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Displaying drugs 651 - 675 of 2060 in total
Experimental
Investigational
Matched Synonyms: … D-methyl aspartic acid ... 3-methyl-beta-D-aspartic acid …
Matched Name: … (3S)-3-methyl-D-aspartic acid …
Riociguat is a soluble guanylate cyclase (sGC) agonist approved in the USA, Europe and several other regions for patients with group I PAH (pulmonary arterial hypertension) in WHO FC II or III; and for the treatment of patients with inoperable CTEPH (chronic thromboembolic pulmonary hypertension), or persistent/recurrent PH (pulmonary hypertension)...
Approved
Matched Synonyms: … Methyl N-[4,6-Diamino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl]-N-methyl-carbaminate …
Matched Iupac: … methyl N-(4,6-diamino-2-{1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl}pyrimidin-5-yl)-N-methylcarbamate …
Matched Description: … Riociguat is a soluble guanylate cyclase (sGC) agonist approved in the USA, Europe and several other ... regions for patients with group I PAH (pulmonary arterial hypertension) in WHO FC II or III; and for …
Experimental
Matched Synonyms: … Ecgonine methyl ester …
Matched Iupac: … methyl (1R,2R,3S,5S)-3-hydroxy-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate …
Lazuvapagon is under investigation in clinical trial NCT03116191 (Trial of SK-1404 for Nocturia Due to Nocturnal Polyuria in Japanese Subjects).
Investigational
Matched Synonyms: … (4s)-n-((2s)-1-hydroxypropan-2-yl)-methyl-1-(2-methyl-4-(3-methyl-1h-pyrazol-1-yl)benzoyl)-2,3,4,5-tetrahydro ... 1h-1-benzazepine-4-carboxamide, 2,3,4,5-tetrahydro-n-((1s)-2-hydroxy-1-methylethyl)-4-methyl-1-(2-methyl ... -4-(3-methyl-1h-pyrazol-1-yl)benzoyl)-, (4s)- …
Alosetron is a 5-HT3 antagonist used only for the management of severe diarrhoea-predominant irritable bowel syndrome (IBS) in women. Alosetron has an antagonist action on the 5-HT3 receptors and thus may modulate serotonin-sensitive gastrointestinal (GI) processes. Alosetron was voluntarily withdrawn from the US market in November 2000 by the manufacturer...
Approved
Withdrawn
Matched Synonyms: … 2,3,4,5-Tetrahydro-5-methyl-2-((5-methyl-1H-imidazol-4-yl)methyl)-1H-pyrido(4,3-b)indol-1-one …
Matched Iupac: … 5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-1H,2H,3H,4H,5H-pyrido[4,3-b]indol-1-one …
Matched Description: … reports of severe adverse effects including ischemic colitis, severely obstructed or ruptured bowel, and ... Alosetron has an antagonist action on the 5-HT3 receptors and thus may modulate serotonin-sensitive gastrointestinal …
Matched Categories: … Alimentary Tract and Metabolism …
Experimental
Matched Synonyms: … (alphaS)-alpha-(((5-(3-Methyl-1H-indazol-5-yl)-3-pyridinyl)oxy)methyl)benzeneethanamine …
Matched Iupac: … (2S)-1-{[5-(3-methyl-1H-indazol-5-yl)pyridin-3-yl]oxy}-3-phenylpropan-2-amine …
Mangostin is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … 7-o-methyl-.gamma.-mangostin ... 7-o-methyl-4-desprenylcostatin …
Experimental
Matched Synonyms: … 1-amino-2-methyl-4-naphthol ... 3-methyl-4-amino-1-naphthol ... 4-amino-3-methyl-1-naphthol …
Experimental
Matched Name: … Methyl alpha-galactoside …
Experimental
Matched Name: … S-Methyl Phosphocysteine …
Experimental
Matched Synonyms: … Glutathione S-methyl ester ... L-gamma-Glutamyl-S-methyl-L-cysteinylglycine …
Matched Name: … S-Methyl glutathione …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Methyl-D9-choline is under investigation in clinical trial NCT01807910 (ER Stress in NAFLD).
Investigational
Matched Name: … Methyl-D9-choline …
Matched Description: … Methyl-D9-choline is under investigation in clinical trial NCT01807910 (ER Stress in NAFLD). …
SB-224289 is a small molecule with a high affinity for human 5-HT1B receptors.
Investigational
Matched Synonyms: … (1'-methyl-6,7-dihydro-5h-spiro(furo(2,3-f)indole-3,4'-piperidin)-5-yl)(2'-methyl-4'-(5-methyl-1,2,4- ... (2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-(1,1'-biphenyl)-4-yl)(1'-methyl-6,7-dihydrospiro(furo(2,3 ... 6,7-dihydro-1'-methyl-5-((2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-1,1'-biphenyl-4-yl)carbonyl)spiro …
Matched Iupac: … 1'-methyl-5-[2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-carbonyl]-2,5,6,7-tetrahydrospiro …
An anticonvulsant especially useful in the treatment of absence seizures unaccompanied by other types of seizures.
