Displaying drugs 526 - 550 of 1984 in total
Felbamate
Felbamate is an anticonvulsant drug used in the treatment of epilepsy. In particular, in the adult patient population, it can be employed to treat partial seizures (with and without generalization). Alternatively, it is used to treat partial and generalized seizures associated with Lennox-Gastaut syndrome in children. It has a weak...
Approved
Matched Synonyms: … 2-phenyl-1,3-propanediol dicarbamate ... Carbamic acid 3-carbamoyloxy-2-phenyl-propyl ester …
Matched Description: … In particular, in the adult patient population, it can be employed to treat partial seizures (with and ... Alternatively, it is used to treat partial and generalized seizures associated with Lennox-Gastaut syndrome …
Matched Description: … In particular, in the adult patient population, it can be employed to treat partial seizures (with and ... Alternatively, it is used to treat partial and generalized seizures associated with Lennox-Gastaut syndrome …
Alidornase alfa
Investigational
Matched Synonyms: … Deoxyribonuclease (synthetic human), amide with 1,2-ethanediamine …
Crisdesalazine
Investigational
Matched Synonyms: … 2-hydroxy-5-((2-(4-(trifluoromethyl)phenyl)ethyl)amino)benzoic acid ... Benzoic acid, 2-hydroxy-5-((2-(4-(trifluoromethyl)phenyl)ethyl)amino)- …
Matched Iupac: … 2-hydroxy-5-({2-[4-(trifluoromethyl)phenyl]ethyl}amino)benzoic acid …
Matched Categories: … Phenols …
Matched Iupac: … 2-hydroxy-5-({2-[4-(trifluoromethyl)phenyl]ethyl}amino)benzoic acid …
Matched Categories: … Phenols …
Propafenone
An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity. The drug is generally well tolerated.
Approved
Matched Synonyms: … 1-(2-(2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-1-propanone …
Matched Iupac: … 1-{2-[2-hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one …
Matched Iupac: … 1-{2-[2-hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one …
Antazoline
Antazoline is a 1st generation antihistamine with anticholinergic activity. It is used to relieve nasal congestion. It is also formulated as eye drops with naphazoline to relieve allergic conjunctivitis.
Approved
Matched Synonyms: … 2-(N-Phenyl-N-benzylaminomethyl)imidazoline ... 4,5-Dihydro-N-phenyl-N-phenylmethyl-1H-imidazole-2-methanamine …
Matched Categories: … Antihistamines for Systemic Use …
Matched Categories: … Antihistamines for Systemic Use …
Miransertib
Miransertib is under investigation in clinical trial NCT01473095 (Phase 1 Dose Escalation Study of ARQ 092 in Adult Subjects With Advanced Solid Tumors and Recurrent Malignant Lymphoma).
Investigational
Matched Synonyms: … 3-{3-[4-(1-aminocyclobutyl)phenyl]-5-phenyl-3H-imidazo[4,5-b]pyridin-2-yl}pyridin-2-amine …
Matched Iupac: … 3-{3-[4-(1-aminocyclobutyl)phenyl]-5-phenyl-3H-imidazo[4,5-b]pyridin-2-yl}pyridin-2-amine …
Matched Description: … NCT01473095 (Phase 1 Dose Escalation Study of ARQ 092 in Adult Subjects With Advanced Solid Tumors and …
Matched Iupac: … 3-{3-[4-(1-aminocyclobutyl)phenyl]-5-phenyl-3H-imidazo[4,5-b]pyridin-2-yl}pyridin-2-amine …
Matched Description: … NCT01473095 (Phase 1 Dose Escalation Study of ARQ 092 in Adult Subjects With Advanced Solid Tumors and …
Etoricoxib
Etoricoxib is a new COX-2 selective inhibitor. Current therapeutic indications are: treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout. Like any other COX-2 selective inhibitor, Etoricoxib selectively inhibits isoform 2 of cyclo-oxigenase enzyme (COX-2) to reduce the generation of prostaglandins (PGs) from arachidonic...
Approved
Investigational
Matched Synonyms: … 5-chloro-2-(6-methylpyridin-3-yl)-3-(4-(methylsulfonyl)phenyl)pyridine ... 5-Chloro-3-(4-methanesulfonyl-phenyl)-6'-methyl-[2,3']bipyridinyl ... 5-chloro-6'-methyl-3-(p-(methylsulfonyl)phenyl)-2,3'-bipyridine …
Matched Description: … of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Description: … of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Sodium chloride
Sodium chloride, also known as salt, common salt, table salt or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions. Sodium chloride is the primary salt in seawater and in the extracellular fluid of many multicellular organisms. It is listed...
