Displaying drugs 651 - 675 of 4410 in total
Sotigalimab
Sotigalimab is under investigation in clinical trial NCT03123783 (CD40 Agonistic Antibody APX005M in Combination With Nivolumab).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1 (270-GLUTAMIC ACID, C-TERMINAL-LYSINE-CLIPPED), ANTI-(HUMAN CD40 ANTIGEN) (HUMAN-ORYCTOLAGUS …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
N,N-dimethylglycine
Experimental
Matched Synonyms: … N,N-Dimethylaminoacetic acid ... (dimethylamino)acetic acid ... 2-(Dimethylamino)acetic acid …
Matched Name: … N,N-dimethylglycine …
Matched Iupac: … 2-(dimethylamino)acetic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... N-substituted Glycines ... Amino Acids …
Matched Name: … N,N-dimethylglycine …
Matched Iupac: … 2-(dimethylamino)acetic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... N-substituted Glycines ... Amino Acids …
Loncastuximab tesirine
Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients who have undergone prior systemic therapies with limited success. Prognosis is poor and more effective therapies are needed to treat relapsed/refractory cases and improve survival. On April 23 2021, the Food and Drug Administration granted accelerated...
Approved
Investigational
Matched Synonyms: … immunoglobulin G1 antibody directed against human CD19 conjugated to SG3199 through A protease cleavable valine-alanine …
Matched Description: … Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients ... and improve survival. ... [A234439] Prognosis is poor and more effective therapies are needed to treat relapsed/refractory cases …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Description: … Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients ... and improve survival. ... [A234439] Prognosis is poor and more effective therapies are needed to treat relapsed/refractory cases …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
N-Dimethyl-Lysine
Experimental
Matched Name: … N-Dimethyl-Lysine …
Matched Iupac: … (2S)-2-amino-6-(dimethylamino)hexanoic acid …
Matched Iupac: … (2S)-2-amino-6-(dimethylamino)hexanoic acid …
Dodecyl creatine ester
Investigational
Matched Synonyms: … Glycine, n-(aminoiminomethyl)-n-methyl-, dodecyl ester …
Matched Iupac: … dodecyl 2-(N-methylcarbamimidamido)acetate …
Matched Iupac: … dodecyl 2-(N-methylcarbamimidamido)acetate …
N-Carbamyl-D-Valine
Experimental
Matched Name: … N-Carbamyl-D-Valine …
Matched Iupac: … (2R)-2-(carbamoylamino)-3-methylbutanoic acid …
Matched Iupac: … (2R)-2-(carbamoylamino)-3-methylbutanoic acid …
1-Naphthyl-L-alanine
Experimental
Matched Synonyms: … (S)-2-Amino-3-(naphthalen-1-yl)propanoic acid ... Naphthalen-2-yl-3-alanine ... L-beta-(1-Naphthyl)alanine …
Matched Name: … 1-Naphthyl-L-alanine …
Matched Iupac: … (2S)-2-amino-3-(naphthalen-1-yl)propanoic acid …
Matched Name: … 1-Naphthyl-L-alanine …
Matched Iupac: … (2S)-2-amino-3-(naphthalen-1-yl)propanoic acid …
Selenium
Selenium is a trace metal in the human body particularly important as a component of glutathione peroxidase, an important enzyme in the prevention of cellular damage by free radicals and reactive oxygen species [FDA Label]
Approved
Investigational
Vet approved
Matched Description: … of glutathione peroxidase, an important enzyme in the prevention of cellular damage by free radicals and …
Matched Mixtures name: … ADDAMEL N ... Multi Nt-OX ... 21ST CENTURY SELENIUM `N` ACE TABLET …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition …
Matched Products: … Selenious Acid …
Matched Mixtures name: … ADDAMEL N ... Multi Nt-OX ... 21ST CENTURY SELENIUM `N` ACE TABLET …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition …
Matched Products: … Selenious Acid …
D-arginine
A D-α-amino acid that is the D-isomer of arginine (only the L-form is physiologically active).
