Displaying drugs 6201 - 6225 of 8179 in total
Xanomeline
Xanomeline is under investigation in clinical trial NCT02831231 (Pilot Study Comparing Effects of Xanomeline Alone to Xanomeline Plus Trospium).
Investigational
Matched Description: … Xanomeline is under investigation in clinical trial NCT02831231 (Pilot Study Comparing Effects of Xanomeline …
BMS-986158
BMS-986158 is under investigation in clinical trial NCT02419417 (Study of BMS-986158 in Subjects With Select Advanced Cancers).
Investigational
Matched Description: … BMS-986158 is under investigation in clinical trial NCT02419417 (Study of BMS-986158 in Subjects With …
Denagliptin
Denagliptin is under investigation in clinical trial NCT00387972 (Study of Denagliptin in Subjects With Type 2 Diabetes Mellitus (T2DM)).
Investigational
Matched Description: … Denagliptin is under investigation in clinical trial NCT00387972 (Study of Denagliptin in Subjects With …
GSK-2981278
GSK-2981278 is under investigation in clinical trial NCT03004846 (A Study of GSK2981278 Ointment in Subjects With Plaque Psoriasis).
Investigational
Matched Description: … GSK-2981278 is under investigation in clinical trial NCT03004846 (A Study of GSK2981278 Ointment in Subjects …
Toralizumab
Toralizumab is under investigation in clinical trial NCT03605927 (CD40-L Blockade for Prevention of Acute Graft-versus-host Disease).
Investigational
Matched Description: … Toralizumab is under investigation in clinical trial NCT03605927 (CD40-L Blockade for Prevention of Acute …
Zagotenemab
Zagotenemab is under investigation in clinical trial NCT03518073 (A Study of LY3303560 in Participants With Early Symptomatic Alzheimer's Disease).
Investigational
Matched Description: … Zagotenemab is under investigation in clinical trial NCT03518073 (A Study of LY3303560 in Participants …
S64315
S64315 (MIK665) is an inhibitor of induced myeloid leukemia cell differentiation protein Myeloid cell leukemia 1 (Mcl-1).
Investigational
Matched Description: … S64315 (MIK665) is an inhibitor of induced myeloid leukemia cell differentiation protein Myeloid cell …
BRG01
BRG01 is a genetically modified autologous CAR-T cell therapy under investigation for the treatment of nasopharyngeal carcinoma.
Investigational
Matched Description: … BRG01 is a genetically modified autologous CAR-T cell therapy under investigation for the treatment of …
CTR-107
CTR-107 is a synthetic targeted growth factor. It is being investigated for the treatment of familial exudative vitreoretinopathy.
Investigational
Matched Description: … It is being investigated for the treatment of familial exudative vitreoretinopathy. …
MaaT013
MaaT013 is an allogeneic fecal microbiota therapy. It is being investigated for the treatment of Graft-Versus-Host Disease.
Investigational
Matched Description: … It is being investigated for the treatment of Graft-Versus-Host Disease. …
TAK-071
TAK-071 is under investigation in clinical trial NCT04334317 (A Study of TAK-071 in People With Parkinson Disease).
Investigational
Matched Description: … TAK-071 is under investigation in clinical trial NCT04334317 (A Study of TAK-071 in People With Parkinson …
Betaprodine
An opioid analgesic chemically related to and with an action resembling that of meperidine, but more rapid in onset and of shorter duration. It has been used in obstetrics, as pre-operative medication, for minor surgical procedures, and for dental procedures. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1067)
Experimental
Illicit
Matched Description: … rapid in onset and of shorter duration. ... An opioid analgesic chemically related to and with an action resembling that of meperidine, but more …
ANX-510
ANX-510 (CoFactor) is a folate-based biomodulator drug being developed to enhance the activity and reduce associated toxicity of the widely used cancer chemotherapy, 5-fluorouracil (5-FU). CoFactor use with 5-FU is being evaluated in clinical trials in first line treatment of metastatic colorectal cancer.
Investigational
Matched Description: … folate-based biomodulator drug being developed to enhance the activity and reduce associated toxicity of ... CoFactor use with 5-FU is being evaluated in clinical trials in first line treatment of metastatic colorectal …
Bisegliptin
Bisegliptin is a compound for the treatment of type 2 diabetes. It is an orally active, dipeptidyl peptidase-IV (DPPIV) inhibitor which lowers blood glucose levels by blocking the degradation of the hormone GLP-1 thereby stimulating glucose-dependent insulin secretion and lowering blood glucose levels without hypoglycemic effects.
Investigational
Matched Description: … Bisegliptin is a compound for the treatment of type 2 diabetes. ... dipeptidyl peptidase-IV (DPPIV) inhibitor which lowers blood glucose levels by blocking the degradation of …
Zilpaterol
Zilpaterol is a β2 adrenergic agonist sold under the trade name, Zilmax, produced by Intervet, a subsidiary of Merck & Co. Zilpaterol is typically fed to cattle in the last three to six weeks of life with a brief washout period to clear the drug from the tissues before slaughter.
