Displaying drugs 576 - 600 of 661 in total
Alnuctamab
Investigational
Matched Synonyms: … immunoglobulin G1 (IgG1)-based, B-cell maturation antigen (BCMA) x CD3 T-cell bispecific monoclonal antibody …
OMS906
OMS906 is a humanized Igg4 monoclonal antibody against mannan-binding lectin-associated serine protease-3 (MASP-3) currently being developed by Omeros.
Investigational
Matched Synonyms: … Humanized immunoglobulin G4 monoclonal antibody directed against mannan-binding lectin-associated serine …
Matched Description: … OMS906 is a humanized Igg4 monoclonal antibody against mannan-binding lectin-associated serine protease …
Matched Description: … OMS906 is a humanized Igg4 monoclonal antibody against mannan-binding lectin-associated serine protease …
Indatuximab ravtansine
Indatuximab ravtansine is under investigation in clinical trial NCT01001442 (Safety and Dose Determining Multi-dose Study of BT062 in Patients With Relapsed or Refractory Multiple Myeloma).
Investigational
Matched Synonyms: … Deacetyl-N2'-[4-Methyl-4-(Oxobuthyldithio)-1-Oxopentyl]-Maytansine-Chimerized Anti-Cd138 Igg4 Monoclonal Antibody …
Matched Description: … Indatuximab ravtansine is under investigation in clinical trial NCT01001442 (Safety and Dose Determining …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antibody-drug Conjugates …
Matched Description: … Indatuximab ravtansine is under investigation in clinical trial NCT01001442 (Safety and Dose Determining …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antibody-drug Conjugates …
Zinlirvimab
Zinlirvimab is under investigation in clinical trial NCT03707977 (Dual Bnab Treatment in Children).
Investigational
Matched Synonyms: … Anti-hiv-1 human monoclonal antibody targeting v3 glycan supersite on the hiv-1 envelope protein (10- …
Flurbiprofen
Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity. Oral formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and anklylosing spondylitis. Flurbiprofen may also be used topically prior to ocular surgery to prevent or reduce intraoperative miosis....
Approved
Investigational
Matched Description: … Flurbiprofen is structurally and pharmacologically related to fenoprofen, ibuprofen, and ketoprofen. ... Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and ... formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Strepsils MaxPro Honey and Lemon lozenges 8.75mg …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Strepsils MaxPro Honey and Lemon lozenges 8.75mg …
Acazicolcept
Investigational
Matched Synonyms: … cell costimulator ligand variant immunoglobulin domain designed to inhibit simultaneously the CD28 and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Sirexatamab
Investigational
Matched Synonyms: … Anti-dkk-1 monoclonal antibody ly2812176 ... Dkk1-neutralizing monoclonal antibody dkn-01 …
Roledumab
Roledumab is under investigation in clinical trial NCT02287896 (Pharmacokinetics and Safety of Roledumab in Rhd-negative Pregnant Women Carrying an Rhd-positive Foetus).
Investigational
Matched Synonyms: … -kappa, anti-(homo sapiens rhd(rhesus blood group d antigen, rhd, cd240d)), homo sapiens monoclonal antibody …
Matched Description: … Roledumab is under investigation in clinical trial NCT02287896 (Pharmacokinetics and Safety of Roledumab …
Matched Description: … Roledumab is under investigation in clinical trial NCT02287896 (Pharmacokinetics and Safety of Roledumab …
Tegoprubart
Investigational
Matched Synonyms: … Humanized Anti-Cd40Lg Igg1, Kappa Monoclonal Antibody With Heavy Chain C220S/C226S/C229S/P238S Substitutions …
Apamistamab iodine I-131
Investigational
Matched Synonyms: … 131I-BC8 monoclonal antibody (Anti-CD45 murine monoclonal antibody radiolabeled with 131I …
Aripiprazole
Aripiprazole is an atypical antipsychotic orally indicated for the treatment of schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's. It is also indicated as an injection for agitation associated with schizophrenia or bipolar mania. Aripiprazole exerts its effects through agonism of dopaminergic and 5-HT1A receptors and...
