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Displaying drugs 651 - 675 of 1018 in total
Endostar is under investigation for the treatment of Nasopharyngeal Carcinoma. Endostar has been investigated for the treatment of Non-small Cell Lung Cancer.
Investigational
Matched Synonyms: … Recombinant human endostatin protein ... N-TERMINAL-MGGSHHHHH-ENDOSTATIN (HUMAN RECOMBINANT) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Ofatumumab is a novel anti-CD20 monoclonal antibody that targets B-cells. It is an IgG1κ human monoclonal antibody produced from a recombinant murine cell line (NS0) via transgenic mouse and hybridoma technology. Ofatumumab works by recognizing antigens that are expressed on the tumour cells in certain cancers; however, the antigen is...
Approved
Matched Synonyms: … HuMax-CD20 ... HuMax-CD20, 2F2 …
Matched Description: … It is an IgG1κ human monoclonal antibody produced from a recombinant murine cell line (NS0) via transgenic ... mouse and hybridoma technology. ... In February 2020, FDA and EMA approved Supplemental Biologics License Application (sBLA) and Marketing …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Finotonlimab is under investigation in clinical trial NCT04560894 (SCT-I10A Plus SCT510 Versus Sorafenib as First-line Therapy for Advanced Hepatocellular Carcinoma).
Investigational
Matched Synonyms: … Immunoglobulin g4 (226-proline), anti-(human programmed cell death 1) (human-mus musculus monoclonal ... sct-i10a .gamma.4-chain), disulfide with human-mus musculus monoclonal sct-i10a .kappa. …
Clesrovimab is under investigation in clinical trial NCT04938830 (Clesrovimab (MK-1654) in Infants and Children at Increased Risk for Severe Respiratory Syncytial Virus (RSV) Disease (MK-1654-007)).
Investigational
Matched Synonyms: … f protein) (human monoclonal rb1 .gamma.1-chain), disulfide with human monoclonal rb1 .kappa. ... Immunoglobulin g1 (262-tyrosine,264-threonine,266-glutamic acid), anti-(human respiratory syncytial virus …
Matched Description: … Clesrovimab is under investigation in clinical trial NCT04938830 (Clesrovimab (MK-1654) in Infants and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Teropavimab is under investigation in clinical trial NCT05729568 (A Study of GS-5423 and GS-2872 in Combination With Capsid Inhibitor Lenacapavir in Virologically Suppressed Adults With HIV-1 Infection).
Investigational
Matched Synonyms: … ) (human monoclonal 8c11-62a12 .gamma.1-chain), disulfide with human monoclonal 8c11-62a12 .kappa. ... Immunoglobulin g1 (434-leucine,440-serine), anti-(human immunodeficiency virus 1 envelope protein gp120env …
Matched Description: … Teropavimab is under investigation in clinical trial NCT05729568 (A Study of GS-5423 and GS-2872 in Combination …
Obinepitide is a synthetic analogue of two natural human hormones, PYY and Pancreatic Polypeptide, which normally are released during a meal. These hormones are known to play a role in the regulation of food intake and appetite in man as satiety signal from the GI-tract to the CNS. In obinepitide,...
Investigational
Matched Synonyms: … (34-L-glutamine)pancreatic hormone (human) …
Matched Description: … Obinepitide is a synthetic analogue of two natural human hormones, PYY and Pancreatic Polypeptide, which ... These hormones are known to play a role in the regulation of food intake and appetite in man as satiety …
Investigational
Matched Synonyms: … Proteinase inhibitor m/nei (synthetic human) ... Recombinant human neutrophil inhibitor (hne) ... Human recombinant neutrophil elastase inhibitor, homologue of the second kunitz domain of inter-alpha-trypsin …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Talditercept alfa is under investigation in clinical trial NCT03039686 (Clinical Trial to Evaluate the Efficacy, Safety, and Tolerability of RO7239361 in Ambulatory Boys With Duchenne Muscular Dystrophy).
Investigational
Matched Synonyms: … protein with adnectin, anti-(human growth differentiation factor 8) (human clone bms-986089 fibronectin ... Bivalent Anti-Human Myostatin Adnectin-Igg1 ... Bms-986089 (fully human anti-myostatin adnectin) …
Matched Description: … under investigation in clinical trial NCT03039686 (Clinical Trial to Evaluate the Efficacy, Safety, and
STX-100 is under investigation in clinical trial NCT01371305 (STX-100 in Patients With Idiopathic Pulmonary Fibrosis (IPF)).
Investigational
Matched Synonyms: … Humanized monoclonal antibody against human integrin alphaVbeta6 …
Investigational
Matched Synonyms: … TCN-202 (human anti-cytomegalovirus monoclonal antibody) …
Investigational
Matched Synonyms: … Deoxyribonuclease (synthetic human), amide with 1,2-ethanediamine …
CER-001 is a negatively charged lipoprotein particle comprising human recombinant apolipoprotein A-I and two phospholipids: sphingomyelin and dipalmitoylphosphatidylglycerol. It is under investigation for the treatment of lecithin-cholesterol acyltransferase (LCAT) deficiencies.
Investigational
Matched Synonyms: … Recombinant human apolipoprotein A-I/phospholipid complexes …
Matched Description: … and two phospholipids: sphingomyelin and dipalmitoylphosphatidylglycerol. ... CER-001 is a negatively charged lipoprotein particle comprising human recombinant apolipoprotein A-I …
Matched Categories: … Amino Acids, Peptides, and Proteins …
HH-009 is a recombinant human IgG4 monoclonal antibody against FGF19 being studied for the treatment of hepatocellular carcinoma.
