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Displaying drugs 576 - 600 of 921 in total

Rosiglitazone

Rosiglitazone is an anti-diabetic drug in the thiazolidinedione class of drugs. It is marketed by the pharmaceutical company GlaxoSmithKline as a stand-alone drug (Avandia) and in combination with metformin (Avandamet) or with glimepiride (Avandaryl). Like other thiazolidinediones, the mechanism of action of rosiglitazone is by activation of the intracellular receptor...
Approved
Investigational
Matched International brands: … Sheng Ao ... Sheng Min …
Matched Description: … Rosiglitazone is a selective ligand of PPARγ, and has no PPARα-binding action. ... It is marketed by the pharmaceutical company GlaxoSmithKline as a stand-alone drug (Avandia) and in combination ... resistance, it appears to have an anti-inflammatory effect: nuclear factor kappa-B (NFκB) levels fall and …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and rosiglitazone ... glimepiride and rosiglitazone …

Dapagliflozin

Dapagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor, and it was the first SLGT2 inhibitor to be approved. indicated for managing diabetes mellitus type 2. When combined with diet and exercise in adults, dapagliflozin helps to improve glycemic control by inhibiting glucose reabsorption in the proximal tubule of the nephron...
Approved
Matched Description: … Dapagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor, and it was the first SLGT2 inhibitor ... by inhibiting glucose reabsorption in the proximal tubule of the nephron and causing glycosuria. ... [A261596] When combined with diet and exercise in adults, dapagliflozin helps to improve glycemic control …
Matched Mixtures name: … Dapagliflozin and Metformin Hydrochloride ... Dapagliflozin and Metformin Hydrochloride ... Qtern 5 mg/10 mg Film-Coated Tablets …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and dapagliflozin ... saxagliptin and dapagliflozin ... sitagliptin and dapagliflozin ... metformin, saxagliptin and dapagliflozin …
Matched Products: … FORXIGA 5MG FILM-COATED TABLET ... FORZIGA 10 MG FILM KAPLI TABLET ,90 FILM KAPLI TABLET IÇEREN 10'LÜK BLISTERLERDE ... FORZIGA 5 MG FILM KAPLI TABLET ,90 FILM KAPLI TABLET IÇEREN 10'LÜK BLISTERLERDE …

Nateglinide

Nateglinide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It belongs to the meglitinide class of short-acting insulin secretagogues, which act by binding to β cells of the pancreas to stimulate insulin release. Nateglinide is an amino acid derivative that induces an early insulin...
Approved
Investigational
Matched Description: … Nateglinide is extensively metabolized in the liver and excreted in urine (83%) and feces (10%). ... insulin and appears to occur only in those naïve to oral antidiabetic agents. ... It should only be taken with meals and meal-time doses should be skipped with any skipped meal. …
Matched Mixtures name: … NAT-ALA 120/200 MG FILM KAPLI TABLET, 90 ADET ... NAT-ALA 180/200 MG FILM KAPLI TABLET, 90 ADET …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …
Matched Products: … NATALIX 120 MG FILM TABLET , FILM TABLET, 84 ADET ... NATALIX 180 MG FILM TABLET , FILM TABLET, 84 ADET ... INGLEX 180 MG FİLM TABLET, 84 ADET …

Riociguat

Riociguat is a soluble guanylate cyclase (sGC) agonist approved in the USA, Europe and several other regions for patients with group I PAH (pulmonary arterial hypertension) in WHO FC II or III; and for the treatment of patients with inoperable CTEPH (chronic thromboembolic pulmonary hypertension), or persistent/recurrent PH (pulmonary hypertension)...
Approved
Matched Description: … regions for patients with group I PAH (pulmonary arterial hypertension) in WHO FC II or III; and for ... Riociguat is a soluble guanylate cyclase (sGC) agonist approved in the USA, Europe and several other ... hypertension), or persistent/recurrent PH (pulmonary hypertension) after pulmonary endarterectomy in WHO …
Matched Products: … Adempas 0.5mg film-coated tablet ... Adempas 1.5mg film-coated tablet ... Adempas 1mg film-coated tablet …

