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Displaying drugs 551 - 575 of 772 in total
There is a great deal of evidence indicating that vascular endothelial growth factor (VEGF) is important for the survival and proliferation of cancer cells.[A192939,A192837,A192891,A193275] VEGF plays an important role in angiogenesis, lymphangiogenesis, and tumor growth, which are all factors that contribute to its attractiveness as a therapeutic target for anti-cancer...
Approved
Investigational
Matched Synonyms: … Anti-VEGF monoclonal antibody ... Anti-VEGF Humanized Monoclonal Antibody
Matched Description: … [A193272,A193275] It is a humanized monoclonal IgG antibody, and inhibits angiogenesis by binding and ... of evidence indicating that vascular endothelial growth factor (VEGF) is important for the survival and ... [A192939,A192837,A192891,A193275] VEGF plays an important role in angiogenesis, lymphangiogenesis, and
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Vascular Endothelial Growth Factor-directed Antibody Interactions …
EMB-01 is under investigation in clinical trial NCT03797391 (A Dose Escalation Study of EMB-01 in Participants With Advanced/metastatic Solid Tumors).
Investigational
Matched Synonyms: … Anti-egfr/c-met bispecific antibody emb-01 ... Anti-egfr/anti-c-met bispecific antibody emb-01 …
MK-4721 is a fully human monoclonal antibody directed to Agensys’ proprietary target Prostate Stem Cell Antigen (PSCA), an antigen expressed at significant levels on tumor cells from the majority of patients with all stages of prostate, pancreatic and bladder cancers.
Investigational
Matched Synonyms: … ANTI-PSCA MONOCLONAL ANTIBODY AGS-1C4D4 …
Matched Description: … MK-4721 is a fully human monoclonal antibody directed to Agensys’ proprietary target Prostate Stem Cell ... significant levels on tumor cells from the majority of patients with all stages of prostate, pancreatic and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … Recombinant anti-CD40 monoclonal antibody
Matched Categories: … Amino Acids, Peptides, and Proteins …
Ruplizumab is a humanized monoclonal antibody used as an immunosuppressive drug and is a component of Antova.
Investigational
Matched Synonyms: … Recombinant humanized monoclonal antibody 5c8 …
Matched Description: … Ruplizumab is a humanized monoclonal antibody used as an immunosuppressive drug and is a component of …
Matched Categories: … Amino Acids, Peptides, and Proteins …
MEDI-6469 is a monoclonal antibody under investigation in clinical trial NCT02205333 (A Phase 1b/2 Safety and Tolerability of MEDI6469 in Combination With Therapeutic Immune Agents or Monoclonal Antibodies).
Investigational
Matched Synonyms: … Agonistic anti-OX40 monoclonal antibody MEDI6469 …
Matched Description: … and Tolerability of MEDI6469 in Combination With Therapeutic Immune Agents or Monoclonal Antibodies) ... MEDI-6469 is a monoclonal antibody under investigation in clinical trial NCT02205333 (A Phase 1b/2 Safety …
Ivuxolimab is under investigation in clinical trial NCT02554812 (A Study of Avelumab in Combination With Other Cancer Immunotherapies in Advanced Malignancies (JAVELIN Medley)).
Investigational
Matched Synonyms: … Anti-OX40 Antibody PF-04518600 …
Odronextamab is a hinge-stabilized, fully human immunoglobulin G4 (IgG4)-based CD20×CD3 bispecific antibody currently evaluated for the treatment of relapsed/refractory (R/R) B-Cell non-Hodgkin lymphoma (NHL).[A254187,A254197] Preliminary studies have shown that in patients with R/R NHL, the use of odronextamab does not lead to the development of neurologic toxicity; however, it can...
