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Displaying drugs 526 - 550 of 5212 in total
Aminopterin is an amino derivative of folic acid, which was once used as an antineoplastic agent in the treatment of pediatric leukemia. In the 1950's its production was discontinued in favor of methotrexate, which is less potent but less toxic. Off label, aminopterin has also been used in the treatment...
Investigational
Withdrawn
Matched Synonyms: … N-(4-(((2,4-diamino-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid ... 4-aminofolic acid ... 4-aminopteroylglutamic acid
Matched Iupac: … (2S)-2-[(4-{[(2,4-diaminopteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acid
Matched Description: … Clinicians need to be aware of the characteristic teratologic effects of aminopterin and methotrexate ... Aminopterin is an amino derivative of folic acid, which was once used as an antineoplastic agent in the …
Matched Categories: … Folic Acid Antagonists …
Iptacopan is a small-molecule factor B inhibitor previously investigated as a potential treatment for the rare blood disease paroxysmal nocturnal hemoglobinuria (PNH) by inhibiting the complement factor B. Factor B is a positive regulator of the alternative complement pathway, where it activates C3 convertase and subsequently C5 convertase. This is...
Approved
Investigational
Matched Synonyms: … 4-((2S,4S)-4-ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl) benzoic acid ... BENZOIC ACID, 4-((2S,4S)-4-ETHOXY-1-((5-METHOXY-7-METHYL-1H-INDOL-4-YL)METHYL)-2-PIPERIDINYL)- …
Matched Iupac: … 4-[(2S,4S)-4-ethoxy-1-[(5-methoxy-7-methyl-1H-indol-4-yl)methyl]piperidin-2-yl]benzoic acid
Matched Description: … Factor B is a positive regulator of the alternative complement pathway, where it activates C3 convertase and ... that normally anchor 2 membrane proteins, CD55 and CD59, that protect blood cells against the alternative ... benefit of targeting factor B, which only affect the alternative complement pathway, leaving the classic and
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C8 Substrates ... Cytochrome P-450 CYP2D6 Substrates …
Approved
Experimental
Matched Synonyms: … acide linoléique ... Linolic acid ... (9Z,12Z)-Octadecadienoic acid
Matched Name: … Linoleic acid
Matched Iupac: … (9Z,12Z)-octadeca-9,12-dienoic acid
Matched Mixtures name: … SIMILAC ALIMENTUM 400 G TOZ …
Matched Categories: … Fatty Acids ... Linoleic Acids ... Fatty Acids, Essential ... Fatty Acids, Omega-6 ... Fatty Acids, Unsaturated …
Investigational
Matched Synonyms: … (3-((1-cyclohexyl-4-oxo-8-(4-oxo-4-phenylbutyl)-1,3,8 triazaspiro(4.5) decan-3-yl)methyl)benzoic acid ... Benzoic acid, 3-((1-cyclohexyl-4-oxo-8-(4-oxo-4-phenylbutyl)-1,3,8-triazaspiro(4.5)dec-3-yl)methyl)- …
Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID) for ophthalmic use. Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. Their well-characterized anti-inflammatory activity, analgesic property, and established safety record have also made NSAIDs an important tool for optimizing surgical outcomes. Non-ophthalmic formulations of bromfenac were...
Approved
Withdrawn
Matched Synonyms: … [2-Amino-3-(4-bromo-benzoyl)-phenyl]-acetic acid ... 2-amino-3-(4-bromobenzoyl)benzeneacetic acid
Matched Iupac: … 2-[2-amino-3-(4-bromobenzoyl)phenyl]acetic acid
Matched Description: … Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. ... Their well-characterized anti-inflammatory activity, analgesic property, and established safety record …
Trofinetide is a novel synthetic analog of glypromate, also known as glycine–proline–glutamate (GPE), a naturally occurring protein in the brain and the N-terminal tripeptide of insulin-like growth factor 1 (IGF-1). Trofinetide was approved by the FDA on March 10, 2023, for the treatment of Rett syndrome,[L45718,L45748] which is an X-linked...
Approved
Investigational
Matched Synonyms: … glycyl-L-2-methylprolyl-L-glutamic acid
Matched Iupac: … (2S)-2-{[(2S)-1-(2-aminoacetyl)-2-methylpyrrolidin-2-yl]formamido}pentanedioic acid
Matched Description: … glypromate], also known as glycine–proline–glutamate (GPE), a naturally occurring protein in the brain and ... [A258438] Trofinetide is believed to work by reducing inflammation and apoptosis of neurons. ... L45748] which is an X-linked neurodevelopmental disorder characterized by a range of cognitive, motor, and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Amino Acids, Dicarboxylic ... Cytochrome P-450 CYP3A Inhibitors …
Experimental
Matched Name: … 4-[(METHYLSULFONYL)AMINO]BENZOIC ACID
Matched Iupac: … 4-methanesulfonamidobenzoic acid
Radiopaque medium used in the diagnosis of gall bladder & bile duct diseases, usually as meglumine salt.