Experimental
Matched Synonyms: … D-Arginin ... D-2-Amino-5-guanidinovaleric acid ... (2R)-2-amino-5-guanidinopentanoic acid …
Matched Name: … D-arginine …
Matched Iupac: … (2R)-2-amino-5-carbamimidamidopentanoic acid …
Matched Description: … A D-α-amino acid that is the D-isomer of arginine (only the L-form is physiologically active). …
Matched Name: … D-arginine …
Matched Iupac: … (2R)-2-amino-5-carbamimidamidopentanoic acid …
Matched Description: … A D-α-amino acid that is the D-isomer of arginine (only the L-form is physiologically active). …
N-[1H-INDOL-3-YL-ACETYL]VALINE ACID
Experimental
Matched Name: … N-[1H-INDOL-3-YL-ACETYL]VALINE ACID …
Matched Iupac: … (2S)-2-[2-(1H-indol-3-yl)acetamido]-3-methylbutanoic acid …
Matched Iupac: … (2S)-2-[2-(1H-indol-3-yl)acetamido]-3-methylbutanoic acid …
Folitixorin
Investigational
Matched Synonyms: … L-glutamic acid, n-(4-(3-amino-1,2,5,6,6a,7-hexahydro-1-oxoimidazo(1,5-f)pteridin-8(9h)-yl)benzoyl)- ... N5,n10-methylenetetrahydrofolic acid ... Folic acid, tetrahydro-n5,n10-methylene- …
Matched Iupac: … 4-{3-amino-1-oxo-1H,2H,5H,6H,6aH,7H,8H,9H-imidazo[1,5-f]pteridin-8-yl}phenyl)formamido]pentanedioic acid …
Matched Categories: … Enzymes and Coenzymes …
Matched Iupac: … 4-{3-amino-1-oxo-1H,2H,5H,6H,6aH,7H,8H,9H-imidazo[1,5-f]pteridin-8-yl}phenyl)formamido]pentanedioic acid …
Matched Categories: … Enzymes and Coenzymes …
Clopidogrel
Clopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and stroke.[A180508,L7213] Clopidogrel is indicated to reduce the risk of myocardial infarction for patients with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and in recent MI, stroke, or established peripheral...
Approved
Matched Iupac: … methyl (2S)-2-(2-chlorophenyl)-2-{4H,5H,6H,7H-thieno[3,2-c]pyridin-5-yl}acetate …
Matched Description: … Clopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and ... elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and in recent ... be superior to [aspirin] in reducing cardiovascular outcomes in patients with cardiovascular disease and …
Matched Mixtures name: … CLOPIDOGREL E ACIDO ACETILSALICILICO VIATRIS ... CLOPIDOGREL E ACIDO ACETILSALICILICO VIATRIS ... Clopidogrel/acetylsalicylic Acid Mylan …
Matched Salts name: … Clopidogrel hydrochloride …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … Nra-clopidogrel ... CLOPIDOGREL HEUMA 75MG NET ... CLOPIDOGREL ACINO …
Matched Description: … Clopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and ... elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and in recent ... be superior to [aspirin] in reducing cardiovascular outcomes in patients with cardiovascular disease and …
Matched Mixtures name: … CLOPIDOGREL E ACIDO ACETILSALICILICO VIATRIS ... CLOPIDOGREL E ACIDO ACETILSALICILICO VIATRIS ... Clopidogrel/acetylsalicylic Acid Mylan …
Matched Salts name: … Clopidogrel hydrochloride …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … Nra-clopidogrel ... CLOPIDOGREL HEUMA 75MG NET ... CLOPIDOGREL ACINO …
Pyridoxyl-Glutamic Acid-5'-Monophosphate
Experimental
Matched Name: … Pyridoxyl-Glutamic Acid-5'-Monophosphate …
Prednicarbate
Prednicarbate is a relatively new topical corticosteroid drug that displays a similar potency as hydrocortisone. It is used in the treatment of inflammatory skin diseases, such as atopic dermatitis. It has a favorable benefit-risk ratio, with an inflammatory action similar to that of a medium potency corticosteroid, but with a...
