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Displaying drugs 601 - 625 of 3125 in total
Experimental
Matched Synonyms: … Methionine Sulfoxide …
Matched Name: … L-methionine (R)-S-oxide …
Matched Iupac: … (2S)-2-amino-4-[(R)-methanesulfinyl]butanoic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Neutral ... Amino Acids, Sulfur …
Nefazodone hydrochloride (trade name Serzone) is an antidepressant drug marketed by Bristol-Myers Squibb. Its sale was discontinued in 2003 in some countries, due to the small possibility of hepatic (liver) injury. Drug-induced hepatic injuries were associated with an risk of elevated need for a liver transplant, or even death, with...
Approved
Withdrawn
Matched Description: … Nefazodone hydrochloride (trade name Serzone) is an antidepressant drug marketed by Bristol-Myers Squibb ... On May 20, 2004, Bristol-Myers Squibb discontinued the sale of Serzone in the United States. …
Matched Salts name: … Nefazodone hydrochloride
Matched Categories: … Serotonin and Noradrenaline Reuptake Inhibitors ... Serotonin antagonist and reuptake inhibitors (SARIs) …
Matched Products: … Serzone ... Serzone-5ht2 ... Nefazodone hydrochloride
5-methyltetrahydrofolic acid is a methylated derivate of tetrahydrofolate. It is generated by methylenetetrahydrofolate reductase from 5,10-methylenetetrahydrofolate and used to recycle homocysteine back to methionine by 5-methyltetrahydrofolate-homocysteine methyltransferases (also called methionine synthases).
Investigational
Nutraceutical
Matched Synonyms: … 5-Methyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid ... 5-Methyl-5,6,7,8-tetrahydrofolic acid ... N-Methyltetrahydrofolic acid
Matched Name: … 5-methyltetrahydrofolic acid
Matched Iupac: … -amino-5-methyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acid
Matched Description: … It is generated by methylenetetrahydrofolate reductase from 5,10-methylenetetrahydrofolate and used to ... 5-methyltetrahydrofolic acid is a methylated derivate of tetrahydrofolate. ... (also called methionine synthases). …
Matched Categories: … Folic Acid and Derivatives ... Enzymes and Coenzymes …
Oxfenicine in an inhibitor of myocardial metabolism of nonesterified fatty acids (NEFA).
Experimental
Matched Synonyms: … (2S)-Amino(4-Hydroxyphenyl)Acetic Acid ... (S)-(4-hydroxyphenyl)glycine ... L-2-(p-hydroxyphenyl)glycine
Matched Iupac: … (2S)-2-amino-2-(4-hydroxyphenyl)acetic acid
Matched Description: … Oxfenicine in an inhibitor of myocardial metabolism of nonesterified fatty acids (NEFA). …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids
Ioxaglic acid is marketed as Hexabrix. This drug is an ionic tri-iodinated benzoate used as a low-osmolality contrast agent during diagnostic imaging procedures. Like other organic iodine compounds, ioxaglic acid blocks x-rays and is opaque in its appearance on x-ray film, improving the visualization of important structures and organs during...
Approved
Investigational
Matched Synonyms: … Ioxaglic acid ... acido ioxaglico …
Matched Name: … Ioxaglic acid
Matched Iupac: … triiodo-5-(2-{[2,4,6-triiodo-3-(methylcarbamoyl)-5-(N-methylacetamido)phenyl]formamido}acetamido)benzoic acid
Matched Description: … Like other organic iodine compounds, ioxaglic acid blocks x-rays and is opaque in its appearance on x-ray ... Ioxaglic acid has a low osmolarity and is associated with fewer side effects compared to older contrast ... , arthrography, cholangiography, urography, and computed tomography [L1889]. …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... ioxaglic acid ... Triiodobenzoic Acids
Acetrizoic acid presents the molecular formula of 3-acetamidol-2,4,6-triiodobenzoic acid and it is the first monomeric ionic compound used as an X-ray contrast agent. It was first synthesized by Wallingford in 1953 and it was filled in the FDA by the Johnson & Johnson subsidiary, Cilag Chemie AG, on February 8th,...
Withdrawn
Matched Synonyms: … Urokonic acid ... Acide acetrizoique …
Matched Name: … Acetrizoic acid
Matched Iupac: … 3-acetamido-2,4,6-triiodobenzoic acid
Matched Description: … Acetrizoic acid presents the molecular formula of 3-acetamidol-2,4,6-triiodobenzoic acid[L1702] and it ... [A32135] It was first synthesized by Wallingford in 1953[A32136] and it was filled in the FDA by the ... [L1704] Acetrizoic acid presents, in the FDA records, a category of drug substance with an inactive status …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... acetrizoic acid ... Triiodobenzoic Acids
Rulonilimab is under investigation in clinical trial NCT05408221 (The Efficacy and Safety of Rulonilimab in Combination With Lenvatinib in Hepatocellular Carcinoma).