Experimental
Matched Synonyms: … Iodoxamic acid ... Acidum iodoxamicum …
Matched Name: … Iodoxamic acid
Matched Iupac: … 3-carboxy-2,4,6-triiodophenyl)carbamoyl]-3,6,9,12-tetraoxapentadecan-15-amido}-2,4,6-triiodobenzoic acid
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... iodoxamic acid
An antitubercular agent often administered in association with isoniazid. The sodium salt of the drug is better tolerated than the free acid.
Approved
Matched Synonyms: … 4-aminosalicylic acid ... 4-amino-2-hydroxybenzoic acid ... 4-aminosalicylate …
Matched Name: … Aminosalicylic acid
Matched Iupac: … 4-amino-2-hydroxybenzoic acid
Matched Description: … The sodium salt of the drug is better tolerated than the free acid. …
Matched Categories: … Aminosalicylic Acid and Derivatives ... 4-aminosalicylic acid ... Acids, Carbocyclic ... Aminosalicylic Acids ... Hydroxy Acids
Experimental
Matched Synonyms: … 4-hydroxybenzenesulfonic acid ... 4-Sulfophenol ... Phenolsulfonic acid
Matched Name: … Phenolsulfonic acid
Matched Iupac: … 4-hydroxybenzene-1-sulfonic acid
Gamma hydroxybutyric acid, commonly abbreviated GHB, is a therapeutic drug which is illegal in multiple countries. It is currently regulated in the US and sold by Jazz Pharmaceuticals under the name Xyrem. However, it is important to note that GHB is a designated Orphan drug (in 1985). Today Xyrem is...
Approved
Illicit
Investigational
Matched Synonyms: … 4-hydroxy-butyric acid ... 4-Hydroxybutyric acid ... 4-hydroxybutanoic acid
Matched Name: … gamma-Hydroxybutyric acid
Matched Iupac: … 4-hydroxybutanoic acid
Matched Description: … Gamma hydroxybutyric acid, commonly abbreviated GHB, is a therapeutic drug which is illegal in multiple ... It is currently regulated in the US and sold by Jazz Pharmaceuticals under the name Xyrem. ... Today Xyrem is a Schedule III drug; however GHB remains a Schedule I drug and the illicit use of Xyrem …
Matched Salts cas: … 57769-01-4
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Fatty Acids ... Hydroxy Acids ... Fatty Acids, Volatile …
Investigational
Matched Synonyms: … Fumaric acid ... Fumaricum acidum ... (2E)-2-butenedioic acid
Matched Name: … Fumaric acid
Matched Iupac: … (2E)-but-2-enedioic acid
Matched Categories: … Acids, Acyclic ... fumaric acid ... Carboxylic Acids ... Dicarboxylic Acids
Experimental
Matched Synonyms: … 4-toluenesulfonic acid ... toluene-4-sulfonic acid ... Tosic acid
Matched Name: … p-Toluenesulfonic acid
Matched Iupac: … 4-methylbenzene-1-sulfonic acid
Matched Categories: … Arylsulfonic Acids ... Sulfur Acids ... Sulfonic Acids
Experimental
Matched Synonyms: … 4-coumaric acid ... 4-Hydroxycinnamic acid ... trans-4-coumaric acid
Matched Name: … p-Coumaric acid
Matched Iupac: … (2E)-3-(4-hydroxyphenyl)prop-2-enoic acid
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids
Experimental
Matched Synonyms: … (E)-4-(3-Oxo-3-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid
Matched Iupac: … 4-[(1E)-3-oxo-3-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)prop-1-en-1-yl]benzoic acid
Experimental
Matched Synonyms: … (4-nitrophenyl)acetic acid ... 4-nitrobenzeneacetic acid ... 4-nitrophenylacetic acid
Matched Name: … p-Nitrophenylacetic acid
Matched Iupac: … 2-(4-nitrophenyl)acetic acid
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids
Experimental
Matched Synonyms: … 4-[2-Acetylamino-2-(1-biphenyl-4-ylmethyl-2-oxo-azepan-3-ylcarbamoyl)-ethyl]-2-formyl-benzoic acid
Matched Iupac: … acid ... 4-[(2S)-2-{[(3S)-1-({[1,1'-biphenyl]-4-yl}methyl)-2-oxoazepan-3-yl]carbamoyl}-2-acetamidoethyl]-2-formylbenzoic …
Methotrexate is a folate derivative that inhibits several enzymes responsible for nucleotide synthesis. This inhibition leads to suppression of inflammation as well as prevention of cell division. Because of these effects, methotrexate is often used to treat inflammation caused by arthritis or to control cell division in neoplastic diseases such...