Investigational
Matched Synonyms: … recombinant human IgG4 monoclonal antibody against FGF19 …
Matched Description: … HH-009 is a recombinant human IgG4 monoclonal antibody against FGF19 being studied for the treatment …
Investigational
Matched Synonyms: … Immunoglobulin g4 (228-proline), anti-(human programmed cell death protein 1) (human monoclonal bi754091 ... .gamma.4-chain), disulfide with human monoclonal bi754091 .kappa. …
Investigational
Matched Synonyms: … Immunoglobulin g4(231-proline), anti-(human programmed cell death protein 1) (human monoclonal ab122 ... .gamma.4-chain), disulfide with human monoclonal ab122 .lambda. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Avizakimab is under investigation in clinical trial NCT03371251 (Study of BOS161721 in Systemic Lupus Erythematosus (SLE) Patients on a Background of Limited Standard of Care).
Investigational
Matched Synonyms: … Immunoglobulin g1 (251-tyrosine,253-threonine,255-glutamic acid), anti-(human interleukin 21) (human-mus ... musculus monoclonal bos161721 .gamma.1-chain), disulfide with human-mus musculus monoclonal bos161721 …
Approved
Investigational
Matched Name: … Zoledronate D,L-Lysine Monohydrate …
Dimehydrinate was first described in the literature in 1949, and patented in 1950. Early research into dimenhydrinate focused on its role as an antihistamine for urticaria; the treatment of motion sickness was an accidental discovery. Dimenhydrinate, also known as B-dimethylaminoethyl benzohydrol ether 8-chlorotheophyllinate, is indicated to prevent nausea, vomiting, and...
Approved
Matched Description: … Dimehydrinate was first described in the literature in 1949,[A233120] and patented in 1950. ... ] in a salt form, with 53%-55.5% dried diphenhydramine, and 44%-47% died 8-chlorotheophylline. ... [L32980,L32985,L32995] Dimenhydrinate is a combination of [Diphenhydramine] and [8-chlorotheophylline …
Matched Products: … Dramamine Original Formula ... Dramamine Chewable Formula ... Motion Sickness Original Formula
Elosulfase alfa is a synthetic version of the enzyme N-acetylgalactosamine-6-sulfatase. It was approved by the FDA in 2014 for the treatment of Morquio syndrome. Elosulfase alfa was developed by BioMarin Pharmaceutical Inc. and is marketed under the brand Vimizim™. The recommended dose is 2 mg per kg given intravenously over...
Approved
Investigational
Matched Synonyms: … Recombinant human N-acetylgalactosamine-6-sulfatase ... Recombinant human N-acetylgalactosamine-6-sulfatase (rhGALNS) …
Matched Description: … Elosulfase alfa was developed by BioMarin Pharmaceutical Inc. and is marketed under the brand Vimizim …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism ... Chondroitinases and Chondroitin Lyases …
Stem cells are self-renewing and proliferate without differentiation, with the two major groups being embryonic stem cells (ESCs) and adult stem cells (ASC). Differentiation occurs under different conditions into different cell types. ESCs are from the inner cell mass of blastocysts while ASCs are deposited into adult tissues with restricted...
Investigational
Matched Name: … Human Menstrual Blood-derived Stem Cells …
Matched Description: … embryonic stem cells (ESCs) and adult stem cells (ASC). ... Stem cells are self-renewing and proliferate without differentiation, with the two major groups being ... These cells possess a high rate of proliferation and multi-lineage differentiation potency. …
Investigational
Matched Synonyms: … RECOMBINANT HUMAN BONE MORPHOGENETIC PROTEIN 4 …
Matched Name: … Human Recombinant Bone Morphogenetic Protein 4 …
Investigational
Matched Name: … Human Embryonic Stem Cell-derived Astrocytes …
Investigational
Matched Name: … Recombinant human palmitoyl protein thioesterase-1 …
Lutropin alfa is a recombinant human luteinizing hormone produced in yeast with 2 subunits, alpha = 92 residues, beta = 121 residues. It is a heterodimeric glycoprotein made up of monomeric units. Lutropin alfa was the first and only recombinant human form of luteinizing hormone (LH) developed for use in...
Approved
Matched Description: … Lutropin alfa was the first and only recombinant human form of luteinizing hormone (LH) developed for ... biological activity of endogenous LH; an acute rise of LH, or LH surge, in females triggers ovulation and ... Lutropin alfa is a recombinant human luteinizing hormone produced in yeast with 2 subunits, alpha = 92 …
Matched Mixtures name: … Pergoveris 150IU/75IU powder and solvent for solution for injection ... Pergoveris Powder and Solvent for Solution for Injection 150iu/75iu …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gonadotropins and Antigonadotropins ... Sex Hormones and Modulators of the Genital System …
Matched Products: … LUVERIS FOR INJECTION 75 iu/vial (Revised formula) …
Investigational
Matched Synonyms: … TNFSF14) (human-Mus musculus monoclonal SAR252067 γ4-chain), disulfide with human-Mus musculus monoclonal ... Immunoglobulin G4 [230-proline,237-glutamic acid], anti-(human tumor necrosis factor superfamily protein …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Displaying drugs 651 - 675 of 1018 in total