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Displaying drugs 551 - 575 of 676 in total
Zolmitriptan is a member of the triptan class of 5-hydroxytryptamine(5-HT)1B/1D/(1F) receptor agonists used to treat acute migraine.[A462, L12978] Sumatriptan was the first triptan to be developed, but had poor oral bioavailability and lipophilicity. This led to the development of second-generation triptans, including almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, and zolmitriptan. Triptans...
Approved
Investigational
Matched Description: … the current "gold standard" for acute migraine treatment. ... It is currently available in both tablet and nasal spray forms.[L12978] ... A462, L12978] [Sumatriptan] was the first triptan to be developed, but had poor oral bioavailability and
Matched Categories: … Serotonin-1b and Serotonin-1d Receptor Agonist …
Matched Products: … Septa-zolmitriptan-odt …
Rivoceranib is under investigation in clinical trial NCT02726854 (Apatinib as Second-line Treatment of Advanced Pancreatic Cancer).
Investigational
Matched Synonyms: … YN968D1 free base
Nevanimibe is under investigation in clinical trial NCT03053271 (A Study of ATR-101 for the Treatment of Endogenous Cushing's Syndrome).
Investigational
Matched Synonyms: … Atr-101 free base
Revaprazan is under investigation in clinical trial NCT01750437 (Phase 2 Clinical Trial to Investigate the Safety, Tolerability and Efficacy of YH1885L in Patients With Non-erosive Reflux Disease(nerd)).
Investigational
Matched Synonyms: … Yh-1885 free base
Matched Description: … investigation in clinical trial NCT01750437 (Phase 2 Clinical Trial to Investigate the Safety, Tolerability and
Investigational
Matched Synonyms: … BMS-833923 free base anhydrous …
Queuine is a derivative of 7-Deazaguanine. Bacteria possess the exclusive ability to synthesize queuine, which is then salvaged and passed on to plants and animals. Quantities of queuine have been found in tomatoes, wheat, coconut water, and milk from humans, cows, and goats. Humans salvage and recover queuine from either...
Experimental
Nutraceutical
Matched Synonyms: … Base Q ... Q Base
Matched Description: … plants and animals. ... and goats. ... Bacteria possess the exclusive ability to synthesize queuine, which is then salvaged and passed on to …
Candesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. It is available as a prodrug in the form of candesartan cilexetil.
Experimental
Matched Categories: … candesartan and diuretics ... Angiotensin II receptor blockers (ARBs) and diuretics ... candesartan and amlodipine ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers ... atorvastatin, amlodipine and candesartan …
Matched Products: … CANDESARTAN BASICS 4MG ... CANDESARTAN BASICS 8MG ... CANDESARTAN BASICS 16MG …
Investigational
Matched Synonyms: … Human monoclonal antibody based on an IgG1 lambda framework against human interferon gamma …
A plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic and in the treatment of impotence. It is also alleged to be an aphrodisiac.
Approved
Investigational
Vet approved
Matched International brands: … Baron-X …
Matched Description: … Yohimbine has been used as a mydriatic and in the treatment of impotence. …
Matched Categories: … Genito Urinary System and Sex Hormones …
An antagonist of nociceptin receptor and analgesic agent, evaluated for its use in cancer treatment.
Investigational
Matched Name: … JTC-801 free base
Matched Description: … An antagonist of nociceptin receptor and analgesic agent, evaluated for its use in cancer treatment. …
Investigational
Matched Synonyms: … AQ-13 free base
Matched Name: … AQ-13 free base
Experimental
Investigational
Matched Name: … K201 free base
Melaleuca quinquenervia pollen is the pollen of the Melaleuca quinquenervia plant. Melaleuca quinquenervia pollen is mainly used in allergenic testing.
Approved
Matched Synonyms: … Broad leaved paperbark pollen extract …
First synthesized by Janssen Pharmaceuticals in 1955, cinnarizine is an anti-histaminic drug mainly used for the control of vestibular disorders and motion sickness. Cinnarizine is a specific calcium channel blocker that primarily works on the central vestibular system to interfere with the signal transmission between vestibular apparatus of the inner...
Approved
Investigational
Matched International brands: … Sepan
Matched Description: … in 1955, cinnarizine is an anti-histaminic drug mainly used for the control of vestibular disorders and ... vestibular system to interfere with the signal transmission between vestibular apparatus of the inner ear and
Matched Categories: … Calcium-Regulating Hormones and Agents …
Aprotinin is a protein-based drug that is also known as bovine pancreatic trypsin inhibitor (BPTI). Since it demonstrates the capacity to slow fibrinolysis, it has been employed to reduce bleeding during complex surgery such as heart and liver surgery. For this use, it is typically administered by injection. The goal...