Otilonium

Experimental
Investigational
Matched Mixtures name: … SIMFLAT 40MG/80 MG FİLM KAPLI TABLET, 90 ADET ... DOLOSPAS 40 MG/80 MG FİLM KAPLI TABLET, 90 ADET ... SIMFLAT 40MG/80 MG FİLM KAPLI TABLET, 30 ADET …
Matched Categories: … Alimentary Tract and Metabolism ... Calcium-Regulating Hormones and Agents ... otilonium bromide and psycholeptics …
Matched Products: … EKSPAZ 40 MG FILM TABLET, 60 ADET ... EKSPAZ 40 MG FILM TABLET, 90 ADET ... PENSOTIL 40 MG FILM TABLET,90 ADET …

Pinaverium

Pinaverium is a spasmolytic agent used for functional gastrointestinal disorders. It is a quaternary ammonium compound that acts as an atypical calcium antagonist to restore normal bowel function. It is shown to relieve GI spasm and pain, transit disturbances and other symptoms related to motility disorders and may be considered...
Approved
Matched Description: … It is shown to relieve GI spasm and pain, transit disturbances and other symptoms related to motility ... disorders [A19697] and may be considered as effective first-lline therapy for patients with irritable …
Matched Categories: … Alimentary Tract and Metabolism ... Calcium-Regulating Hormones and Agents …
Matched Products: … DICETEL 100MG FILM-COATED TABLET ... Dicetel 50mg Film-Coated Tablet ... PİNASPAZ 50 MG FİLM KAPLI TABLET, 40 ADET …

Afatinib

Afatinib is a 4-anilinoquinazoline tyrosine kinase inhibitor in the form of a dimaleate salt available as Boehringer Ingelheim's brand name Gilotrif [FDA Label]. For oral use, afatinib tablets are a first-line (initial) treatment for patients with metastatic non-small cell lung cancer (NSCLC) with common epidermal growth factor receptor (EGFR) mutations...
Approved
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … GIOTRIF 20MG FILM-COATED TABLETS ... GIOTRIF 40MG FILM-COATED TABLETS ... GIOTRIF 30MG FILM-COATED TABLETS …

Cabozantinib

Cabozantinib was first approved in 2012 and is a non-specific tyrosine kinase inhibitor. It was initially approved in the US under the brand name Cometriq, which is indicated for the treatment of metastatic medullary thyroid cancer. In 2016, a capsule formulation (Cabometyx) was approved for the treatment of advanced renal...
Approved
Investigational
Matched Description: … Cabozantinib was first approved in 2012 and is a non-specific tyrosine kinase inhibitor. ... a capsule formulation (Cabometyx) was approved for the treatment of advanced renal cell carcinoma, and ... this same formulation gained additional approval in both the US and Canada in 2019 for the treatment …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … CABOMETYX FILM COATED TABLET 20MG ... CABOMETYX FILM COATED TABLET 40MG ... CABOMETYX FILM COATED TABLET 60MG …

Ticagrelor

Ticagrelor, or AZD6140, was first described in the literature in 2003.[A204170,A2903] Ticagrelor is an ADP derivative developed for its P2Y12 receptor antagonism. Unlike clopidogrel, ticagrelor is not a prodrug. It is marketed by Astra Zeneca as Brilinta in the US and Brilique or Possia in the EU, . Ticagrelor was...
Approved
Matched Description: … [A2903] It is marketed by Astra Zeneca as Brilinta in the US[L14201] and Brilique or Possia in the EU …
Matched Categories: … Blood and Blood Forming Organs ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … BRILINTA 90MG FILM-COATED TABLET ... ABRİLOR 60 MG FİLM KAPLI TABLET, 56 ADET ... ALMINDA (FILM-COATED TABLETS 90 MG) …