Approved
Investigational
Matched Description: … IL-1a is also found in fibroblasts, where it is responsible for proliferation, collagenase induction and ... Prednicarbate is a relatively new topical corticosteroid drug that displays a similar potency as [hydrocortisone …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … PREDNICARBAT ACIS CREME ... PREDNICARBAT ACIS SALBE ... PREDNICARBAT ACIS FETTSALB …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … PREDNICARBAT ACIS CREME ... PREDNICARBAT ACIS SALBE ... PREDNICARBAT ACIS FETTSALB …
Sargramostim
Sargramostim is a human recombinant granulocyte macrophage colony-stimulating factor (GM-CSF) expressed in yeast. It is a glycoprotein that is 127 residues. Substitution of Leu23 leads to a difference from native protein.
Approved
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Products: … Leukine …
Matched Products: … Leukine …
Verapamil
Verapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and angina, and was the first calcium channel antagonist to be introduced into therapy in the early 1960s. It is a member of the non-dihydropyridine class of calcium channel blockers, which includes drugs...
Approved
Matched Description: … phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and ... angina,[L8791] and was the first calcium channel antagonist to be introduced into therapy in the early ... drugs like [diltiazem] and [flunarizine], but is chemically unrelated to other cardioactive medications …
Matched Mixtures name: … Trandolapril and Verapamil Hydrochloride ... Trandolapril and Verapamil Hydrochloride ... Trandolapril and Verapamil Hydrochloride …
Matched Salts name: … Verapamil hydrochloride …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... Verapamil and analogues ... trandolapril and verapamil …
Matched Products: … VERAPAMIL ACIS 240MG RETAR ... Verapamil Hydrochloride ... Verapamil hydrochloride …
Matched Mixtures name: … Trandolapril and Verapamil Hydrochloride ... Trandolapril and Verapamil Hydrochloride ... Trandolapril and Verapamil Hydrochloride …
Matched Salts name: … Verapamil hydrochloride …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... Verapamil and analogues ... trandolapril and verapamil …
Matched Products: … VERAPAMIL ACIS 240MG RETAR ... Verapamil Hydrochloride ... Verapamil hydrochloride …
Triphosphoric acid
Used as water softener, peptizing agent, emulsifier & dispersing agent; ingredient of cleansers; meat preservative.
Experimental
Matched Synonyms: … acide triphosphorique ... catena-triphosphoric acid ... tripolyphosphoric acid …
Matched Name: … Triphosphoric acid …
Matched Iupac: … {[hydroxy(phosphonooxy)phosphoryl]oxy}phosphonic acid …
Matched Categories: … Acids ... Phosphoric Acids ... Acids, Noncarboxylic ... Phosphorus Acids …
Matched Name: … Triphosphoric acid …
Matched Iupac: … {[hydroxy(phosphonooxy)phosphoryl]oxy}phosphonic acid …
Matched Categories: … Acids ... Phosphoric Acids ... Acids, Noncarboxylic ... Phosphorus Acids …
D-Cysteine
A thiol-containing non-essential amino acid that is oxidized to form CYSTINE.
Experimental
Matched Synonyms: … D-Cystein ... (2S)-2-amino-3-mercaptopropanoic acid ... D-Amino-3-mercaptopropionic acid …
Matched Name: … D-Cysteine …
Matched Iupac: … (2S)-2-amino-3-sulfanylpropanoic acid …
Matched Description: … A thiol-containing non-essential amino acid that is oxidized to form CYSTINE. …
Matched Salts name: … D-Cysteine hydrochloride monohydrate …
Matched Name: … D-Cysteine …
Matched Iupac: … (2S)-2-amino-3-sulfanylpropanoic acid …
Matched Description: … A thiol-containing non-essential amino acid that is oxidized to form CYSTINE. …
Matched Salts name: … D-Cysteine hydrochloride monohydrate …
Lactic acid
A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed) Sodium lactate is the sodium salt of lactic acid, and has a mild saline taste. It is produced by fermentation of a sugar source, such as...
