leukemia (CLL), relapsed follicular B-cell non-Hodgkin lymphoma (FL), and relapsed small lymphocytic lymphoma (SLL). For the treatment of relapsed CLL, it is currently indicated as a second-line agent in combination with rituximab in patients for whom rituximab...
Approved
Matched Description: … Idelalisib is a phosphoinositide 3-kinase inhibitor indicated in the treatment of chronic lymphocytic ... For the treatment of relapsed CLL, it is currently indicated as a second-line agent in combination with ... The PI-3Ks are a family of enzymes involved in cellular functions such as cell growth, proliferation, …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A7 Substrates with a Narrow Therapeutic Index …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A7 Substrates with a Narrow Therapeutic Index …
Asparaginase Erwinia chrysanthemi
Asparaginase Erwinia chrysanthemi is an asparaginase-specific enzyme derived from Erwinia chrysanthemi used as an anticancer agent. It works by depleting the stores of an important amino acid called asparagine, which is involved in DNA synthesis and cell survival of malignant cells, leading to cell death. L-asparaginase was first identified in...
Approved
Investigational
Matched Description: … and there are different formulations of L-asparaginase, including [Asparaginase Escherichia coli] and a ... component of a chemotherapy regimen to treat acute lymphoblastic leukemia and lymphoblastic lymphoma ... In June 2021, the recombinant form of asparaginase _Erwinia chrysanthemi_ was approved by the FDA as a …
Esculin
Esculin is found in barley. Vitamin C2 is generally considered a bioflavanoid, related to vitamin P esculin is a glucoside that naturally occurs in the horse chestnut (Aesculus hippocastanum), California Buckeye (Aesculus californica) and in daphnin (the dark green resin of Daphne mezereum). Esculin belongs to the family of Glycosyl...
Approved
Matched Description: … Vitamin C2 is generally considered a bioflavanoid, related to vitamin P esculin is a glucoside that naturally ... group via a C-, S-,N-,O-, or Se- glycosidic bond. ... These are carbohydrate derivatives in which a sugar group is bonded through its anmoeric carbonA to another …
Diflunisal
Diflunisal, a salicylate derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with pharmacologic actions similar to other prototypical NSAIAs. Diflunisal possesses anti-inflammatory, analgesic and antipyretic activity. Though its mechanism of action has not been clearly established, most of its actions appear to be associated with inhibition of prostaglandin synthesis via the...
Approved
Investigational
Matched Description: … Diflunisal, a salicylate derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with pharmacologic …
Terconazole
Terconazole is an anti-fungal drug that is mainly used to treat vaginal yeast infections (or vaginal candidiasis). It is classified as a triazole ketal derivative. Terconazole was initially approved by the FDA in 1987.[FDA label] This drug is available in cream and suppository forms and both have demonstrated high levels...
Approved
Matched Description: … It is classified as a _triazole ketal derivative_. …
Displaying drugs 501 - 525 of 11951 in total