Secalciferol

Investigational
Matched Synonyms: … Osteo d …

Idebenone

Idebenone is a synthetic analogue of ubiquinone (also known as Coenzyme Q10), a vital cell antioxidant and essential component of the Electron Transport Chain (ETC). It has been proposed that by interacting with the ETC, idebenone increases ATP production required for mitochondrial function, reduces free radicals, inhibits lipid peroxidation, and...
Approved
Investigational
Matched Description: … Idebenone is a synthetic analogue of ubiquinone (also known as Coenzyme Q10), a vital cell antioxidant and ... consequently protects the lipid membrane and mitochondria from oxidative damage [A19768]. ... for its potential use in Alzheimer's Disease and other cognitivie disorders [A19769]. …
Matched Mixtures name: … BERMAXIN 90/10/5 MG FILM TABLET ,FILM TABLET, 28 ADET ... BERMAXIN 90/10/5 MG FILM TABLET ,FILM TABLET, 84 ADET ... EVERON 90/5 MG FILM KAPLI TABLET ,50 TABLET …
Matched Categories: … Enzymes and Coenzymes ... Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Products: … IDEBEX 45 MG FILM KAPLI TABLET ,90 FILM KAPLI TABLET ... IDEBEX 90 MG FILM KAPLI TABLET ,90 FILM KAPLI TABLET ... IDEBEX 45 MG FILM KAPLI TABLET ,FILM KAPLI TABLET, 30 ADET …

Dapoxetine

Dapoxetine is a selective serotonin reuptake inhibitor, for the treatment of premature ejaculation. In a phase II proof-of-concept study conducted by PPD, dapoxetine demonstrated a statistically significant increase in ejaculatory latency when compared to placebo. Alza submitted a NDA to the FDA for dapoxetine for the treatment of premature ejaculation...
Investigational
Matched Mixtures name: … DAPOXIL 30/50 MG FILM KAPLI TABLET,18 FILM KAPLI TABLET ... DAPOKSEL 30 MG/50 MG FILM TABLET ,3 FILM TABLET ... DAPOKSEL 30 MG/50 MG FILM TABLET ,6 FILM TABLET …
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Products: … DAPIGRA 30 MG FILM TABLET ,3 FILM TABLET ... DAPIGRA 30 MG FILM TABLET ,6 FILM TABLET ... DAPIGRA 60 MG FILM TABLET ,3 FILM TABLET …

Erdafitinib

In early April of 2019, the US FDA approved Janssen Pharmaceutical Companies' brand name Balversa (erdafitinib) as the first-ever fibroblast growth factor receptor (FGFR) kinase inhibitor indicated for patients with locally advanced or metastatic urothelial carcinoma, with susceptible FGFR3 or FGFR2 genetic alterations, that has progressed during or following platinum-containing...
Approved
Investigational
Matched Description: … for patients with metastatic bladder cancer, which demonstrates the development of more personalized and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … BALVERSA FILM-COATED TABLETS 3MG ... BALVERSA FILM-COATED TABLETS 5MG ... BALVERSA FILM-COATED TABLETS 4MG …

Brivaracetam

Brivaracetam is a racetam derivative of levetiracetam used in the treatment of partial-onset seizures. Brivaracetam binds SV2A with 20 times higher affinity than levetiracetam . It is available under the brand name Briviact made by UCB. Briviact received FDA approval on February 19, 2016 .
Approved
Investigational
Matched Products: … BRIVIACT 10 MG FILM KAPLI TABLET ,14 FILM KAPLI TABLET ... BRIVIACT 10 MG FILM KAPLI TABLET ,168 FILM KAPLI TABLET ... BRIVIACT 10 MG FILM KAPLI TABLET ,56 FILM KAPLI TABLET …

Macitentan

Macitentan is a dual endothelin receptor antagonist used in the treatment of pulmonary arterial hypertension (PAH). It was first approved by the FDA in 2013. Macitentan differs from its predecessor bosentan in part due to its lower risk of hepatotoxicity. A combination product (Opsynvi) comprising macitentan and tadalafil was approved...
Approved
Matched Description: … A combination product (Opsynvi) comprising macitentan and [tadalafil] was approved in Canada in October …
Matched Categories: … macitentan and tadalafil …
Matched Products: … OPSUMIT FILM-COATED TABLET 10MG ... Opsumit 10mg Film-Coated Tablets ... Opsumit ® 10mg Film-Coated Tablets …

