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Displaying drugs 576 - 600 of 2941 in total

Mecasermin

Mecasermin contains recombinant-DNA-engineered human insulin-like growth factor-1 (rhIGF-1)[FDA Label]. IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges and a molecular weight of 7649 daltons. The amino acid sequence of the product is identical to that of endogenous human IGF-1. The rhIGF-1 protein is...
Approved
Investigational
Matched Synonyms: … INSULIN-LIKE GROWTH FACTOR I (HUMAN) ... RECOMBINANT HUMAN INSULIN-LIKE GROWTH FACTOR-I ... Human somatomedin C …
Matched Description: … Mecasermin contains recombinant-DNA-engineered human insulin-like growth factor-1 (rhIGF-1)[FDA Label ... The amino acid sequence of the product is identical to that of endogenous human IGF-1. ... protein is synthesized in bacteria (E. coli) that have been modified by the addition of the gene for human …
Matched Categories: … Human Insulin-like Growth Factor Analogs ... Recombinant Human Insulin-like Growth Factor-1 …

Urofollitropin

Urofollitropin is a urinary-derived follicle-stimulating hormone (FSH) that is extracted and purified from human urine samples. It consists of two non-covalently linked, non-identical glycoproteins designated as the alpha- and beta- subunits. The alpha- and beta- subunits have 92 and 111 amino acids. The alpha subunit is glycosylated at Asn 51...
Approved
Vet approved
Matched Synonyms: … Follitropin human …
Matched Description: … Urofollitropin is a urinary-derived follicle-stimulating hormone (FSH) that is extracted and purified from human ... Urofollitropin is typically used injected subcutaneously in combination with human chorionic gonadotropin …

Abciximab

Abciximab is a Fab fragment of the chimeric human-murine monoclonal antibody 7E3. Abciximab binds to the glycoprotein (GP) IIb/IIIa receptor of human platelets and inhibits platelet aggregation by preventing the binding of fibrinogen, von Willebrand factor, and other adhesive molecules. It also binds to vitronectin (αvβ3) receptor found on platelets...
Approved
Matched Description: … by preventing the binding of fibrinogen, von Willebrand factor, and other adhesive molecules. ... Abciximab is a Fab fragment of the chimeric human-murine monoclonal antibody 7E3. ... Abciximab binds to the glycoprotein (GP) IIb/IIIa receptor of human platelets and inhibits platelet aggregation …

Rabies virus inactivated antigen, B

Inactivated rabies virus antigen B is a component of rabies vaccines used for pre- and post-exposure prophylaxis against rabies.
Approved
Matched Synonyms: … Rabies virus vaccine wistar strain PM-1503-3M (human) …
Matched Products: … RABIES VACCINE FOR HUMAN USE (VERO CELL), FREEZE-DRIED FINAL BULK …

Adenovirus type 7 vaccine live

Approved
Matched Synonyms: … Human adenovirus B serotype 7 strain 55142 antigen …
Matched Categories: … Live Human Adenovirus Type 7 Vaccine …

Fidanacogene elaparvovec

Fidanacogene elaparvovec is a liver-specific adeno-associated virus (AAV) vector containing a codon-optimized human coagulation FIX gene that was investigated as a potential treatment for hemophilia B. Hemophilia B is a rare X-linked genetic disorder characterized by abnormal coagulation due to dysfunctional coagulation factor IX with a male incidence estimated to...
Approved
Investigational
Matched Description: … dysfunctional coagulation factor IX with a male incidence estimated to be 1 in 30,000 male births worldwide ... Fidanacogene elaparvovec is a liver-specific adeno-associated virus (AAV) vector containing a codon-optimized human ... coagulation FIX gene that was investigated as a potential treatment for hemophilia B. …

Teriparatide

Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. It is made up of the first amino(N)-terminal 34 amino acids of the human PTH. First approved in the United States in November 2002 and in Europe in April 2003, teriparatide makes the first approved drug in...
Approved
Investigational
Matched Synonyms: … Teriparatide recombinant human …
Matched Description: … [A251395] It is made up of the first amino(N)-terminal 34 amino acids of the human PTH. …

Pemigatinib

Pemigatinib is a small molecule kinase inhibitor with antitumour activity. It works by inhibiting fibroblast growth factor receptors (FGFRs), which are receptor tyrosine kinases that activate signalling pathways in tumour cells. FGFRs gained attention as potential therapeutic targets in selected cancers, as FGFR gene alterations were observed in a wide...
Approved
Investigational
Matched Description: … It works by inhibiting fibroblast growth factor receptors (FGFRs), which are receptor tyrosine kinases ... advanced or metastatic cholangiocarcinoma in previously treated adult patients with a fibroblast growth factor ... intrahepatic cholangiocarcinoma exhibited gene rearrangements resulting in oncogenic fibroblast growth factor …
Matched Categories: … Fibroblast Growth Factor 2, antagonists & inhibitors ... Receptors, Fibroblast Growth Factor, antagonists & inhibitors ... Fibroblast growth factor receptor (FGFR) tyrosine kinase inhibitors ... Receptor, Fibroblast Growth Factor, Type 1, antagonists & inhibitors ... Receptor, Fibroblast Growth Factor, Type 2, antagonists & inhibitors …

