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Displaying drugs 6326 - 6350 of 11698 in total

RP-L301

RP-L301 is a lentiviral vector containing the human liver and erythroid pyruvate kinase gene.
Investigational

DNL343

DNL343 is under investigation in clinical trial NCT05842941 (HEALEY ALS Platform Trial - Regimen G DNL343).
Investigational

ACE393

ACE393 is an injectable vaccine designed to combat the bacterium Campylobacter jejuni, one of the greatest causes of bacterial diarrhoeal infections in the developed world.
Investigational

SLV319

SLV319 belongs to a novel class of agents called CB1 antagonists, which work by blocking the cannabinoid type 1 (CB1) receptor. It is developed for the treatment of obesity and other metabolic disorders.
Investigational
Matched Description: … belongs to a novel class of agents called CB1 antagonists, which work by blocking the cannabinoid type 1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

CDP323

CDP323 is an antagonist of the vascular cell adhesion molecule 1 (VCAM-1) binding to alpha4-integrins (other adhesion molecules), a process thought to be implicated in the pathophysiology of Multiple Sclerosis (MS). It is considered a small-molecule prodrug. CDP323 was originally developed by the British biopharmaceutical company Celltech plc. (now UCB...
Investigational
Matched Description: … CDP323 is an antagonist of the _vascular cell adhesion molecule 1_ (VCAM-1) binding to alpha4-integrins …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

IGN301

IGN301 is a cancer vaccine based on an anti-idiotypic antibody which provokes an immune response to Lewis Y. Lewis Y is a carbohydrate molecule expressed on the surface of tumor cells of epithelial origin (e.g. lung, intestinal, breast, prostate or ovarian cancers).
Investigational

ACR325

ACR325 is developed for the treatment of Parkinson’s disease and psychoses, including bipolar disorder, for which disease existing therapies have only limited effect and considerable adverse side effects. ACR325 is a dopaminergic stabiliser, which has demonstrated promising results in disease models for motor functions and psychoses.
Investigational

LY-3039478

LY3039478 has been used in trials studying the treatment and basic science of LYMPHOMA, Neoplasms, Solid Tumor, COLON CANCER, and BREAST CANCER, among others.
Investigational
Matched Iupac: … 4,4,4-trifluoro-N-[(1S)-1-{[(10S)-8-(2-hydroxyethyl)-9-oxo-6,8-diazatricyclo[9.4.0.0^{2,7}]pentadeca- ... 1(15),2,4,6,11,13-hexaen-10-yl]carbamoyl}ethyl]butanamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

LY-3023414

LY3023414 has been used in trials studying the treatment of Neoplasm, Solid Tumor, COLON CANCER, BREAST CANCER, and Advanced Cancer, among others.
Investigational
Matched Iupac: … 8-[5-(2-hydroxypropan-2-yl)pyridin-3-yl]-1-[(2S)-2-methoxypropyl]-3-methyl-1H,2H,3H-imidazo[4,5-c]quinolin ... -2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …

GSK-356278

Gsk356278 has been used in trials studying the treatment and basic science of Anxiety Disorders, Huntington Disease, Depressive Disorder, Huntingtons Disease, and Depressive Disorder, Major, among others.
Investigational
Matched Iupac: … 5-{5-[(2,4-dimethyl-1,3-thiazol-5-yl)methyl]-1,3,4-oxadiazol-2-yl}-1-ethyl-N-(oxan-4-yl)-1H-pyrazolo[ …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Helium He-3

Helium He-3 is under investigation in clinical trial NCT00846014 (Asthma Exacerbation and Helium-3 MRI).
Investigational
Matched Synonyms: … Helium-3 ... Helium, He-3 …
Matched Name: … Helium He-3 …
Matched Description: … Helium He-3 is under investigation in clinical trial NCT00846014 (Asthma Exacerbation and Helium-3 MRI …

SEP-363856

SEP-363856 is a novel psychotropic drug being investigated for the treatment of schizophrenia. Unlike other drugs used for this condition, SEP-363856 does not bind to the dopamine D2 receptors, but exerts actions on the trace amine–associated receptor 1 (TAAR1) and 5-hydroxytryptamine type 1A (5-HT1A). SEP-363856 was developed by Sunovion pharmaceuticals....
Investigational
Matched Iupac: … methyl({[(7S)-4H,5H,7H-thieno[2,3-c]pyran-7-yl]methyl})amine …
Matched Description: … (TAAR1) and 5-hydroxytryptamine type 1A (5-HT1A). ... does not bind to the dopamine D2 receptors, but exerts actions on the trace amine–associated receptor 1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