Selexipag

Selexipag was approved by the United States FDA on December 22, 2015 for the treatment of pulmonary arterial hypertension (PAH) to delay disease progression and reduce risk of hospitalization. PAH is a relatively rare disease with usually a poor prognosis requiring more treatment options to prolong long-term outcomes. Marketed by...
Approved
Matched Description: … December 22, 2015 for the treatment of pulmonary arterial hypertension (PAH) to delay disease progression and ... Marketed by Actelion Pharmaceuticals under brand name Uptravi, selexipag and its active metabolite, ACT ... act as agonists of the prostacyclin receptor to increase vasodilation in the pulmonary circulation and …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … UPTRAVI FILM-COATED TABLET 200MCG ... UPTRAVI FILM-COATED TABLETS 400MCG ... UPTRAVI FILM-COATED TABLETS 600MCG …

Maraviroc

Maraviroc (brand-named Selzentry, or Celsentri outside the U.S.) is a chemokine receptor antagonist drug developed by the drug company Pfizer that is designed to act against HIV by interfering with the interaction between HIV and CCR5. It was originally labelled as UK-427857 during development but was assigned the Maraviroc name...
Approved
Investigational
Matched Description: … company Pfizer that is designed to act against HIV by interfering with the interaction between HIV and …
Matched Products: … Celsentri Film-Coated Tablet 300mg ... Celsentri Film-Coated Tablet 150mg ... CELSENTRI 150 MG FILM KAPLI TABLET ,180 ADET …

Etodolac

Etodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic properties. Its therapeutic effects are due to its ability to inhibit prostaglandin synthesis. It is indicated for relief of signs and symptoms of rheumatoid arthritis and osteoarthritis.
Approved
Investigational
Vet approved
Matched Description: … It is indicated for relief of signs and symptoms of rheumatoid arthritis and osteoarthritis. ... Etodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic …
Matched Mixtures name: … ETOTİO 400MG/8MG FİLM KAPLI TABLET, FİLM TABLET, 14 ADET ... ETOTIO 400 MG/8 MG FILM TABLET, 20 ADET ... ETOFAM 400MG/20MG FİLM KAPLI TABLET, 20 ADET …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … BARCA 500 MG FILM TABLET, 14 ADET ... CIRRINAL 200 MG FILM TABLET, 20 ADET ... EDOLAR 600 MG FILM TABLET, 10 ADET …

Erlotinib

Erlotinib is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase that is used in the treatment of non-small cell lung cancer, pancreatic cancer and several other types of cancer. It is typically marketed under the trade name Tarceva. Erlotinib binds to the epidermal growth factor receptor (EGFR)...
Approved
Investigational
Matched Description: … EGFR) tyrosine kinase that is used in the treatment of non-small cell lung cancer, pancreatic cancer and ... , which is a mutant form of tyrosine kinase JAK2 found in most patients with polycythemia vera (PV) and ... This finding introduces the potential use of erlotinib in the treatment of JAK2V617F-positive PV and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … TARCEVA FILM-COATED TABLET 25 MG ... TARCEVA FILM-COATED TABLET 100 MG ... TARCEVA FILM-COATED TABLET 150 MG …

Edoxaban

Edoxaban is a member of the Novel Oral Anti-Coagulants (NOACs) class of drugs, and is a rapidly acting, oral, selective factor Xa inhibitor. By inhibiting factor Xa, a key protein in the coagulation cascade, edoxaban prevents the stepwise amplification of protein factors needed to form blood clots. It is indicated...
Approved
Matched Description: … INR testing, and numerous drug-drug and drug-food interactions. ... atrial fibrillation (NVAF) and for the treatment of deep vein thrombosis (DVT) and pulmonary embolism ... Edoxaban is a member of the Novel Oral Anti-Coagulants (NOACs) class of drugs, and is a rapidly acting …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … LIXIANA FILM-COATED TABLET 30 MG ... LIXIANA FILM-COATED TABLET 60 MG ... LIXIANA FILM-COATED TABLET 15 MG …

