Displaying drugs 626 - 650 of 2924 in total
Aminopterin
Aminopterin is an amino derivative of folic acid, which was once used as an antineoplastic agent in the treatment of pediatric leukemia. In the 1950's its production was discontinued in favor of methotrexate, which is less potent but less toxic. Off label, aminopterin has also been used in the treatment...
Investigational
Withdrawn
Matched Synonyms: … N-(4-(((2,4-diamino-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid ... 4-aminofolic acid ... 4-aminopteroylglutamic acid …
Matched Iupac: … (2S)-2-[(4-{[(2,4-diaminopteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acid …
Matched Description: … Clinicians need to be aware of the characteristic teratologic effects of aminopterin and methotrexate ... Aminopterin is an amino derivative of folic acid, which was once used as an antineoplastic agent in the …
Matched Categories: … Folic Acid Antagonists …
Matched Iupac: … (2S)-2-[(4-{[(2,4-diaminopteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acid …
Matched Description: … Clinicians need to be aware of the characteristic teratologic effects of aminopterin and methotrexate ... Aminopterin is an amino derivative of folic acid, which was once used as an antineoplastic agent in the …
Matched Categories: … Folic Acid Antagonists …
Abiraterone
Abiraterone is a potent, irreversible, and selective inhibitor of 17 αhydroxylase/C17,20-lyase (CYP17), an enzyme expressed in testicular, adrenal, and prostatic tumour tissues, to regulate androgen biosynthesis.[A3811, A260880, L40968] Abiraterone was first approved by the FDA and EMA on April, July, and September 2011, respectively. It is used to treat metastatic...
Approved
Matched Description: … hydrolysis by esterases, abiraterone acetate was developed as an orally bioavailable prodrug with enhanced ... Abiraterone is a potent, irreversible, and selective inhibitor of 17 αhydroxylase/C17,20-lyase (CYP17 ... ] and September 2011,[A260880] respectively. …
Matched Salts name: … Abiraterone acetate …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... niraparib and abiraterone ... abiraterone and prednisolone ... Hormone Antagonists and Related Agents ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … Abiraterone Acetate ... Abiraterone acetate ... Abiratred Abiraterone Acetate Tablets 250mg …
Matched Salts name: … Abiraterone acetate …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... niraparib and abiraterone ... abiraterone and prednisolone ... Hormone Antagonists and Related Agents ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … Abiraterone Acetate ... Abiraterone acetate ... Abiratred Abiraterone Acetate Tablets 250mg …
Betaine
Betaine is a methyl group donor that functions in the normal metabolic cycle of methionine. It is a naturally occurring choline derivative commonly ingested through diet, with a role in regulating cellular hydration and maintaining cell function.[A252235,A252240] Homocystinuria is an inherited disorder that leads to the accumulation of homocysteine in...
Approved
Investigational
Nutraceutical
Matched Synonyms: … Acidol ... Glycine betaine ... 2-(Trimethylammonio)Acetate …
Matched Iupac: … 2-(trimethylazaniumyl)acetate …
Matched Description: … occurring choline derivative commonly ingested through diet, with a role in regulating cellular hydration and ... A252240] Homocystinuria is an inherited disorder that leads to the accumulation of homocysteine in plasma and ... levels, patients can be treated with vitamin B6 ([pyridoxine]), vitamin B12 ([cobalamin]), [folate] and …
Matched Mixtures name: … Glutamic Acid Pepsin and Betaine Tablets ... Glutamic Acid HCl Betaine HCl W Pepsin ... Betaine HCl and Pepsin …
Matched Categories: … Amino Acids and Derivatives ... Alimentary Tract and Metabolism ... Acid Preparations …
Matched Iupac: … 2-(trimethylazaniumyl)acetate …
Matched Description: … occurring choline derivative commonly ingested through diet, with a role in regulating cellular hydration and ... A252240] Homocystinuria is an inherited disorder that leads to the accumulation of homocysteine in plasma and ... levels, patients can be treated with vitamin B6 ([pyridoxine]), vitamin B12 ([cobalamin]), [folate] and …
Matched Mixtures name: … Glutamic Acid Pepsin and Betaine Tablets ... Glutamic Acid HCl Betaine HCl W Pepsin ... Betaine HCl and Pepsin …
Matched Categories: … Amino Acids and Derivatives ... Alimentary Tract and Metabolism ... Acid Preparations …
(6R)-Folinic acid
Experimental
Matched Synonyms: … L-Glutamic acid, N-[4-[[[(6R)-2-amino-5-formyl-3,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl]methyl]amino] ... acid ... (6R,2'S)-Folinic acid …
Matched Name: … (6R)-Folinic acid …
Matched Iupac: … -amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido}pentanedioic acid …
Matched Categories: … Folic Acid and Derivatives …
Matched Name: … (6R)-Folinic acid …
Matched Iupac: … -amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido}pentanedioic acid …
Matched Categories: … Folic Acid and Derivatives …
Pantothenyl-Aminoethanol-Acetate Pivalic Acid
Experimental
Matched Name: … Pantothenyl-Aminoethanol-Acetate Pivalic Acid …
Calcium gluconate
Calcium gluconate is used as mineral supplement and medication when there is insufficient calcium in the diet. Supplementation may be done to treat or prevent osteoporosis or rickets, consequences of hypocalcemia. It can also be taken by mouth but is not recommended by injection into a muscle.
