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Displaying drugs 5926 - 5950 of 6316 in total

XAV-19

XAV-19 is an intravenous antibody-based treatment targeted towards SARS-CoV-2 and other coronaviruses[L16553,L16558]. The therapy concept is based on COVID-19 convalescent plasma. However, rather than using human plasma, XAV-19 is a heterologous swine glyco-humanized polyclonal antibody that targets the spike protein of SARS-CoV-2[L16553,L16558]. The therapy offers three beneficial effects: the ability...
Investigational
Matched Description: … As of July, 2020, the company is conducting a Phase 2 randomized clinical trial to define dosing safety ... The therapy offers three beneficial effects: the ability to neutralize the virus, reduce inflammatory ... that targets the spike protein of SARS-CoV-2[L16553,L16558]. …

Anti-SARS-CoV-2 IgY

Anti-SARS-CoV-2 IgY are chicken egg antibodies to SARS-CoV-2 which have the potential to provide temporary protection against the virus when administered as intranasal drops. To create these antibodies, chickens are injected in the chest with the spike protein, which is the surface protein of SARS-CoV-2; this results in an immune...
Investigational
Matched Synonyms: … Anti-Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Chicken Egg Antibody (IgY) …
Matched Name: … Anti-SARS-CoV-2 IgY …
Matched Description: … protection against the virus when administered as intranasal drops. ... Anti-SARS-CoV-2 IgY are chicken egg antibodies to SARS-CoV-2 which have the potential to provide temporary ... (SARS-CoV-2) Chicken Egg Antibody (IgY) (COVID-19)). …

PF-07304814

PF-07304814 is a small molecule prodrug that targets the 3CLpro protease (Mpro), which is used by viruses like SARS-CoV-2 to assemble and multiply . Once administered through intravenous infusion, the compound is cleaved into PF-00835231 to exert its anti-viral effects . PF-07304814, developed by Pfizer, was first identified during the...
Investigational
Matched Iupac: … [(3S)-3-[(2S)-2-[(4-methoxy-1H-indol-2-yl)formamido]-4-methylpentanamido]-2-oxo-4-[(3S)-2-oxopyrrolidin ... -3-yl]butoxy]phosphonic acid …
Matched Description: … Now, it is being tested regarding the novel SARS-CoV-2 virus, including studies in conjunction with [ ... PF-07304814 is a small molecule prodrug that targets the 3CLpro protease (Mpro) ... , which is used by viruses like SARS-CoV-2 to assemble and multiply[L31718]. …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …

N-Acetylmethionine

Experimental
Matched Synonyms: … (2S)-2-acetamido-4-(methylsulfanyl)butanoic acid ... N-Ac-Met ... L-(N-Acetyl)methionine …
Matched Name: … N-Acetylmethionine …
Matched Iupac: … (2S)-2-acetamido-4-(methylsulfanyl)butanoic acid …

Alminoprofen

Alminoprofen is a non-steroidal anti-inflammatory drug (NSAID) whose physiochemical characteristics make it a member of the phenylpropionic acid class of chemical substances.
Experimental
Matched Synonyms: … 2-{4-[(2-methylprop-2-en-1-yl)amino]phenyl}propionic acid ... α-methyl-4-[(2-methyl-2-propenyl)amino]benzeneacetic acid ... p-((2-Methylallyl)amino)hydratropic acid …
Matched Iupac: … 2-{4-[(2-methylprop-2-en-1-yl)amino]phenyl}propanoic acid …
Matched Description: … it a member of the phenylpropionic acid class of chemical substances. ... Alminoprofen is a non-steroidal anti-inflammatory drug (NSAID) whose physiochemical characteristics make …
Matched Categories: … Non COX-2 selective NSAIDS …

Volrubigene ralaparvovec

Volrubigene ralaparvovec is under investigation in clinical trial NCT03223194 (Gene Transfer Clinical Study in Crigler-najjar Syndrome).
Investigational

Cavrotolimod

Investigational
Matched Synonyms: … -OCTADECAOXA-57-AZA-19,39-DIPHOSPHAOCTAPENTACONT-1-YL HYDR ... DNA, D(P-THIO)(T-C-G-T-C-G-T-T-T-T-G-T-C-G-T-T-T-T-G-T-C-G-T-T), 3'-(58-((3.BETA.) ... -CHOLEST-5-EN-3-YLOXY)-19,39,42-TRIHYDROXY-19,39-DIOXIDO-58-OXO-3,6,9,12,15,18,20,23,26,29,32,35,38,40,44,47,50,53 …

