Displaying drugs 526 - 550 of 609 in total
CI-1040
CI-1040 has been used in trials studying the treatment of Lung Cancer, Breast Cancer, Breast Neoplasms, Pancreatic Cancer, and Colorectal Cancer, among others.
Investigational
Matched Categories: … Calcium-Calmodulin-Dependent Protein Kinases …
Mitiglinide
Mitiglinide is a drug for the treatment of type 2 diabetes. It may stimulate insulin secretion in beta-cells by closing off ATP dependant potassium ion channels.
Investigational
Matched Salts name: … Mitiglinide calcium dihydrate …
Dotarizine
Investigational
Matched Categories: … Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents …
1alpha,24S-Dihydroxyvitamin D2
LR-103 is a naturally occurring D-hormone that is produced by the kidneys from vitamin D. LR-103 is one of the D-hormones produced from Hectorol. It is developed for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease (CKD). Studies have shown LR-103 has the same potency as calcitriol,...
Investigational
Calcitonin porcine
Calcitonin is a polypeptide hormone secreted by the parafollicular cells of the thyroid gland in mammals. It inhibits bone resorption and lowers both serum and urinary calcium concentrations. Human calcitonin is available only in very small quantities but has been used in some studies. The first commercially available preparation in...
Experimental
Matched Description: … It inhibits bone resorption and lowers both serum and urinary calcium concentrations. …
Matched Categories: … Calcium Homeostasis …
Matched Categories: … Calcium Homeostasis …
Quisqualic acid
Quisqualic acid is an agonist at two subsets of excitatory amino acid receptors, ionotropic receptors that directly control membrane channels and metabotropic receptors that indirectly mediate calcium mobilization from intracellular stores. The compound is obtained from the seeds and fruit of Quisqualis chinensis.
Experimental
Matched Description: … receptors that directly control membrane channels and metabotropic receptors that indirectly mediate calcium …
Caroverine
Experimental
Matched Categories: … Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents …
t-Butylhydroquinone
Experimental
Matched Categories: … Calcium-Transporting ATPases, antagonists & inhibitors …
Aranidipine
Aranidipine is a novel dihydropyridine derivative that gives rise to two active metabolites (M-1α and M-1β) that exhibit hypotensive activity. It is a calcium antagonist with the formula methyl 2-oxopropyl 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylate. It was developed by Maruko Seiyaku, introduced by Taiho and launched in Japan in 1997.
Experimental
Matched Description: … It is a calcium antagonist with the formula methyl 2-oxopropyl 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl …
Matched Categories: … Calcium Channel Blockers …
Matched Categories: … Calcium Channel Blockers …
Doxofylline
Doxofylline is a methylxanthine derivative with the presence of a dioxolane group in position 7. As a drug used in the treatment of asthma, doxofylline has shown similar efficacy to theophylline but with significantly fewer side effects in animal and human studies. In contrast with other xanthine derivatives, doxofylline does...
Experimental
Matched Description: … Unlike theophylline, doxofylline does not affect calcium influx and does not antagonize the actions of ... calcium channel blockers which could explain reduced cardiac adverse reactions associated with the drug …
Evocalcet
Evocalcet has been used in trials studying the treatment of Hyperparathyroidism and Secondary Hyperparathyroidism.
Investigational
Matched Categories: … Calcium Homeostasis …
Eperisone
Eperisone is an antispasmodic drug which relaxes both skeletal muscles and vascular smooth muscles, and demonstrates a variety of effects such as reduction of myotonia, improvement of circulation, and suppression of the pain reflex. It is not approved for use in the United States, but is available in other countries...
Investigational
Matched Categories: … Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents …
Terodiline
Experimental
Matched Categories: … Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents …
2,5-di-tert-butylhydroquinone
Experimental
Matched Categories: … Calcium-Transporting ATPases, antagonists & inhibitors …
Iroxanadine
BRX-235 (iroxanadine) is a a novel small molecule synthesized by Biorex, Hungary that acts as a cardioprotective agent. It induces phosphorylation of p38 SAPK, which plays an important role in EC homeostasis. endothelial cell (EC). EC function plays a central role in vascular diseases (e.g. atherosclerosis, restenosis, diabetic angiopathies, microvascular...
Investigational
Matched Description: … BRX-235 also causes translocation of calcium-dependent protein kinase C isoform to membranes. …
Tetrandrine
Experimental
Matched Categories: … Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents …
Tolperisone
Tolperisone is an oral, centrally acting muscle relaxant. Its precise mechanism is not completely understood, though it blocks sodium and calcium channels. It possesses a high affinity for nervous system tissue, reaching highest concentrations in brain stem, spinal cord and peripheral nerves. Based on existing clinical data, Tolperisone is not...
Investigational
Matched Description: … Its precise mechanism is not completely understood, though it blocks sodium and calcium channels. …
Naftopidil
Naftopidil has been investigated for the treatment of Disorder of Urinary Stent.
Investigational
Matched Categories: … Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents …
PD-98059
PD-98059 is an inhibitor of MAP-kinase kinase activation.
Investigational
Matched Categories: … Calcium-Calmodulin-Dependent Protein Kinases, antagonists & inhibitors …
Salirasib
Salirasib has been used in trials studying the diagnostic of Carcinoma, Non-Small-Cell Lung.
Investigational
Matched Categories: … Calcium-Calmodulin-Dependent Protein Kinases, antagonists & inhibitors …
Sparteine
Sparteine is a plant alkaloid derived from Cytisus scoparius and Lupinus mutabilis which may chelate calcium and magnesium. It is a sodium channel blocker, so it falls in the category of class 1a antiarrhythmic agents. Sparteine is not currently FDA-approved for human use, and its salt, sparteine sulfate, is one...
Experimental
Withdrawn
Matched Description: … Sparteine is a plant alkaloid derived from _Cytisus scoparius_ and _Lupinus mutabilis_ which may chelate calcium …
Tranilast
Tranilast is an antiallergic drug developed by Kissei Pharmaceuticals. In 1982, it was approved in Japan and South Korea for the management of bronchial asthma. Indications for keloid and hypertrophic scar were added in 1993. It has been used for the treatment of allergic disorders such as asthma, allergic rhinitis...
Investigational
Matched Categories: … Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents …
Morniflumate
Morniflumate is a non-steroidal anti-inflammatory drug with antipyretic properties. It is the morpholinoethyl ester of niflumic acid . In one study, post morniflumate ingestion, physical examination and clinical symptoms of those with bronchitis showed improvement .
Experimental
Otilonium
Experimental
Investigational
Matched Categories: … Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents …
24,25-Dihydroxycholecalciferol
Investigational
Matched Categories: … Calcium-Regulating Hormones and Agents …
Displaying drugs 526 - 550 of 609 in total