Did you mean 17673 2,3 5?
Displaying drugs 6101 - 6125 of 9359 in total
Zanidatamab zovodotin
According to Zymeworks, "ZW49 (zanidatamab zovodotin) is a bispecific anti-HER2 ADC that is based on the same antibody framework as ZW25 but armed with a cytotoxic payload." It is being investigated for several indications characterized by HER2 expression including breast and gastric cancers that have progressed or are refractory to...
Investigational
Methylisothiazolinone
Experimental
Matched Synonyms: … 2-Methyl-3-isothiazolone ... 2-Methyl-3(2H)-isothiazolone ... 2-Methyl-4-isothiazolin-3-one …
Matched Iupac: … 2-methyl-2,3-dihydro-1,2-thiazol-3-one …
Matched Iupac: … 2-methyl-2,3-dihydro-1,2-thiazol-3-one …
7-[(3-CHLOROBENZYL)OXY]-2-OXO-2H-CHROMENE-4-CARBALDEHYDE
Experimental
Matched Name: … 7-[(3-CHLOROBENZYL)OXY]-2-OXO-2H-CHROMENE-4-CARBALDEHYDE …
Matched Iupac: … 7-[(3-chlorophenyl)methoxy]-2-oxo-2H-chromene-4-carbaldehyde …
Matched Iupac: … 7-[(3-chlorophenyl)methoxy]-2-oxo-2H-chromene-4-carbaldehyde …
Calcium cation
Experimental
Matched Synonyms: … Calcium (2+) ... calcium(2+) ion ... Calcium(2+)ions …
Matched Iupac: … calcium(2+) ion …
Matched Iupac: … calcium(2+) ion …
XmAb24306
XmAb24306 is an investigational cancer immunotherapy. It is a heterodimeric interleukin (IL)-15/IL-15-receptor alpha (IL-15Ra) complex fused to a bispecific Fc domain.
Investigational
1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine
Experimental
Matched Synonyms: … 2-aminoethyl (2R)-2,3-bis(palmitoyloxy)propyl hydrogen phosphate ... 2-aminoethyl (2R)-2,3-bis(hexadecanoyloxy)propyl hydrogen phosphate …
Matched Iupac: … (2-aminoethoxy)[(2R)-2,3-bis(hexadecanoyloxy)propoxy]phosphinic acid …
Matched Iupac: … (2-aminoethoxy)[(2R)-2,3-bis(hexadecanoyloxy)propoxy]phosphinic acid …
RG2417
RG2417 is a proprietary formulation of uridine, a biological compound essential for the synthesis of DNA and RNA, the basic hereditary material found in all cells, and numerous other factors essential for cell metabolism. Uridine is synthesized by the mitochondria, the power plant of the human cell responsible for energy...
Investigational
AT2220
AT2220 is an experimental, oral therapy for the treatment of Pompe disease and belongs to a class of molecules known as pharmacological chaperones. It is a small molecule designed to act as a pharmacological chaperone that specifically binds, stabilizes, and facilitates the proper folding and trafficking of α-glucosidase (GAA). GAA...
Investigational
GSK-2018682
GSK2018682 has been investigated for the treatment of Multiple Sclerosis, Relapsing-Remitting.
Investigational
Matched Iupac: … 4-(4-{5-[5-chloro-6-(propan-2-yloxy)pyridin-3-yl]-1,2,4-oxadiazol-3-yl}-1H-indol-1-yl)butanoic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
GSK-2881078
Investigational
Matched Iupac: … 1-[(2R)-1-methanesulfonylpropan-2-yl]-4-(trifluoromethyl)-1H-indole-5-carbonitrile …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
DT2216
Investigational
Matched Iupac: … piperazin-1-yl}-7-oxoheptanamido)-3,3-dimethylbutanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methyl-1,3-thiazol-5- ... (2S,4R)-1-[(2S)-2-(7-{4-[(3R)-3-{[4-({[4-(4-{[2-(4-chlorophenyl)-5,5-dimethylcyclohex-1-en-1-yl]methyl ... yl)phenyl]ethyl]pyrrolidine-2-carboxamide ... }piperazin-1-yl)phenyl]formamido}sulfonyl)-2-trifluoromethanesulfonylphenyl]amino}-4-(phenylsulfanyl) …
U-0126
U-0126 is a direct inhibitor of the mitogen-activated protein-kinase kinase family members, MEK-1 and MEK-2.
