Displaying drugs 6626 - 6650 of 8282 in total
PEG-uricase
PEG-uricase, a polyethylene glycol ("PEG") conjugate of recombinant porcine uricase (urate oxidase), which breaks down the uric acid deposits is being studied in Phase III clinical trials for the treatment of severe, treatment-refractory gout in the United States in 2006.
Investigational
Matched Description: … PEG-uricase, a polyethylene glycol ("PEG") conjugate of recombinant porcine uricase (urate oxidase), ... breaks down the uric acid deposits is being studied in Phase III clinical trials for the treatment of …
(4R)-limonene
Limonene is common in cosmetic products. As the main odor constituent of citrus (plant family Rutaceae), D-limonene is used in food manufacturing and some medicines, e.g. as a flavoring to mask the bitter taste of alkaloids, and as a fragrant in perfumery.
Investigational
Matched Description: … As the main odor constituent of citrus (plant family Rutaceae), D-limonene is used in food manufacturing ... and some medicines, e.g. as a flavoring to mask the bitter taste of alkaloids, and as a fragrant in …
Rimiducid
Rimiducid is a lipid-permeable tacrolimus analogue and a protein dimerizer. It was designed to overcome limitations of current cellular immunotherapies used for cancer and other blood disorders by enhancing the control of the immune cell activity and function. When administered via chemically-inducible dimerization (CID) technologies, rimiducid binds to switch proteins...
Investigational
Matched Description: … blood disorders by enhancing the control of the immune cell activity and function. ... It was designed to overcome limitations of current cellular immunotherapies used for cancer and other ... [A187496,L9521] The combination use of rimiducid with immunotherapies for enhanced therapeutic effectiveness …
Tyramine
Tyramine (4-hydroxyphenethylamine; para-tyramine, mydrial or uteramin) is a naturally occurring monoamine compound and trace amine derived from the amino acid tyrosine. Tyramine acts by inducing the release of catecholamine. An important characteristic of this product is its impediment to cross the blood-brain barrier which restrains its side effects to only...
Investigational
Nutraceutical
Matched Description: … Tyramine acts by inducing the release of catecholamine. ... An important characteristic of this product is its impediment to cross the blood-brain barrier which ... There have been reports of hypertensive crisis in patients ingesting tyramine-rich diet in conjunction …
Paquinimod
Paquinimod is developed for the treatment of SLE (Systemic Lupus Erythematosus), which is an autoimmune disease. The disease affects mainly women of fertile age and progresses in flares with relatively symptom free periods in between. Current treatments of SLE are NSAID (nonsteroidal anti-inflammatory drugs), corticosteroids, antimalarians or cytotoxic drugs like...
Investigational
Matched Description: … Paquinimod is developed for the treatment of SLE (Systemic Lupus Erythematosus), which is an autoimmune ... The disease affects mainly women of fertile age and progresses in flares with relatively symptom free ... Current treatments of SLE are NSAID (nonsteroidal anti-inflammatory drugs), corticosteroids, antimalarians …
Human Umbilical Cord Mesenchymal Stem Cells
Stem cells obtained from amniotic fluid, the umbilical cord (UC), and placenta are gaining in popularity. Stem cells from the umbilical cord offer several advantages, including: non-invasive collection procedures, more hearty and steady growth than bone-marrow derived stem cells (they can maintain a steady doubling time (DT) over up to...
Investigational
Matched Description: … of extracted MSCs. ... The cord lining of the UC is generally isolated with the explant method -- resulting in two kinds of ... Currently many companies are creating their own version of these stem cells, one of which is by Aspire …
Picolinic acid
PCL-016 or Picolinic acid drug substance is a pyridine carboxylate metabolite of tryptophan. It acts as an anti-infective and immunomodulator and is produced in approximately 25-50 mg quantities by the body on a daily basis through the breakdown of tryptophan. PCL-016 plays a key role in zinc transport. As a...
Investigational
Matched Description: … PCL-016 or Picolinic acid drug substance is a pyridine carboxylate metabolite of tryptophan. ... is produced in approximately 25-50 mg quantities by the body on a daily basis through the breakdown of ... Acne vulgaris, herpes and other viral infections therefore pose potential therapeutic targets of PCL- …
Pyrroloquinoline Quinone
A pyrrolo-quinoline having two adjacent keto-groups at the 4 and 5 positions and three acidic carboxyl groups. It is a coenzyme of some DEHYDROGENASES. [PubChem]
Experimental
Matched Description: … It is a coenzyme of some DEHYDROGENASES. [PubChem] …
Adenosine 5'-phosphosulfate
5'-Adenylic acid, monoanhydride with sulfuric acid. The initial compound formed by the action of ATP sulfurylase on sulfate ions after sulfate uptake. Synonyms: adenosine sulfatophosphate; APS.
Experimental
Investigational
Matched Description: … The initial compound formed by the action of ATP sulfurylase on sulfate ions after sulfate uptake. …
Allosamidin
Allosamidin exhibits extremely potent inhibitory activity against chitinases from a number of sources, particularly from Candida albicans, and can be utilized as potent antifungal agent.
Experimental
Matched Description: … Allosamidin exhibits extremely potent inhibitory activity against chitinases from a number of sources …
NGX267
NGX267 is a muscarinic agonist. It is developed for the treatment of Alzheimer’s disease and has shown the potential to both reduce symptoms and slow disease progression.
