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Displaying drugs 551 - 575 of 711 in total
Tomaralimab is under investigation in clinical trial NCT01794663 (Placebo-Controlled Study to Evaluate the Safety and Efficacy of OPN-305 in Preventing Delayed Renal Graft Function).
Investigational
Matched Synonyms: … anti-Tlr2 monoclonal antibody OPN-305 ... Humanized IGG4 monoclonal antibody against toll-like receptor 2 for prevention of ischemia/reperfusion …
Matched Description: … under investigation in clinical trial NCT01794663 (Placebo-Controlled Study to Evaluate the Safety and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Bexmarilimab is under investigation in clinical trial NCT03733990 (A Study to Evaluate Safety, Tolerability and Preliminary Efficacy of FP-1305 in Cancer Patients).
Investigational
Matched Synonyms: … Anti-clever-1 monoclonal antibody FP-1305 …
Matched Description: … Bexmarilimab is under investigation in clinical trial NCT03733990 (A Study to Evaluate Safety, Tolerability and
Matched Categories: … Amino Acids, Peptides, and Proteins …
A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed) Sodium lactate is the sodium salt of lactic acid, and has a mild saline taste. It is produced by fermentation of a sugar source, such as...
Approved
Vet approved
Matched Description: … (From Stedman, 26th ed) Sodium lactate is the sodium salt of lactic acid, and has a mild saline taste ... It is produced by fermentation of a sugar source, such as corn or beets, and then, by neutralizing the …
Matched Mixtures name: … Potassium Chloride and Dextrose ... Potassium Chloride in Lactated Ringers and Dextrose ... Potassium Chloride in Lactated Ringers and Dextrose …
Matched Categories: … Basic Ointments and Protectants ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … SODIO LATTATO GALENICA SENESE
CR002 is a novel investigational fully human monoclonal antibody that blocks the activity of excess platelet-derived growth factor-D (PDGF-D), a target shown to play a role in kidney inflammation. This is a novel therapeutic approach to treat kidney inflammation.
Investigational
Matched Synonyms: … Human monoclonal antibody against platelet-derived growth factor D …
Matched Description: … CR002 is a novel investigational fully human monoclonal antibody that blocks the activity of excess platelet-derived …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Simtuzumab has been used in trials studying the treatment and basic science of Myelofibrosis, Pancreatic Cancer, Colorectal Cancer, and Idiopathic Pulmonary Fibrosis.
Investigational
Matched Synonyms: … Recombinant humanized anti-LOXL2 monoclonal antibody
Matched Description: … Cancer, Colorectal Cancer, and Idiopathic Pulmonary Fibrosis. ... Simtuzumab has been used in trials studying the treatment and basic science of Myelofibrosis, Pancreatic …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Tetracycline is a broad spectrum polyketide antibiotic produced by the Streptomyces genus of Actinobacteria. It exerts a bacteriostatic effect on bacteria by binding reversible to the bacterial 30S ribosomal subunit and blocking incoming aminoacyl tRNA from binding to the ribosome acceptor site. It also binds to some extent to the...
Approved
Vet approved
Withdrawn
Matched Description: … exerts a bacteriostatic effect on bacteria by binding reversible to the bacterial 30S ribosomal subunit and ... It also binds to some extent to the bacterial 50S ribosomal subunit and may alter the cytoplasmic membrane …
Matched Mixtures name: … Bismuth Subcitrate Potassium, Metronidazole and Tetracycline Hydrochloride ... Bismuth Subcitrate Potassium, Metronidazole, and Tetracycline Hydrochloride ... Bismuth subcitrate potassium, Metronidazole, Tetracycline hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... tetracycline and oleandomycin ... Ophthalmological and Otological Preparations ... lansoprazole, tetracycline and metronidazole ... Antiinfectives and Antiseptics for Local Oral Treatment …
Matched Products: … MeaStem First Aid and Antibiotic …
SAR-439459 is a pan-transforming Growth Factor-beta (TGFβ) neutralizing antibody. Developed by Sanofi, it is being investigated for the treatment of cancers and Osteogenesis Imperfecta.
Investigational
Matched Synonyms: … ANTI-TGF-BETA MONOCLONAL ANTIBODY SAR-439459 …
Matched Description: … [A259862] Developed by Sanofi, it is being investigated for the treatment of cancers and Osteogenesis ... SAR-439459 is a pan-transforming Growth Factor-beta (TGFβ) neutralizing antibody. …
RC118 is an antibody-drug conjugate that consists of a recombinant humanized IgG1 anti-Claudin18.2 monoclonal antibody conjugated to MMAE.
