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Displaying drugs 526 - 550 of 4237 in total
DS-1211 is a potent and selective novel small molecule tissue-nonspecific alkaline phosphatase (TNAP) inhibitor.
Investigational
Matched Synonyms: … N-Acetyl-D-leucine ... N-Acetyl-R-leucine ... D-leucine, N-acetyl- …
Matched Iupac: … (2R)-2-acetamido-4-methylpentanoic acid
Matched Description: … DS-1211 is a potent and selective novel small molecule tissue-nonspecific alkaline phosphatase (TNAP) …
Experimental
Matched Synonyms: … D-N-(4-Hydroxyphenyl)glycine ... (R)-ethyl 2-amino-2-(4-hydroxyphenyl)acetate ... (R)-alpha-Amino-4-hydroxybenzeneacetic acid
Matched Iupac: … (2R)-2-amino-2-(4-hydroxyphenyl)acetic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids
Cycloleucine is non-metabolisable amino acid formed by cyclization of leucine. It is also a specific and reversible inhibitor of nucleic acid methylation and widely used in biochemical experiments.
Experimental
Matched Synonyms: … Cyclo-leucine ... 1-amino-1-cyclopentanecarboxylic acid ... 1-aminocyclopentanecarboxylic acid
Matched Iupac: … 1-aminocyclopentane-1-carboxylic acid
Matched Description: … Cycloleucine is non-metabolisable amino acid formed by cyclization of leucine. ... It is also a specific and reversible inhibitor of nucleic acid methylation and widely used in biochemical …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic …
Levodopa is a prodrug of dopamine that is administered to patients with Parkinson's due to its ability to cross the blood-brain barrier[Label]. Levodopa can be metabolised to dopamine on either side of the blood-brain barrier and so it is generally administered with a dopa decarboxylase inhibitor like carbidopa to prevent...
Approved
Matched Synonyms: … Dihydroxy-L-phenylalanine ... 3,4-Dihydroxy-L-phenylalanine ... β-(3,4-dihydroxyphenyl)alanine
Matched Iupac: … (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoic acid
Matched Description: … Levodopa can be metabolised to dopamine on either side of the blood-brain barrier and so it is generally ... Once past the blood-brain barrier, levodopa is metabolized to dopamine and supplements the low endogenous ... The first developed drug product that was approved by the FDA was a levodopa and carbidopa combined product …
Matched Mixtures name: … LEVOCAENT-NX 100/25/200 ... LEVOCAENT-NX 100/25/200 ... LEVOCAENT-NX 100/25/200 …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Dopa and Dopa Derivatives ... levodopa and decarboxylase inhibitor ... levodopa, decarboxylase inhibitor and COMT inhibitor ... Amino Acids
Experimental
Matched Synonyms: … (2S,3R)-2-amino-3-methylpentanoic acid ... allo-L-isoleucine
Matched Iupac: … (2S,3R)-2-amino-3-methylpentanoic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Branched-Chain …
Experimental
Matched Synonyms: … N,N-Dihydroxyethyl glycine ... Diethanol glycine ... N,N-Dihydroxyethylglycine …
Matched Iupac: … 2-[bis(2-hydroxyethyl)amino]acetic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids
Acetic acid C-11 is under investigation in clinical trial NCT01953965 (Look at Way the Heart Functions in People With Pulmonary Hypertension (PH) Who Have Near Normal Right Ventricle (RV) Function and People With Pulmonary Hypertension Who Have Impaired RV Function. Using Imaging Studies PET Scan and Cardiac MRI.).
Investigational
Matched Synonyms: … [11C]Acetic Acid ... 11C-ACETATE
Matched Name: … Acetic acid C-11 …
Matched Iupac: … (1-11C)acetic acid
Matched Description: … Using Imaging Studies PET Scan and Cardiac MRI.). ... in People With Pulmonary Hypertension (PH) Who Have Near Normal Right Ventricle (RV) Function and People ... Acetic acid C-11 is under investigation in clinical trial NCT01953965 (Look at Way the Heart Functions …
Pidolic acid is a naturally occurring but little-studied amino acid derivative that can be formed enzymatically or non-enzymatically and participates as a biological intermediate with unique pharmacodynamics in various chemical pathways [A32991, L2729]. Elevations of the acid in blood levels may be associated with problems of glutamine or glutathione metabolism...
Approved
Investigational
Matched Synonyms: … Glutimic acid ... 5-oxo-L-proline ... Pidolic acid
Matched Name: … Pidolic acid
Matched Iupac: … (2S)-5-oxopyrrolidine-2-carboxylic acid
Matched Description: … or non-enzymatically and participates as a biological intermediate with unique pharmacodynamics in various ... Pidolic acid, in general, is found in large quantities in brain tissue and other tissues in bound form ... Elevations of the acid in blood levels may be associated with problems of glutamine or glutathione metabolism …
Matched Mixtures name: … 2% Salicylic Acid FACIAL CLEANSER …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Amino Acids, Acidic ... Amino Acids ... Imino Acids
Ziltivekimab is under investigation in clinical trial NCT06200207 (A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation).
