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Displaying drugs 551 - 575 of 923 in total
Valsartan belongs to the angiotensin II receptor blocker (ARB) family of drugs, which also includes telmisartan, candesartan, losartan, olmesartan, and irbesartan. ARBs selectively bind to angiotensin receptor 1 (AT1) and prevent the protein angiotensin II from binding and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis of aldosterone...
Approved
Investigational
Matched Synonyms: … N-(P-(O-1H-Tetrazol-5-ylphenyl)benzyl)-N-valeryl-L-valine ... (S)-N-Valeryl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl}-valine ... N-pentanoyl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-L-valine
Matched Description: … [A174124] Valsartan is generally well-tolerated with a side-effect profile superior to that of other ... and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis of ... aldosterone and ADH, cardiac stimulation, and renal reabsorption of sodium, among others. …
Matched Mixtures name: … Valsartan and Hydrochlorothiazide ... Valsartan and Hydrochlorothiazide ... Valsartan and Hydrochlorothiazide …
Matched Categories: … Angiotensin II Antagonists and Diuretics ... Angiotensin II Antagonists and Calcium Channel Blockers ... valsartan and nebivolol ... Angiotensin II receptor blockers (ARBs) and diuretics ... valsartan and diuretics …
Experimental
Matched Name: … L-Threoninol
A naturally occurring amino acid in both eukaryotic and prokaryotic organisms. It is found in tRNAs and in the catalytic site of some enzymes. The genes for glutathione peroxidase and formate dehydrogenase contain the TGA codon, which codes for this amino acid. [PubChem]
Experimental
Matched Synonyms: … 3-selenyl-L-alanine
Matched Description: … A naturally occurring amino acid in both eukaryotic and prokaryotic organisms. ... It is found in tRNAs and in the catalytic site of some enzymes. ... The genes for glutathione peroxidase and formate dehydrogenase contain the TGA codon, which codes for …
Matched Categories: … Amino Acids, Peptides, and Proteins …
An amino acid analogue and antibiotic derived from the bacterium Streptomyces alanosinicus with antimetabolite and potential antineoplastic activities.
Investigational
Matched Synonyms: … Alanosine ... L-Alanosine
Matched Name: … Alanosine
Matched Description: … and potential antineoplastic activities. ... An amino acid analogue and antibiotic derived from the bacterium Streptomyces alanosinicus with antimetabolite …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Mecbotamab vedotin is an anti-Axl humanized monoclonal antibody conjugated to monomethyl auristatin E using a cleavable linker (CAB-Axl-ADC).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1 (DE-450-LYSINE), ANTI-(HUMAN TYROSINE KINASE RECEPTOR AXL) (HUMAN-MUS MUSCULUS MONOCLONAL …
Experimental
Matched Name: … N-[(CYCLOHEXYLAMINO)CARBONYL]GLYCINE
Experimental
Matched Name: … Tryptophanyl-5'amp …
An opioid analgesic chemically related to and with an action resembling that of meperidine, but more rapid in onset and of shorter duration. It has been used in obstetrics, as pre-operative medication, for minor surgical procedures, and for dental procedures. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1067)
Experimental
Illicit
Matched Synonyms: … beta-Prodine
Matched Description: … rapid in onset and of shorter duration. ... An opioid analgesic chemically related to and with an action resembling that of meperidine, but more ... It has been used in obstetrics, as pre-operative medication, for minor surgical procedures, and for dental …
Magnesium glycinate is a magnesium salt of glycine that is available as dietary supplements as a source of magnesium. It is used in the treatment of magnesium deficiency.
Approved
Matched Synonyms: … Magnesium glycinate
Matched Name: … Magnesium glycinate
Matched Description: … Magnesium glycinate is a magnesium salt of glycine that is available as dietary supplements as a source …
Experimental
Matched Synonyms: … N-Palmitoyl glycine ... N-(1-Oxohexadecyl)glycine
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Synonyms: … Tyramine sulfate …
Matched Name: … Tyramine O-sulfate …
Experimental
Matched Name: … Nz-(1-Carboxyethyl)-Lysine
Experimental
Matched Name: … 4-NITRO-BENZYLPHOSPHONOBUTANOYL-GLYCINE
Experimental
Matched Synonyms: … N-(3-Propylcarbamoyloxirane-2-carbonyl)-isoleucyl-proline
Matched Name: … N-(3-Propylcarbamoyloxirane-2-Carbonyl)-Isoleucyl-Proline
Matched Categories: … Amino Acids, Peptides, and Proteins …
Batoclimab is under investigation in clinical trial NCT04428255 (A Clinical Study on the Efficacy and Safety of HBM9161 in Patients With ITP).
