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Displaying drugs 526 - 550 of 15697 in total
Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal.[L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene monooxygenase (also called squalene epoxidase), an enzyme that is part of the fungal cell...
Approved
Investigational
Vet approved
Matched Synonyms: … (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalene methanamine ... (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethylamine …
Matched Iupac: … [(2E)-6,6-dimethylhept-2-en-4-yn-1-yl](methyl)[(naphthalen-1-yl)methyl]amine …
Matched Description: … Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal. ... [L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues …
Matched Mixtures name: … Fluconazole 4% / Ibuprofen 2% / Itraconazole 1% / Terbinafine HCl 4% …
Matched Categories: … Antifungals for Topical Use ... Antifungals for Systemic Use ... Antifungals for Dermatological Use …
Matched Products: … LOSIL-C ... DERMAN F-UNO ... Lamisil AT for Jock Itch …
A sulfonylurea hypoglycemic agent that is metabolized in the liver to 1-hydrohexamide. Acetohexamide has been discontinued in the US market.
Approved
Investigational
Withdrawn
Matched Synonyms: … 1-((p-Acetylphenyl)sulfonyl)-3-cyclohexylurea ... 1-[(4-acetylbenzene)sulfonyl]-3-cyclohexylurea 4-acetyl-N-(cyclohexylcarbamoyl)benzenesulfonamide …
Matched Iupac: … 1-(4-acetylbenzenesulfonyl)-3-cyclohexylurea …
Matched Description: … A sulfonylurea hypoglycemic agent that is metabolized in the liver to 1-hydrohexamide. ... Acetohexamide has been discontinued in the US market. …
Matched Categories: … Drugs Used in Diabetes …
Levomilnacipran is a selective serotonin and norepinephrine reuptake inhibitor (SNRI), although it is a more potent inhibitor of norepinephrine reuptake than serotonin reuptake.[A261181, A38560] Levomilnacipran is the more active 1S,2R-enantiomer in the racemate milnacipran.[A261181, L47956] Once administered, interconversion between levomilnacipran and its stereoisomer does not occur in humans. First approved...
Approved
Investigational
Matched Synonyms: … CYCLOPROPANECARBOXAMIDE, 2-(AMINOMETHYL)-N,N-DIETHYL-1-PHENYL-, (1S,2R)- …
Matched Iupac: … (1S,2R)-2-(aminomethyl)-N,N-diethyl-1-phenylcyclopropane-1-carboxamide …
Matched Description: … [L47956] While levomilnacipran was previously investigated and proposed as a potential treatment for ... a more potent inhibitor of norepinephrine reuptake than serotonin reuptake. ... stroke in Europe, the EMA decided against this use. …
Matched Categories: … Antidepressive Agents Indicated for Depression …
Rotigotine (Neupro) is a non-ergoline dopamine agonist indicated for the treatment of Parkinson's disease (PD) and restless legs syndrome (RLS) in Europe and the United States. It is formulated as a once-daily transdermal patch which provides a slow and constant supply of the drug over the course of 24 hours....
Approved
Matched Synonyms: … (6S)-6-(propyl(2-(2-thienyl)ethyl)amino)-5,6,7,8-tetrahydro-1-naphthalenol …
Matched Iupac: … (6S)-6-{propyl[2-(thiophen-2-yl)ethyl]amino}-5,6,7,8-tetrahydronaphthalen-1-ol …
Matched Description: … Rotigotine has been authorized as a treatment for RLS since August 2008. ... However, all Neupro patches in the United States and some of Europe were recalled in 2008 due to delivery ... Rotigotine (Neupro) is a non-ergoline dopamine agonist indicated for the treatment of Parkinson's disease …
Matched Salts cas: … 125572-93-2
Matched Products: … Rotigotin UCB 3 mg/24 Stunden transdermales Pflaster ... Rotigotin Gebro 3 mg/24 Stunden transdermales Pflaster ... นิวโปร 2 มก./ 24 ชม. แผ่นปิดผิวหนัง …
Xanthium strumarium var. canadense pollen is the pollen of the Xanthium strumarium var. canadense plant. Xanthium strumarium var. canadense pollen is mainly used in allergenic testing.
