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Displaying drugs 6426 - 6450 of 11083 in total

SEP-363856

SEP-363856 is a novel psychotropic drug being investigated for the treatment of schizophrenia. Unlike other drugs used for this condition, SEP-363856 does not bind to the dopamine D2 receptors, but exerts actions on the trace amine–associated receptor 1 (TAAR1) and 5-hydroxytryptamine type 1A (5-HT1A). SEP-363856 was developed by Sunovion pharmaceuticals....
Investigational
Matched Description: … (TAAR1) and 5-hydroxytryptamine type 1A (5-HT1A). ... does not bind to the dopamine D2 receptors, but exerts actions on the trace amine–associated receptor 1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

8-(2,5-Dimethoxy-Benzyl)-2-Fluoro-9h-Purin-6-Ylamine

Experimental
Matched Name: … 8-(2,5-Dimethoxy-Benzyl)-2-Fluoro-9h-Purin-6-Ylamine …
Matched Iupac: … 8-[(2,5-dimethoxyphenyl)methyl]-2-fluoro-7H-purin-6-amine …

(2S)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-3-(pentafluorophenoxy)propanamide

Experimental
Matched Name: … (2S)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-3-(pentafluorophenoxy)propanamide …
Matched Iupac: … (2S)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-3-(2,3,4,5,6-pentafluorophenoxy)propanamide …

4-Methyl-1,2-Benzenediol

Experimental

3-(Benzyloxy)Pyridin-2-Amine

Experimental
Matched Name: … 3-(Benzyloxy)Pyridin-2-Amine …
Matched Iupac: … 3-(benzyloxy)pyridin-2-amine …

2,3-di-O-phytanyl-sn-glycerol

Experimental
Matched Iupac: … (2R)-2,3-bis({[(3R,7R,11R)-3,7,11,15-tetramethylhexadecyl]oxy})propan-1-ol …

2,2-Dichloro-1-methanesulfinyl-3-methyl-cyclopropanecarboxylic acid [1-(4-bromo-phenyl)-ethyl]-amide

Experimental
Matched Name: … 2,2-Dichloro-1-methanesulfinyl-3-methyl-cyclopropanecarboxylic acid [1-(4-bromo-phenyl)-ethyl]-amide …
Matched Iupac: … (1R,3R)-N-[1-(4-bromophenyl)ethyl]-2,2-dichloro-1-[(S)-methanesulfinyl]-3-methylcyclopropane-1-carboxamide …

Tridolgosir

An indolizidine alkaloid from the plant Swainsona canescens that is a potent alpha-mannosidase inhibitor. Swainsonine also exhibits antimetastatic, antiproliferative, and immunomodulatory activity.
Experimental

Cinpanemab

Cinpanemab is under investigation in clinical trial NCT03318523 (Evaluating the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of BIIB054 in Participants With Parkinson's Disease).
Investigational
Matched Synonyms: … chain (1-442) (homo sapiens vh (ighv3-25*03 (86%) (ighd)-ighj2*01) (8.10.4) (1-113)-homo sapiens ighg1 ... Immunoglobulin g1-lambda, anti-(homo sapiens alpha-synuclein)humanized monoclonal antibody.gamma.1 heavy ... lewy body) 4, non a4 component of amyloid precursor, nacp)), monoclonal antibodygamma1 heavy chain (1- …

Coumarin

Experimental
Matched Synonyms: … 2H-1-benzopyran-2-one ... 2H-benzo(b)pyran-2-one …
Matched Iupac: … 2H-chromen-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …

(2R)-N-hydroxy-3-naphthalen-2-yl-2-[(naphthalen-2-ylsulfonyl)amino]propanamide

Experimental
Matched Name: … (2R)-N-hydroxy-3-naphthalen-2-yl-2-[(naphthalen-2-ylsulfonyl)amino]propanamide …
Matched Iupac: … (2R)-N-hydroxy-3-(naphthalen-2-yl)-2-(naphthalene-2-sulfonamido)propanamide …

1-CYCLOHEXYL-N-{[1-(4-METHYLPHENYL)-1H-INDOL-3-YL]METHYL}METHANAMINE

Experimental
Matched Name: … 1-CYCLOHEXYL-N-{[1-(4-METHYLPHENYL)-1H-INDOL-3-YL]METHYL}METHANAMINE …
Matched Iupac: … (cyclohexylmethyl)({[1-(4-methylphenyl)-1H-indol-3-yl]methyl})amine …