Investigational
Matched Synonyms: … Anti-CD20/CD3 monoclonal antibody REGN1979 …
Matched Description: … [A254187] In December 2020, the FDA placed a partial clinical hold and requested the drug developer, ... Odronextamab is a hinge-stabilized, fully human immunoglobulin G4 (IgG4)-based CD20×CD3 bispecific antibody
Investigational
Matched Synonyms: … antibody-drug conjugate DP303c …
ATI-1013 is a fully human nicotine-specific monoclonal antibody.
Investigational
Matched Synonyms: … Fully human nicotine-specific monoclonal antibody
Matched Description: … ATI-1013 is a fully human nicotine-specific monoclonal antibody. …
HLX-58 is an investigational monoclonal antibody targeted against claudin 18.2.
Investigational
Matched Synonyms: … Recombinant anti-claudin 18.2 monoclonal antibody
Matched Description: … HLX-58 is an investigational monoclonal antibody targeted against claudin 18.2. …
Approved
Experimental
Matched Synonyms: … Golden seal ... Golden seal root ... Golden seal extract …
Matched Mixtures name: … Echinacea/golden Seal Cold Formula …
Labetuzumab is a humanized monoclonal antibody to carcinoembryonic antigen that inhibits tumor growth. It is used in radioimmunotherapy.
Investigational
Matched Synonyms: … Monoclonal antibody hMN-14 ... MN14 monoclonal antibody to carcinoembryonic antigen …
Matched Description: … Labetuzumab is a humanized monoclonal antibody to carcinoembryonic antigen that inhibits tumor growth …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Rubella virus vaccine is a live attenuated virus vaccine for active immunization against rubella (German measles) that is subcutaneously administered. It is prepared from RA 27/3 strain of live attenuated rubella virus. Rubella is a common childhood disease, caused by rubella virus (togavirus).
Approved
Investigational
Matched Synonyms: … Rubivirus rubella virus Wistar RA 27/3 whole
Matched Mixtures name: … MEASLES AND RUBELLA VIRUS VACCINE LIVE ... SII Measles and Rubella Virus Vaccine live.Attenuated(Freeze-Dried) 10 doses ... SII Measles and Rubella Virus Vaccine live.Attenuated(Freeze-Dried) 1 dose …
Matched Categories: … measles, combinations with mumps and rubella, live attenuated ... measles, combinations with mumps, rubella and varicella, live attenuated …
Oregovomab is a murine monoclonal antibody that attaches to the tumor-associated antigen CA125.
Investigational
Matched Synonyms: … Monoclonal antibody B43.13 …
Matched Description: … Oregovomab is a murine monoclonal antibody that attaches to the tumor-associated antigen CA125. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Approved
Experimental
Matched Synonyms: … Monoclonal antibody anti-SSEA-1 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Galiximab is a chimeric monoclonal antibody which is used as an immunosuppressive drug.
Investigational
Matched Synonyms: … Anti-CD80 monoclonal antibody
Matched Description: … Galiximab is a chimeric monoclonal antibody which is used as an immunosuppressive drug. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability. Citric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA...
Approved
Nutraceutical
Vet approved
Matched Synonyms: … 3-carboxy-3-hydroxypentane-1,5-dioic acid …
Matched Mixtures name: … Alka-Seltzer Gold ... Imuflex Wb-SP Blood Bag System With Integral Whole Blood Leukocyte Reduction Filter (saving Platelets ... IMUFLEX WB-SP Blood Bag System with Integral Whole Blood Leukocyte Reduction Filter (Saving Platelets …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Stop Hair …
Osteoarthritis (OA) is a progressive and degenerative joint disease marked by loss of cartilage, bone changes, and synovial membrane inflammation. Treatment with chondroprotective drugs, such as glucosamine sulfate may offer additional benefits to nonsteroidal anti-inflammatory drugs treating the painful symptoms of OA. Glucosamine is commonly used over the counter as...