Approved
Matched Synonyms: … 2-methyl-2-ethylsuccinimide ... 3-methyl-3-ethylsuccinimide ... α-methyl-α-ethylsuccinimide …
Investigational
Matched Synonyms: … Hexanoic acid, 3-methyl-6-(2-((5-methyl-2-(4-(trifluoromethyl)phenyl)-1h-imidazol-1-yl)methyl)phenoxy …
Matched Iupac: … (3R)-3-methyl-6-[2-({5-methyl-2-[4-(trifluoromethyl)phenyl]-1H-imidazol-1-yl}methyl)phenoxy]hexanoic …
Investigational
Matched Synonyms: … -(methyl-11c)- ... -methyl-l-tryptophan C-11 …
Investigational
Matched Synonyms: … )amino)methyl) phenyl ester ... 1-piperidinecarboxylic acid, 2-((methylamino)methyl)-, 2-methoxy-4-((((6e)-8-methyl-1-oxo-6-nonen-1-yl ... 2-methoxy-4-(((6e)-8-methylnon-6-enamido)methyl)phenyl (2rs)-2-((methylamino)methyl)piperidine-1-carboxylate …
Matched Iupac: … 2-methoxy-4-{[(6E)-8-methylnon-6-enamido]methyl}phenyl 2-[(methylamino)methyl]piperidine-1-carboxylate …
Dexlansoprazole is a new-generation proton pump inhibitor (PPI) used for the management of symptoms associated with gastroesophageal reflux disease (GERD) and erosive esophagitis. Dexlansoprazole is the R-enantiomer of DB00448, which is composed of a racemic mixture of the R- and S-enantiomers. Compared to the older generation of PPIs (which includes...
Approved
Investigational
Matched Synonyms: … (+)-2-((R)-((3-METHYL-4-(2,2,2-TRIFLUOROETHOXY)PYRIDIN-2-YL)METHYL)SULFINYL)-1H-BENZIMIDAZOLE ... 1H-BENZIMIDAZOLE, 2-((R)-((3-METHYL-4-(2,2,2-TRIFLUOROETHOXY)-2-PYRIDINYL)METHYL)SULFINYL)- ... 2-((R)-((3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl)methyl)sulfinyl)-1H-benzimidazole …
Matched Iupac: … 2-[(R)-[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methanesulfinyl]-1H-1,3-benzodiazole …
Matched Description: … inhibitor (PPI) used for the management of symptoms associated with gastroesophageal reflux disease (GERD) and ... Dexlansoprazole is the R-enantiomer of [DB00448], which is composed of a racemic mixture of the R- and ... Compared to the older generation of PPIs (which includes [DB00213], [DB00338], and [DB00448]),[A178084 …
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
A muscarinic antagonist used to study binding characteristics of muscarinic cholinergic receptors.
Approved
Matched Synonyms: … Hyoscine methyl bromide ... (−)-scopolamine methyl bromide ... Scopolamine methyl bromide …
3-Methyl-thiofentanyl is a fentanyl analog and an opioid analgesic that works by inducing central nervous system (CNS) depression.
Experimental
Illicit
Matched Synonyms: … 3-Methyl-thiofentanyl …
Matched Iupac: … N-{3-methyl-1-[2-(thiophen-2-yl)ethyl]piperidin-4-yl}-N-phenylpropanamide …
Matched Description: … 3-Methyl-thiofentanyl is a [fentanyl] analog and an opioid analgesic that works by inducing central nervous …
Experimental
Matched Synonyms: … 2-methyl-4-butanol ... 3-methyl-1-butanol …
Oxilofrine is used in combination with DB11609 as an antitussive. It is currently marketed in Canada by Valeant under the tradename Cophylac.
Approved
Matched Synonyms: … Methyl synephrin ... Methyl synephrine …
Experimental
Matched Synonyms: … 3-Methyl-D-glucose ... O(3)-methyl-D-glucose …
Matched Name: … 3-O-Methyl-d-glucose …
Investigational
Matched Synonyms: … 2-chloro-6-methyl-n'-(4-methyl-3-(2-(quinolin-3-yl)ethynyl)benzoyl)benzohydrazide ... Benzoic acid, 2-chloro-6-methyl-, 2-(4-methyl-3-(2-(3-quinolinyl)ethynyl)benzoyl)hydrazide ... 4-methyl-3-quinolin-3-yl-ethynyl benzoic acid n'-(2-chloro-6-methylbenzoyl)hydrazide …
Matched Iupac: … 2-chloro-6-methyl-N'-{4-methyl-3-[2-(quinolin-3-yl)ethynyl]benzoyl}benzohydrazide …
Investigational
Matched Synonyms: … 2-(isopropylamino)-3-methyl-5-(6-methyl-5-((2-(1-methyl-1h-pyrazol-4-yl)pyridin-4-yl)oxy)pyridin-2-yl ... 4(3h)-pyrimidinone, 3-methyl-2-((1-methylethyl)amino)-5-(6-methyl-5-((2-(1-methyl-1h-pyrazol-4-yl)-4- ... 3-methyl-2-((1-methylethyl)amino)-5-(6-methyl-5-((2-(1-methyl-1h-pyrazol-4-yl)-4-pyridinyl)oxy)-2-pyridinyl …
Matched Iupac: … 3-methyl-5-(6-methyl-5-{[2-(1-methyl-1H-pyrazol-4-yl)pyridin-4-yl]oxy}pyridin-2-yl)-2-[(propan-2-yl)amino …
Displaying drugs 651 - 675 of 2060 in total