Approved
Investigational
Matched Description: … [L45859] Aripiprazole exerts its effects through agonism of dopaminergic and 5-HT1A receptors and antagonism ... of alpha-adrenergic and 5-HT2A receptors. ... treatment of schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and …
Matched Categories: … Aripiprazole and prodrugs ... Potential QTc-Prolonging Agents …
Matched Products: … Abilify Maintena 400 mg powder and solvent for prolonged-release suspension for injection ... ABILIFY MAINTENA POWDER AND SOLVENT FOR PROLONGED RELEASE SUSPENSION FOR INJECTION 400 MG …
Matched Categories: … Aripiprazole and prodrugs ... Potential QTc-Prolonging Agents …
Matched Products: … Abilify Maintena 400 mg powder and solvent for prolonged-release suspension for injection ... ABILIFY MAINTENA POWDER AND SOLVENT FOR PROLONGED RELEASE SUSPENSION FOR INJECTION 400 MG …
Imalumab
Imalumab is under investigation in clinical trial NCT02540356 (Phase 1/2a Two-arm Dose-escalation Study of BAX69 in Subjects With Malignant Ascites of Ovarian Cancer).
Investigational
Matched Synonyms: … migration inhibitory factor, glycosylation-inhibiting factor, glif, gif)), homo sapiens monoclonal antibody …
STM-217
Investigational
Matched Synonyms: … Soluble receptor fused to part of an antibody that is designed to block the growth factor activin a …
FB-825
FB-825 is an investigational humanized monoclonal antibody that targets the CεmX domain of the membrane-bound IgE (mIgE), causing a depletion of mIgE positive B-cells. It is currently being investigated for immune disorders, such as atopic dermatitis and hyperimmunoglobulin E syndrome (HIES).[A258448,L45743]
Investigational
Matched Synonyms: … Recombinant humanized immunoglobulin gamma 1 monoclonal antibody (mAb) directed against the CemX segment …
Matched Description: … It is currently being investigated for immune disorders, such as atopic dermatitis and hyperimmunoglobulin ... FB-825 is an investigational humanized monoclonal antibody that targets the CεmX domain of the membrane-bound …
Matched Description: … It is currently being investigated for immune disorders, such as atopic dermatitis and hyperimmunoglobulin ... FB-825 is an investigational humanized monoclonal antibody that targets the CεmX domain of the membrane-bound …
Efineptakin alfa
Efineptakin alfa (also known as NT-I7) is a long-acting human interleukin-7 (IL-7) fusion protein that promotes T-cell development, contributing to the immune response. Compared to endogenous IL-7, NT-I7 is more stable and potent, has a longer half-life, and has better bioavailability. This drug is currently being investigated in the areas...
Investigational
Matched Synonyms: … Recombinant human interleukin-7 fused to a hybrid crystallizable fragment region of a human antibody ... Recombinant human interleukin-7 fused to a hybrid crystallizable fragment region of a human antibody …
Matched Description: … Compared to endogenous IL-7, NT-I7 is more stable and potent, has a longer half-life, and has better ... This drug is currently being investigated in the areas of oncology, immunology, and infectious disease …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Description: … Compared to endogenous IL-7, NT-I7 is more stable and potent, has a longer half-life, and has better ... This drug is currently being investigated in the areas of oncology, immunology, and infectious disease …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Bersanlimab
Bersanlimab is an investigational monoclonal antibody directed against intercellular adhesion molecule 1 (ICAM-1).
Investigational
Matched Synonyms: … Anti-icam-1 monoclonal antibody bi-505 ... lambda, anti-(homo sapiens icam1(intercellular adhesion molecule 1, icam-1, cd54)), human monoclonal antibody …
Matched Description: … Bersanlimab is an investigational monoclonal antibody directed against intercellular adhesion molecule …
Matched Description: … Bersanlimab is an investigational monoclonal antibody directed against intercellular adhesion molecule …
Ascorbic acid
A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic...