Investigational
Matched Synonyms: … Immunoglobulin g1 (251-glutamine,298-alanine,429-leucine), anti-(human programmed cell death protein …
Matched Description: … Rulonilimab is under investigation in clinical trial NCT05408221 (The Efficacy and Safety of Rulonilimab …
Experimental
Matched Name: … Aspartic Acid-4-Carboxymethyl Ester …
Matched Iupac: … (2S)-2-amino-4-(carboxymethoxy)-4-oxobutanoic acid
Sotigalimab is under investigation in clinical trial NCT03123783 (CD40 Agonistic Antibody APX005M in Combination With Nivolumab).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1 (270-GLUTAMIC ACID, C-TERMINAL-LYSINE-CLIPPED), ANTI-(HUMAN CD40 ANTIGEN) (HUMAN-ORYCTOLAGUS …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients who have undergone prior systemic therapies with limited success. Prognosis is poor and more effective therapies are needed to treat relapsed/refractory cases and improve survival. On April 23 2021, the Food and Drug Administration granted accelerated...
Approved
Investigational
Matched Synonyms: … immunoglobulin G1 antibody directed against human CD19 conjugated to SG3199 through A protease cleavable valine-alanine
Matched Description: … and improve survival. ... Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients ... [A234439] Prognosis is poor and more effective therapies are needed to treat relapsed/refractory cases …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Experimental
Matched Synonyms: … (S)-2-Amino-3-(naphthalen-1-yl)propanoic acid ... Naphthalen-2-yl-3-alanine ... L-beta-(1-Naphthyl)alanine
Matched Name: … 1-Naphthyl-L-alanine
Matched Iupac: … (2S)-2-amino-3-(naphthalen-1-yl)propanoic acid
Selenium is a trace metal in the human body particularly important as a component of glutathione peroxidase, an important enzyme in the prevention of cellular damage by free radicals and reactive oxygen species [FDA Label]
Approved
Investigational
Vet approved
Matched Description: … of glutathione peroxidase, an important enzyme in the prevention of cellular damage by free radicals and
Matched Mixtures name: … Maxine Vitamin and Mineral Supplement ... Henkel's Vitamin E and Selenium Cap ... Rocky Mountain Multiple Vit and Min Mega Tab …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition …
Matched Products: … Selenious Acid
A D-α-amino acid that is the D-isomer of arginine (only the L-form is physiologically active).
Experimental
Matched Synonyms: … D-Arginin ... D-2-Amino-5-guanidinovaleric acid ... (2R)-2-amino-5-guanidinopentanoic acid
Matched Name: … D-arginine
Matched Iupac: … (2R)-2-amino-5-carbamimidamidopentanoic acid
Matched Description: … A D-α-amino acid that is the D-isomer of arginine (only the L-form is physiologically active). …
Clopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and stroke.[A180508,L7213] Clopidogrel is indicated to reduce the risk of myocardial infarction for patients with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and in recent MI, stroke, or established peripheral...
Approved
Matched Iupac: … methyl (2S)-2-(2-chlorophenyl)-2-{4H,5H,6H,7H-thieno[3,2-c]pyridin-5-yl}acetate
Matched Description: … Clopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and ... with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and ... be superior to [aspirin] in reducing cardiovascular outcomes in patients with cardiovascular disease and
Matched Mixtures name: … CLOPIDOGREL E ACIDO ACETILSALICILICO VIATRIS ... CLOPIDOGREL E ACIDO ACETILSALICILICO VIATRIS ... Clopidogrel/acetylsalicylic Acid Mylan …
Matched Salts name: … Clopidogrel hydrochloride
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … CLOPIDOGREL ACINO ... CLOPIDOGREL ACINO PHARMA ... Clopidogrel Acino
Experimental
Matched Name: … Pyridoxyl-Glutamic Acid-5'-Monophosphate …
Prednicarbate is a relatively new topical corticosteroid drug that displays a similar potency as hydrocortisone. It is used in the treatment of inflammatory skin diseases, such as atopic dermatitis. It has a favorable benefit-risk ratio, with an inflammatory action similar to that of a medium potency corticosteroid, but with a...
Approved
Investigational
Matched Description: … IL-1a is also found in fibroblasts, where it is responsible for proliferation, collagenase induction and
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … PREDNICARBAT ACIS CREME ... PREDNICARBAT ACIS SALBE ... PREDNICARBAT ACIS FETTSALB …
Sargramostim is a human recombinant granulocyte macrophage colony-stimulating factor (GM-CSF) expressed in yeast. It is a glycoprotein that is 127 residues. Substitution of Leu23 leads to a difference from native protein.
Approved
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Products: … Leukine
Used as water softener, peptizing agent, emulsifier & dispersing agent; ingredient of cleansers; meat preservative.
Experimental
Matched Synonyms: … acide triphosphorique ... catena-triphosphoric acid ... tripolyphosphoric acid
Matched Name: … Triphosphoric acid
Matched Iupac: … {[hydroxy(phosphonooxy)phosphoryl]oxy}phosphonic acid
Matched Categories: … Acids ... Phosphoric Acids ... Acids, Noncarboxylic ... Phosphorus Acids
A thiol-containing non-essential amino acid that is oxidized to form CYSTINE.