Vet approved
Matched Description: … Zilpaterol is a β2 adrenergic agonist sold under the trade name, Zilmax, produced by Intervet, a subsidiary of ... Zilpaterol is typically fed to cattle in the last three to six weeks of life with a brief washout period …
Romifidine
Romifidine is a veterinary drug utilized as a sedative primarily in large animals, most frequently horses. It is also used less commonly in a wide variety of other animal species. This drug's chemical structure closely resembles that of clonidine, however, romifidine is not approved for use in humans.
Vet approved
Matched Description: … It is also used less commonly in a wide variety of other animal species. ... This drug's chemical structure closely resembles that of clonidine, however, romifidine is not approved …
Piroctone
Piroctone olamine is used in combination with other substances as a part of shampoo effectively reduced the amount of dandruff and, at the same time, provided hair conditioning advantages. Recently was shown, that piroctone olamine could induce apoptosis and possessed a significant in vivo effect against myeloma.
Experimental
Matched Description: … the amount of dandruff and, at the same time, provided hair conditioning advantages. ... Piroctone olamine is used in combination with other substances as a part of shampoo effectively reduced …
CY-1503
CY-1503 is a pentasaccharide ethyl glycoside consisting of one alpha-D-sialylosyl residue as a sodium salt, two beta-D-galactopyranosyl residues, one 2-acetamido-beta-Dglucopyranosyl unit, and one alpha-L-fucopyranosyl unit. It was investigated in cardiopulmonary bypass during surgical repair of congenital heart lesions.
Investigational
Matched Description: … CY-1503 is a pentasaccharide ethyl glycoside consisting of one alpha-D-sialylosyl residue as a sodium ... It was investigated in cardiopulmonary bypass during surgical repair of congenital heart lesions. …
SCIB1
SCIB1 is an investigational cancer vaccine being developed by Scancell Ltd. It is being investigated for the treatment of melanoma. It consists of plasmid DNA molecules that express a modified antibody in human cells, working to stimulate the patient's T cells to have a stronger reaction against melanoma cells.
Investigational
Matched Description: … It is being investigated for the treatment of melanoma. ... It consists of plasmid DNA molecules that express a modified antibody in human cells, working to stimulate …
Abivertinib
Abivertinib is a tyrosine kinase inhibitor targeted against mutant forms of both human epidermal growth factor receptor (EGFR) and Bruton's tyrosine kinase (BTK). It has been investigated for use in the treatment of non-small cell lung cancer (NSCLC) and B-cell malignancies. In binding to and inhibiting EGFR and BTK receptors,...
Investigational
Matched Description: … Abivertinib is a tyrosine kinase inhibitor targeted against mutant forms of both human epidermal growth ... [L17383] It has been investigated for use in the treatment of non-small cell lung cancer (NSCLC) and ... BTK receptors, abivertinib exerts immunomodulatory effects by preventing the production and release of …
Taberminogene vadenovec
Taberminogene vadenovec (EG004) is a novel product consisting of a local delivery device and a gene-based medicine, being developed to prevent the blocking of veins and arteries that frequently occurs after vascular surgery. The initial target market is haemodialysis graft access surgery, a procedure in which patients whose kidneys have...
Investigational
Matched Description: … Taberminogene vadenovec (EG004) is a novel product consisting of a local delivery device and a gene-based ... medicine, being developed to prevent the blocking of veins and arteries that frequently occurs after ... EG004 has completed a Phase II trial, this being the first part of the Phase II/III study for which it …
Tandutinib
MLN518 is a novel, oral, small molecule designed to inhibit type III receptor tyrosine kinases, including FLT3, (platelet-derived growth-factor receptor) PDGFR and c-KIT. Tyrosine kinases are enzymes involved in several cellular processes and are known to be activated in cancer cells to drive tumor growth. AML patients with FLT3 mutations...
Investigational
Matched Description: … Approximately 25 to 30 percent of all adult AML patients have a mutation of the FLT3 gene. ... The use of MLN518 to treat AML has been granted fast-track status by the U.S. …
Farletuzumab
Farletuzumab (MORAb-003) is a fully humanized monoclonal antibody against the folate receptor alpha, for the potential treatment of epithelial ovarian cancer.
Investigational
Matched Description: … fully humanized monoclonal antibody against the folate receptor alpha, for the potential treatment of …
Sinapic acid
Sinapic acid is a matrix for matrix-assisted laser desorption technique for protein MW determination. It is also a constituent of propolis.
Experimental
Matched Description: … It is also a constituent of propolis. …
Glyceryl monostearate
Glycerol monostearate, commonly known as GMS, is the glycerol ester of stearic acid . It is commonly used as an emulsifier in foods.
Experimental
Matched Description: … Glycerol monostearate, commonly known as GMS, is the glycerol ester of stearic acid . …
Displaying drugs 6201 - 6225 of 8179 in total