Displaying drugs 6501 - 6525 of 8039 in total
D-1,4-dithiothreitol
A reagent commonly used in biochemical studies as a protective agent to prevent the oxidation of SH (thiol) groups and for reducing disulphides to dithiols. [PubChem]
Experimental
Matched Description: … A reagent commonly used in biochemical studies as a protective agent to prevent the oxidation of SH ( …
Sphingosine
An amino alcohol with a long unsaturated hydrocarbon chain. Sphingosine and its derivative sphinganine are the major bases of the sphingolipids in mammals. (Dorland, 28th ed)
Experimental
Matched Description: … Sphingosine and its derivative sphinganine are the major bases of the sphingolipids in mammals. …
N-acetyl-alpha-neuraminic acid
An N-acyl derivative of neuraminic acid. N-acetylneuraminic acid occurs in many polysaccharides, glycoproteins, and glycolipids in animals and bacteria. (From Dorland, 28th ed, p1518)
Experimental
Matched Description: … An N-acyl derivative of neuraminic acid. …
N-acetyl-beta-neuraminic acid
An N-acyl derivative of neuraminic acid. N-acetylneuraminic acid occurs in many polysaccharides, glycoproteins, and glycolipids in animals and bacteria. (From Dorland, 28th ed, p1518)
Experimental
Matched Description: … An N-acyl derivative of neuraminic acid. …
Bafetinib
Bafetinib has been used in trials studying the treatment of Adult Gliosarcoma, Adult Mixed Glioma, Adult Glioblastoma, Chronic Myeloid Leukemia, and Acute Lymphocytic Leukemia, among others.
Investigational
Matched Description: … Bafetinib has been used in trials studying the treatment of Adult Gliosarcoma, Adult Mixed Glioma, Adult …
Savolitinib
Savolitinib has been used in trials studying the treatment and health services research of Tumor, Food Effect, Gastric Cancer, Health Subjects, and Colorectal Cancer, among others.
Investigational
Matched Description: … Savolitinib has been used in trials studying the treatment and health services research of Tumor, Food …
Denenicokin
Denenicokin is under investigation in clinical trial NCT01152788 (Phase II Study of Interleukin-21 (rIL-21) vs Dacarbazine (DTIC) in Patients With Metastatic or Recurrent Melanoma).
Investigational
Matched Description: … Denenicokin is under investigation in clinical trial NCT01152788 (Phase II Study of Interleukin-21 (rIL …
Lobaplatin
Lobaplatin has been used in trials studying the treatment of Breast Cancer, Hepatocellular Carcinoma, and Lobaplatin and Gemcitabine in Combination, Second-line Treatments on Advanced Osteosarcoma.
Investigational
Matched Description: … Lobaplatin has been used in trials studying the treatment of Breast Cancer, Hepatocellular Carcinoma, …
Poly(lactic acid)
Poly(lactic acid) is under investigation in clinical trial NCT00126308 (Facial Lipoatrophy Trial: Immediate Versus Deferred Injections of Poly-L-Lactic Acid for HIV Facial Lipoatrophy).
Investigational
Matched Description: … investigation in clinical trial NCT00126308 (Facial Lipoatrophy Trial: Immediate Versus Deferred Injections of …
Istiratumab
Istiratumab is under investigation in clinical trial NCT02399137 (A Phase 2 Study of MM-141 Plus Nab-paclitaxel and Gemcitabine in Front-line Metastatic Pancreatic Cancer).
Investigational
Matched Description: … Istiratumab is under investigation in clinical trial NCT02399137 (A Phase 2 Study of MM-141 Plus Nab-paclitaxel …
Cerdulatinib
Cerdulatinib is under investigation in clinical trial NCT04021082 (CELTIC-1: A Phase 2B Study of Cerdulatinib in Patients With Relapsed/refractory Peripheral T-cell Lymphoma (PTCL)).
Investigational
Matched Description: … Cerdulatinib is under investigation in clinical trial NCT04021082 (CELTIC-1: A Phase 2B Study of Cerdulatinib …
NCX-1000
NCX-1000 is under investigation in clinical trial NCT00414869 (Preliminary Efficacy and Tolerability of NCX-1000 After Repeated Oral Doses in Patients With Elevated Portal Pressure).
Investigational
Matched Description: … NCX-1000 is under investigation in clinical trial NCT00414869 (Preliminary Efficacy and Tolerability of …
Indatuximab ravtansine
Indatuximab ravtansine is under investigation in clinical trial NCT01001442 (Safety and Dose Determining Multi-dose Study of BT062 in Patients With Relapsed or Refractory Multiple Myeloma).
Investigational
Matched Description: … is under investigation in clinical trial NCT01001442 (Safety and Dose Determining Multi-dose Study of …
Pegylated Recombinant Human Arginase I
Pegylated Recombinant Human Arginase I is under investigation in clinical trial NCT03455140 (A Study Evaluating the Safety and Activity of Pegylated Recombinant Human Arginase (BCT-100)).
