Displaying drugs 651 - 675 of 1131 in total
Metformin
Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes.[L12207,A176173]
Metformin is considered an antihyperglycemic drug because it lowers blood glucose concentrations in type II diabetes without causing hypoglycemia. It is commonly described as an "insulin sensitizer", leading to a decrease in insulin...
Approved
Matched Description: … Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management ... It is commonly described as an "insulin sensitizer", leading to a decrease in insulin resistance and ... [A36559]
Metformin was first approved in Canada in 1972,[A36552] and received subsequent FDA approval …
Matched Mixtures name: … Glipizide and Metformin Hydrochloride ... Glipizide and Metformin Hydrochloride ... Glipizide and Metformin Hydrochloride …
Matched Salts name: … Metformin hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and ertugliflozin ... metformin and sulfonylureas ... metformin and gemigliptin ... metformin and linagliptin …
Matched Products: … Glycon ... Metformin Hydrochloride ... Metformin hydrochloride …
Matched Mixtures name: … Glipizide and Metformin Hydrochloride ... Glipizide and Metformin Hydrochloride ... Glipizide and Metformin Hydrochloride …
Matched Salts name: … Metformin hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and ertugliflozin ... metformin and sulfonylureas ... metformin and gemigliptin ... metformin and linagliptin …
Matched Products: … Glycon ... Metformin Hydrochloride ... Metformin hydrochloride …
Histamine glutarimide
Histamine glutarimide is under investigation in clinical trial NCT03450434 (XC8 in the Treatment of Patients With Bronchial Asthma).
Investigational
Matched Name: … Histamine glutarimide …
Matched Description: … Histamine glutarimide is under investigation in clinical trial NCT03450434 (XC8 in the Treatment of Patients …
Matched Description: … Histamine glutarimide is under investigation in clinical trial NCT03450434 (XC8 in the Treatment of Patients …
Aluminium glycinate
Experimental
Matched Synonyms: … Aluminum glycinate …
Matched Name: … Aluminium glycinate …
Matched Categories: … aluminium glycinate ... Alimentary Tract and Metabolism ... Aluminum and magnesium containing antacids ... Amino Acids, Peptides, and Proteins …
Matched Name: … Aluminium glycinate …
Matched Categories: … aluminium glycinate ... Alimentary Tract and Metabolism ... Aluminum and magnesium containing antacids ... Amino Acids, Peptides, and Proteins …
Palonosetron
Palonosetron (INN, trade name Aloxi) is an antagonist of 5-HT3 receptors that is indicated for the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). It is the most effective of the 5-HT3 antagonists in controlling delayed CINV nausea and vomiting that appear more than 24 hours after the first...
Approved
Investigational
Matched Description: … treatment of chemotherapy-induced nausea and vomiting (CINV). ... Food and Drug Administration. ... Palonosetron (INN, trade name Aloxi) is an antagonist of 5-HT3 receptors that is indicated for the prevention and …
Matched Salts name: … Palonosetron hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... Antiemetics and Antinauseants …
Matched Products: … Palonosetron Hydrochloride ... Palonosetron hydrochloride ... PALONOSETRON HYDROCHLORIDE …
Matched Salts name: … Palonosetron hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... Antiemetics and Antinauseants …
Matched Products: … Palonosetron Hydrochloride ... Palonosetron hydrochloride ... PALONOSETRON HYDROCHLORIDE …
Cyclo(his-pro)
Experimental
Matched Synonyms: … Histidyl-proline diketopiperazine ... Histidyl-proline-diketopiperazine …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
S-Nitrosoglutathione
Investigational
Matched Synonyms: … Glycine, n-(n-l-.gamma.-glutamyl-s-nitroso-l-cysteinyl)- …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Lisinopril
Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and myocardial infarction.[L8384,L8387,L8390] Lisinopril and captopril are the only ACEIs that are not prodrugs. It functions by inhibition of angiotensin converting enzyme as well as the renin angiotensin aldosterone system.[A184781,A184808,A184817] ACEIs are commonly used as a...