Approved
Matched Synonyms: … N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid ... 4-amino-10-methylfolic acid ... 4-amino-N(10)-methylpteroylglutamic acid
Matched Iupac: … acid ... (2S)-2-[(4-{[(4-amino-2-imino-2,3-dihydropteridin-6-yl)methyl](methyl)amino}phenyl)formamido]pentanedioic …
Matched Description: … inflammation caused by arthritis or to control cell division in neoplastic diseases such as breast cancer and ... Due to the toxic effects of methotrexate, it is indicated for treatment of some forms of arthritis and
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Folic Acid Analogues ... Folic Acid Antagonists ... Nucleic Acid Synthesis Inhibitors ... Cytochrome P-450 Substrates …
Matched Products: … METHOTREXAT 'EBEWE' PFS 20 MG/2 ML KULLANIMA HAZIR ENJEKTÖR, 4 ADET ... METHOTREXAT 'EBEWE' PFS 10 MG/1 ML KULLANIMA HAZIR ENJEKTÖR, 4 ADET ... METHOTREXAT 'EBEWE' PFS 15 MG/1,5 ML KULLANIMA HAZIR ENJEKTÖR, 4 ADET …
Etidronic acid is a first generation bisphosphonate similar to clodronic acid and tiludronic acid. These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. Etidronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate zoledronic acid, ibandronic acid,...
Approved
Matched Synonyms: … Etidronic acid ... acide étidronique ... acidum etidronicum …
Matched Name: … Etidronic acid
Matched Iupac: … (1-hydroxy-1-phosphonoethyl)phosphonic acid
Matched Description: … Etidronic acid is a first generation bisphosphonate similar to [clodronic acid] and [tiludronic acid] ... ], [ibandronic acid], [minodronic acid], and [risedronic acid]. ... A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and
Matched Categories: … etidronic acid and calcium, sequential ... Drugs Affecting Bone Structure and Mineralization ... etidronic acid
Matched Products: … DIDRONAT 200 MG TABLET, 60 ADET ... DIDRONAT 400 MG TABLET, 30 ADET …
Experimental
Matched Synonyms: … 2-(4-morpholinyl)ethanesulfonic acid ... 4-morpholinethanesulfonic acid ... 4-morpholineethanesulfonic acid
Matched Name: … 2-(N-morpholino)ethanesulfonic acid
Matched Iupac: … 4-(2-sulfonatoethyl)morpholin-4-ium …
Matched Categories: … Sulfur Acids ... Sulfonic Acids
Experimental
Matched Synonyms: … 2,3-diphytanyl-sn-glycerol ... 2,3-Di-O-phytanyl-sn-glycerol
Matched Name: … 2,3-di-O-phytanyl-sn-glycerol
Investigational
Matched Synonyms: … Benzoic acid, 4-((15-oxoretin-15-yl)amino)- ... N-4-carboxyphenylretinamide ... Retinamide, n-(4-carboxyphenyl)- …
Matched Name: … Retinamidic acid
Matched Iupac: … acid ... 4-[(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenamido]benzoic
Phenylbutyric acid is a fatty acid and a derivative of butyric acid naturally produced by colonic bacteria fermentation. It demonstrates a number of cellular and biological effects, such as relieving inflammation and acting as a chemical chaperone. It is used to treat genetic metabolic syndromes, neuropathies, and urea cycle disorders.[L386,L42105]
Approved
Investigational
Matched Synonyms: … 4-phenylbutyric acid ... 4-Phenyl-n-butyric acid ... 4-phenylbutyrate …
Matched Name: … Phenylbutyric acid
Matched Iupac: … 4-phenylbutanoic acid
Matched Description: … Phenylbutyric acid is a fatty acid and a derivative of [butyric acid] naturally produced by colonic bacteria ... It demonstrates a number of cellular and biological effects, such as relieving inflammation and acting ... [A249035] It is used to treat genetic metabolic syndromes, neuropathies, and urea cycle disorders. …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Alimentary Tract and Metabolism ... sodium phenylbutyrate and ursodoxicoltaurine ... Various Alimentary Tract and Metabolism Products …
Nitarsone is an organoarsenic compound. It is used as an additive in poultry feed to improve weight gain and feed efficiency, while preventing blackhead disease. It is marketed as Histostat by Zoetis, a publicly traded subsidiary of Pfizer.
Vet approved
Matched Synonyms: … 4-nitrobenzenearsonic acid ... 4-nitrophenylarsonic acid ... (p-nitrophenyl)arsonic acid
Matched Iupac: … (4-nitrophenyl)arsonic acid
Matched Description: … It is used as an additive in poultry feed to improve weight gain and feed efficiency, while preventing …
Experimental
Matched Synonyms: … (4R)-4-Thiazolidinecarboxylic acid ... (R)-4-Thiazolidinecarboxylic acid ... L-Thiazolidine-4-carboxylic acid
Matched Iupac: … (4R)-1,3-thiazolidine-4-carboxylic acid
Displaying drugs 526 - 550 of 5212 in total