Approved
Vet approved
Matched Description: … or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and ... Sodium chloride is the primary salt in seawater and in the extracellular fluid of many multicellular …
Matched Mixtures name: … Diluent for Allergenic Extract Sterile Normal Saline With Phenol (0.4%) ... Phenol Saline Inj ... Glycerinated Phenol Saline …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …
Matched Products: … Walgreens Infants and Childrens Saline Nasal ... DILUTE FOR EPOPROSTENOL FOR INTRAVENOUS INJECTION ... Sodium Chloride for Irrigation …
Matched Mixtures name: … Diluent for Allergenic Extract Sterile Normal Saline With Phenol (0.4%) ... Phenol Saline Inj ... Glycerinated Phenol Saline …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …
Matched Products: … Walgreens Infants and Childrens Saline Nasal ... DILUTE FOR EPOPROSTENOL FOR INTRAVENOUS INJECTION ... Sodium Chloride for Irrigation …
Propyphenazone
Experimental
Matched Synonyms: … 1-Phenyl-2,3-dimethyl-4-isopropylpyrazol-5-one ... 1-Phenyl-2,3-dimethyl-4-isopropyl-3-pyrazolin-5-one ... 4-Isopropyl-1,5-dimethyl-2-phenyl-1,2-dihydro-pyrazol-3-one …
Matched Iupac: … 1,5-dimethyl-2-phenyl-4-(propan-2-yl)-2,3-dihydro-1H-pyrazol-3-one …
Matched Iupac: … 1,5-dimethyl-2-phenyl-4-(propan-2-yl)-2,3-dihydro-1H-pyrazol-3-one …
Antipyrine
An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
Approved
Investigational
Matched Synonyms: … 2,3-Dimethyl-1-phenyl-5-pyrazolone ... 1,2-Dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one …
Matched Iupac: … 1,5-dimethyl-2-phenyl-2,3-dihydro-1H-pyrazol-3-one …
Matched Description: … An analgesic and antipyretic that has been given by mouth and as ear drops. …
Matched Mixtures name: … Antipyrine and Benzocaine ... Antipyrine and Benzocaine ... Antipyrine and Benzocaine …
Matched Categories: … Analgesics and Anesthetics …
Matched Iupac: … 1,5-dimethyl-2-phenyl-2,3-dihydro-1H-pyrazol-3-one …
Matched Description: … An analgesic and antipyretic that has been given by mouth and as ear drops. …
Matched Mixtures name: … Antipyrine and Benzocaine ... Antipyrine and Benzocaine ... Antipyrine and Benzocaine …
Matched Categories: … Analgesics and Anesthetics …
PI-103
PI-103 is an inhibitor of p110α of class I PI3K.
Investigational
Matched Synonyms: … Phenol, 3-(4-(4-morpholinyl)pyrido(3',2':4,5)furo(3,2-d)pyrimidin-2-yl)- …
Matched Iupac: … -[6-(morpholin-4-yl)-8-oxa-3,5,10-triazatricyclo[7.4.0.0^{2,7}]trideca-1(13),2,4,6,9,11-hexaen-4-yl]phenol …
Matched Iupac: … -[6-(morpholin-4-yl)-8-oxa-3,5,10-triazatricyclo[7.4.0.0^{2,7}]trideca-1(13),2,4,6,9,11-hexaen-4-yl]phenol …
Ocriplasmin
Ocriplasmin is a recombinant truncated form of human plasmin with a molecular weight of 27.2 kDa produced by recombinant DNA technology in a Pichia pastoris expression system. Ocriplasmin is a protein made up of 249 amino acids and has two peptide chains. Agent for pharmacologic vitreolysis; thrombolytic agent. FDA approved...
Approved
Matched Synonyms: … Microplasmin (synthetic human) …
Matched Description: … Ocriplasmin is a protein made up of 249 amino acids and has two peptide chains. ... Agent for pharmacologic vitreolysis; thrombolytic agent. FDA approved in October 17, 2012. ... Ocriplasmin is a recombinant truncated form of human plasmin with a molecular weight of 27.2 kDa produced …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Matched Description: … Ocriplasmin is a protein made up of 249 amino acids and has two peptide chains. ... Agent for pharmacologic vitreolysis; thrombolytic agent. FDA approved in October 17, 2012. ... Ocriplasmin is a recombinant truncated form of human plasmin with a molecular weight of 27.2 kDa produced …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Lirafugratinib
Investigational
Matched Synonyms: … 6-yl)phenyl)methacrylamide ... -d]pyrimidin-6-yl]phenyl]-2-methyl- ... -6- yl)phenyl]-2-methylprop-2-enamide …
Matched Iupac: … 6-yl)phenyl]-2-methylprop-2-enamide ... N-[4-(4-amino-5-{3-fluoro-4-[(4-methylpyrimidin-2-yl)oxy]phenyl}-7-methyl-7H-pyrrolo[2,3-d]pyrimidin- …
Matched Iupac: … 6-yl)phenyl]-2-methylprop-2-enamide ... N-[4-(4-amino-5-{3-fluoro-4-[(4-methylpyrimidin-2-yl)oxy]phenyl}-7-methyl-7H-pyrrolo[2,3-d]pyrimidin- …
LY-294002
Specific inhibitor of phosphatidylinositol 3-kinase.