Approved
Matched Description: … Xanthium strumarium var. canadense pollen is mainly used in allergenic testing. …
Amoxapine, the N-demethylated derivative of the antipsychotic agent loxapine, is a dibenzoxazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, amoxapine does not affect mood or arousal, but may cause sedation....
Approved
Matched Synonyms: … 2-Chloro-11-(1-piperazinyl)dibenz(b,f)(1,4)oxazepine …
Matched Iupac: … 13-chloro-10-(piperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14-heptaene …
Matched Description: … See toxicity section below for a complete listing of side effects. ... In depressed individuals, amoxapine exerts a positive effect on mood. ... receptors, α1-adrenergic receptors and muscarinic receptors, which accounts for
Matched Categories: … Heterocyclic Compounds, 3-Ring ... Antidepressive Agents Indicated for Depression ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index …
Busulfan is a bifunctional alkylating agent, having a selective immunosuppressive effect on bone marrow. It is not a structural analog of the nitrogen mustards. It has been used in the palliative treatment of chronic myeloid leukemia (myeloid leukemia, chronic), but although symptomatic relief is provided, no permanent remission is brought...
Approved
Investigational
Matched Description: … It has been used in the palliative treatment of chronic myeloid leukemia (myeloid leukemia, chronic), ... Busulfan is a bifunctional alkylating agent, having a selective immunosuppressive effect on bone marrow ... It is not a structural analog of the nitrogen mustards. …
Matched Categories: … Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Products: … MYRAN TABLETS 2 mg ... Busulfan Kabi Injection 6mg/ml Concentrate for Solution for Infusion ... MYLERAN TABLETAS 2 MG …
An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
Approved
Investigational
Matched International brands: … E-Capro …
Matched Mixtures name: … NAVI Black and C-Clinic ... LACSIAN new perfect all care tooth ... Relief and Nature Toothpast E Jasmine Mint …
Eculizumab is a monoclonal antibody that targets complement protein C5.[L6919,A2245] Binding to this protein prevents the activation of a complement terminal complex, which is used to treat a number of autoimmune conditions.[L6919,A2245,A2246] Eculizumab was granted FDA approval on 16 March 2007. In Q1 2023, the EMA's Committee for Medicinal Products...
Approved
Investigational
Matched Description: … [L6919] In Q1 2023, the EMA's Committee for Medicinal Products for Human Use (CHMP) adopted a positive ... is used to treat a number of autoimmune conditions. ... Eculizumab is a monoclonal antibody that targets complement protein C5. …
Matched Products: … Soliris Concentrate for Solution for Infusion 300mg/vial …
Terlipressin is a synthetic analogue of vasopressin, which is an endogenous neurohormone that acts as a vasoconstrictor. It is a prodrug of lypressin, or lysine vasopressin. Compared to endogenous vasopressin, terlipressin has a longer half life and increased selectivity for the V1 receptor. As a potent vasopressor, terlipressin has been...
Approved
Investigational
Matched Description: … Compared to endogenous vasopressin, terlipressin has a longer half life and increased selectivity for ... [L43217] As a potent vasopressor, terlipressin has been investigated in various shock states and conditions ... a vasoconstrictor. …
Matched Products: … GLYPRESSIN FOR INJECTION 1 mg/vial ... GLYPRESSIN 1mg/8.5ml solution for injection ... GLYPRESSIN solution for injection, 1 mg/8.5 ml …
Viloxazine is a selective norepinephrine reuptake inhibitor. For decades, an immediate-release formulation of viloxazine has been used in Europe as an antidepressant. It was first approved in the UK in 1974; however, the immediate-release formulation was discontinued due to business reasons unrelated to drug safety and efficacy. In the US,...