(2E)-3-(4-CHLOROPHENYL)-N-HYDROXYACRYLAMIDE

Experimental
Matched Name: … (2E)-3-(4-CHLOROPHENYL)-N-HYDROXYACRYLAMIDE …
Matched Iupac: … (2E)-3-(4-chlorophenyl)-N-hydroxyprop-2-enamide …

Recombinant Bacterial ACE2 Receptors-like Enzyme

B38-CAP is structured as a carboxypeptidase and derived from Paenibacillus sp. The molecule, an Angiotensin Converting Enzyme 2 (ACE2)-like enzyme, shares structural similarities to the mammalian ACE2. B38-CAP is an ACE2-like enzyme which decreases angiotensin II levels. It is being investigated for treating hypertension, myocardial fibrosis, and cardiac dysfunction.
Investigational
Matched Description: … ._ The molecule, an Angiotensin Converting Enzyme 2 (ACE2)-like enzyme, shares structural similarities …

Olenasufligene relduparvovec

Olenasufligene relduparvovec is under investigation in clinical trial NCT03612869 (Study of aavrh10-h.sgsh Gene Therapy in Patients With Mucopolysaccharidosis Type IIIA (MPS IIIA)). It is an adeno-associated virus (AAV) vector that delivers a functional copy of the human SGSH gene.
Investigational
Matched Synonyms: … Dna (recombinant adeno-associated virus 2 vector lys-saf302 human n-sulfoglucosamine sulfohydrolase cdna-specifying …

ABO-201

Investigational

JBI-802

Investigational
Matched Synonyms: … N-hydroxy-4-((4-((((1R,2S)-2-phenylcyclopropyl) amino)methyl)-1H-pyrazol-1-yl)methyl)benzamide hydrogen …

8-(2-Chloro-3,4,5-Trimethoxy-Benzyl)-9-Pent-4-Ylnyl-9h-Purin-6-Ylamine

Experimental
Matched Name: … 8-(2-Chloro-3,4,5-Trimethoxy-Benzyl)-9-Pent-4-Ylnyl-9h-Purin-6-Ylamine …
Matched Iupac: … 8-[(2-chloro-3,4,5-trimethoxyphenyl)methyl]-9-(pent-4-yn-1-yl)-9H-purin-6-amine …

4-[3-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]PYRIDINE

Experimental
Matched Name: … 4-[3-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]PYRIDINE …
Matched Iupac: … 4-[3-(4-fluorophenyl)-1H-pyrazol-4-yl]pyridine …

(+)-2-(4-biphenyl)propionic acid

Experimental
Matched Synonyms: … (2S)-2-(4-Biphenylyl)propanoic acid ... 2-(1,1'-biphenyl-4-yl)propanoic acid …
Matched Name: … (+)-2-(4-biphenyl)propionic acid …
Matched Iupac: … (2S)-2-{[1,1'-biphenyl]-4-yl}propanoic acid …

Kaempherol

Experimental
Matched Iupac: … 3,5,7-trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one …

Quercetin-3'-O-phosphate

Quercetin-3'-O-phosphate has been used in trials studying the treatment of Insulin Resistance and Impaired Glucose Tolerance.
Investigational
Matched Name: … Quercetin-3'-O-phosphate …
Matched Iupac: … [2-hydroxy-5-(3,5,7-trihydroxy-4-oxo-4H-chromen-2-yl)phenoxy]phosphonic acid …
Matched Description: … Quercetin-3'-O-phosphate has been used in trials studying the treatment of Insulin Resistance and Impaired …

Amlitelimab

Amlitelimab is under investigation in clinical trial NCT06181435 (A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis (COAST 2)).
Investigational
Matched Description: … With Placebo in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis (COAST 2) …

2,3-Difluorobenzyl Alcohol

Experimental

Zanidatamab

According to Zymeworks, "ZW25 is a bispecific antibody that can simultaneously bind two non-overlapping epitopes, known as biparatopic binding, of HER2 resulting in dual HER2 signal blockade, increased binding and removal of HER2 protein from the cell surface, and potent effector function. These combined mechanisms of action have led to...
Investigational
Matched Synonyms: … KINASE ERBB-2, EGFR2, HER2, HER-2, P185C-ERBB2, NEU, CD340)), HUMANIZED MONOCLONAL ANTIBODY, BIPARATOPIC ... IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS ERBB2 (EPIDERMAL GROWTH FACTOR RECEPTOR 2, RECEPTOR TYROSINEPROTEIN …
Displaying drugs 6426 - 6450 of 11083 in total