Displaying drugs 626 - 650 of 10948 in total
Vildagliptin
Vildagliptin (LAF237) is an orally active antihyperglycemic agent that selectively inhibits the dipeptidyl peptidase-4 (DPP-4) enzyme. It is used to manage type II diabetes mellitus, where GLP-1 secretion and insulinotropic effects are impaired. By inhibiting DPP-4, vildagliptin prevents the degradation of glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP),...
Approved
Investigational
Matched Description: … of type II diabetes mellitus in adults as monotherapy or in combination with [metformin], a sulfonylurea ... Elevated levels of GLP-1 and GIP consequently results in improved glycemic control. ... [L32803] In clinical trials, vildagliptin has a relatively low risk of hypoglycemia. …
Matched Categories: … Drugs Used in Diabetes …
Matched Categories: … Drugs Used in Diabetes …
Casein
Casein allergenic extract is used in allergenic testing.
Approved
Matched Description: … Casein allergenic extract is used in allergenic testing. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Padeliporfin
Padeliporfin is a water-soluble chlorophyll derivative and cytotoxic photosensitizer used for vascular-targeted photodynamic therapy for malignancies. Vascular-targeted photodynamic therapy (VTP), or vascular targeted photochemotherapy, is a focal treatment for localized prostate cancer. It aims to destroy only cancerous lesions of the prostate, rather than ablating the entire prostate gland. Padeliporfin...
Approved
Experimental
Matched Description: … low-risk prostate cancer in adults meeting certain clinical criteria. ... Padeliporfin was first approved by the European Commission on November 10, 2017, for the treatment of ... It aims to destroy only cancerous lesions of the prostate, rather than ablating the entire prostate gland …
Matched Categories: … Sensitizers Used in Photodynamic/radiation Therapy …
Matched Categories: … Sensitizers Used in Photodynamic/radiation Therapy …
Edetic acid
A chelating agent (chelating agents) that sequesters a variety of polyvalent cations. It is used in pharmaceutical manufacturing and as a food additive.
Approved
Vet approved
Matched Description: … It is used in pharmaceutical manufacturing and as a food additive. ... A chelating agent (chelating agents) that sequesters a variety of polyvalent cations. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Ruxolitinib
Ruxolitinib, formerly known as INCB018424 or INC424, is an anticancer drug and a Janus kinase (JAK) inhibitor. It is a potent and selective inhibitor of JAK1 and JAK2, which are tyrosine kinases involved in cytokine signalling and hematopoiesis. Myeloproliferative neoplasms, such as myelofibrosis and polycythemia vera, are often characterized by...
Approved
Matched Description: … [A229708] In 2014, it was approved for the treatment of polycythemia vera in adults who have an inadequate ... response to or are intolerant of [hydroxyurea] and in 2019, ruxolitinib was approved for use in steroid-refractory ... the FDA in 2011, followed by EMA's approval in 2012. …
Matched Salts cas: … 1092939-17-7 …
Matched Salts cas: … 1092939-17-7 …
Isoniazid
Antibacterial agent used primarily as a tuberculostatic. It remains the treatment of choice for tuberculosis.
Approved
Investigational
Matched Description: … It remains the treatment of choice for tuberculosis. …
Matched Categories: … Drugs for Treatment of Tuberculosis ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Drugs for Treatment of Tuberculosis ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Influenza A virus A/Singapore/gp1908/2015 IVR-180 (H1N1) hemagglutinin antigen (MDCK cell derived, propiolactone inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated ... Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised …
Potassium acetate
Approved
Investigational
Matched Mixtures name: … Numeta G 13 % E Emulsion zur Infusion …
Acetic acid
Acetic acid is a product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed) Acetic acid otic (for the ear) is an antibiotic that treats infections caused by bacteria or...
Approved
Matched Description: … Acetic acid is a product of the oxidation of ethanol and of the destructive distillation of wood. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Scorpion (centruroides) immune Fab2 antivenin (equine)
Centruroides (scorpion) Immune F(ab')2 (equine) is a purified preparation of immune globulin F(ab’)2 fragments that are derived from plasma of the horses immunized with venom of C. noxius, C. l. limpidus, C. l. tecomanus, and C. s. suffusus. It is intravenously administered patients with clinical signs of scorpion envenomation so...