Approved
Vet approved
Matched Synonyms: … Milk acid ... Lactic acid ... Acidum lacticum …
Matched Name: … Lactic acid …
Matched Iupac: … 2-hydroxypropanoic acid …
Matched Description: … (From Stedman, 26th ed) Sodium lactate is the sodium salt of lactic acid, and has a mild saline taste ... Lactic acid was one of active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved ... It is produced by fermentation of a sugar source, such as corn or beets, and then, by neutralizing the …
Matched Mixtures name: … Dextrose and Electrolyte No. 75 ... Dextrose and Electrolyte No. 48 ... Lactic Acid 30% / Salicylic Acid 30% …
Matched Categories: … Basic Ointments and Protectants ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Carboxylic Acids ... Hydroxy Acids …
Matched Products: … Lactic Acid …
Matched Name: … Lactic acid …
Matched Iupac: … 2-hydroxypropanoic acid …
Matched Description: … (From Stedman, 26th ed) Sodium lactate is the sodium salt of lactic acid, and has a mild saline taste ... Lactic acid was one of active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved ... It is produced by fermentation of a sugar source, such as corn or beets, and then, by neutralizing the …
Matched Mixtures name: … Dextrose and Electrolyte No. 75 ... Dextrose and Electrolyte No. 48 ... Lactic Acid 30% / Salicylic Acid 30% …
Matched Categories: … Basic Ointments and Protectants ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Carboxylic Acids ... Hydroxy Acids …
Matched Products: … Lactic Acid …
ST-101
ST-101 is a small peptide antagonist of C/EBPβ and T-type calcium channel activator. ST101 has been used in trials studying the treatment of Essential Tremor and Alzheimer's Disease.
Investigational
Matched Synonyms: … ST-101 (D-AMINO ACID PEPTIDE) ... -D-leucyl-D-glutaminyl-D-arginine ... D-Arginine, D-valyl-D-alanyl-D-α-glutamyl-D-alanyl-D-arginyl-D-α-glutamyl-D-α-glutamyl-D-leucyl-D-α-glutamyl-D-arginyl-D-leucyl-D-α-glutamyl-D-alanyl-D-arginyl-D-leucylglycyl-D-glutaminyl-D-alanyl-D-arginylglycyl-D-α-glutamyl-D-leucyl-D-lysyl-D-lys …
Matched Description: … ST-101 is a small peptide antagonist of C/EBPβ and T-type calcium channel activator. ... ST101 has been used in trials studying the treatment of Essential Tremor and Alzheimer's Disease. …
Matched Description: … ST-101 is a small peptide antagonist of C/EBPβ and T-type calcium channel activator. ... ST101 has been used in trials studying the treatment of Essential Tremor and Alzheimer's Disease. …
Vadadustat
One of the most common symptoms of advanced renal disease is anemia, caused primarily by the inability of the kidney to respond to anemic conditions with a corresponding increase in erythropoietin (EPO) production. The treatment of anemia associated with chronic kidney disease (CKD) has traditionally involved the administration of exogenous...
Approved
Investigational
Matched Synonyms: … N-(5-(3-Chlorophenyl)-3-hydroxypyridine-2-carbonyl)glycine ... Glycine, N-((5-(3-chlorophenyl)-3-hydroxy-2-pyridinyl)carbonyl)- …
Matched Iupac: … 2-{[5-(3-chlorophenyl)-3-hydroxypyridin-2-yl]formamido}acetic acid …
Matched Description: … [A244165] Vadadustat is an orally administered inhibitor of HIF-PH with a safety and efficacy profile ... [A244165] A relatively new and alternative treatment option for patients with anemia associated with ... efficacious, the overuse of ESAs has been associated with cardiovascular complications, progression of CKD, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Amino Acids ... Acids, Heterocyclic ... Hypoxia-Inducible Factor-Proline Dioxygenases, antagonists & inhibitors …
Matched Iupac: … 2-{[5-(3-chlorophenyl)-3-hydroxypyridin-2-yl]formamido}acetic acid …
Matched Description: … [A244165] Vadadustat is an orally administered inhibitor of HIF-PH with a safety and efficacy profile ... [A244165] A relatively new and alternative treatment option for patients with anemia associated with ... efficacious, the overuse of ESAs has been associated with cardiovascular complications, progression of CKD, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Amino Acids ... Acids, Heterocyclic ... Hypoxia-Inducible Factor-Proline Dioxygenases, antagonists & inhibitors …
Liraglutide
Victoza contains liraglutide, a synthetic analog of human glucagon-like peptide-1(GLP-1) and acts as a GLP-1 receptor agonist.[Label,A6932] Liraglutide is 97% similar to native human GLP-1, differing primarily by substituting arginine for lysine at position 34. Liraglutide is made by attaching a C-16 fatty acid (palmitic acid) with a glutamic acid...