Calcium Gluconate Injection,...
Approved
Vet approved
Matched Synonyms: … D-gluconic acid, calcium salt (2:1) …
Matched Description: … Hydrochloric acid and/or sodium hydroxide may have been added for pH adjustment (6.0 to 8.2). ... Calcium gluconate is used as mineral supplement and medication when there is insufficient calcium in ... Calcium saccharate provides 6% of the total calcium and stabilizes the supersaturated solution of calcium …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Acids, Acyclic ... Sugar Acids …
Matched Products: … HYDROFLUORIC ACID ANTIDOTE GEL 2.5% w/w …
Matched Description: … Hydrochloric acid and/or sodium hydroxide may have been added for pH adjustment (6.0 to 8.2). ... Calcium gluconate is used as mineral supplement and medication when there is insufficient calcium in ... Calcium saccharate provides 6% of the total calcium and stabilizes the supersaturated solution of calcium …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Acids, Acyclic ... Sugar Acids …
Matched Products: … HYDROFLUORIC ACID ANTIDOTE GEL 2.5% w/w …
Arginine PCA
Experimental
Matched Synonyms: … Arginine pidolate ... Arginine pyroglutamate ... L-arginine L-2-pyrrolidone-5-carboxylate …
Matched Name: … Arginine PCA …
Matched Iupac: … (2S)-2-amino-5-carbamimidamidopentanoic acid; (2S)-5-oxopyrrolidine-2-carboxylic acid …
Matched Name: … Arginine PCA …
Matched Iupac: … (2S)-2-amino-5-carbamimidamidopentanoic acid; (2S)-5-oxopyrrolidine-2-carboxylic acid …
Linoleic acid
Approved
Experimental
Matched Synonyms: … Linolic acid ... acide linoléique ... acide cis-linoléique …
Matched Name: … Linoleic acid …
Matched Iupac: … (9Z,12Z)-octadeca-9,12-dienoic acid …
Matched Categories: … Fatty Acids ... Linoleic Acids ... Fatty Acids, Omega-6 ... Fatty Acids, Essential ... Fatty Acids, Unsaturated …
Matched Name: … Linoleic acid …
Matched Iupac: … (9Z,12Z)-octadeca-9,12-dienoic acid …
Matched Categories: … Fatty Acids ... Linoleic Acids ... Fatty Acids, Omega-6 ... Fatty Acids, Essential ... Fatty Acids, Unsaturated …
Levoleucovorin
Levoleucovorin is the enantiomerically active form of Folinic Acid (also known as 5-formyl tetrahydrofolic acid or leucovorin). Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary isomers, while levoleucovorin contains only the pharmacologically active levo-isomer. In vitro, the levo-isomer has been shown to be...