Menotropins

Menotropins contains follicle stimulating hormone (FSH) and luteinizing hormone (LH) purified from the urine of postmenopausal women. It is used as a fertility medication that is injected either subcutaneously or intramuscularly. It is composed of LH with 2 subunits, alpha = 92 residues, beta = 121 residues and FSH with...
Approved
Matched Synonyms: … Human menopausal gonadotrophin …
Matched Categories: … Complex Mixtures ... human menopausal gonadotrophin …

Lecanemab

Lecanemab is a recombinant humanized immunoglobulin gamma 1 (IgG1) monoclonal antibody directed against aggregated soluble and insoluble forms of amyloid beta (Aβ), which are implicated in the pathophysiology of Alzheimer’s disease. Lecanemab works to reduce Aβ plaques and prevent Aβ deposition in the brain [A253947,A253952] with high selectivity to Aβ...
Approved
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human beta-amyloid protofibril) (human-mus musculus monoclonal BAN2401 heavy ... chain), disulfide with human-mus musculus monoclonal BAN2401 light chain, dimer …

Allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen

Stratagraft (allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat) is an allogeneic cellularized scaffold product used for the treatment of adults with thermal burns containing intact dermal elements for which surgical intervention is clinically indicated (also known as deep partial-thickness burns). It was developed as an alternative to autografting...
Approved
Matched Synonyms: … Viable and metabolically active allogeneic human NIKS keratinocytes and human dermal fibroblasts cellularized …
Matched Description: … applied to the burn site and, as they contain metabolically active and viable cells, provide a variety of human …

Angiotensin II

Angiotensin II is under investigation for the treatment of Sepsis, Septic Shock, Diabetes Mellitus, and Acute Renal Failure. Angiotensin II has been investigated for the treatment, basic science, and diagnostic of Hypertension, Renin Angiotensin System, and Idiopathic Membranous Nephropathy. As of December 21, 2017 the FDA approved La Jolla Pharmaceutical's...
Approved
Investigational
Matched Synonyms: … Human angiotensin II ... Angiotensin II (human) …
Matched Description: … The novelty of the medication lies in the fact that it is the first and only use of synthetic human angiotensin …

Anthrax immune globulin human

Anthrax immune globulin is a human antibody given with antibiotics for the treatment of anthrax. It is derived from the plasma of humans immunized with BioThrax (adsorbed anthrax vaccine), which is then further purified. Available as the product Anthrasil (FDA), the result is a solution for slow IV infusion containing...
Approved
Matched Synonyms: … Anthrax immune globulin human ... Anthrax immune globulin (human) ... Anthrax immunoglobulin (human) …
Matched Name: … Anthrax immune globulin human …
Matched Description: … Anthrax immune globulin is a human antibody given with antibiotics for the treatment of anthrax. …
Matched Categories: … Human Immunoglobulin …

Human albumin microspheres

Approved
Experimental
Matched Synonyms: … Albumin human, microspheres ... Albumin microsphere human serum ... Albumin, microsphere human serum …
Matched Name: … Human albumin microspheres …

Dornase alfa

Dornase alfa is a biosynthetic form of human deoxyribunuclease I (DNase I) enzyme. It is produced in genetically modified Chinese hamster ovary (CHO) cells using recombinant DNA technology. The 260-amino acid sequence of dornase alfa is identical to the endogenous human enzyme. Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and...
Approved
Matched Synonyms: … Deoxyribonuclease (human clone 18-1 protein moiety) …
Matched Description: … Dornase alfa is a biosynthetic form of human deoxyribunuclease I (DNase I) enzyme. ... The 260-amino acid sequence of dornase alfa is identical to the endogenous human enzyme. …
Matched Categories: … Recombinant Human Deoxyribonuclease 1 …

Tetanus immune globulin, human

Tetanus Immune Globulin is manufactured from human plasma [FDA Label]. It contains antibodies against tetanus toxoid and is primarily used as prophylaxis against tetanus in wounded patients.
Approved
Matched Synonyms: … Tetanus immune globulin human ... Tetanus immune globulin,human ... Tetanus immunoglobulin (human) …
Matched Name: … Tetanus immune globulin, human …
Matched Description: … Tetanus Immune Globulin is manufactured from human plasma [FDA Label]. …
Matched Categories: … Human Tetanus Immune Globulins …

Apixaban

Apixaban is an oral, direct, and highly selective factor Xa (FXa) inhibitor of both free and bound FXa, as well as prothrombinase, independent of antithrombin III for the prevention and treatment of thromboembolic diseases[Label,A6897]. It is marketed under the name Eliquis[Label,L6043]. Apixaban was approved by the FDA on December 28,...
Approved
Matched Description: … Apixaban is an oral, direct, and highly selective factor Xa (FXa) inhibitor of both free and bound FXa …
Matched Categories: … Factor Xa Inhibitors ... Direct factor Xa inhibitors …