Approved
Investigational
Matched Synonyms: … [N2-[(S)-1-carboxy-3-phenylpropyl]-L-lysyl-L-proline ... (S)-1-(N(2)-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline …
Matched Description: … Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and ... [L8384,L8387,L8390] Lisinopril and [captopril] are the only ACEIs that are not prodrugs. …
Matched Mixtures name: … Lisinopril and Hydrochlorothiazide ... Lisinopril and Hydrochlorothiazide ... Lisinopril and Hydrochlorothiazide …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... ACE Inhibitors and Diuretics ... Amino Acids, Peptides, and Proteins ... lisinopril and diuretics ... lisinopril and amlodipine …
Matched Description: … Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and ... [L8384,L8387,L8390] Lisinopril and [captopril] are the only ACEIs that are not prodrugs. …
Matched Mixtures name: … Lisinopril and Hydrochlorothiazide ... Lisinopril and Hydrochlorothiazide ... Lisinopril and Hydrochlorothiazide …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... ACE Inhibitors and Diuretics ... Amino Acids, Peptides, and Proteins ... lisinopril and diuretics ... lisinopril and amlodipine …
Remifentanil
Remifentanil (marketed by Abbott as Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and adjunctive to an anaesthetic. Remifentanil is a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and causes respiratory depression and analgesia.
Approved
Matched Description: … causes respiratory depression and analgesia. ... Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and ... a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and …
Matched Salts name: … Remifentanil hydrochloride …
Matched Categories: … Fentanyl and fentanyl analogues ... Hypnotics and Sedatives …
Matched Products: … Remifentanil Hydrochloride ... SERILONE® 2MG POLVO PARA SOLUCIÓN INYECTABLE ... Remifentanil Hydrochloride for Injection …
Matched Salts name: … Remifentanil hydrochloride …
Matched Categories: … Fentanyl and fentanyl analogues ... Hypnotics and Sedatives …
Matched Products: … Remifentanil Hydrochloride ... SERILONE® 2MG POLVO PARA SOLUCIÓN INYECTABLE ... Remifentanil Hydrochloride for Injection …
Brivanib alaninate
Brivanib alaninate has been investigated for the treatment of Colorectal Cancer.
Investigational
Matched Synonyms: … Brivanib alaninate …
Matched Name: … Brivanib alaninate …
Matched Description: … Brivanib alaninate has been investigated for the treatment of Colorectal Cancer. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Name: … Brivanib alaninate …
Matched Description: … Brivanib alaninate has been investigated for the treatment of Colorectal Cancer. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Dibenzyl (carbonylbis{2,1-hydrazinediyl[(2S)-4-methyl-1-oxo-1,2-pentanediyl]})biscarbamate
Experimental
Matched Synonyms: … 1,5-Bis(N-benzyloxycarbonyl-L-leucinyl)carbohydrazide …
Aminohippuric acid
The glycine amide of 4-aminobenzoic acid. Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory capacity. [PubChem]
Approved
Investigational
Matched Synonyms: … N-(p-Aminobenzoyl)glycine ... N-(para-aminobenzoyl)glycine …
Matched Description: … Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory ... The glycine amide of 4-aminobenzoic acid. …
Matched Categories: … Benzamides and benzamide derivatives ... Indicators and Reagents ... Tests for Renal Function and Ureteral Injuries …
Matched Description: … Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory ... The glycine amide of 4-aminobenzoic acid. …
Matched Categories: … Benzamides and benzamide derivatives ... Indicators and Reagents ... Tests for Renal Function and Ureteral Injuries …
Daprodustat
Daprodustat is a small-molecule hypoxia-inducible factor (HIF) prolyl hydroxylase (PHD) inhibitor that was developed by GSK.[A254167,A254162] Patients with CKD cannot induce erythropoietin (EPO) production in response to hypoxia or anemia. As a potent inhibitor of PHD1, PHD2 and PHD3 (≥ 1000-fold selectivity), daprodustat stabilizes cellular HIF1α and HIF2α and the induces...