Approved
Investigational
Withdrawn
Matched Synonyms: … Trypsin inhibitor, pancreatic basic
Matched Description: … to slow fibrinolysis, it has been employed to reduce bleeding during complex surgery such as heart and ... was subsequently to minimize end-organ damage resulting from hypotension due to blood loss in surgery and ... Aprotinin is a protein-based drug that is also known as bovine pancreatic trypsin inhibitor (BPTI). …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Ketoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal infections.[FDA Label] It functions by preventing the synthesis of ergosterol, the fungal equivalent of cholesterol, thereby increasing membrane fluidity and preventing growth of the fungus.[A181802,T116] Ketoconazole was first approved in an oral formulation...
Approved
Investigational
Matched Description: … Ketoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal ... [clotrimazole], due to its broad spectrum and good absorption. ... synthesis of ergosterol, the fungal equivalent of cholesterol, thereby increasing membrane fluidity and
Matched Mixtures name: … SPORUM-D …
Matched Categories: … Sex Hormones and Insulins ... Imidazole and Triazole Derivatives ... Gynecological Antiinfectives and Antiseptics ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … SPOREX ... SPORUM® CASP 2% CHAMPU …
Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability out of all of the...
Approved
Nutraceutical
Vet approved
Matched Description: … d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and ... At the moment however, there exists a lack of formal data and evidence to support any such additional ... This biologic action of vitamin E consequently continues to generate ongoing interest and study in whether …
Matched Mixtures name: … Multi Vitamin and Mineral vitamin ... Iron With Vitamins C and E - Tab ... Vita Vim Multivitamins and Minerals Tab …
Matched Categories: … Diet, Food, and Nutrition …
Matched Products: … Clear Base E 800iu Cap ... CLEAR BASE VITAMIN E 400 IU CAPSULE …
Experimental
Matched Synonyms: … Golden shower fruit ... Golden shower tree fruit ... Golden shower cassia fruit …
SEP-363856 is a novel psychotropic drug being investigated for the treatment of schizophrenia. Unlike other drugs used for this condition, SEP-363856 does not bind to the dopamine D2 receptors, but exerts actions on the trace amine–associated receptor 1 (TAAR1) and 5-hydroxytryptamine type 1A (5-HT1A). SEP-363856 was developed by Sunovion pharmaceuticals....
Investigational
Matched Name: … SEP-363856 …
Matched Description: … Additional clinical trials of SEP-363856 are required to confirm the safety and efficacy of this drug ... , and social withdrawal. ... exerts actions on the trace amine–associated receptor 1 (TAAR1) and 5-hydroxytryptamine type 1A (5-HT1A …
SKF-96365 is a receptor-mediated calcium entry (RMCE) inhibitor structurally different from other calcium antagonists.
Investigational
Matched Name: … SKF-96365 free base
Matched Categories: … Calcium-Regulating Hormones and Agents …
JZP-386 is a deuterium-containing analog of sodium oxybate. Its safety, pharmacokinetics and pharmacodynamics were evaluated in clinical trial NCT02215499.
Investigational
Matched Name: … JZP-386 free base
Matched Description: … Its safety, pharmacokinetics and pharmacodynamics were evaluated in clinical trial NCT02215499. …
Investigational
Matched Synonyms: … Im156 free base ... Hl156a free base ... Hl-156a free base
Matched Name: … IM-156 free base
Investigational
Matched Name: … CPP-115 free base
Matched Categories: … Amino Acids, Peptides, and Proteins …
Pimagedine has been developed by Synvista Therapeutics, Inc for the treatment of diabetic kidney disease. It is an advanced glycation end product inhibitor which manages diabetic nephropathy, either alone or in combination with other therapies. It is beneficial in treating patients with diabetic nephropathy.
Investigational
Matched Synonyms: … Aminate base
Avobenzone is dibenzoyl methane derivative. It is oil soluble ingredient. Avobenzone has the ability to absorb ultraviolet light over wider range of wavelengths. It is included in many commercially available sunscreens which are used as wide spectrum sunscreens. Avobenzone is very sensitive to light, to increase its stability and duration...
Approved
Investigational
Matched Description: … Avobenzone is very sensitive to light, to increase its stability and duration of action, photostablizers ... sun, using sunscreen agents may help reduce long-term sun damage such as premature aging of the skin and
Matched Mixtures name: … Aveeno ABSOLUTELY AGELESS leave-on day mask Broad Spectrum SPF 30 ... Desert Fusion Nutritious Olive Leaf Daily Defense Broad Spectrum SPF 15 Sunscreen ... Aveeno ACTIVE NATURALS absolutely ageless leave-on day mask Broad Spectrum SPF30 …
Matched Products: … Naked Sundays Golden Glow Body Sunscreen SPF50 100ml …
Displaying drugs 551 - 575 of 676 in total