Investigational
Matched Synonyms: … Immunoglobulin g1 (255-tyrosine,257-threonine,259-glutamic acid), anti-(human interleukin 6) (human monoclonal …
Matched Description: … Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Approved
Matched Synonyms: … Acido oxidronico ... Oxidronic acid ... Acidum oxidronicum …
Matched Name: … Oxidronic acid
Matched Iupac: … [hydroxy(phosphono)methyl]phosphonic acid
Medroxyprogesterone acetate (MPA) is a progesterone derivative that is more resistant to metabolism for improved pharmacokinetic properties. MPA can be use to treat secondary amenorrhea, endometrial hyperplasia, abnormal uterine bleeding, osteoporosis, vasomotor symptoms in menopause, vulvar and vaginal atrophy, prevent pregnancy, manage pain in endometriosis, prevent pregnancy, and is also...
Approved
Investigational
Matched Synonyms: … Medroxyprogesterone acetate ... Medroxyprogesterone 17-acetate ... 17α-hydroxy-6α-methylprogesterone acetate
Matched Name: … Medroxyprogesterone acetate
Matched Iupac: … 11a-trimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl acetate
Matched Description: … in palliative care for endometrial and renal carcinoma. ... endometrial hyperplasia, abnormal uterine bleeding, osteoporosis, vasomotor symptoms in menopause, vulvar and ... vaginal atrophy, prevent pregnancy, manage pain in endometriosis, prevent pregnancy, and is also used …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Combination Contraceptives (with Estrogen and derivatives) ... Hormones and Related Agents ... Progesterone and Derivatives ... Genito Urinary System and Sex Hormones …
Matched Products: … Nu-medroxy ... Medroxyprogesterone Acetate ... Medroxyprogesterone acetate
Flunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. It is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an adjuvant in the therapy of epilepsy.
Approved
Matched Description: … Flunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 ... peripheral origin, and as an adjuvant in the therapy of epilepsy. ... effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and
Matched Categories: … Calcium-Regulating Hormones and Agents ... Histamine Agents ... Histamine Antagonists ... Histamine H1 Antagonists …
Matched Products: … FLUNARIZIN ACIS 5MG ... FLUNARIZIN ACIS 10MG ... NATIL N 5MG …
An essential amino acid. It is often added to animal feed. [PubChem]
Experimental
Matched Synonyms: … D-Lysin ... (R)-2,6-diaminohexanoic acid ... D-2,6-Diaminohexanoic acid
Matched Name: … D-Lysine
Matched Iupac: … (2R)-2,6-diaminohexanoic acid
Matched Description: … An essential amino acid. It is often added to animal feed. [PubChem] …
Neuren Pharmaceuticals was developing Glypromate (glycine-proline glutamate), a naturally occurring small-molecule neuroprotectant derived from IGF-1 which inhibits caspase III dependent apoptosis, for the potential treatment of neurodegenerative diseases by IV infusion. In December 2008, the company discontinued further development of the drug after it failed to show an observable effect.
Investigational
Matched Synonyms: … Glycyl-prolyl-glutamic acid
Matched Iupac: … (2S)-2-{[(2S)-1-(2-aminoacetyl)pyrrolidin-2-yl]formamido}pentanedioic acid
Matched Description: … Neuren Pharmaceuticals was developing Glypromate (glycine-proline glutamate), a naturally occurring small-molecule …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Synonyms: … (3S)-3-methyl-L-aspartic acid ... 2S,3S-3-methylaspartic acid
Matched Name: … threo-3-methyl-L-aspartic acid
Matched Iupac: … (2S,3S)-2-amino-3-methylbutanedioic acid
Experimental
Matched Synonyms: … Methionine sulfone ... (S)-Amino-4-(methylsulphonyl)butyric acid ... L-2-amino-4-(methylsulfonyl)butanoic acid
Matched Name: … L-methionine sulfone …
Matched Iupac: … (2S)-2-amino-4-methanesulfonylbutanoic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Neutral ... Amino Acids, Sulfur …
Trofinetide is a novel synthetic analog of glypromate, also known as glycine–proline–glutamate (GPE), a naturally occurring protein in the brain and the N-terminal tripeptide of insulin-like growth factor 1 (IGF-1). Trofinetide was approved by the FDA on March 10, 2023, for the treatment of Rett syndrome,[L45718,L45748] which is an X-linked...