Experimental
Matched Synonyms: … 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one …
Matched Iupac: … 2-(morpholin-4-yl)-8-phenyl-4H-chromen-4-one …
Matched Iupac: … 2-(morpholin-4-yl)-8-phenyl-4H-chromen-4-one …
Captodiame
Captodiame, also known as captodiamine, is an antihistamine which is used as a sedative and anxiolytic. It is a derivative of diphenhydramine. Captodiame has been suggested for use in preventing benzodiazepine withdrawal syndrome.
Experimental
Matched Synonyms: … 2-[(4-butylsulfanylphenyl)-phenyl-methyl]sulfanyl-N,N-dimethylethanamine …
Matched Iupac: … [2-({[4-(butylsulfanyl)phenyl](phenyl)methyl}sulfanyl)ethyl]dimethylamine …
Matched Description: … Captodiame, also known as captodiamine, is an antihistamine which is used as a sedative and anxiolytic ... Captodiame has been suggested for use in preventing benzodiazepine withdrawal syndrome. …
Matched Iupac: … [2-({[4-(butylsulfanyl)phenyl](phenyl)methyl}sulfanyl)ethyl]dimethylamine …
Matched Description: … Captodiame, also known as captodiamine, is an antihistamine which is used as a sedative and anxiolytic ... Captodiame has been suggested for use in preventing benzodiazepine withdrawal syndrome. …
Amedalin
Amedalin is a selective norepinephrine reuptake inhibitor developed in the 1970s. It has no significant effect on reuptake of serotonin and dopamine and no antihistamine or anticholinergic properties. This drug was never marketed.
Experimental
Matched Synonyms: … 3-methyl-3-(3-(methylamino)propyl)-1-phenyl-2-indolinone …
Matched Iupac: … (3S)-3-methyl-3-[3-(methylamino)propyl]-1-phenyl-2,3-dihydro-1H-indol-2-one …
Matched Description: … It has no significant effect on reuptake of serotonin and dopamine and no antihistamine or anticholinergic …
Matched Iupac: … (3S)-3-methyl-3-[3-(methylamino)propyl]-1-phenyl-2,3-dihydro-1H-indol-2-one …
Matched Description: … It has no significant effect on reuptake of serotonin and dopamine and no antihistamine or anticholinergic …
Isoflavone
Isoflavone is a soy phytoestrogen and a biologically active component of several agriculturally important legumes such as soy, peanut, green peas, chick peas and alfalfa . Soybean is an exceptionally rich source of dietary isoflavones, where the average isoflavone content is 1-2 mg/gram . The main soy isoflavones are mostly...
Experimental
Matched Synonyms: … 3-phenyl-4H-1-benzopyran-4-one …
Matched Iupac: … 3-phenyl-4H-chromen-4-one …
Matched Description: … The main soy isoflavones are mostly present in glycosylated forms and include [DB01645], [DB13182], and ... glycitein, which accounts for approximately 50%, 40%, and 10%, respectively, of the total soybean isoflavone ... The clinical benefits of soy proteins have been studied and demonstrated for many years, with some evidence …
Matched Mixtures name: … ISOFEM FORTE TABLETAS RECUBIERTAS …
Matched Iupac: … 3-phenyl-4H-chromen-4-one …
Matched Description: … The main soy isoflavones are mostly present in glycosylated forms and include [DB01645], [DB13182], and ... glycitein, which accounts for approximately 50%, 40%, and 10%, respectively, of the total soybean isoflavone ... The clinical benefits of soy proteins have been studied and demonstrated for many years, with some evidence …
Matched Mixtures name: … ISOFEM FORTE TABLETAS RECUBIERTAS …
Pegilodecakin
Pegilodecakin is under investigation in clinical trial NCT03382912 (Study of Pegilodecakin (LY3500518) With Nivolumab Compared to Nivolumab Alone Second-line Tx in Participants With Metastatic Non-Small Cell Lung Cancer).
Investigational
Matched Synonyms: … INTERLEUKIN 10 (SYNTHETIC HUMAN), DIMER, N-TERMINAL 5-KILODALTON PEGYLATED …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Elacestrant
Elacestrant is a non-steroidal small molecule and an estrogen receptor (ER) antagonist.[A256838,L44918] In January 2023, it was approved by the FDA for the treatment of ER-positive, HER2-negative, ESR1-mutated advanced or metastatic breast cancer.[L44918,L44948] It received a similar approval in the EU in September 2023. Elacestrant binds to estrogen receptor-alpha (ERα)...