Approved
Matched Synonyms: … N²⁶-(N-Hexadecanoyl-L-gamma-glutamyl)-[34-L-arginine]glucagon-like peptide 1-(7-37)-peptide ... N²⁶-(hexadecanoyl-gamma-glutamyle)-[34-arginine]GLP-1-(7-37)-peptide ... Arg34Lys26-(N-ε-(γ-Glu(N-α-hexadecanoyl)))-GLP-1[7-37] …
Matched Description: … Victoza contains liraglutide, a synthetic analog of human glucagon-like peptide-1(GLP-1) and acts as ... [A6932] Liraglutide is made by attaching a C-16 fatty acid (palmitic acid) with a glutamic acid spacer ... for lysine at position 34. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... insulin degludec and liraglutide ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … Victoza contains liraglutide, a synthetic analog of human glucagon-like peptide-1(GLP-1) and acts as ... [A6932] Liraglutide is made by attaching a C-16 fatty acid (palmitic acid) with a glutamic acid spacer ... for lysine at position 34. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... insulin degludec and liraglutide ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Ezatiostat
Ezatiostat is investigated in clinical trials for treating myelodysplastic syndrome. This compound belongs to the peptides. These are compounds containing an amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen...
Investigational
Matched Synonyms: … gamma-Glutamyl-S-(benzyl)-cysteinyl-R(-)-phenylglycine diethyl ester …
Matched Description: … These are compounds containing an amide derived from two or more amino carboxylic acid molecules (the ... Ezatiostat has myelostimulant activity in preclinical rodent models and human bone marrow cultures, and ... differentiates granulocytes and monocytes in HL60 cells. …
Matched Salts name: … Ezatiostat hydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … These are compounds containing an amide derived from two or more amino carboxylic acid molecules (the ... Ezatiostat has myelostimulant activity in preclinical rodent models and human bone marrow cultures, and ... differentiates granulocytes and monocytes in HL60 cells. …
Matched Salts name: … Ezatiostat hydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins …
N(2)-(2-carboxyethyl)-L-arginine
Experimental
Matched Synonyms: … L-N2-(2-Carboxyethyl)arginine ... N2-(2-carboxyethyl)arginine ... N2-(2-Carboxyethyl)-L-arginine …
Matched Name: … N(2)-(2-carboxyethyl)-L-arginine …
Matched Iupac: … (2S)-5-carbamimidamido-2-[(2-carboxyethyl)amino]pentanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Basic ... Amino Acids, Diamino …
Matched Name: … N(2)-(2-carboxyethyl)-L-arginine …
Matched Iupac: … (2S)-5-carbamimidamido-2-[(2-carboxyethyl)amino]pentanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Basic ... Amino Acids, Diamino …
N-[1H-INDOL-3-YL-ACETYL]GLYCINE ACID
Experimental
Matched Name: … N-[1H-INDOL-3-YL-ACETYL]GLYCINE ACID …
Matched Iupac: … 2-[2-(1H-indol-3-yl)acetamido]acetic acid …
Matched Iupac: … 2-[2-(1H-indol-3-yl)acetamido]acetic acid …
Displaying drugs 651 - 675 of 4410 in total