Approved
Investigational
Withdrawn
Matched Synonyms: … 2-((2-Ethoxyphenoxy)methyl)morpholine …
Matched Iupac: … 2-[(2-ethoxyphenoxy)methyl]morpholine …
Matched Description: … Viloxazine is a selective norepinephrine reuptake inhibitor. ... [L41685] For decades, an immediate-release formulation of viloxazine has been used in Europe as an antidepressant ... by the FDA for the treatment of attention deficit hyperactivity disorder (ADHD). …
Matched Salts cas: … 35604-67-2
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates ... Monoamine Oxidase A Inhibitors …
A peptide that is a homopolymer of glutamic acid.
Approved
Nutraceutical
Matched Synonyms: … (2S)-2-Aminopentanedioic acid ... (S)-2-Aminopentanedioic acid …
Matched Iupac: … (2S)-2-aminopentanedioic acid …
Matched Description: … A peptide that is a homopolymer of glutamic acid. …
Matched Mixtures name: … Braun 10%E Solution for Intravenous Infusion ... AMINOPLASMAL B.BRAUN 10% E SOLUTION FOR INFUSION ... Aminosyn II in Dextrose …
Octocrylene is a compound often used as an additive in sun screen, and is thought to have skin moisturizing effects because of its emollient properties. What makes this chemical such a popular additive to sun block, is its ability to neutralize UV radiation dissipated by sunlight, and to minimize skin...
Approved
Investigational
Matched Iupac: … 2-ethylhexyl 2-cyano-3,3-diphenylprop-2-enoate …
Matched Description: … Because of its effectiveness, the chemical has been approved across the globe for use in cosmetics and ... Octocrylene is a compound often used as an additive in sun screen, and is thought to have skin moisturizing ... However, the use of this chemical doesn’t just stop with sunscreen for face and arms, but can extend …
Matched Mixtures name: … Derma-E Sensitive 3-in-1 sunscreen SPF 30 ... Hope In A Jar Broad Spectrum SPF 25 Sunscreen and Moisturizer for All Skin Types ... Hope In A Jar SPF 25 …
A sulfur containing essential amino acid that is important in many body functions. It is a chelating agent for heavy metals.
Approved
Nutraceutical
Matched Synonyms: … L-a-Amino-g-methylthiobutyric acid ... (S)-2-amino-4-(methylthio)butanoic acid ... (S)-2-amino-4-(methylthio)butyric acid …
Matched Iupac: … (2S)-2-amino-4-(methylsulfanyl)butanoic acid …
Matched Description: … It is a chelating agent for heavy metals. ... A sulfur containing essential amino acid that is important in many body functions. …
Matched Mixtures name: … AMINOMIX 3 SOLÜSYON, 1000 ML ... AMINOMIX 3 SOLÜSYON, 2000 ML ... AMINOMIX 3 SOLÜSYON, 15000 ML …
Methyl cellulose polymer consisting of numerous linked glucose molecules used as a stabiliser, thickener and emulsifier for foodstuffs and cosmetics. The Degree of Substitution (DS) of a given form of methyl cellulose is defined as the average number of substituted hydroxyl groups per glucose with a theoretical maximum of 3,...
Approved
Matched Description: … It is available under a variety of trade names as a treatment for constipation. ... Methyl cellulose is a hydrophilic white powder in pure form and dissolves in cold (but not in hot) water ... of substituted hydroxyl groups per glucose with a theoretical maximum of 3, however more typical values …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Drugs for Constipation …
Agalsidase alfa is a recombinant human α-galactosidase A similar to agalsidase beta. While patients generally do not experience a clinically significant difference in outcomes between the two drugs, some patients may experience greater benefit with agalsidase beta.[A220228,A220233] Use of agalsidase beta has decreased in Europe, in favor of agalsidase alfa,...