Approved
Investigational
Matched Description: … changes, and synovial membrane inflammation. ... Osteoarthritis (OA) is a progressive and degenerative joint disease marked by loss of cartilage, bone ... for arthritic joint pain, although its acceptance as a medical therapy varies due to contradictory and
Matched Mixtures name: … Bee Venom Joint And Bone Therapy Drops ... Blackmores Joint Formula with Glucosamine and Chondroitin ... Gold Life® Joinflex Capsule …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … GOLD LIFE® JOINTRIL CAPSULE ... Gold Life® Jointril 500 Capsule …
Saw palmetto is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Investigational
Matched Categories: … Herbs and Natural Products …
Matched Products: … Quanterra Urinary Flow ... Ethical Herbals Urinary Flow
Investigational
Matched Synonyms: … 2-((2s)-2-methyl-1,4-dioxa-8-azaspiro(4.5)decan-8-yl)-8-nitro-6-trifluoromethyl-4h-1,3-benzothiazin-4 ... 4h-1,3-benzothiazin-4-one, 2-((2s)-2-methyl-1,4-dioxa-8-azaspiro(4.5)dec-8-yl)-8-nitro-6-(trifluoromethyl …
Matched Iupac: … 2-[(2S)-2-methyl-1,4-dioxa-8-azaspiro[4.5]decan-8-yl]-8-nitro-6-(trifluoromethyl)-4H-1,3-benzothiazin …
Experimental
Matched Name: … 2-(Oxalyl-Amino)-Benzoic Acid …
Retifanlimab is a humanized IgG4 kappa monoclonal antibody that binds to the programmed death receptor-1 (PD-1), blocking PD-1 interaction with its ligands, programmed death-ligand 1 (PD-L1) and programmed death-ligand 2 (PD-L2). By blocking the PD-1/PD-L1/2 pathway, retifanlimab potentiates T-cell activity and boosts the immune response against cancer cells. Other monoclonal...
Approved
Investigational
Matched Synonyms: … Anti-PD-1 monoclonal antibody MGA012 …
Matched Description: … -1 (PD-1), blocking PD-1 interaction with its ligands, programmed death-ligand 1 (PD-L1) and programmed ... By blocking the PD-1/PD-L1/2 pathway, retifanlimab potentiates T-cell activity and boosts the immune ... [L45603] Other monoclonal antibodies that block PD-1 include [pembrolizumab], [nivolumab] and [cemiplimab …
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Programmed Death Receptor-1 Blocking Antibody
Neuradiab is under investigation in clinical trial NCT00615186 (Glioblastoma Multiforme (GBM) Locoregional Agent Survival Study - Anti-tenascin Radiolabeled Antibody Therapy).
Investigational
Matched Synonyms: … Iodine i 131 monoclonal antibody 81c6 ... Iodine I-131 monoclonal antibody 81c6 ... Anti-tenascin monoclonal antibody 81c6-I-131 …
Matched Name: … Iodine I-131 monoclonal antibody 81C6 …
Matched Description: … NCT00615186 (Glioblastoma Multiforme (GBM) Locoregional Agent Survival Study - Anti-tenascin Radiolabeled Antibody
Pramocaine (also known as pramoxine or pramoxine HCI) is a topical anesthetic and antipruritic. It is used for many dermatological and anorectal/anogenital conditions including minor cuts/burns, insect bites, hives/rashes due to poison ivy exposure, hemorrhoids and other anorectal/anogenital disorders. Pramocaine is available by itself and in combination with other medications...
Approved
Matched Description: … It works by preventing ionic fluctuations needed for neuron membrane depolarization and action potential ... Pramocaine (also known as pramoxine or pramoxine HCI) is a topical anesthetic and antipruritic. ... It is used for many dermatological and anorectal/anogenital conditions including minor cuts/burns, insect …
Matched Mixtures name: … Gold Bond Anti Itch ... Gold Bond Anti Itch ... Gold Bond Anti-itch Lotion …
Matched Categories: … Antipruritics and Local Anesthetics ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … Gold Bond Intensive Healing Anti Itch Skin Protectant …
Displaying drugs 551 - 575 of 772 in total