Investigational
Matched Description: … It is developed for the treatment of Alzheimer’s disease and has shown the potential to both reduce symptoms …
AZD 3355
AZD 3355 is a reflux inhibitor used for the treatment of Gastroesophageal Reflux Disease. It is developed by AstraZeneca and is currently in phase I/II trials.
Investigational
Matched Description: … AZD 3355 is a reflux inhibitor used for the treatment of Gastroesophageal Reflux Disease. …
Rabeximod
Rabeximod is an orally administered compound for treatment of moderate or severe active rheumatoid arthritis that is currently undergoing phase II clinical testing in eight European countries.
Investigational
Matched Description: … Rabeximod is an orally administered compound for treatment of moderate or severe active rheumatoid arthritis …
AVI-4020
AVI-4020 is a neugene antisense drug candidate for the treatment of patients with acute West Nile virus disease who have serious neurological impairment (WNV neuroinvasive disease).
Investigational
Matched Description: … AVI-4020 is a neugene antisense drug candidate for the treatment of patients with acute West Nile virus …
PF-06282999
Pf 06282999 is under investigation in clinical trial NCT01626976 (A Study To Assess The Safety, Tolerability And Pharmacokinetics Of PF-06282999 Administered Orally In Healthy Adult Subjects).
Investigational
Matched Description: … investigation in clinical trial NCT01626976 (A Study To Assess The Safety, Tolerability And Pharmacokinetics Of …
Oprozomib
Oprozomib has been used in trials studying the treatment of Solid Tumors, Multiple Myeloma, Waldenstrom Macroglobulinemia, Advanced Hepatocellular Carcinoma, and Advanced Non-Central Nervous System (CNS) Malignancies.
Investigational
Matched Description: … Oprozomib has been used in trials studying the treatment of Solid Tumors, Multiple Myeloma, Waldenstrom …
Nimorazole
Nimorazole has been used in trials studying the treatment of Hypoxia, Radiotherapy, Hypoxic Modification, Gene Profile, Gene Signature, and Head and Neck Squamous Cell Carcinoma, among others.
Investigational
Matched Description: … Nimorazole has been used in trials studying the treatment of Hypoxia, Radiotherapy, Hypoxic Modification …
Etaracizumab
Etaracizumab has been investigated for the treatment of Psoriasis, Renal Cell Carcinoma, Stage IV Renal Cell Cancer, Recurrent Renal Cell Cancer, and Stage III Renal Cell Cancer.
Investigational
Matched Description: … Etaracizumab has been investigated for the treatment of Psoriasis, Renal Cell Carcinoma, Stage IV Renal …
Bavisant
Bavisant has been used in trials studying the basic science and treatment of Alcoholism, Pharmacokinetics, Drug Interactions, Attention Deficit Hyperactivity Disorder, and Attention Deficit Disorders With Hyperactivity.
Investigational
Matched Description: … Bavisant has been used in trials studying the basic science and treatment of Alcoholism, Pharmacokinetics …
GSK-356278
Gsk356278 has been used in trials studying the treatment and basic science of Anxiety Disorders, Huntington Disease, Depressive Disorder, Huntingtons Disease, and Depressive Disorder, Major, among others.
Investigational
Matched Description: … Gsk356278 has been used in trials studying the treatment and basic science of Anxiety Disorders, Huntington …
JNJ-42396302
Jnj 42396302 is under investigation in clinical trial NCT01732237 (A Study to Investigate the Pharmacokinetics of JNJ-42396302, JNJ-53773187 and JNJ-42692507 in Healthy Male Participants).
Investigational
Matched Description: … 42396302 is under investigation in clinical trial NCT01732237 (A Study to Investigate the Pharmacokinetics of …
Reposal
Reposal is a barbiturate derivative invented in the 1960s in Denmark that has sedative, hypnotic and anticonvulsant properties. It was used primarily in the treatment of insomnia.
Experimental
Matched Description: … It was used primarily in the treatment of insomnia. …
AZD-4017
AZD-4017 is under investigation in clinical trial NCT01173471 (A Phase IIa Study to Assess the Tolerability, Safety, and Efficacy of AZD4017 for Raised Intra-ocular Pressure).
Investigational
Matched Description: … investigation in clinical trial NCT01173471 (A Phase IIa Study to Assess the Tolerability, Safety, and Efficacy of …
Difamilast
Difamilast is under investigation in clinical trial NCT01702181 (A Safety Study to Evaluate the Use and Effectiveness of a Topical Ointment to Treat Adults With Atopic Dermatitis).
Investigational
Matched Description: … under investigation in clinical trial NCT01702181 (A Safety Study to Evaluate the Use and Effectiveness of …
LSZ-102
LSZ-102 is under investigation in clinical trial NCT02734615 (Phase I/Ib Trial of LSZ102 Single Agent or LSZ102 + LEE011 or LSZ102 + BYL719 in ER+ Breast Cancers).
Investigational
Matched Description: … LSZ-102 is under investigation in clinical trial NCT02734615 (Phase I/Ib Trial of LSZ102 Single Agent …
Displaying drugs 6626 - 6650 of 8282 in total