2-(acetylamino)-2-deoxy-4-O-beta-D-galactopyranosyl-alpha-D-glucopyranose

Experimental
Matched Name: … 2-(acetylamino)-2-deoxy-4-O-beta-D-galactopyranosyl-alpha-D-glucopyranose …
Matched Iupac: … )oxan-2-yl]oxy}oxan-3-yl]acetamide ... N-[(2S,3R,4R,5S,6R)-2,4-dihydroxy-6-(hydroxymethyl)-5-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl …

Imino[2-(2-oxo-1,2-dihydro-3-pyridinyl)-1H-benzimidazol-5-yl]methanaminium

Experimental
Matched Name: … Imino[2-(2-oxo-1,2-dihydro-3-pyridinyl)-1H-benzimidazol-5-yl]methanaminium …
Matched Iupac: … {amino[2-(2-oxo-1,2-dihydropyridin-3-yl)-1H-1,3-benzodiazol-5-yl]methylidene}azanium …

4-chloro-N'-[(1E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide

Experimental
Matched Name: … 4-chloro-N'-[(1E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide …
Matched Iupac: … 4-chloro-N'-[(E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide …

2-(1,3-benzodioxol-5-yl)-5-[(3-fluoro-4-methoxybenzyl)sulfanyl]-1,3,4-oxadiazole

Experimental
Matched Name: … 2-(1,3-benzodioxol-5-yl)-5-[(3-fluoro-4-methoxybenzyl)sulfanyl]-1,3,4-oxadiazole …
Matched Iupac: … 2-(2H-1,3-benzodioxol-5-yl)-5-{[(3-fluoro-4-methoxyphenyl)methyl]sulfanyl}-1,3,4-oxadiazole …

3-Hydroxypropyl 3-[(7-carbamimidoyl-1-naphthyl)carbamoyl]benzenesulfonate

Experimental
Matched Name: … 3-Hydroxypropyl 3-[(7-carbamimidoyl-1-naphthyl)carbamoyl]benzenesulfonate …
Matched Iupac: … N-(7-carbamimidoylnaphthalen-1-yl)-3-[(3-hydroxypropoxy)sulfonyl]benzamide …

1-(2-DEOXY-5-O-PHOSPHONO-BETA-D-ERYTHRO-PENTOFURANOSYL)-4-METHYL-1H-INDOLE

Experimental
Matched Name: … 1-(2-DEOXY-5-O-PHOSPHONO-BETA-D-ERYTHRO-PENTOFURANOSYL)-4-METHYL-1H-INDOLE …
Matched Iupac: … {[(2R,3S,5R)-3-hydroxy-5-(4-methyl-1H-indol-1-yl)oxolan-2-yl]methoxy}phosphonic acid …

N-({(2S,3S)-3-[(BENZYLAMINO)CARBONYL]OXIRAN-2-YL}CARBONYL)-L-ISOLEUCYL-L-PROLINE

Experimental
Matched Name: … N-({(2S,3S)-3-[(BENZYLAMINO)CARBONYL]OXIRAN-2-YL}CARBONYL)-L-ISOLEUCYL-L-PROLINE …
Matched Iupac: … (2S)-1-[(2S,3S)-2-{[(2S,3S)-3-(benzylcarbamoyl)oxiran-2-yl]formamido}-3-methylpentanoyl]pyrrolidine-2 …

7-(aminomethyl)-6-(2-chlorophenyl)-1-methyl-1H-benzimidazole-5-carbonitrile

Experimental
Matched Name: … 7-(aminomethyl)-6-(2-chlorophenyl)-1-methyl-1H-benzimidazole-5-carbonitrile …
Matched Iupac: … 7-(aminomethyl)-6-(2-chlorophenyl)-1-methyl-1H-1,3-benzodiazole-5-carbonitrile …

N-[4-(2,4-DIMETHYL-THIAZOL-5-YL)-PYRIMIDIN-2-YL]-N',N'-DIMETHYL-BENZENE-1,4-DIAMINE

Experimental
Matched Name: … N-[4-(2,4-DIMETHYL-THIAZOL-5-YL)-PYRIMIDIN-2-YL]-N',N'-DIMETHYL-BENZENE-1,4-DIAMINE …
Matched Iupac: … N4-[4-(2,4-dimethyl-1,3-thiazol-5-yl)pyrimidin-2-yl]-N1,N1-dimethylbenzene-1,4-diamine …

N-(3-cyanophenyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)-4-biphenylcarboxamide