Investigational
Matched Description: … I is under investigation in clinical trial NCT03455140 (A Study Evaluating the Safety and Activity of …
Quavonlimab
Quavonlimab is under investigation in clinical trial NCT03179436 (Study of Quavonlimab (MK-1308) in Combination With Pembrolizumab (MK-3475) in Advanced Solid Tumors (MK-1308-001)).
Investigational
Matched Description: … Quavonlimab is under investigation in clinical trial NCT03179436 (Study of Quavonlimab (MK-1308) in Combination …
SAR421869
SAR421869 is a Lentiviral Vector Containing The Human My07A Gene currently being investigated for the treatment of retinitis pigmentosa associated with Usher syndrome 1B gene defect.
Investigational
Matched Description: … a Lentiviral Vector Containing The Human My07A Gene currently being investigated for the treatment of …
Briakinumab
Briakinumab is a human anti-IL-12 monoclonal antibody being developed for the treatment of a number of T-cell driven autoimmune diseases. It targets and neutralize interleukin-12 and interleukin-23, two proteins associated with inflammation, such as pro-inflammatory interleukins or tumor necrosis factor- alpha. Briakinumab represents a novel approach to treating psoriasis, Multiple...
Investigational
Matched Description: … Briakinumab is a human anti-IL-12 monoclonal antibody being developed for the treatment of a number of ... As of 2011 drug development for psoriasis has been discontinued in the U.S. and Europe. …
humanized SMART Anti-IL-12 Antibody
The humanized anti-IL-12 antibody is an important addition to PDL's already strong pipeline of humanized antibodies being developed for the treatment of autoimmune diseases. SMART Anti-IL-12 Antibody was humanized at PDL from a murine anti-IL-12 antibody that was licensed, together with certain intellectual property related to anti-IL-12 therapy, from Hoffmann-La...
Investigational
Matched Description: … antibodies being developed for the treatment of autoimmune diseases. ... The humanized anti-IL-12 antibody is an important addition to PDL's already strong pipeline of humanized ... IL-12 is a cytokine that may have considerable potential as a target in the therapy of autoimmune diseases …
R-30490
R-30490 is an opioid related to carfentanil used as an animal tranquilizer. It was first synthesized by Janssen Pharmaceutica as part of a structure-activity relationship study of fentanly and its derivatives. R-30490 was found to be the most selective agonist for the mu opioid receptor out of all the fentanyl...
Experimental
Matched Description: … of fentanly and its derivatives. ... It was first synthesized by Janssen Pharmaceutica as part of a structure-activity relationship study ... R-30490 was found to be the most selective agonist for the mu opioid receptor out of all the fentanyl …
Bleomycin A6
Bleomycin A6 (also known as boanmycin) has been used in trials studying the treatment of Squamous Cell Lung Cancer. It was developed in China as an antineoplastic antibiotic. This drug participated in clinical trials for the treatment of Squamous Cell Lung Cancer. It was shown that besides the antitumor effect,...
Investigational
Matched Description: … The development of this drug, apparently, was discontinued. ... This drug participated in clinical trials for the treatment of Squamous Cell Lung Cancer. ... Bleomycin A6 (also known as boanmycin) has been used in trials studying the treatment of Squamous Cell …
Heptabarbital
Heptabarbital is an intermediate or short term barbiturate used mainly for sedation and hypnosis.
Experimental
Bimagrumab
Bimagrumab has been used in trials studying the treatment and supportive care of Sarcopenia, Skeletal Muscle, Mechanical Ventilation, Sporadic Inclusion Body Myositis, and Sporadic Inclusion Body Myositis (sIBM), among others.
Investigational
Matched Description: … Bimagrumab has been used in trials studying the treatment and supportive care of Sarcopenia, Skeletal …
Nerve Growth Factor
Nerve Growth Factor has been used in trials studying the prevention and treatment of Mental Handicap, Alzheimer's Disease, Traumatic Brain Injury, Cerebral Palsy Children, and Delayed Speech Development, among others.
Investigational
Matched Description: … Nerve Growth Factor has been used in trials studying the prevention and treatment of Mental Handicap, …
Emrusolmin
Emrusolmin restores hippocampal synaptic and transcriptional plasticity as well as spatial memory in a mouse model for Alzheimer's disease, when given orally before or after the onset of pathology.
Experimental
Matched Description: … spatial memory in a mouse model for Alzheimer's disease, when given orally before or after the onset of …
Rovafovir etalafenamide
Rovafovir etalafenamide is under investigation in clinical trial NCT03472326 (Efficacy of GS-9131 Functional Monotherapy in HIV-1-Infected Adults Failing a Nucleos(t)Ide Reverse Transcriptase Inhibitor-Containing Regimen).
Investigational
Matched Description: … Rovafovir etalafenamide is under investigation in clinical trial NCT03472326 (Efficacy of GS-9131 Functional …
Displaying drugs 6501 - 6525 of 8039 in total