Approved
Investigational
Matched Synonyms: … Glycine, N-((1,3-dicyclohexylhexahydro-2,4,6-trioxo-5-pyrimidinyl)carbonyl)- …
Matched Description: … HIF1α and HIF2α and the induces erythropoiesis. ... As a potent inhibitor of PHD1, PHD2 and PHD3 (≥ 1000-fold selectivity), daprodustat stabilizes cellular ... non-inferior to erythropoiesis-stimulating agents regarding the change in the hemoglobin level from baseline and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Hypoxia-Inducible Factor-Proline Dioxygenases, antagonists & inhibitors …
Matched Description: … HIF1α and HIF2α and the induces erythropoiesis. ... As a potent inhibitor of PHD1, PHD2 and PHD3 (≥ 1000-fold selectivity), daprodustat stabilizes cellular ... non-inferior to erythropoiesis-stimulating agents regarding the change in the hemoglobin level from baseline and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Hypoxia-Inducible Factor-Proline Dioxygenases, antagonists & inhibitors …
Eprodisate
Eprodisate slows the decline of renal function in AA amyloidosis.
Investigational
Matched Synonyms: … Propane-1,3-disulfonate ... Propane-1,3-disulphonate ... Propane-1,3-disulfonic acid …
Matched Iupac: … propane-1,3-disulfonic acid …
Matched Iupac: … propane-1,3-disulfonic acid …
Epitalon
Investigational
Matched Synonyms: … Glycine, l-alanyl-l-.alpha.-glutamyl-l-.alpha.-aspartyl- …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
[2,4,6-Triisopropyl-Phenylsulfonyl-L-[3-Amidino-Phenylalanine]]-Piperazine-N'-Beta-Alanine
Experimental
Matched Name: … [2,4,6-Triisopropyl-Phenylsulfonyl-L-[3-Amidino-Phenylalanine]]-Piperazine-N'-Beta-Alanine …
Pegzilarginase
Pegzilarginase is under investigation in clinical trial NCT02488044 (A Phase 1/2 Study of AEB1102 in Patients With Arginase I Deficiency).
Investigational
Matched Synonyms: … PEG-arginase ... Optimised human arginase I ... Co-ArgI-PEG modified human arginase I …
Matched Description: … is under investigation in clinical trial NCT02488044 (A Phase 1/2 Study of AEB1102 in Patients With Arginase …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Matched Description: … is under investigation in clinical trial NCT02488044 (A Phase 1/2 Study of AEB1102 in Patients With Arginase …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
4-Hydroxy-L-Threonine-5-Monophosphate
Experimental
Matched Name: … 4-Hydroxy-L-Threonine-5-Monophosphate …
N-(carboxycarbonyl)-D-phenylalanine
N-(carboxycarbonyl)-D-phenylalanine is a solid. This compound belongs to the n-acyl-alpha amino acids. These are compounds containing an alpha amino acid which bears an acyl group at its terminal nitrogen atom. It targets the protein hypoxia-inducible factor 1-alpha inhibitor.
Experimental
Matched Name: … N-(carboxycarbonyl)-D-phenylalanine …
Matched Description: … N-(carboxycarbonyl)-D-phenylalanine is a solid. …
Matched Description: … N-(carboxycarbonyl)-D-phenylalanine is a solid. …
N(6)-(pyridoxal phosphate)-L-lysine
Experimental
Matched Synonyms: … N6-((3-Hydroxy-2-methyl-5-((phosphonooxy)methyl)-4-pyridinyl)methylene)-L-lysine …
Matched Name: … N(6)-(pyridoxal phosphate)-L-lysine …
Matched Name: … N(6)-(pyridoxal phosphate)-L-lysine …
N-[O-Phosphono-Pyridoxyl]-Isoleucine
Experimental
Matched Name: … N-[O-Phosphono-Pyridoxyl]-Isoleucine …
Displaying drugs 651 - 675 of 1131 in total