CSL324

CSL324 is a fully human anti-G-CSFR antibody shown to have the ability to control G-CSF-mediated neutrophilia in cynomolgus macaques. It has potential applications in various inflammatory conditions such as cystic fibrosis, inflammatory bowel disease, rheumatoid arthritis, and vasculitis.
Investigational

ARO-APOC3

ARO-APOC3 is an investigational RNAi therapeutic targeting apolipoprotein C-III (APOC3). It received an Orphan Drug designation by the FDA for the treatment of familial chylomicronemia syndrome.
Investigational

SPG302

Investigational
Matched Synonyms: … 2-(2-(2-(2-(4-benzothiazol-2-y1-phenoxy)-ethoxy)-ethoxy)-ethoxy)-ethanol ... Ethanol, 2-(2-(2-(2-(4-(2-benzothiazolyl)phenoxy)ethoxy)ethoxy)ethoxy)- …
Matched Iupac: … 2-[2-(2-{2-[4-(1,3-benzothiazol-2-yl)phenoxy]ethoxy}ethoxy)ethoxy]ethan-1-ol …

AAV-CNGB3

AAV-CNGB3 is an adenovirus associated viral vector serotype 8 containing the human CNGB3 gene.
Investigational

Vepsitamab

Investigational
Matched Synonyms: … BISPECIFIC, ANTI-(HUMAN MUCIN 17) (HUMAN MONOCLONAL MUC17_CD3_ALT2 SINGLE-CHAIN VARIABLE FRAGMENT VH1-(GGGGS)3- …

Vinylglycine

Vinylglycine is an irreversible inhibitor of aspartate aminotransferase.
Experimental
Matched Synonyms: … (2S)-2-amino-3-butenoic acid …
Matched Iupac: … (2S)-2-aminobut-3-enoic acid …

2-Anhydro-3-Fluoro-Quinic Acid

Experimental
Matched Name: … 2-Anhydro-3-Fluoro-Quinic Acid …
Matched Iupac: … (1R,4S,5R)-3-fluoro-1,4,5-trihydroxycyclohex-2-ene-1-carboxylic acid …

8-Benzyl-2-Hydroxy-2-(4-Hydroxy-Benzyl)-6-(4-Hydroxy-Phenyl)-2h-Imidazo[1,2-a]Pyrazin-3-One

Experimental
Matched Name: … 8-Benzyl-2-Hydroxy-2-(4-Hydroxy-Benzyl)-6-(4-Hydroxy-Phenyl)-2h-Imidazo[1,2-a]Pyrazin-3-One …
Matched Iupac: … (2S)-8-benzyl-2-hydroxy-6-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl)methyl]-2H,3H-imidazo[1,2-a]pyrazin-3 …

1,2-Hexanediol

Experimental

1alpha-Hydroxyvitamin D5

1alpha-Hydroxyvitamin D5 (CARD-024) has been used in trials studying the treatment of Drug Safety and Heart; Disease, Activity.
Investigational
Matched Synonyms: … 1-Hydroxyvitamin D5 …
Matched Iupac: … (1R,3S,5Z)-5-{2-[(1R,3aS,4E,7aR)-1-[(2R,5R)-5-ethyl-6-methylheptan-2-yl]-7a-methyl-octahydro-1H-inden ... -4-ylidene]ethylidene}-4-methylidenecyclohexane-1,3-diol …

3-Tyrosine

Experimental
Matched Synonyms: … 3-Hydroxyphenylalanine ... 3-(m-Hydroxyphenyl)alanine ... 3-Hydroxy-L-phenylalanine …
Matched Name: … 3-Tyrosine …
Matched Iupac: … (2S)-2-amino-3-(3-hydroxyphenyl)propanoic acid …

ZYC300

ZYC300 is a plasmid DNA of CYP1B1 encapsulated in biodegradable poly-DL-lactide-coglycolide microparticles. It is designed as a vaccine, intended to increase immune system sensitivity to CYP1B1, an enzyme highly prevalent in tumor cells.
Investigational

IGN311

IGN311 is a humanized monoclonal antibody (mab) against the Lewis Y carbohydrate antigen, a blood-group-related oligosaccharide.
Investigational
Displaying drugs 6326 - 6350 of 11698 in total