Approved
Nutraceutical
Matched Description: … Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and ... It is found naturally in citrus fruits and many vegetables. ... Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic …
Matched Mixtures name: … Hvp Chelated Cal/mag With Zinc and Vitamins C and D ... CALCIUM AND MAGNESIUM PLUS C,POTASSIUM AND ZINC TABLET ... Cold and Sinus …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition ... Vitamin C and analogues ... ascorbic acid (vit C) and calcium ... Genito Urinary System and Sex Hormones …
Matched Products: … Sodium Ascorbate and Ascorbic Acid Pwr ... Vit.c With N-M.bioflav.rose Hips and Rutin ... Timed Release and Esterified Vitamin C-1000 …
Matched Mixtures name: … Hvp Chelated Cal/mag With Zinc and Vitamins C and D ... CALCIUM AND MAGNESIUM PLUS C,POTASSIUM AND ZINC TABLET ... Cold and Sinus …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition ... Vitamin C and analogues ... ascorbic acid (vit C) and calcium ... Genito Urinary System and Sex Hormones …
Matched Products: … Sodium Ascorbate and Ascorbic Acid Pwr ... Vit.c With N-M.bioflav.rose Hips and Rutin ... Timed Release and Esterified Vitamin C-1000 …
Brentuximab vedotin
Brentuximab vedotin, also known as Adcetris®, is an antibody-drug conjugate that combines an anti-CD30 antibody with the drug monomethyl auristatin E (MMAE). It is an anti-neoplastic agent used in the treatment of Hodgkin's lymphoma and systemic anaplastic large-cell lymphoma. Brentuximab vedotin was initially approved in 2011. In January 2012, the...
Approved
Investigational
Matched Synonyms: … Monoclonal antibody SGN-30 …
Matched Description: … antibody with the drug monomethyl auristatin E (MMAE). ... Brentuximab vedotin, also known as Adcetris®, is an antibody-drug conjugate that combines an anti-CD30 ... Lymphoma may begin anywhere in the body and can spread to nearby lymph nodes. …
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Antibody-drug Conjugates ... CD30-directed Antibody Interactions …
Matched Description: … antibody with the drug monomethyl auristatin E (MMAE). ... Brentuximab vedotin, also known as Adcetris®, is an antibody-drug conjugate that combines an anti-CD30 ... Lymphoma may begin anywhere in the body and can spread to nearby lymph nodes. …
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Antibody-drug Conjugates ... CD30-directed Antibody Interactions …
Narsoplimab
Thrombotic microangiopathies (TMA), including thrombotic thrombocytopenic purpura and atypical hemolytic uremic syndrome, are associated with injury and dysregulation of microvascular endothelium and platelets. Evidence increasingly points to a role for the complement system in TMA.[A241030, A241040] Mannan-associated lectin-binding serine protease-2 (MASP-2) is a major effector in the complement lectin pathway.[A241030,...
Investigational
Matched Synonyms: … MASP-2 antibody ... ANTI-MASP-2 MONOCLONAL ANTIBODY OMS721 ... SERINE PROTEASE 2 (MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASE 2, EC=3.4.21.104) HUMAN MONOCLONAL ANTIBODY …
Matched Description: … [A241030, A241040] Narsoplimab (OMS721), a human IgG4λ anti-MASP-2 antibody, is under consideration as ... uremic syndrome, are associated with injury and dysregulation of microvascular endothelium and platelets ... Thrombotic microangiopathies (TMA), including thrombotic thrombocytopenic purpura and atypical hemolytic …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … [A241030, A241040] Narsoplimab (OMS721), a human IgG4λ anti-MASP-2 antibody, is under consideration as ... uremic syndrome, are associated with injury and dysregulation of microvascular endothelium and platelets ... Thrombotic microangiopathies (TMA), including thrombotic thrombocytopenic purpura and atypical hemolytic …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Veligrotug
Veligrotug is under investigation in clinical trial NCT00791544 (Dose Finding Study of AVE1642 in Patients With Advanced or Metastatic Liver Carcinoma).