Approved
Investigational
Matched Synonyms: … N-[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic ... acid ... L-Folinic acid …
Matched Iupac: … -amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido}pentanedioic acid …
Matched Description: … and methionine before incorporation into DNA or protein. ... This important pathway, which is required for de novo synthesis of nucleic acids and amino acids, is ... acid or leucovorin). …
Matched Categories: … Folic Acid and Derivatives ... Enzymes and Coenzymes ... Folic Acid Analogues …
Matched Iupac: … -amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido}pentanedioic acid …
Matched Description: … and methionine before incorporation into DNA or protein. ... This important pathway, which is required for de novo synthesis of nucleic acids and amino acids, is ... acid or leucovorin). …
Matched Categories: … Folic Acid and Derivatives ... Enzymes and Coenzymes ... Folic Acid Analogues …
Fumaric acid
Investigational
Matched Synonyms: … Fumaric acid ... Fumaricum acidum ... (2E)-2-butenedioic acid …
Matched Name: … Fumaric acid …
Matched Iupac: … (2E)-but-2-enedioic acid …
Matched Categories: … Acids, Acyclic ... fumaric acid ... Carboxylic Acids ... Dicarboxylic Acids …
Matched Name: … Fumaric acid …
Matched Iupac: … (2E)-but-2-enedioic acid …
Matched Categories: … Acids, Acyclic ... fumaric acid ... Carboxylic Acids ... Dicarboxylic Acids …
Para-Iodo-D-Phenylalanine Hydroxamic Acid
Experimental
Matched Name: … Para-Iodo-D-Phenylalanine Hydroxamic Acid …
Diphthamide
Experimental
Matched Synonyms: … 2-(3-Carboxyamido-3-(Trimethylammonio)Propyl)Histidine …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic …
3-nitro-L-tyrosine
Experimental
Matched Synonyms: … (2S)-2-amino-3-(4-hydroxy-3-nitrophenyl)propanoic acid ... 3-Nitro-L-tyrosine …
Matched Name: … 3-nitro-L-tyrosine …
Matched Iupac: … (2S)-2-amino-3-(4-hydroxy-3-nitrophenyl)propanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Matched Name: … 3-nitro-L-tyrosine …
Matched Iupac: … (2S)-2-amino-3-(4-hydroxy-3-nitrophenyl)propanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Folitixorin
Investigational
Matched Synonyms: … L-glutamic acid, n-(4-(3-amino-1,2,5,6,6a,7-hexahydro-1-oxoimidazo(1,5-f)pteridin-8(9h)-yl)benzoyl)- ... 5,10-methylene-(6rs)-tetrahydrofolic acid ... 5,10-methylenetetrahydrofolic acid …
Matched Iupac: … 4-{3-amino-1-oxo-1H,2H,5H,6H,6aH,7H,8H,9H-imidazo[1,5-f]pteridin-8-yl}phenyl)formamido]pentanedioic acid …
Matched Categories: … Enzymes and Coenzymes …
Matched Iupac: … 4-{3-amino-1-oxo-1H,2H,5H,6H,6aH,7H,8H,9H-imidazo[1,5-f]pteridin-8-yl}phenyl)formamido]pentanedioic acid …
Matched Categories: … Enzymes and Coenzymes …
Kynurenine
Experimental
Matched Synonyms: … (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid ... 3-Anthraniloyl-L-alanine …
Matched Iupac: … (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids …
Matched Iupac: … (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids …
Metenkefalin
Metenkefalin is an endogenous opioid and beta-endorphin. It has been shown to reduce chromosomal abberations in patients with multiple sclerosis. Metenkefalin, along with tridecactide, are under investigation as an immunomodulatory therapy for moderate to severe COVID-19.[L13874,L13877]
Investigational
Matched Synonyms: … Methionine Enkephalin …
Matched Iupac: … 3-(4-hydroxyphenyl)propanamido]acetamido}acetamido)-3-phenylpropanamido]-4-(methylsulfanyl)butanoic acid …
Matched Description: … Metenkefalin is an endogenous opioid and beta-endorphin. …
Matched Salts name: … Metenkefalin acetate …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enkephalin, Methionine …
Matched Iupac: … 3-(4-hydroxyphenyl)propanamido]acetamido}acetamido)-3-phenylpropanamido]-4-(methylsulfanyl)butanoic acid …
Matched Description: … Metenkefalin is an endogenous opioid and beta-endorphin. …
Matched Salts name: … Metenkefalin acetate …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enkephalin, Methionine …
DS-1211
DS-1211 is a potent and selective novel small molecule tissue-nonspecific alkaline phosphatase (TNAP) inhibitor.
Investigational
Matched Synonyms: … N-Acetyl-D-leucine ... N-Acetyl-R-leucine ... D-leucine, N-acetyl- …
Matched Iupac: … (2R)-2-acetamido-4-methylpentanoic acid …
Matched Description: … DS-1211 is a potent and selective novel small molecule tissue-nonspecific alkaline phosphatase (TNAP) …
Matched Iupac: … (2R)-2-acetamido-4-methylpentanoic acid …
Matched Description: … DS-1211 is a potent and selective novel small molecule tissue-nonspecific alkaline phosphatase (TNAP) …
NX-210c
Investigational
Matched Synonyms: … Glycine, L-tryptophyl-L-serylglycyl-L-tryptophyl-L-seryl-L-seryl-L-cysteinyl-L-seryl-L-arginyl-L-seryl-L-cysteinyl ... H-L-tryphophanyl-L-seryl-glycyl-L-tryptophanyl-L-seryl-L-seryl-L-cysteinyl-L-seryl-L-arginyl-L-seryl-L-cysteinyl-glycyl-OH …
Clopidogrel
Clopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and stroke.[A180508,L7213] Clopidogrel is indicated to reduce the risk of myocardial infarction for patients with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and in recent MI, stroke, or established peripheral...