Approved
Matched Synonyms: … alpha-galactosidase A ... Recombinant alpha-galactosidase A
Matched Description: … a contamination event in 2009. ... [A220343] Agalsidase alfa was granted EMA approval on 3 August 2001.[L16413] ... While patients generally do not experience a clinically significant difference in outcomes between the …
Matched Products: … REPLAGAL CONCENTRATE FOR SOLUTION FOR INFUSION 1 MG/ML …
Recombinant zoster vaccine, manufactured as the product Shingrix by GlaxoSmithKline, is an adjuvanted non-live recombinant vaccine indicated for prevention of shingles. First approved in October 2017 by the Food and Drug Administration, Shingrix is the preferred vaccine for preventing varicella zoster infection in people aged 50 years and older, replacing...
Approved
Investigational
Matched Synonyms: … gE recombinant Varicella zoster virus (VZV) glycoprotein E ... Recombinant Varicella zoster virus (VZV) glycoprotein E ... gE: Recombinant Varicella Zoster Virus (VZV) glycoprotein E
Matched Description: … The main immunological component of Shingrix vaccine is glycoprotein E (gE), a protein found on the surface ... for preventing varicella zoster infection in people aged 50 years and older, replacing Zostavax as first ... Risk factors for developing shingles include old age, with rates increasing substantially in person's …
Matched Products: … SHINGRIX POWDER AND SUSPENSION FOR SUSPENSION FOR INJECTION 50MCG/0.5ML …
Tazobactam is an antibiotic of the beta-lactamase inhibitor class that prevents the breakdown of other antibiotics by beta-lactamase enzyme producing organisms. It is combined with Piperacillin and Ceftolozane for the treatment of a variety of bacterial infections. Piperacillin-tazobactam was initially approved by the FDA in 1994, and ceftolozane-tazobactam was approved...
Approved
Matched Iupac: … -2-carboxylic acid ... (2S,3S,5R)-3-methyl-4,4,7-trioxo-3-[(1H-1,2,3-triazol-1-yl)methyl]-4lambda6-thia-1-azabicyclo[3.2.0]heptane …
Matched Description: … It is combined with [Piperacillin] and [Ceftolozane] for the treatment of a variety of bacterial infections ... by the FDA in 2014[FDA label], providing wider antibacterial coverage for gram-negative infections. ... In June 2019, ceftolozane-tazobactam was approved by the FDA for treating hospital-acquired bacterial …
Matched Salts cas: … 89785-84-2
Matched Mixtures name: … Zosyn in Galaxy Containers ... Zosyn in Galaxy Containers ... Zosyn in Galaxy Containers …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Vandetanib is an oral once-daily kinase inhibitor of tumour angiogenesis and tumour cell proliferation with the potential for use in a broad range of tumour types. On April 6 2011, vandetanib was approved by the FDA to treat nonresectable, locally advanced, or metastatic medullary thyroid cancer in adult patients.
Approved
Matched Synonyms: … N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-((1-methyl-4-piperidinyl)methoxy)-4-quinazolinamine ... N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine …
Matched Iupac: … N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine …
Matched Description: … use in a broad range of tumour types. ... once-daily kinase inhibitor of tumour angiogenesis and tumour cell proliferation with the potential for ... approved by the FDA to treat nonresectable, locally advanced, or metastatic medullary thyroid cancer in
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Tetrofosmin was developed to overcome the non-target uptake of radioligands by the generation of hetero-atomic compounds. It presents a molecular formula of 1,2-bis(bis(2-ethoxyethyl)phosphino)ethane. Tetrofosmin is part of the group of diphosphines. Tetrofosmin is used in conjunction with technetium Tc-99m as a radiopharmaceutical.
