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Displaying drugs 5576 - 5600 of 6892 in total

Eldecalcitol

Eldecalcitol (ED-71), a vitamin D analog, is a more potent inhibitor of bone resorption than alfacalcidol in an estrogen-deficient rat model of osteoporosis. Eldecalcitol, effectively and safely increased lumbar and hip bone mineral density (BMD) in osteoporotic patients who also received vitamin D3 supplementation.
Investigational

Girentuximab

Girentuximab is a monoclonal chimeric (mouse/human) antibody directed against carbonic anhydrase IX, an antigen expressed in 95% of clear cell renal cell carcinomas (RCC).
Investigational

Valopicitabine

The 3-O-valine ester prodrug of the nucleoside analog 2'-C-methylcytidine with anti-hepatitis C virus (HCV) activity. Upon administration, valopicitabine is converted into 2'-C-methylcytidine; upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and viral RNA-dependent RNA polymerase activity. This blocks viral production of HCV RNA and thus...
Experimental
Matched Synonyms: … 2'-C-methylcytidine 3'-O-L-valinyl ester …
Matched Description: … The 3-O-valine ester prodrug of the nucleoside analog 2'-C-methylcytidine with anti-hepatitis C virus ... Upon administration, valopicitabine is converted into 2'-C-methylcytidine; upon phosphorylation into …

AQ-13

AQ-13 is an 4-aminoquinoline analog being investigated for the treatment of malaria.
Investigational

Rocatinlimab

Rocatinlimab is a subcutaneously administered anti-OX40 antibody developed for the treatment of moderate-to-severe atopic dermatitis. In clinical trials, it has shown significant efficacy and safety compared to a placebo. The drug works by targeting the OX40 receptor, which plays a role in the immune response associated with atopic dermatitis. Despite...
Investigational

Pyrazolanthrone

Experimental

Brefeldin A

A metabolite from Penicillium brefeldianum that exhibits a wide range of antibiotic activity.
Experimental

Molgramostim

Molgramostim has been used in trials studying the treatment of Bronchiectasis, Cystic Fibrosis, Pulmonary Alveolar Proteinosis, Acute Respiratory Distress Syndrome, and Autoimmune Pulmonary Alveolar Proteinosis.
Investigational

Modakafusp alfa

Modakafusp alfa is under investigation in clinical trial NCT03215030 (A Study to Investigate the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of TAK-573 in Participants With Refractory Multiple Myeloma (MM)).
Investigational

GliSODin

Investigational
Nutraceutical

E1v1.11

E1v1.11 is an antisense oligonucleotide targeting the SMN2 gene which is under investigation for the treatment of spinal muscular atrophy (SMA).
Investigational

Trans-O-Hydroxy-Alpha-Methyl Cinnamate

Experimental

[4,6-O-(1-CARBOXYETHYLIDENE)-BETA-D-MANNOSE]

Experimental

2',6'-DIFLUOROBIPHENYL-4-CARBOXYLIC ACID

Experimental

Neoantigen specific TCR-T cell therapy

Investigational

1h-Benoximidazole-2-Carboxylic Acid

Experimental

Guanosine-2',3'-cyclophosphorothioate

Experimental

4'-FLUORO-1,1'-BIPHENYL-4-CARBOXYLIC ACID

Experimental

7,8-dihydroxy-4-phenyl-2H-chromen-2-one

Experimental

2-(4-CHLORO-PHENYLAMINO)-NICOTINIC ACID

Experimental

Human umbilical tissue derived cells

Investigational

PL-3994

PL-3994 is under investigation in clinical trial NCT01304628 (Cross-Over Study of Subcutaneous Study Drug for the Treatment of Patients With Mild to Moderate Asthma).
Investigational
Matched Iupac: … 2-[(4R,7S,10S,13S,16S,19R,22S,28R,31S,34S,37S)-31-benzyl-10-[(2S)-butan-2-yl]-19-butyl-13,22-bis(3-carbamimidamidopropyl …

9-amino-n-[3-(dimethylamino)propyl]acridine-4-carboxamide

9-amino-n-[3-(dimethylamino)propyl]acridine-4-carboxamide is an inactive derivative of the antitumour agents N-[2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA) and 9-amino-DACA.
Experimental

Diphthamide

Experimental

Triapine

Triapine has been used in trials studying the treatment of Leukemia, Lung Cancer, Kidney Cancer, Prostate Cancer, and Pancreatic Cancer, among others.
Investigational
Displaying drugs 5576 - 5600 of 6892 in total