Approved
Matched Iupac: … methyl (2S)-2-(2-chlorophenyl)-2-{4H,5H,6H,7H-thieno[3,2-c]pyridin-5-yl}acetate …
Matched Description: … Clopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and ... with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and ... be superior to [aspirin] in reducing cardiovascular outcomes in patients with cardiovascular disease and …
Matched Mixtures name: … CLOPIDOGREL E ACIDO ACETILSALICILICO VIATRIS ... CLOPIDOGREL E ACIDO ACETILSALICILICO VIATRIS ... Clopidogrel/acetylsalicylic Acid Mylan …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … CLOPIDOGREL ACINO ... CLOPIDOGREL ACINO PHARMA ... Clopidogrel Acino …
Matched Description: … Clopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and ... with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and ... be superior to [aspirin] in reducing cardiovascular outcomes in patients with cardiovascular disease and …
Matched Mixtures name: … CLOPIDOGREL E ACIDO ACETILSALICILICO VIATRIS ... CLOPIDOGREL E ACIDO ACETILSALICILICO VIATRIS ... Clopidogrel/acetylsalicylic Acid Mylan …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … CLOPIDOGREL ACINO ... CLOPIDOGREL ACINO PHARMA ... Clopidogrel Acino …
N(2)-succinyl-L-arginine
Experimental
Matched Synonyms: … Succinyl-arginine ... N2-Succinyl-L-arginine …
Matched Name: … N(2)-succinyl-L-arginine …
Matched Iupac: … (2S)-5-carbamimidamido-2-[(3-carboxy-1-hydroxypropylidene)amino]pentanoic acid …
Matched Name: … N(2)-succinyl-L-arginine …
Matched Iupac: … (2S)-5-carbamimidamido-2-[(3-carboxy-1-hydroxypropylidene)amino]pentanoic acid …
Metyrosine
An inhibitor of the enzyme tyrosine 3-monooxygenase, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with pheochromocytoma. (Martindale, The Extra Pharmacopoeia, 30th ed)
Approved
Matched Synonyms: … α-methyl-p-tyrosine ... (–)-α-methyl-L-tyrosine ... α-methyl-L-p-tyrosine …
Matched Iupac: … (2S)-2-amino-3-(4-hydroxyphenyl)-2-methylpropanoic acid …
Matched Description: … An inhibitor of the enzyme tyrosine 3-monooxygenase, and consequently of the synthesis of catecholamines …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Tyrosine Hydroxylase Inhibitors ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Matched Iupac: … (2S)-2-amino-3-(4-hydroxyphenyl)-2-methylpropanoic acid …
Matched Description: … An inhibitor of the enzyme tyrosine 3-monooxygenase, and consequently of the synthesis of catecholamines …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Tyrosine Hydroxylase Inhibitors ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Denosumab
Denosumab is a novel, fully human IgG2 monoclonal antibody specific to receptor activator of nuclear factor kappa-B ligand (RANKL), suppresses bone resorption via inhibiting RANK-mediated activation of osteoclasts. It is the first and currently the only RANKL inhibitor approved to prevent osteoclast-mediated bone loss. Chemically, it consists of 2 heavy...
Approved
Matched Description: … 215 amino acids and each heavy chain consisting of 448 amino acids with 4 intramolecular disulfides. ... It is the first and currently the only RANKL inhibitor approved to prevent osteoclast-mediated bone loss ... [A263071] Chemically, it consists of 2 heavy and 2 light chains, with each light chain consisting of …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Drugs Affecting Bone Structure and Mineralization …
Matched Products: … Prolia ... PROLIA ... PROLIA® …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Drugs Affecting Bone Structure and Mineralization …
Matched Products: … Prolia ... PROLIA ... PROLIA® …
Phenylalanylamide
Experimental
Matched Synonyms: … Phenylalanine amide ... L-phenylalanine amide …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Methionine Phosphonate
Experimental
Matched Name: … Methionine Phosphonate …
Matched Iupac: … [(1R)-1-amino-3-(methylsulfanyl)propyl]phosphonic acid …
Matched Iupac: … [(1R)-1-amino-3-(methylsulfanyl)propyl]phosphonic acid …
Displaying drugs 626 - 650 of 2924 in total