Approved
Matched Iupac: … 6,9-bis(2-ethoxyethyl)-3,12-dioxa-6,9-diphosphatetradecane …
Matched Description: … It presents a molecular formula of 1,2-bis(bis(2-ethoxyethyl)phosphino)ethane. ... Tetrofosmin is used in conjunction with technetium Tc-99m as a radiopharmaceutical.[A7788] …
Matched Products: … MYOVIEW POWDER FOR INJECTION ... MYOVIEW FOR INJECTION 0.23 mg/vial …
Salmeterol is a long-acting beta-2 adrenergic receptor agonist drug that is currently prescribed for the treatment of asthma and chronic obstructive pulmonary disease COPD.[L11545,L11548,L11551,L11554,L11557] It has a longer duration of action than the short-acting beta-2 adrenergic receptor agonist, salbutamol. Salmeterol was first described in the literature in 1988. Salmeterol's structure...
Approved
Matched Iupac: … 4-(1-hydroxy-2-{[6-(4-phenylbutoxy)hexyl]amino}ethyl)-2-(hydroxymethyl)phenol …
Matched Description: … Salmeterol is a long-acting beta-2 adrenergic receptor agonist drug that is currently prescribed for ... [L11545,L11548,L11551,L11554,L11557] It has a longer duration of action than the short-acting beta-2 ... [A190459] Salmeterol was first described in the literature in 1988. …
Matched Salts cas: … 94749-08-3
Matched Mixtures name: … HOVID CLEFAN-S POWDER FOR INHALATION 50/250MCG ... AIRFLUSAL FORSPIRO POWDER FOR INHALATION 50MCG/500MCG ... SALMETEROLO E FLUTICASONE SF …
Matched Categories: … Drugs for Obstructive Airway Diseases ... Adrenergic beta-2 Receptor Agonists ... Selective Beta 2-adrenergic Agonists …
Inonotus obliquus fruiting body is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Description: … Inonotus obliquus fruiting body is a plant/plant extract used in some OTC (over-the-counter) products …
Amitriptyline is a tricyclic antidepressant that has been used to treat depression for decades. ELAVIL, a previously approved branded product of amitriptyline, was first approved by the FDA in 1961. Amitriptyline has been investigated in the treatment of pain-related conditions, attributed to its analgesic properties.
Approved
Matched Synonyms: … 5-(3-dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptene ... 5-(3-dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptatriene ... 3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine …
Matched Iupac: … dimethyl(3-{tricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaen-2-ylidene}propyl)amine …
Matched Description: … Amitriptyline is a tricyclic antidepressant that has been used to treat depression for decades. ... ELAVIL, a previously approved branded product of amitriptyline, was first approved by the FDA in 1961 ... [A259342] Amitriptyline has been investigated in the treatment of pain-related conditions, attributed …
Matched Salts cas: … 17086-03-2
Matched Mixtures name: … Etrafon A Tab ... Etrafon F Tab ... Apo Peram Tab 3-15 …
Matched Categories: … Antidepressive Agents Indicated for Depression ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic Index …
Approved
Vet approved
Matched Iupac: … ,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl acetate ... 2-[(1R,3aS,3bS,9aR,9bS,10S,11aS)-1,10-dihydroxy-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H …
Matched Mixtures name: … Alcortin A ... ZISUAL-C ... Alcortin A
Matched Products: … Poli-A ... Topiderm HC 2% ... Ekzemsalbe "F" - Agepha …
Turoctocog alfa pegol is a pegylated version of turoctocog alfa. Novo Nordisk's brand name Esperoct (turoctocog alfa pegol, N8-GP) was approved by the US FDA on February 19, 2019. Fundamentally, the N8-GP moiety is identical to turoctocog alfa, a recombinant human clotting factor VIII (rFVIII) with a truncated B-domain made...
Approved
Matched Description: … acid 720, and a monoclonal antibody binding C-terminal to this position is used in the purification ... A as it ultimately provides a less burdensome and more convenient dosing regimen for patients that is ... factor VIII replacement therapy in patients with factor VIII deficiency, or hemophilia A [F3649]. …
Displaying drugs 526 - 550 of 15697 in total