Investigational
Matched Synonyms: … Recombinant humanized anti-MSLN monoclonal antibody- monomethyl auristatin E conjugate …
Matched Description: … antibody conjugated to MMAE. ... RC118 is an antibody-drug conjugate that consists of a recombinant humanized IgG1 anti-Claudin18.2 monoclonal …
Sonelokimab is under investigation in clinical trial NCT06411379 (Study to Evaluate the Efficacy and Safety of Subcutaneous Sonelokimab Compared With Placebo in Adult Participants With Moderate to Severe Hidradenitis Suppurativa).
Investigational
Matched Synonyms: … M-1095 (anti-interleukin (il)-17a/f single-domain antibody) …
Matched Description: … Sonelokimab is under investigation in clinical trial NCT06411379 (Study to Evaluate the Efficacy and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Anetumab ravtansine is under investigation in clinical trial NCT03455556 (Anetumab Ravtansine and Atezolizumab in Treating Participants With Advanced Non-small Cell Lung Cancer).
Investigational
Matched Synonyms: … Anti-mesothelin antibody-drug conjugate BAY 94-9343 …
Matched Description: … Anetumab ravtansine is under investigation in clinical trial NCT03455556 (Anetumab Ravtansine and Atezolizumab …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antibody-drug Conjugates …
CMG901 is an anti-Claudin 18.2 monoclonal antibody conjugated with MMAE payload.
Investigational
Matched Synonyms: … an anti-Claudin 18.2 monoclonal antibody conjugated with MMAE payload …
Matched Description: … CMG901 is an anti-Claudin 18.2 monoclonal antibody conjugated with MMAE payload. …
Bazlitoran is under investigation in clinical trial NCT02092909 (Phase 1/2 Dose Escalation Study in Patients With Relapsed or Refractory Waldenstrom's Macroglobulinemia).
Investigational
Matched Synonyms: … Antagonist of the endosomal Toll-like receptors (TLRs) 7, 8, and 9 …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Coltuximab ravtansine (SAR3419) targets CD19 and is being investigated for the treatment of acute lymphoblastic leukemia (ALL).
Investigational
Matched Synonyms: … Anti-CD19 humanized monoclonal antibody conjugated to DM4 …
Matched Description: … Coltuximab ravtansine (SAR3419) targets CD19 and is being investigated for the treatment of acute lymphoblastic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antibody-drug Conjugates …
Investigational
Matched Synonyms: … Recombinant human monoclonal IgM antibody targeting glucose regulated protein 78 …
Ertumaxomab is under investigation in clinical trial NCT00522457 (Phase II Study With the Trifunctional Antibody Ertumaxomab to Treat Metastatic Breast Cancer After Progression on Trastuzumab Therapy).
Investigational
Matched Synonyms: … Anti-cd3 x anti-her-2-neu bispecific monoclonal antibody
Matched Description: … Ertumaxomab is under investigation in clinical trial NCT00522457 (Phase II Study With the Trifunctional Antibody
Matched Categories: … Amino Acids, Peptides, and Proteins …
Ontamalimab is under investigation in clinical trial NCT03627091 (Efficacy and Safety Study of SHP647 as Maintenance Treatment in Participants With Moderate to Severe Crohn's Disease (CARMEN CD 307)).
Investigational
Matched Synonyms: … human IgG2 monoclonal antibody directed against the mucosal addressin cell adhesion molecule ... human IgG2 anti-monoclonal antibody directed against mucosal addressin cell adhesion molecule (MAdCAM …
Matched Description: … Ontamalimab is under investigation in clinical trial NCT03627091 (Efficacy and Safety Study of SHP647 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
A non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter.
Approved
Nutraceutical
Vet approved
Matched Description: … It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... NUTRIPLUS LIPID SENZA ELETTROLITI …
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... Blood Substitutes and Perfusion Solutions …
Matched Products: … GLICINA GALENICA SENESE
Calcium chloride is an ionic compound of calcium and chlorine. It is highly soluble in water and it is deliquescent. It is a salt that is solid at room temperature, and it behaves as a typical ionic halide. It has several common applications such as brine for refrigeration plants, ice...
Approved
Matched Description: … It is a salt that is solid at room temperature, and it behaves as a typical ionic halide. ... , and in cement. ... It is highly soluble in water and it is deliquescent. …
Matched Mixtures name: … Potassium Chloride and Dextrose ... Potassium Chloride in Lactated Ringers and Dextrose ... Potassium Chloride in Lactated Ringers and Dextrose …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... ascorbic acid (vit C) and calcium ... Blood Substitutes and Perfusion Solutions ... Genito Urinary System and Sex Hormones …
Matched Products: … CALCIO CLORURO GALENICA SENESE
Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID).[label] NSAIDs inhibit cyclooxygenase (COX)-1 and-2 which are the enzyme responsible for producing prostaglandins (PGs). PGs contribute to inflammation and pain signalling. Diclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation...
