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Displaying drugs 526 - 550 of 877 in total

Azoximer bromide

Azoximer bromide is under investigation in clinical trial NCT04381377 (Efficacy and Safety of Polyoxidonium® in Hospitalized Patients With Coronavirus Disease COVID-19).
Investigational
Matched Synonyms: … Azoximer bromide ... Poly((1-(carboxymethyl)piperazin-1-ium-1,4-diyl bromide)ethylene-co-((piperazin-1,4-diyl 1-oxide)ethylene …
Matched Name: … Azoximer bromide …
Matched Description: … Azoximer bromide is under investigation in clinical trial NCT04381377 (Efficacy and Safety of Polyoxidonium …

Raltegravir

Raltegravir is an antiretroviral drug produced by Merck & Co., used to treat HIV infection. It received approval by the U.S. Food and Drug Administration (FDA) on 12 October 2007, the first of a new class of HIV drugs, the integrase inhibitors, to receive such approval.
Approved
Matched Description: … Food and Drug Administration (FDA) on 12 October 2007, the first of a new class of HIV drugs, the integrase …
Matched Salts name: … Raltegravir potassium …
Matched Categories: … lamivudine and raltegravir …
Matched Products: … Raltegravir Potassium …

Sodium carbonate

Sodium Carbonate is the disodium salt of carbonic acid with alkalinizing property. When dissolved in water, sodium carbonate forms carbonic acid and sodium hydroxide. As a strong base, sodium hydroxide neutralizes gastric acid thereby acting as an antacid.
Approved
Matched Synonyms: … Disodium carbonate ... Anhydrous sodium carbonate ... Sodium carbonate anhydrous …
Matched Name: … Sodium carbonate …
Matched Iupac: … disodium carbonate …
Matched Description: … When dissolved in water, sodium carbonate forms carbonic acid and sodium hydroxide. ... Sodium Carbonate is the disodium salt of carbonic acid with alkalinizing property. …

Ferrous carbonate

Experimental
Matched Name: … Ferrous carbonate …
Matched Iupac: … lambda2-iron(2+) carbonate …
Matched Categories: … Blood and Blood Forming Organs ... ferrous carbonate …

Trimethylene carbonate

Investigational
Matched Synonyms: … Cyclic trimethylene carbonate ... 1,3-propanediol, cyclic carbonate …
Matched Name: … Trimethylene carbonate …

Marzeptacog alfa (activated)

Marzeptacog alfa (activated) is under investigation in clinical trial NCT01439971 (Phase 1 Safety, Pharmacokinetics And Pharmacodynamics Study Of Recombinant Factor VIIa Variant (813d) In Adult Subjects With Hemophilia).
Investigational
Matched Synonyms: … Marzeptacog alfa (activated) …
Matched Name: … Marzeptacog alfa (activated) …
Matched Description: … And Pharmacodynamics Study Of Recombinant Factor VIIa Variant (813d) In Adult Subjects With Hemophilia ... Marzeptacog alfa (activated) is under investigation in clinical trial NCT01439971 (Phase 1 Safety, Pharmacokinetics …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …

LuLym-T

LuLym-T is an investigational autologous immune cell therapy consisting of activated T Lymphocytes. Developed by Lukas Biomedical, Inc., it is currently being investigated in hepatocellular carcinoma.
Investigational
Matched Synonyms: … Autologous Activated T Lymphocytes (ATL) …
Matched Description: … LuLym-T is an investigational autologous immune cell therapy consisting of activated T Lymphocytes. …

Cevostamab

Investigational
Matched Synonyms: … Anti-fcrh5/cd3 bite antibody bfcr4350a ... Fcrh5/cd3 t cell dependent bispecific antibody bfcr4350a ... Bfcr4350a (anti-fcrh5/cd3 t-cell dependent bispecific antibody) …

BI-836826

Investigational
Matched Synonyms: … ANTI-CD37 MONOCLONAL ANTIBODY BI 836826 …
Matched Categories: … Amino Acids, Peptides, and Proteins …

DR-01

DR-01 is a monoclonal antibody directed against human CD94.
Investigational
Matched Synonyms: … Human anti-CD94 IgG1 monoclonal antibody (non-fucosylated) …
Matched Description: … DR-01 is a monoclonal antibody directed against human CD94. …

Glofitamab

Glofitamab is a full-length bispecific monoclonal antibody with affinity for both CD20 and CD3 surface antigens found on B- and T-cells, respectively. It has a 2:1 configuration, with bivalency towards CD20 and monovalency towards CD3, and works by recruiting T-cells directly to the surface of cancerous B-cells.[L45698,A258488] Glofitamab was approved...
Approved
Investigational
Matched Synonyms: … Anti-CD20/CD3 bispecific monoclonal antibody RO7082859 …
Matched Description: … Glofitamab is a full-length bispecific monoclonal antibody with affinity for both CD20 and CD3 surface ... It has a 2:1 configuration, with bivalency towards CD20 and monovalency towards CD3, and works by recruiting ... antigens found on B- and T-cells, respectively. …
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …

Lomvastomig

Lomvastomig is under investigation in clinical trial NCT04785820 (A Study of Lomvastomig (RO7121661) and Tobemstomig (RO7247669) Compared With Nivolumab in Participants With Advanced or Metastatic Squamous Cell Carcinoma of the Esophagus).
Investigational
Matched Synonyms: … Anti-pd-1/tim-3 bispecific antibody ro7121661 …
Matched Description: … Lomvastomig is under investigation in clinical trial NCT04785820 (A Study of Lomvastomig (RO7121661) and …