Approved
Investigational
Matched Synonyms: … glycyl-L-2-methylprolyl-L-glutamic acid
Matched Iupac: … (2S)-2-{[(2S)-1-(2-aminoacetyl)-2-methylpyrrolidin-2-yl]formamido}pentanedioic acid
Matched Description: … ), a naturally occurring protein in the brain and the N-terminal tripeptide of insulin-like growth factor ... Trofinetide is a novel synthetic analog of [glypromate], also known as glycineproline–glutamate (GPE ... [A258438] Trofinetide is believed to work by reducing inflammation and apoptosis of neurons. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Amino Acids, Dicarboxylic …
An anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint disorders and administered by mouth and topically. (From Martindale, The Extra Pharmacopoeia, 30th ed, p16)
Approved
Matched Synonyms: … acide flufénamique ... Flufenamic acid ... Acidum flufenamicum …
Matched Name: … Flufenamic acid
Matched Iupac: … 2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid
Matched Description: … An anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. ... It is used in musculoskeletal and joint disorders and administered by mouth and topically. …
Matched Categories: … Antiinflammatory and Antirheumatic Products, Non-Steroids ... Antiinflammatory and Antirheumatic Products ... Acids, Carbocyclic ... Carboxylic Acids ... flufenamic acid
Eprodisate slows the decline of renal function in AA amyloidosis.
Investigational
Matched Synonyms: … Propane-1,3-disulfonic acid ... 1,3-propanedisulfonic acid ... Propane-1,3-disulfonate …
Matched Iupac: … propane-1,3-disulfonic acid
Matched Categories: … Acids ... Sulfur Acids ... Acids, Noncarboxylic …
Methotrexate is a folate derivative that inhibits several enzymes responsible for nucleotide synthesis. This inhibition leads to suppression of inflammation as well as prevention of cell division. Because of these effects, methotrexate is often used to treat inflammation caused by arthritis or to control cell division in neoplastic diseases such...
Approved
Matched Synonyms: … N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid ... 4-amino-N(10)-methylpteroylglutamic acid ... 4-amino-10-methylfolic acid
Matched Iupac: … -[(4-{[(4-amino-2-imino-2,3-dihydropteridin-6-yl)methyl](methyl)amino}phenyl)formamido]pentanedioic acid
Matched Description: … inflammation caused by arthritis or to control cell division in neoplastic diseases such as breast cancer and ... Due to the toxic effects of methotrexate, it is indicated for treatment of some forms of arthritis and ... non-Hodgkin's lymphoma. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Folic Acid Analogues ... Folic Acid Antagonists ... Nucleic Acid Synthesis Inhibitors …
Omega-3 fatty acids are polyunsaturated fatty acids (PUFAs) with a double bond at the third carbon atom from the end of the carbon chain. The three types of omega-3 fatty acids involved in human physiology are α-linolenic acid (ALA) (found in plant oils), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA)...
Approved
Nutraceutical
Matched Synonyms: … n-3 fatty acids ... Omega-3 (n-3) polyunsaturated fatty acids ... Omega-3 acid
Matched Name: … Omega-3 fatty acids
Matched Description: … in plant oils), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA) (both commonly found in ... Omega-3 fatty acids play a critical role in metabolism and cellular function and they are available as ... Food and Drug Administration gave "qualified health claim" status to EPA and DHA omega-3 fatty acids. …
Matched Mixtures name: … Prenatal Vitamin No 53 Iron Fum Folic Acid Docusate CA DHA ... UltimateCare ONE NF
Matched Categories: … Alimentary Tract and Metabolism ... Bile and Liver Therapy ... Fatty Acids ... Fatty Acids, Omega-3 ... Fatty Acids, Unsaturated …
Experimental
Matched Synonyms: … Pipemidic acid ... acido pipemidico …
Matched Name: … Pipemidic acid
Matched Iupac: … 8-ethyl-5-oxo-2-(piperazin-1-yl)-5H,8H-pyrido[2,3-d]pyrimidine-6-carboxylic acid
Matched Salts name: … Pipemidic acid trihydrate …
Matched Categories: … Acids, Heterocyclic ... Nicotinic Acids ... pipemidic acid
Matched Products: … ACIDO PIPEMIDICO EG ... ACIDO PIPEMIDICO AUROBINDO ... ACIDO PIPEMIDICO DR. REDDY'S …
Investigational
Matched Synonyms: … Acido orotico ... Orotic acid ... Acidum oroticum …
Matched Name: … Orotic acid
Matched Iupac: … 2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid
Matched Categories: … Acids, Heterocyclic …
Experimental
Matched Synonyms: … N-(Aminocarbonyl)-L-phenylalanine ... (-)-N-Carbamoylphenylalanine …
Matched Name: … N-Carbamoylphenylalanine …
Matched Iupac: … (2S)-2-(carbamoylamino)-3-phenylpropanoic acid
Experimental
Matched Synonyms: … 3-[N-[Benzyloxycarbonyl]-phenylalaninyl-amino]-5-phenyl-pentane-1-sulfonic acid 4-nitro-phenyl ester …
Matched Name: … 4-Nitrophenyl (3S)-3-({N-[(benzyloxy)carbonyl]-L-phenylalanyl}amino)-5-phenyl-1-pentanesulfonate …
Matched Iupac: … benzyl N-[(1S)-1-{[(3S)-1-[(4-nitrophenoxy)sulfonyl]-5-phenylpentan-3-yl]carbamoyl}-2-phenylethyl]carbamate …
Displaying drugs 526 - 550 of 4237 in total