Experimental
Matched Name: … N-(3-cyanophenyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)-4-biphenylcarboxamide …
Matched Iupac: … N-(3-cyanophenyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)-[1,1'-biphenyl]-4-carboxamide …

N-(3-TERT-BUTYL-1H-PYRAZOL-5-YL)-N'-{4-CHLORO-3-[(PYRIDIN-3-YLOXY)METHYL]PHENYL}UREA

Experimental
Matched Name: … N-(3-TERT-BUTYL-1H-PYRAZOL-5-YL)-N'-{4-CHLORO-3-[(PYRIDIN-3-YLOXY)METHYL]PHENYL}UREA …
Matched Iupac: … 3-(3-tert-butyl-1H-pyrazol-5-yl)-1-{4-chloro-3-[(pyridin-3-yloxy)methyl]phenyl}urea …

4-({[(4-METHYLPIPERAZIN-1-YL)AMINO]CARBONOTHIOYL}AMINO)BENZENESULFONAMIDE

Experimental
Matched Name: … 4-({[(4-METHYLPIPERAZIN-1-YL)AMINO]CARBONOTHIOYL}AMINO)BENZENESULFONAMIDE …
Matched Iupac: … 1-(4-methylpiperazin-1-yl)-3-(4-sulfamoylphenyl)thiourea …

2-[(4-ETHYNYL-2-FLUOROPHENYL)AMINO]-3,4-DIFLUORO-N-(2-HYDROXYETHOXY)BENZAMIDE

Experimental
Matched Name: … 2-[(4-ETHYNYL-2-FLUOROPHENYL)AMINO]-3,4-DIFLUORO-N-(2-HYDROXYETHOXY)BENZAMIDE …
Matched Iupac: … 2-[(4-ethynyl-2-fluorophenyl)amino]-3,4-difluoro-N-(2-hydroxyethoxy)benzamide …

4-(3-{[5-(trifluoromethyl)pyridin-2-yl]oxy}benzyl)piperidine-1-carboxylic acid

Experimental
Matched Name: … 4-(3-{[5-(trifluoromethyl)pyridin-2-yl]oxy}benzyl)piperidine-1-carboxylic acid …
Matched Iupac: … 4-[(3-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)methyl]piperidine-1-carboxylic acid …

N-HYDROXY-2-[4-(4-PHENOXY-BENZENESULFONYL)-TETRAHYDRO-PYRAN-4-YL]-ACETAMIDE

Experimental
Matched Name: … N-HYDROXY-2-[4-(4-PHENOXY-BENZENESULFONYL)-TETRAHYDRO-PYRAN-4-YL]-ACETAMIDE …
Matched Iupac: … N-hydroxy-2-[4-(4-phenoxybenzenesulfonyl)oxan-4-yl]acetamide …

2-({2-[(3R)-3-AMINOPIPERIDIN-1-YL]-4-OXOQUINAZOLIN-3(4H)-YL}METHYL)BENZONITRILE

Experimental
Matched Name: … 2-({2-[(3R)-3-AMINOPIPERIDIN-1-YL]-4-OXOQUINAZOLIN-3(4H)-YL}METHYL)BENZONITRILE …
Matched Iupac: … 2-({2-[(3R)-3-aminopiperidin-1-yl]-4-oxo-3,4-dihydroquinazolin-3-yl}methyl)benzonitrile …

Cytidine

Experimental
Matched Synonyms: … 4-amino-1-β-D-ribofuranosylpyrimidin-2(1H)-one ... 1-beta-D-Ribofuranosylcytosine ... 4-amino-1β-D-ribofuranosyl-2(1H)-pyrimidinone …
Matched Iupac: … 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Ilomastat

Ilomastat is a broad-spectrum matrix metalloproteinase inhibitor.
Experimental
Matched Synonyms: … (R)-N(SUP 1)-HYDROXY-N-((S)-2-INDOL-3-YL-1-(METHYLCARBAMOYL)ETHYL)-2-ISOBUTYLSUCCINAMIDE ... (S-(R*,S*))-N(SUP 4)-HYDROXY-N(SUP 1)-(1H-INDOL-3-YLMETHYL)-2-(METHYLAMINO)-2-OXOETHYL)-2-(2-METHYLOPROPYL …
Matched Iupac: … (2R)-N'-hydroxy-N-[(1S)-2-(1H-indol-3-yl)-1-(methylcarbamoyl)ethyl]-2-(2-methylpropyl)butanediamide …
Matched Description: … Ilomastat is a broad-spectrum matrix metalloproteinase inhibitor. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Displaying drugs 5926 - 5950 of 6316 in total