Aluminium glycinate

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

Aluminium glycinate is a medication indicated to treat heartburn, indigestion, acid reflux, ulcers, and gas.

Generic Name
Aluminium glycinate
DrugBank Accession Number
DB13626
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
Thumb
Weight
Average: 153.07
Monoisotopic: 153.0217859
Chemical Formula
C2H8AlNO5
Synonyms
  • Aluminio glicinato
  • Aluminum glycinate
  • Dihydroxyaluminum aminoacetate

Pharmacology

Indication

Not Available

Pharmacology
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Associated Conditions
Contraindications & Blackbox Warnings
Contraindications
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Adverseeffects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
AcetaminophenAluminium glycinate can cause a decrease in the absorption of Acetaminophen resulting in a reduced serum concentration and potentially a decrease in efficacy.
AcetophenazineAluminium glycinate can cause a decrease in the absorption of Acetophenazine resulting in a reduced serum concentration and potentially a decrease in efficacy.
Alendronic acidThe serum concentration of Alendronic acid can be decreased when it is combined with Aluminium glycinate.
AlimemazineAluminium glycinate can cause a decrease in the absorption of Alimemazine resulting in a reduced serum concentration and potentially a decrease in efficacy.
AllopurinolThe therapeutic efficacy of Allopurinol can be decreased when used in combination with Aluminium glycinate.
AmphetamineThe serum concentration of Amphetamine can be increased when it is combined with Aluminium glycinate.
AmprenavirAluminium glycinate can cause a decrease in the absorption of Amprenavir resulting in a reduced serum concentration and potentially a decrease in efficacy.
AsunaprevirAluminium glycinate can cause a decrease in the absorption of Asunaprevir resulting in a reduced serum concentration and potentially a decrease in efficacy.
AtazanavirAluminium glycinate can cause a decrease in the absorption of Atazanavir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Beclomethasone dipropionateThe bioavailability of Beclomethasone dipropionate can be decreased when combined with Aluminium glycinate.
Interactions
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Food Interactions
Not Available

Products

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Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
อาโมจินAluminium glycinate (250 MG) + Magnesium trisilicate (250 MG)Tabletบริษัท โมเดิร์น ฟาร์มา จำกัด2013-01-14Not applicableThailand flag

Categories

ATC Codes
A02AB07 — Aluminium glycinate
Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
DO250MG0W6
CAS number
41354-48-7
InChI Key
UTUUIUQHGDRVPU-UHFFFAOYSA-K
InChI
InChI=1S/C2H5NO2.Al.3H2O/c3-1-2(4)5;;;;/h1,3H2,(H,4,5);;3*1H2/q;+3;;;/p-3
IUPAC Name
aluminium(3+) 2-aminoacetate hydrate dihydroxide
SMILES
O.[OH-].[OH-].[Al+3].NCC([O-])=O

References

General References
  1. FDA Thailand: Amogin (Aluminum Glycinate) Oral Tablet [Link]
ChemSpider
34990037
RxNav
23162
Wikipedia
Aluminium_glycinate

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
Tablet
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility30.6 mg/mLALOGPS
logP-1.2ALOGPS
logP-3.4ChemAxon
logS-0.64ALOGPS
pKa (Strongest Acidic)2.31ChemAxon
pKa (Strongest Basic)9.24ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count3ChemAxon
Hydrogen Donor Count1ChemAxon
Polar Surface Area66.15 Å2ChemAxon
Rotatable Bond Count1ChemAxon
Refractivity26.84 m3·mol-1ChemAxon
Polarizability6.25 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Drug created on June 23, 2017 20:45 / Updated on May 29, 2021 18:12