Investigational
Matched Synonyms: … 1,4-diamino-2,3-dicyano-1,4-bis(2-aminophenylthio)butadiene ... Butanedinitrile, bis(amino((2-aminophenyl)thio)methylene)-, (2z,3z)- …
Matched Iupac: … (2Z,3Z)-bis({amino[(2-aminophenyl)sulfanyl]methylidene})butanedinitrile …
Matched Description: … is a direct inhibitor of the mitogen-activated protein-kinase kinase family members, MEK-1 and MEK-2. …
Matched Iupac: … (2Z,3Z)-bis({amino[(2-aminophenyl)sulfanyl]methylidene})butanedinitrile …
Matched Description: … is a direct inhibitor of the mitogen-activated protein-kinase kinase family members, MEK-1 and MEK-2. …
Lactaldehyde
Experimental
Matched Synonyms: … (2s)-2-Hydroxypropanal ... L-2-Hydroxypropionaldehyde …
Matched Iupac: … (2S)-2-hydroxypropanal …
Matched Iupac: … (2S)-2-hydroxypropanal …
(S)-Indapamide
Experimental
Matched Synonyms: … 3-(Aminosulfonyl)-4-chloro-N-((2S)-2,3-dihydro-2-methyl-1H-indol-1-yl)benzamide …
Matched Iupac: … 4-chloro-N-[(2S)-2-methyl-2,3-dihydro-1H-indol-1-yl]-3-sulfamoylbenzamide …
Matched Iupac: … 4-chloro-N-[(2S)-2-methyl-2,3-dihydro-1H-indol-1-yl]-3-sulfamoylbenzamide …
Dacinostat
Dacinostat is a novel histone deacetylase inhibitor.
Investigational
Matched Synonyms: … (2e)-n-hydroxy-3-(4-(((2-hydroxyethyl)(2-(1h-indol-3-yl)ethyl)amino)methyl)phenyl)propenamide …
Matched Iupac: … (2E)-N-hydroxy-3-(4-{[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl}phenyl)prop-2-enamide …
Matched Iupac: … (2E)-N-hydroxy-3-(4-{[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl}phenyl)prop-2-enamide …
GDP-alpha-D-mannuronic acid
Experimental
Matched Iupac: … (2S,3S,4S,5S,6R)-6-({[({[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-3,4-dihydroxyoxolan ... -2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)-3,4,5-trihydroxyoxane-2-carboxylic acid …
Cpad
Experimental
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}[({[(2R,3S,4R,5S)-5-(6-carbamoylpyridin ... -2-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]phosphinic acid …
Adenylosuccinic acid
Experimental
Matched Iupac: … (2S)-2-({9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl]-9H-purin-6-yl}amino)butanedioic …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Rezatapopt
Rezatapopt is under investigation in clinical trial NCT04585750 (The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)).
Investigational
Matched Synonyms: … 4-[[3-[4-[[(3S,4R)-3-Fluoro-1-methyl-4-piperidinyl]amino]-1-(2,2,2-trifluoroethyl)-1H-indol-2-yl]-2-propyn ... yl]-2-propyn-1-yl]amino]-3-methoxy-N-methyl- ... Benzamide, 4-[[3-[4-[[(3S,4R)-3-fluoro-1-methyl-4-piperidinyl]amino]-1-(2,2,2-trifluoroethyl)-1H-indol-2- …
Ro 12-7310
Experimental
D-Tryptophan
Tryptophan is one of the 20 standard amino acids, as well as an essential amino acid in the human diet. It is encoded in the standard genetic code as the codon UGG. The D-stereoisomer is occasionally found in naturally produced peptides (for example, the marine venom peptide contryphan). The distinguishing...
Experimental
Matched Synonyms: … (2R)-2-amino-3-(1H-indol-3-yl)propanoic acid …
Matched Iupac: … (2R)-2-amino-3-(1H-indol-3-yl)propanoic acid …
Matched Iupac: … (2R)-2-amino-3-(1H-indol-3-yl)propanoic acid …
Divarasib
Investigational
Matched Synonyms: … -2-yl)methoxy)quinazolin-4-yl)-3-methylpiperazin-1-yl)prop-2-en-1-one ... -2-(((2S)-1-methyl-2-pyrrolidinyl)methoxy)-4-quinazolinyl)-3-methyl-1-piperazinyl)- ... 1-((3S)-4-((7M)-7-(6-amino-4-methyl-3-(trifluoromethyl)pyridin-2-yl)-6-chloro-8-fluoro-2-(((2S)-1-methylpyrrolidin …
(4s)-4-{[(2s)-2-Amino-3-Oxopropyl]Sulfanyl}-L-Homoserinate
Experimental
Matched Name: … (4s)-4-{[(2s)-2-Amino-3-Oxopropyl]Sulfanyl}-L-Homoserinate …
Matched Iupac: … (2S,4R)-2-amino-4-{[(2R)-2-amino-2-carboxyethyl]sulfanyl}-4-hydroxybutanoic acid …
Matched Iupac: … (2S,4R)-2-amino-4-{[(2R)-2-amino-2-carboxyethyl]sulfanyl}-4-hydroxybutanoic acid …
Displaying drugs 6101 - 6125 of 9359 in total