Approved
Investigational
Matched Synonyms: … (2R)-2-(2-(ethyl-((4-(2-(ethylamino)ethyl)phenyl)methyl)amino)-4-methoxy-phenyl)tetralin-6-ol ... (6R)-6-(2-(ethyl((4-(2- (ethylamino)ethyl)phenyl)methyl)amino)-4-methoxyphenyl)- 5,6,7,8-tetrahydronaphthalen ... 2-naphthalenol, 6-(2-(ethyl((4-(2-(ethylamino)ethyl)phenyl)methyl)amino)-4-methoxyphenyl)-5,6,7,8-tetrahydro …
Matched Iupac: … (6R)-6-{2-[ethyl({4-[2-(ethylamino)ethyl]phenyl}methyl)amino]-4-methoxyphenyl}-5,6,7,8-tetrahydronaphthalen …
Matched Description: … Elacestrant is a non-steroidal small molecule and an estrogen receptor (ER) antagonist. ... [L49334] Elacestrant binds to estrogen receptor-alpha (ERα) and acts as a selective estrogen receptor ... degrader (SERD) thanks to its ability to block the transcriptional activity of the ER and promote its …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents …
Matched Iupac: … (6R)-6-{2-[ethyl({4-[2-(ethylamino)ethyl]phenyl}methyl)amino]-4-methoxyphenyl}-5,6,7,8-tetrahydronaphthalen …
Matched Description: … Elacestrant is a non-steroidal small molecule and an estrogen receptor (ER) antagonist. ... [L49334] Elacestrant binds to estrogen receptor-alpha (ERα) and acts as a selective estrogen receptor ... degrader (SERD) thanks to its ability to block the transcriptional activity of the ER and promote its …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents …
Phenmetrazine
A sympathomimetic drug used primarily as an appetite depressant. Its actions and mechanisms are similar to dextroamphetamine.
Approved
Illicit
Matched Synonyms: … 2-phenyl-3-methylmorpholine …
Matched Description: … Its actions and mechanisms are similar to dextroamphetamine. …
Matched Description: … Its actions and mechanisms are similar to dextroamphetamine. …
TAS-303
Investigational
Matched Synonyms: … -PHENYL-.ALPHA.-(PROPOXY-1,1,2,2,3,3,3-D7)BENZENEACETATE …
BG-P400-TAT
Investigational
Matched Synonyms: … )-ethyl]-1H-[1,2,3]triazol-4-ylmethoxy}-3,5-diiodo-phenoxy)-3,5-diiodo-phenyl]-acetic acid ... [4-(4-{1-[2-(2-{2-[2-(2-{2-[2-(4-guanidinomethyl-phenoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethoxy ... 2-[4-[4-[[1-[2-[2-[2-[2-[2-[2-[2-[4-[(Diaminomethylideneamino)methyl]phenoxy]ethoxy]ethoxy]ethoxy]ethoxy …
Matched Iupac: … 2-(4-{4-[(1-{20-[4-(carbamimidamidomethyl)phenoxy]-3,6,9,12,15,18-hexaoxaicosan-1-yl}-1H-1,2,3-triazol …
Matched Iupac: … 2-(4-{4-[(1-{20-[4-(carbamimidamidomethyl)phenoxy]-3,6,9,12,15,18-hexaoxaicosan-1-yl}-1H-1,2,3-triazol …
Montelukast
Montelukast was first approved for clinical use by the US FDA in 1998 as Merck's brand name Singulair. The medication is a member of the leukotriene receptor antagonist (LTRA) category of drugs.[L6301,L6304,L6307,L6310,L6325,L6328,L6331] Although capable of demonstrating effectiveness, the use of such LTRAs like montelukast is typically in addition to or...
Approved
Matched Synonyms: … (R-(E))-1-(((1-(3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl ... 1-[[[(1 R)-1-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl] phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl] …
Matched Iupac: … 2-[1-({[(1R)-1-{3-[(1E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl}-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl …
Matched Description: … via millions of prescriptions annually and has since become available as a generic and as a brand name ... montelukast to elicit neuropsychiatric effects like agitation, hallucinations, suicidal behaviour, and ... [A178651] And although these kinds of effects are currently included in the official prescribing information …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Drugs for Obstructive Airway Diseases …
Matched Iupac: … 2-[1-({[(1R)-1-{3-[(1E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl}-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl …
Matched Description: … via millions of prescriptions annually and has since become available as a generic and as a brand name ... montelukast to elicit neuropsychiatric effects like agitation, hallucinations, suicidal behaviour, and ... [A178651] And although these kinds of effects are currently included in the official prescribing information …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Drugs for Obstructive Airway Diseases …
Displaying drugs 526 - 550 of 1984 in total