Approved
Vet approved
Matched Description: … Diclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation ... PGs contribute to inflammation and pain signalling. ... Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID). …
Matched Mixtures name: … Diclofenac Sodium and Misoprostol ... Diclofenac Sodium and Misoprostol ... Diclofenac Sodium and Misoprostol …
Matched Salts name: … Diclofenac potassium
Matched Categories: … Acetic Acid Derivatives and Related Substances ... diclofenac and antiinfectives ... Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Up and Up Arthritis Pain Reliever ... Diclofenac Potassium ... DICLOFENAC POTASSIUM
Satralizumab is a recombinant humanized monoclonal antibody targeted against human interleukin-6 (IL-6) receptors, similar to tocilizumab, which is produced in Chinese hamster ovary cells and based on an IgG2 framework. Satralizumab is used in the treatment of neuromyelitis optica spectrum disorder (NMOSD), a rare autoimmune inflammatory disorder of the central...
Approved
Matched Synonyms: … Humanised anti-IL-6 receptor monoclonal antibody
Matched Description: … Satralizumab is a recombinant humanized monoclonal antibody targeted against human interleukin-6 (IL- ... [A218551] It received subsequent approvals in Switzerland and Japan,[A218551] and was approved for use ... formulated with "recycling antibody technology" whereby the association of satralizumab to IL-6 receptors …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
A166 is an antibody-drug conjugate composed of a novel cytotoxic drug (Duo-5, anti-microtubule agent) site-specifically conjugated to an anti-HER2 antibody (trastuzumab) via a stable protease-cleavable valine citrulline linker.
Investigational
Matched Synonyms: … Recombinant humanized IgG1 anti-HER2 monoclonal antibody conjugated to Duostatin-5 …
Matched Description: … A166 is an antibody-drug conjugate composed of a novel cytotoxic drug (Duo-5, anti-microtubule agent) ... site-specifically conjugated to an anti-HER2 antibody (trastuzumab) via a stable protease-cleavable …
Carlumab has been used in trials studying the treatment of Cancer and Prostate Cancer.
Investigational
Withdrawn
Matched Synonyms: … Human monoclonal antibody targeting CC-chemokine ligand 2 (CNTO 888) …
Matched Description: … Carlumab has been used in trials studying the treatment of Cancer and Prostate Cancer. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
AOC 1001 is an antibody oligonucleotide conjugate (AOC), comprised of a human transferrin receptor 1 (TfR1) targeting, effector function null, humanized IgG1 antibody (AV01mAb) conjugated to one small interfering RNA (siRNA).
Investigational
Matched Synonyms: … an antibody oligonucleotide conjugate (AOC), comprised of a human transferrin receptor 1 (TfR1) targeting ... , effector function null, humanized IgG1 antibody (AV01mAb) conjugated to one small interfering RNA ( …
Matched Description: … AOC 1001 is an antibody oligonucleotide conjugate (AOC), comprised of a human transferrin receptor 1 ... (TfR1) targeting, effector function null, humanized IgG1 antibody (AV01mAb) conjugated to one small interfering …
SBT-100 is an anti-signal transducer and activator of transcription 3 (STAT3) B VHH13 single-domain antibody (sdAb). It was granted orphan drug designation by the FDA for the treatment of pancreatic cancer and osteosarcoma.[L44131,L44136]
Investigational
Matched Synonyms: … Anti-STAT3 B VHH13 single domain antibody
Matched Description: … SBT-100 is an anti-signal transducer and activator of transcription 3 (STAT3) B VHH13 single-domain antibody ... It was granted orphan drug designation by the FDA for the treatment of pancreatic cancer and osteosarcoma …
RLYB212 is a human monoclonal antibody against Antigen-1A Immunoglobulin (HPA-1A). It is currently being developed by Rallybio for the prevention of fetal and neonatal alloimmune thrombocytopenia.
Investigational
Matched Synonyms: … Recombinant human IgG monoclonal HPA-1a antibody
Matched Description: … It is currently being developed by Rallybio for the prevention of fetal and neonatal alloimmune thrombocytopenia ... RLYB212 is a human monoclonal antibody against Antigen-1A Immunoglobulin (HPA-1A). …
Displaying drugs 551 - 575 of 711 in total