Approved
Matched Description: … Because initial development and use of this product in Mexico, venoms from several Centruroides species ... and hospitalization in an intensive care unit. ... fragments that are derived from plasma of the horses immunized with venom of *C. noxius*, *C. l. limpidus …
Penicillamine
Penicillamine is a pharmaceutical of the chelator class. The pharmaceutical form is D-penicillamine, as L-penicillamine is toxic (it inhibits the action of pyridoxine). It is an α-amino acid metabolite of penicillin, although it has no antibiotic properties.
Approved
Matched Description: … Penicillamine is a pharmaceutical of the chelator class. ... It is an α-amino acid metabolite of penicillin, although it has no antibiotic properties. ... The pharmaceutical form is D-penicillamine, as L-penicillamine is toxic (it inhibits the action of pyridoxine …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Dibenzepin
Dibenzepin is approved for use in Europe.
Approved
Matched Description: … Dibenzepin is approved for use in Europe. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Hydroxocobalamin
Hydroxocobalamin, also known as vitamin B12a and hydroxycobalamin, is an injectable form of vitamin B 12 that has been used therapeutically to treat vitamin B 12 deficiency. It is also used in cyanide poisoning, Leber's optic atrophy, and toxic amblyopia.
Approved
Matched Description: … It is also used in cyanide poisoning, Leber's optic atrophy, and toxic amblyopia. ... Hydroxocobalamin, also known as vitamin B12a and hydroxycobalamin, is an injectable form of vitamin B …
Plicamycin
Plicamycin is an antineoplastic antibiotic produced by Streptomyces plicatus. It has been used in the treatment of testicular cancer, Paget's disease of bone, and, rarely, the management of hypercalcemia. The manufacturer discontinued plicamycin in 2000.
Approved
Investigational
Withdrawn
Matched Iupac: … {[(2S,4R,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy}-5-hydroxy-6-methyloxan-2-yl]oxy}-8,9-dihydroxy-7- …
Matched Description: … It has been used in the treatment of testicular cancer, Paget's disease of bone, and, rarely, the management ... The manufacturer discontinued plicamycin in 2000. ... of hypercalcemia. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Description: … It has been used in the treatment of testicular cancer, Paget's disease of bone, and, rarely, the management ... The manufacturer discontinued plicamycin in 2000. ... of hypercalcemia. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Karaya gum
Karaya gum allergenic extract is used in allergenic testing.
Approved
Matched Description: … Karaya gum allergenic extract is used in allergenic testing. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Bordetella pertussis toxoid antigen (glutaraldehyde inactivated)
Approved
Investigational
Influenza A virus A/Kansas/14/2017 (H3N2) live (attenuated) antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated ... Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised …
Sulfathiazole
Sulfathiazole is a short-acting sulfa drug. It used to be a common oral and topical antimicrobial until less toxic alternatives were discovered. It is still occasionally used, sometimes in combination with sulfabenzamide and sulfacetamide.
Except for those formulated for vaginal use, the FDA withdrew its approval for the use of...
Approved
Vet approved
Withdrawn
Matched Description: … It is still occasionally used, sometimes in combination with sulfabenzamide and sulfacetamide. ... Except for those formulated for vaginal use, the FDA withdrew its approval for the use of all drug products …
Matched Categories: … combinations of sulfonamides …
Matched Categories: … combinations of sulfonamides …
Sulfameter
Long acting sulfonamide used in leprosy, urinary, and respiratory tract infections.
Approved
Matched Description: … Long acting sulfonamide used in leprosy, urinary, and respiratory tract infections. …
Matched Categories: … combinations of sulfonamides …
Matched Categories: … combinations of sulfonamides …
Clomifene
A triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue.
Approved
Investigational
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Etacrynic acid
A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop...
Approved
Investigational
Matched Description: … A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of ... This pharmacological action results in excretion of these ions, increased urinary output, and reduction ... in extracellular fluid. …
Matched Categories: … Increased Diuresis at Loop of Henle …
Matched Categories: … Increased Diuresis at Loop of Henle …
Chorionic Gonadotropin (Human)
Human chorionic gonadotropin (HCG), a polypeptide hormone produced by the human placenta. Endogenously produced HCG interacts with the LHCG receptor of the ovary and promotes the maintenance of the corpus luteum during the beginning of pregnancy. This allows the corpus luteum to continuously secrete the hormone progesterone during the first...
Approved
Vet approved
Matched Description: … human thyroid-stimulating hormone (TSH), while the beta sub units of these hormones differ in amino ... In males, HCG also stimulates the production of gonadal steroid hormones by stimulating the interstitial ... of the corpus luteum during the beginning of pregnancy. …
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Displaying drugs 626 - 650 of 10948 in total