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Displaying drugs 601 - 625 of 797 in total
Investigational
Matched Synonyms: … 20-mer complementary to Akt mRNA …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Experimental
Matched Name: … Zn(Ii)-(20-Oxo-Protoporphyrin Ix) …
Matched Iupac: … 3-[20-(2-carboxyethyl)-9,14-diethenyl-17-hydroxy-5,10,15,19-tetramethyl-2,22,23,25-tetraaza-1-zincaoctacyclo …
Camptothecin is an alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selectively inhibits the nuclear enzyme DNA topoisomerase, type I. Several semisynthetic analogs of camptothecin have demonstrated antitumor activity.
Experimental
Matched Synonyms: … 20(S)-camptothecine …
Matched Iupac: … -hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0^{2,11}.0^{4,9}.0^{15,20}]henicosa-1(21),2,4,6,8,10,15(20
Investigational
Matched Synonyms: … 5-(2'-hydroxyethoxy)-20(s)-camptothecin …
Matched Iupac: … hydroxyethoxy)-17-oxa-3,13-diazapentacyclo[11.8.0.0^{2,11}.0^{4,9}.0^{15,20}]henicosa-1(21),2,4,6,8,10,15(20
Pegadricase is under investigation in clinical trial NCT01021241 (Safety and Efficacy Study of Intravenous Uricase-PEG 20).
Investigational
Matched Synonyms: … Uricase-PEG 20
Matched Description: … Uricase-PEG 20). ... Pegadricase is under investigation in clinical trial NCT01021241 (Safety and Efficacy Study of Intravenous …
Investigational
Experimental
Matched Iupac: … (5S,18R)-31-oxo-20-oxa-2,6,11,13-tetraazahexacyclo[19.6.2.1^{2,5}.1^{15,19}.0^{9,13}.0^{24,28}]hentriaconta …
A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties. Suramin...
Investigational
Matched Description: … It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with …
Matched Categories: … Agents Against Leishmaniasis and Trypanosomiasis ... Antiparasitic Products, Insecticides and Repellents …
Ripertamab is under investigation in clinical trial NCT02772822 (A Study Comparing the Efficiency and Safety of S-chop(cyclophosphamide, Hydroxydaunomycin, Oncovin, and Prednisone) Versus R-CHOP in Untreated Cd20(cluster of Differentiation Antigen 20)-positive DLBCL Patients).
Investigational
Matched Description: … Cd20(cluster of Differentiation Antigen 20)-positive DLBCL Patients). ... Ripertamab is under investigation in clinical trial NCT02772822 (A Study Comparing the Efficiency and ... Safety of S-chop(cyclophosphamide, Hydroxydaunomycin, Oncovin, and Prednisone) Versus R-CHOP in Untreated …
Investigational
Investigational
Investigational
Matched Iupac: … butoxyethyl)pyridin-1-ium-2-yl]-21,22,23,24-tetraazapentacyclo[16.2.1.1^{3,6}.1^{8,11}.1^{13,16}]tetracosa-1(20
Celastrol is a pentacyclic triterpenoid isolated from the root extracts of Tripterygium wilfordii.
Investigational
Matched Synonyms: … .,20.alpha.)- …
Etynodiol (INN), or ethynodiol (BAN) is a steroidal progestin related to norethisterone which was never marketed. While etynodiol is sometimes used as a synonym for etynodiol diacetate, it usually refers to etynodiol diacetate (see DB00823), not etynodiol.
Experimental
Matched Synonyms: … (3β,17α)-19-Norpregn-4-en-20-yne-3,17-diol …
Matched Categories: … etynodiol and estrogen ... etynodiol and ethinylestradiol ... Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System …
Withdrawn
GP-100 antigen is under investigation in clinical trial NCT00006385 (Vaccine Therapy With or Without Biological Therapy in Treating Patients With Metastatic Melanoma).
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Ocaratuzumab is a humanized monoclonal antibody directed against CD20. It is being investigated for cancers and autoimmune disorders.
Investigational
Matched Description: … It is being investigated for cancers and autoimmune disorders. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … (2'R,3'S)-2'-hydroxy-N-carboxy-3'-amino-5'-methyl-hexanoic,N-tert-butyl ester, 13 ester 5B-20-epoxy-1B …
Experimental
Illicit
Andecaliximab is a monoclonal antibody directed against matrix metallopeptidase 9 (MMP9). Andecaliximab is under investigation in clinical trial NCT03631836 (Phase I Study of Monoclonal Antibondy (GS) 5745, an Matix Metalloproteinase 9 (MMP9) Mab Inhibitor, in Combination With Bevacizumab in Patients With Recurrent Glioblastoma).
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
IFx-Hu2.0 is an investigational cancer vaccine. It is composed of plasmid DNA encoding the streptococcal membrane protein, Emm55, contained within a cationic polymer.
Investigational
Displaying drugs 601 - 625 of 797 in total