Favipiravir

Discovered by Toyama Chemical Co., Ltd. in Japan, favipiravir is a modified pyrazine analog that was initially approved for therapeutic use in resistant cases of influenza.[A191688,A191721] The antiviral targets RNA-dependent RNA polymerase (RdRp) enzymes, which are necessary for the transcription and replication of viral genomes.[A191688,A191772,A191775] Not only does favipiravir inhibit...
Approved
Investigational
Matched Description: … [A191688,A191772,A191775] Not only does favipiravir inhibit replication of influenza A and B, but ... antiviral targets RNA-dependent RNA polymerase (RdRp) enzymes, which are necessary for the transcription and ... the drug has shown promise in the treatment of avian influenza, and may be an alternative option for …
Matched Products: … AVIGAN Film-Coated Tablets 200mg (Favipiravir) ... KOVİPİR 200 MG FİLM KAPLI TABLET, 40 ADET ... FAVİRA 200 MG FİLM KAPLI TABLET, 40 ADET …

Escitalopram

Escitalopram is a selective serotonin re-uptake inhibitor (SSRI) and the S-enantiomer of racemic citalopram. It is used to restore serotonergic function in the treatment of depression and anxiety.[L8513,L8516,L8522] Escitalopram is approximately 150 times more potent than citalopram’s R-enantiomer and is responsible for the vast majority of citalopram’s clinical activity, with...
Approved
Matched Description: … Escitalopram is a selective serotonin re-uptake inhibitor (SSRI) and the S-enantiomer of racemic [citalopram ... [A185420] It is used to restore serotonergic function in the treatment of depression and anxiety. ... L8513,L8516,L8522] Escitalopram is approximately 150 times more potent than citalopram’s R-enantiomer and …
Matched Products: … ANZYL 10 MG FILM TABLET ,56 FILM TABLET ... ANZYL 20 MG FILM TABLET ,56 FILM TABLET ... ANZYL 5 MG FILM TABLET ,FILM TABLET, 28 ADET …

Eltrombopag

Eltrombopag is used to treat low blood platelet counts in adults with chronic immune (idiopathic) thrombocytopenia (ITP), when certain other medicines, or surgery to remove the spleen, have not worked well enough. ITP is a condition that may cause unusual bruising or bleeding due to an abnormally low number of...
Approved
Matched Description: … thrombocytopenia (low blood platelet counts) in patients with chronic hepatitis C to allow them to initiate and …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … REVOLADE FILM-COATED TABLET 25MG ... REVOLADE FILM-COATED TABLET 50MG ... REVOLADE 12.5 MG FİLM TABLET, 14 ADET …

Gemifloxacin

Gemifloxacin is a quinolone antibacterial agent with a broad-spectrum activity that is used in the treatment of acute bacterial exacerbation of chronic bronchitis and mild-to-moderate pneumonia. It is available in oral formulations. Gemifloxacin acts by inhibiting DNA synthesis through the inhibition of both DNA gyrase and topoisomerase IV, which are...
Approved
Investigational
Matched Description: … broad-spectrum activity that is used in the treatment of acute bacterial exacerbation of chronic bronchitis and ... Gemifloxacin acts by inhibiting DNA synthesis through the inhibition of both DNA gyrase and topoisomerase …
Matched Products: … Factive film-coated tablet 320 mg ... ONFACT 320 MG FİLM TABLET, 5 ADET ... ONFACT 320 MG FİLM TABLET, 7 ADET …

Trametinib

Trametinib is an orally bioavailable mitogen-activated extracellular signal-regulated kinase 1 (MEK1) and MEK2 inhibitor.[A258298,A258293] It was first approved by the FDA in May 2013 for the treatment of melanoma. It was later approved by Health Canada on July 18, 2013 and by the European Commission on June 30, 2014. Trametinib...
Approved
Matched Description: … Trametinib is an orally bioavailable mitogen-activated extracellular signal-regulated kinase 1 (MEK1) and ... [A258298] It was later approved by Health Canada on July 18, 2013 [L45588] and by the European Commission ... currently approved to treat a variety of cancers with BRAF mutations, such as non-small cell lung cancer and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … MEKINIST FILM-COATED TABLETS 2MG ... Meqsel 2mg Film-Coated Tablet ... MEKINIST FILM-COATED TABLETS 0.5MG …
Displaying drugs 576 - 600 of 921 in total