Potassium iodate

Experimental
Matched Synonyms: … Iodic acid, potassium salt …
Matched Name: … Potassium iodate …
Matched Iupac: … potassium iodate …

Panobacumab

Panobacumab is under investigation in clinical trial NCT00851435 (Safety and Pharmacokinetics of KBPA-101 in Hospital Acquired Pneumonia Caused by O11 Pseudomonas Aeruginosa).
Investigational
Matched Synonyms: … Human monoclonal antibody directed against serotype 011 Pseudomonas aeruginosa ... Human monoclonal antibody directed against serotype O1 Pseudomonas aeruginosa …
Matched Description: … Panobacumab is under investigation in clinical trial NCT00851435 (Safety and Pharmacokinetics of KBPA …

Girentuximab

Girentuximab is a monoclonal chimeric (mouse/human) antibody directed against carbonic anhydrase IX, an antigen expressed in 95% of clear cell renal cell carcinomas (RCC).
Investigational
Matched Synonyms: … Chimeric (human-murine) G250 IgG monoclonal antibody …
Matched Description: … Girentuximab is a monoclonal chimeric (mouse/human) antibody directed against carbonic anhydrase IX, …
Matched Categories: … Amino Acids, Peptides, and Proteins …

ANX-005

Investigational
Matched Synonyms: … Humanized Igg4 Monoclonal Antibody Binding To Human C1Q …

LJP-538

Investigational
Matched Synonyms: … Human IgG1 anti-human cytomegalovirus monoclonal antibody LJP538 …

Rocatinlimab

Rocatinlimab is a subcutaneously administered anti-OX40 antibody developed for the treatment of moderate-to-severe atopic dermatitis. In clinical trials, it has shown significant efficacy and safety compared to a placebo. The drug works by targeting the OX40 receptor, which plays a role in the immune response associated with atopic dermatitis. Despite...
Investigational
Matched Synonyms: … Anti-CD134 human monoclonal antibody (IgG1, KHK4083 dimer) …
Matched Description: … Rocatinlimab is a subcutaneously administered anti-OX40 antibody developed for the treatment of moderate-to-severe ... injection reactions such as fever and chills have been reported. ... In clinical trials, it has shown significant efficacy and safety compared to a placebo. …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Vibecotamab

Vibecotamab is under investigation in clinical trial NCT05285813 (A Phase II Study of Vibecotamab (Xmab14045) for MRD- Positive AML and MDS After Hypomethylating Agent Failure).
Investigational
Matched Synonyms: … Anti-cd123 x anti-cd3 bispecific antibody xmab14045 …
Matched Description: … investigation in clinical trial NCT05285813 (A Phase II Study of Vibecotamab (Xmab14045) for MRD- Positive AML and …

SAR-439459

SAR-439459 is a pan-transforming Growth Factor-beta (TGFβ) neutralizing antibody. Developed by Sanofi, it is being investigated for the treatment of cancers and Osteogenesis Imperfecta.
Investigational
Matched Synonyms: … ANTI-TGF-BETA MONOCLONAL ANTIBODY SAR-439459 …
Matched Description: … [A259862] Developed by Sanofi, it is being investigated for the treatment of cancers and Osteogenesis ... SAR-439459 is a pan-transforming Growth Factor-beta (TGFβ) neutralizing antibody. …

Perflubron

Perflubron (Oxygent) is being developed as an intravascular oxygen carrier designed to augment oxygen delivery in surgical patients.
Investigational
Matched Synonyms: … Perfluorooctyl-bromide …

ABBV-011

ABBV-011 is an antibody-drug conjugate of humanized, cysteine-engineered IgG1 monoclonal antibody targeting seizure-related 6 homolog conjugated to N-acetyl-gamma-calicheamicin.
Investigational
Matched Synonyms: … an antibody-drug conjugate of humanized, cysteine-engineered IgG1 monoclonal antibody targeting seizure-related …
Matched Description: … ABBV-011 is an antibody-drug conjugate of humanized, cysteine-engineered IgG1 monoclonal antibody targeting …

Tomaralimab

Tomaralimab is under investigation in clinical trial NCT01794663 (Placebo-Controlled Study to Evaluate the Safety and Efficacy of OPN-305 in Preventing Delayed Renal Graft Function).
Investigational
Matched Synonyms: … anti-Tlr2 monoclonal antibody OPN-305 ... Humanized IGG4 monoclonal antibody against toll-like receptor 2 for prevention of ischemia/reperfusion …
Matched Description: … under investigation in clinical trial NCT01794663 (Placebo-Controlled Study to Evaluate the Safety and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Norepinephrine

Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is...
Approved
Matched Description: … Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic ... It is also found in plants and is used pharmacologically as a sympathomimetic. ... Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse …
Matched Categories: … Adrenergic and Dopaminergic Agents ... Epinephrine and similars ... Alpha-and Beta-adrenergic Agonists …
Matched Products: … NORADRENALINA TARTRATO MONICO ... NORADRENALINA TARTRATO SUN ... NORADRENALINA TARTRATO S.A.L.F. …

Levorphanol

A narcotic analgesic that may be habit-forming. It is nearly as effective orally as by injection.
Approved
Matched Salts name: … Levorphanol tartrate …
Matched Products: … Levorphanol Tartrate …
Displaying drugs 526 - 550 of 877 in total