Insulin lispro

Insulin lispro is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the pancreas...
Approved
Matched Synonyms: … Insulin,lispro,human/rDNA …
Matched Description: … is prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human ... then to a monomer that is absorbed more rapidly after subcutaneous injection compared to endogenous human ... Formerly called LYSPRO from the chemical nomenclature [LYS(B28), PRO(B29)], insulin lispro differs from human …

Laronidase

Human recombinant alpha-L-iduronidase, 628 residues (mature form), produced by recombinant DNAtechnology in a Chinese hamster ovary cell line. Laronidase is a glycoprotein with a molecular weight of approximately 83 kD. The predicted amino acid sequence of the recombinant form, as well as the nucleotide sequence that encodes it, are identical...
Approved
Matched Synonyms: … Human Recombinant alpha-L-iduronidase …
Matched Description: … Human recombinant alpha-L-iduronidase, 628 residues (mature form), produced by recombinant DNAtechnology ... recombinant form, as well as the nucleotide sequence that encodes it, are identical to a polymorphic form of human …

Nadroparin

Nadroparin is a low molecular weight heparin (LMWH) which, when bound to antithrombin III (ATIII), accelerates the inactivation of factor II and factor Xa. Nadroparin halts the coagulation pathway by inhibiting the activation of thrombin (factor IIa) by factor Xa. The amplification of the fibrin clotting cascade is stopped once...
Approved
Investigational
Matched Description: … Nadroparin halts the coagulation pathway by inhibiting the activation of thrombin (factor IIa) by factor ... II and factor Xa. ... weight heparin (LMWH) which, when bound to antithrombin III (ATIII), accelerates the inactivation of factor …

Eptifibatide

Synthetic cyclic hexapeptide that binds to platelet receptor glycoprotein and inhibits platelet aggregation. Derived from venom of the Southeastern pygmy rattlesnake (Sistrurus miliarus barbouri), eptifibatide is a cyclic heptapeptide that belongs to the class of arginin-glycin-aspartat-mimetics.
Approved
Investigational

Ramucirumab

Ramucirumab is a human monoclonal antibody (IgG1) against vascular endothelial growth factor receptor 2 (VEGFR2), a type II trans-membrane tyrosine kinase receptor expressed on endothelial cells. By binding to VEGFR2, ramucirumab prevents binding of its ligands (VEGF-A, VEGF-C, and VEGF-D), thereby preventing VEGF-stimulated receptor phosphorylation and downstream ligand-induced proliferation, permeability,...
Approved
Investigational
Matched Description: … Ramucirumab is a human monoclonal antibody (IgG1) against vascular endothelial growth factor receptor ... receptor phosphorylation and downstream ligand-induced proliferation, permeability, and migration of human …
Matched Categories: … Vascular Endothelial Growth Factor Receptor 2 Antagonist ... VEGF/VEGFR (Vascular Endothelial Growth Factor) inhibitors …

Interferon alfa-2a

Interferon a (human leukocyte protein moiety reduced). A type I interferon consisting of 165 amino acid residues with lysine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent. An oral form is...
Approved
Investigational
Matched Synonyms: … Recombinant human interferon alfa-2a ... Recombinant human interferon-alfa-2a …
Matched Description: … Interferon a (human leukocyte protein moiety reduced). …

Follitropin

Follitropin is a human follicle stimulating hormone (FSH) preparation of recombinant DNA origin, which consists of two non-covalently linked, non-identical glycoproteins designated as the alpha- and beta- subunits. The alpha- and beta- subunits have 92 and 111 amino acids. The alpha subunit is glycosylated at Asn 51 and Asn 78...
Approved
Matched Synonyms: … Recombinant human follicle stimulating hormone beta ... Recombinant human follicle-stimulating hormone (r-HFSH) …
Matched Description: … Follitropin is a human follicle stimulating hormone (FSH) preparation of recombinant DNA origin, which ... The nomenclature “beta” differentiates it from another recombinant human FSH product that was marketed ... Given by subcutaneous injection, it is used in combination with human chorionic gonadotropin (hCG) to …

Dalteparin

Dalteparin, a low molecular weight heparin (LMWH) prepared by nitrous acid degradation of unfractionated heparin of porcine intestinal mucosa origin, is an anticoagulant. It is composed of strongly acidic sulphated polysaccharide chains with an average molecular weight of 5000 and about 90% of the material within the range of 2000-9000....
Approved
Matched Description: … Low molecular weight heparins are less effective at inactivating factor IIa due to their shorter length …
Matched Products: … FRAGMIN® 10000 UIANTI FACTOR - XA / 0.4 ML SOLUCION INYECTABLE …
Displaying drugs 576 - 600 of 2941 in total