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Displaying drugs 5901 - 5925 of 7109 in total
Bizelesin has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific.
Investigational
Matched Iupac: … -5-yl})urea ... 1,3-bis({2-[(1S)-1-(chloromethyl)-5-hydroxy-8-methyl-1H,2H,3H,6H-pyrrolo[3,2-e]indole-3-carbonyl]-1H-indol …
Triciribine has been used in trials studying the treatment of Leukemia, Ovarian Cancer, HER2/Neu Negative, Breast Adenocarcinoma, and Stage IV Breast Cancer, among others.
Investigational
Matched Iupac: … (2R,3R,4S,5R)-2-{5-amino-7-methyl-2,6,7,9,11-pentaazatricyclo[6.3.1.0^{4,12}]dodeca-1(12),3,5,8,10-pentaen ... -2-yl}-5-(hydroxymethyl)oxolane-3,4-diol …
LTX-109 has been investigated for the treatment of Atopic Dermatitis, Mild Eczema/Dermatoses, and Gram-positive, Skin Infections.
Investigational
Matched Iupac: … ]-5-carbamimidamido-N-(2-phenylethyl)pentanamide ... (2S)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-(2,5,7-tri-tert-butyl-1H-indol-3-yl)propanamido …
Pimodivir is under investigation in clinical trial NCT02658825 (A Study to Evaluate the Effect of JNJ-63623872 on Cardiac Repolarization Interval in Healthy Participants).
Investigational
Matched Iupac: … (2S,3S)-3-[(5-fluoro-2-{5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl}pyrimidin-4-yl)amino]bicyclo[2.2.2]octane …
Rogaratinib is under investigation in clinical trial NCT03762122 (Rogaratinib in Patients With Advanced Pretreated Squamous-cell Non-small Cell Lung Cancer (SQCLC)).
Investigational
Matched Iupac: … 4-{[4-amino-5-(7-methoxy-5-methyl-1-benzothiophen-2-yl)-6-(methoxymethyl)pyrrolo[2,1-f][1,2,4]triazin ... -7-yl]methyl}piperazin-2-one …
Leptazoline B is a polar oxazoline from the Cyanobacterium Leptolyngbya sp. Also see Leptazoline A, Leptazoline C, and Leptazoline D.
Experimental
Matched Iupac: … (2S,3S)-3-[(4S,5S)-2-(5-chloro-2-hydroxyphenyl)-5-methyl-4,5-dihydro-1,3-oxazol-4-yl]-N-(1,3-dihydroxypropan …
Vecabrutinib is under investigation in clinical trial NCT03037645 (Safety, PK, PD, and Antitumor Activity of Vecabrutinib (SNS-062) in B Lymphoid Cancers).
Investigational
Matched Iupac: … (3R,3'R,4'S)-1'-(6-amino-5-fluoropyrimidin-4-yl)-3-{[3-chloro-5-(trifluoromethyl)phenyl]amino}-2-oxo- …
Matched Salts cas: … 1947403-49-7
Investigational
Matched Iupac: … N2-(4-cyclopropyl-5-fluoro-6-methylpyridin-2-yl)-N4-(1,5-dimethyl-1H-pyrazol-3-yl)-5-[(3R)-3,4-dimethylpiperazin …
Experimental
Illicit
Matched Iupac: … 4-methyl-5-phenyl-4,5-dihydro-1,3-oxazol-2-amine …
Experimental
Matched Iupac: … (2S)-5-carbamimidamido-2-(2-oxoazetidin-1-yl)pentanoic acid …
Experimental
Matched Iupac: … {[(2R,3S,4S)-2,3,4,6-tetrahydroxy-5-oxohexyl]oxy}phosphonic acid …
Investigational
Matched Iupac: … 5-methyl-2-(piperazin-1-yl)benzene-1-sulfonic acid …
Carmofur is a derivative of fluorouracil, and is an antineoplastic agent that has been used in the treatment of breast and colorectal cancer. Carmofur has been known to induce leukoencephalopathy.
Withdrawn
Matched Iupac: … 5-fluoro-N-hexyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-1-carboxamide …
Robenacoxib is a non-steroidal anti-inflammatory drug used in veterinary medicine for the relief of pain and inflammation in cats and dogs.
Experimental
Vet approved
Matched Iupac: … 2-{5-ethyl-2-[(2,3,5,6-tetrafluorophenyl)amino]phenyl}acetic acid …
Nimorazole has been used in trials studying the treatment of Hypoxia, Radiotherapy, Hypoxic Modification, Gene Profile, Gene Signature, and Head and Neck Squamous Cell Carcinoma, among others.
Investigational
Matched Iupac: … 4-[2-(5-nitro-1H-imidazol-1-yl)ethyl]morpholine …
Combretastatin has been investigated for the treatment of Anaplastic Thyroid Cancer.
Investigational
Matched Iupac: … 5-[(2R)-2-hydroxy-2-(3,4,5-trimethoxyphenyl)ethyl]-2-methoxyphenol …
Experimental
Matched Iupac: … 4-amino-N-(5-methylpyrimidin-2-yl)benzene-1-sulfonamide …
Experimental
Matched Iupac: … methyl N-(5-cyclopropanecarbonyl-1H-1,3-benzodiazol-2-yl)carbamate …
Experimental
Matched Iupac: … N-(5-nitro-1,3-thiazol-2-yl)thiophene-2-carboxamide …
Experimental
Matched Iupac: … [(2R,3S,4S,5S)-3,4-dihydroxy-5-(hydroxymethyl)-5-{[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl …
FF-10101-01 is under investigation in clinical trial NCT03194685 (Study of FF-10101-01 in Patients With Relapsed or Refractory Acute Myeloid Leukemia).
Investigational
Matched Iupac: … (2E)-N-[(1S)-1-[(5-{2-[(4-cyanophenyl)amino]-4-(propylamino)pyrimidin-5-yl}pent-4-yn-1-yl)carbamoyl]ethyl …
Experimental
Matched Iupac: … 2-{2-[(1S)-1-amino-2-(1H-imidazol-5-yl)ethyl]-5-hydroxy-4-[(4-oxocyclohexa-2,5-dien-1-ylidene)methyl] …
Radezolid has been used in trials studying the treatment of Abscess, Bacterial Skin Diseases, Streptococcal Infections, Infectious Skin Diseases, and Staphylococcal Skin Infections, among others.
Investigational
Matched Iupac: … -oxazolidin-5-yl]methyl}acetamide ... N-{[(5S)-3-[2-fluoro-4'-({[(1H-1,2,3-triazol-5-yl)methyl]amino}methyl)-[1,1'-biphenyl]-4-yl]-2-oxo-1,3 …
Matched Salts cas: … 869884-77-5
BMS-986158 is under investigation in clinical trial NCT02419417 (Study of BMS-986158 in Subjects With Select Advanced Cancers).
Investigational
Matched Iupac: … 2-[3-(1,4-dimethyl-1H-1,2,3-triazol-5-yl)-5-[(S)-(oxan-4-yl)(phenyl)methyl]-5H-pyrido[3,2-b]indol-7-yl …
Displaying drugs 5901 - 5925 of 7109 in total