Investigational
Matched Synonyms: … Immunoglobulin g1(238-alanine, 239-alanine), anti-(human fcrn receptor) (human monoclonal hl161bkn .gamma …
Matched Description: … Batoclimab is under investigation in clinical trial NCT04428255 (A Clinical Study on the Efficacy and
Matched Categories: … Amino Acids, Peptides, and Proteins …
HMI-102 is an investigational gene therapy designed to encode the phenylalanine-4-hydroxylase (PAH) gene, mutated in people with phenylketonuria.
Investigational
Matched Synonyms: … Recombinant adeno-associated viral vector serotype HSC expressing human phenylalanine hydroxylase …
Matched Description: … HMI-102 is an investigational gene therapy designed to encode the phenylalanine-4-hydroxylase (PAH) gene …
A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016). Procaine has also been investigated as an oral entry inhibitor in...
Approved
Investigational
Vet approved
Matched Synonyms: … Procaine
Matched Name: … Procaine
Matched Description: … A local anesthetic of the ester type that has a slow onset and a short duration of action. ... It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. ... Procaine has also been investigated as an oral entry inhibitor in treatment-experienced HIV patients …
Matched Salts name: … Procaine nitrate ... Procaine phosphate ... Procaine hydrochloride …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... procaine ... procaine ... procaine ... procaine, combinations …
Matched Products: … Procaine Hydrochloride …
Exebacase is under investigation in clinical trial NCT03163446 (Safety, Efficacy and Pharmacokinetics of CF-301 vs. Placebo in Addition to Antibacterial Therapy for Treatment of S. Aureus Bacteremia).
Investigational
Matched Synonyms: … Lysin cf-301 (streptococcus suis phage) ... Lysin plyss2 (streptococcus suis phage) ... Des-met1-putative phage lysin (streptococcus phage phi891591), produced in escherichia coli …
Matched Description: … Exebacase is under investigation in clinical trial NCT03163446 (Safety, Efficacy and Pharmacokinetics …
Matched Categories: … Enzymes and Coenzymes …
Experimental
Matched Synonyms: … 4-O-phosphono-L-threonic acid …
Matched Name: … 4-phospho-L-threonic acid …
Experimental
Matched Products: … LYSEEN
Elranatamab is a bispecific B-cell maturation antigen (BCMA)-directed CD3 T-cell engager. It is a humanized immunoglobulin 2-alanine kappa antibody derived from two monoclonal antibodies (mAbs), an anti-BCMA mAb and an anti-CD3 mAb, each of which contributes one heavy chain and one light chain to drug structure. The resulting 4-chain bispecific...
Approved
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G2 (224-ARGININE,265-ALANINE,330-SERINE,331-SERINE), ANTI-(HUMAN CD3 ANTIGEN .EPSILON. …
Matched Description: … ), an anti-BCMA mAb and an anti-CD3 mAb,[A261060] each of which contributes one heavy chain and one light ... It is a humanized immunoglobulin 2-alanine kappa antibody derived from two monoclonal antibodies (mAbs …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Tyramine (4-hydroxyphenethylamine; para-tyramine, mydrial or uteramin) is a naturally occurring monoamine compound and trace amine derived from the amino acid tyrosine. Tyramine acts by inducing the release of catecholamine. An important characteristic of this product is its impediment to cross the blood-brain barrier which restrains its side effects to only...
Investigational
Nutraceutical
Matched Name: … Tyramine
Matched Description: … compound and trace amine derived from the amino acid tyrosine. ... Tyramine (4-hydroxyphenethylamine; para-tyramine, mydrial or uteramin) is a naturally occurring monoamine ... Tyramine acts by inducing the release of catecholamine. …
Matched Salts name: … Tyramine hydrochloride …
Tyrosinase is a multi-copper-containing multifunctional metalloenzyme with 4 possible oxidation states.[A231829, A231834, A231839] It is responsible for producing melanin pigment across the phylogenetic spectrum.[A231829, A231834, A231839] Within mammals, tyrosinase is found specifically in melanocytes in a glycosylated form and plays a critical role in regulating the process of melanin biosynthesis...
Investigational
Matched Name: … Tyrosinase
Matched Description: … in mammals, thus causing undesired browning of fruits and vegetables and diseases resulting from melanin ... form and plays a critical role in regulating the process of melanin biosynthesis (also known as melanogenesis ... [A231829, A231839] It is recognized as being the main enzyme responsible for enzymatic browning and melanogenesis …
Matched Categories: … Enzymes and Coenzymes …
Experimental
Matched Synonyms: … 3-Nitro-L-tyrosine
Matched Name: … 3-nitro-L-tyrosine
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Synonyms: … L-tryptophan amide …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Displaying drugs 551 - 575 of 923 in total