Investigational
Matched Synonyms: … Anti-cd122 monoclonal antibody ave1642 ... Anti-igf-1r monoclonal antibody ave1642 ... sapiens IGF1R (insulin-like growth factor 1 receptor, IGF1-R, IGF-1R, CD221)], chimeric monoclonal antibody …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
NBL-015
Investigational
Matched Synonyms: … Fully human monoclonal IgG1 antibody against the type 2 isoform of human Claudin 18 protein (Claudin …
Pyridostigmine
Myasthenia gravis is an autoimmune disease involving dysfunction at the neuromuscular junction, most commonly due to autoantibodies directed against the acetylcholine receptor (AChR), which results in muscle tone loss, muscle weakness, and fatigue. Acetylcholinesterase inhibitors have been the symptomatic treatment of choice in myasthenia gravis since the 1930s with the...
Approved
Investigational
Matched International brands: … Antilon …
Matched Description: … under various brand and generic names. ... directed against the acetylcholine receptor (AChR), which results in muscle tone loss, muscle weakness, and ... By inhibiting the breakdown of acetylcholine in the neuromuscular junction, they increase signalling and …
Matched Description: … under various brand and generic names. ... directed against the acetylcholine receptor (AChR), which results in muscle tone loss, muscle weakness, and ... By inhibiting the breakdown of acetylcholine in the neuromuscular junction, they increase signalling and …
Somatrogon
Somatrogon is a long-acting recombinant human growth hormone. Growth hormone is a peptide hormone secreted by the pituitary gland that plays a crucial role in promoting longitudinal growth during childhood and adolescence and regulating metabolic function in adulthood. Recombinant growth hormone therapy for growth hormone deficiency and other conditions has...
Approved
Matched Synonyms: … .)-(118-145)-PEPTIDE (1-28) WITH HUMAN SOMATOTROPIN (GROWTH HORMONE, GH) (29-219) AND TWO TANDEM COPIES …
Matched Description: … of somatrogon and allows its once-weekly dosing. ... adolescence and regulating metabolic function in adulthood. ... by the pituitary gland that plays a crucial role in promoting longitudinal growth during childhood and …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins ... Somatropin and Somatropin Agonists ... Anterior Pituitary Lobe Hormones and Analogues …
Matched Description: … of somatrogon and allows its once-weekly dosing. ... adolescence and regulating metabolic function in adulthood. ... by the pituitary gland that plays a crucial role in promoting longitudinal growth during childhood and …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins ... Somatropin and Somatropin Agonists ... Anterior Pituitary Lobe Hormones and Analogues …
Docetaxel
Docetaxel is a clinically well established anti-mitotic chemotherapy medication used for the treatment of different types of cancer, including breast, ovarian, and non-small cell lung cancer. Docetaxel is a complex diterpenoid molecule and a semisynthetic analogue of paclitaxel.[A259676,L46466] Docetaxel reversibly binds to microtubulin with high affinity in a 1:1 stoichiometric...
Approved
Investigational
Matched Description: … Docetaxel is a complex diterpenoid molecule and a semisynthetic analogue of [paclitaxel]. ... chemotherapy medication used for the treatment of different types of cancer, including breast, ovarian, and ... microtubulin with high affinity in a 1:1 stoichiometric ratio, allowing it to prevent cell division and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Oncotaxel Concentrate and solvent for solution for infusion 40 mg/ ml …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Oncotaxel Concentrate and solvent for solution for infusion 40 mg/ ml …
Loncastuximab tesirine
Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients who have undergone prior systemic therapies with limited success. Prognosis is poor and more effective therapies are needed to treat relapsed/refractory cases and improve survival. On April 23 2021, the Food and Drug Administration granted accelerated...
Approved
Investigational
Matched Synonyms: … Humanized monoclonal immunoglobulin G1 antibody directed against human CD19 conjugated to SG3199 through …
Matched Description: … [A234444] On April 23 2021, the Food and Drug Administration granted accelerated approval for the antibody-drug ... and improve survival. ... Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients …
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Antibody-drug Conjugates ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Description: … [A234444] On April 23 2021, the Food and Drug Administration granted accelerated approval for the antibody-drug ... and improve survival. ... Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients …
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Antibody-drug Conjugates ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Displaying drugs 576 - 600 of 661 in total