Experimental
Matched Synonyms: … D-Cystein ... (2S)-2-amino-3-mercaptopropanoic acid ... D-Amino-3-mercaptopropionic acid
Matched Name: … D-Cysteine
Matched Iupac: … (2S)-2-amino-3-sulfanylpropanoic acid
Matched Description: … A thiol-containing non-essential amino acid that is oxidized to form CYSTINE. …
Matched Salts name: … D-Cysteine hydrochloride monohydrate …
A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed) Sodium lactate is the sodium salt of lactic acid, and has a mild saline taste. It is produced by fermentation of a sugar source, such as...
Approved
Vet approved
Matched Synonyms: … Milk acid ... Lactic acid ... Acidum lacticum …
Matched Name: … Lactic acid
Matched Iupac: … 2-hydroxypropanoic acid
Matched Description: … (From Stedman, 26th ed) Sodium lactate is the sodium salt of lactic acid, and has a mild saline taste ... It is produced by fermentation of a sugar source, such as corn or beets, and then, by neutralizing the ... resulting lactic acid to create a compound having the formula NaC3H5O3. …
Matched Mixtures name: … Lactic Acid 30% / Salicylic Acid 30% ... Lactic Acid 10% / Urea 40% ... Lactic Acid 10% / Niacinamide 4% …
Matched Categories: … Basic Ointments and Protectants ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Carboxylic Acids ... Hydroxy Acids
Matched Products: … Lactic Acid
ST-101 is a small peptide antagonist of C/EBPβ and T-type calcium channel activator. ST101 has been used in trials studying the treatment of Essential Tremor and Alzheimer's Disease.
Investigational
Matched Synonyms: … ST-101 (D-AMINO ACID PEPTIDE) ... -D-leucyl-D-glutaminyl-D-arginine ... D-Arginine, D-valyl-D-alanyl-D-α-glutamyl-D-alanyl-D-arginyl-D-α-glutamyl-D-α-glutamyl-D-leucyl-D-α-glutamyl-D-arginyl-D-leucyl-D-α-glutamyl-D-alanyl-D-arginyl-D-leucylglycyl-D-glutaminyl-D-alanyl-D-arginylglycyl-D-α-glutamyl-D-leucyl-D-lysyl-D-lys …
Matched Description: … ST-101 is a small peptide antagonist of C/EBPβ and T-type calcium channel activator. ... ST101 has been used in trials studying the treatment of Essential Tremor and Alzheimer's Disease. …
Ezatiostat is investigated in clinical trials for treating myelodysplastic syndrome. This compound belongs to the peptides. These are compounds containing an amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen...
Investigational
Matched Synonyms: … gamma-Glutamyl-S-(benzyl)-cysteinyl-R(-)-phenylglycine diethyl ester …
Matched Description: … These are compounds containing an amide derived from two or more amino carboxylic acid molecules (the ... Ezatiostat has myelostimulant activity in preclinical rodent models and human bone marrow cultures, and ... differentiates granulocytes and monocytes in HL60 cells. …
Matched Salts name: … Ezatiostat hydrochloride
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Synonyms: … L-N2-(2-Carboxyethyl)arginine ... N2-(2-carboxyethyl)arginine ... N2-(2-Carboxyethyl)-L-arginine
Matched Name: … N(2)-(2-carboxyethyl)-L-arginine
Matched Iupac: … (2S)-5-carbamimidamido-2-[(2-carboxyethyl)amino]pentanoic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Basic ... Amino Acids, Diamino …
Domvanalimab is under investigation in clinical trial NCT05502237 (Zimberelimab and Domvanalimab in Combination With Chemotherapy Versus Pembrolizumab With Chemotherapy in Patients With Untreated Metastatic Non-small Cell Lung Cancer).
Investigational
Matched Synonyms: … Immunoglobulin g1 (236-alanine,237-alanine,de-c-terminal-lysine), anti-(human receptor tigit)(human-mus …
Matched Description: … Domvanalimab is under investigation in clinical trial NCT05502237 (Zimberelimab and Domvanalimab in Combination …
PR1 leukemia peptide vaccine is under investigation in clinical trial NCT00513578 (Vaccine Therapy and GM-CSF in Treating Patients With Low-Risk or Intermediate-Risk Myelodysplastic Syndrome).
Investigational
Matched Synonyms: … Nine amino acid polypeptide derived from proteinase 3 ... L-VALINE, L-VALYL-L-LEUCYL-L-GLUTAMINYL-L-.ALPHA. ... -GLUTAMYL-L-LEUCYL-L-ASPARAGINYL-L-VALYL-L-THREONYL- …
Matched Description: … PR1 leukemia peptide vaccine is under investigation in clinical trial NCT00513578 (Vaccine Therapy and
Displaying drugs 601 - 625 of 3125 in total