Displaying drugs 6901 - 6925 of 8267 in total
Ontamalimab
Ontamalimab is under investigation in clinical trial NCT03627091 (Efficacy and Safety Study of SHP647 as Maintenance Treatment in Participants With Moderate to Severe Crohn's Disease (CARMEN CD 307)).
Investigational
Matched Description: … Ontamalimab is under investigation in clinical trial NCT03627091 (Efficacy and Safety Study of SHP647 …
Silmitasertib
Silmitasertib is under investigation in clinical trial NCT03904862 (Testing the Safety and Tolerability of CX-4945 in Patients With Recurrent Medulloblastoma Who May or May Not Have Surgery).
Investigational
Matched Description: … Silmitasertib is under investigation in clinical trial NCT03904862 (Testing the Safety and Tolerability of …
Zampilimab
Zampilimab is under investigation in clinical trial NCT04335578 (A Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Efficacy of UCB7858 in Adult Kidney Transplant Recipients With Chronic Allograft Injury).
Investigational
Matched Description: … clinical trial NCT04335578 (A Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Efficacy of …
Volagidemab
Volagidemab is under investigation in clinical trial NCT03117998 (Multiple Dose Study to Evaluate the Efficacy, Safety and Pharmacodynamics of REMD-477 in Subjects With Type 1 Diabetes Mellitus).
Investigational
Matched Description: … clinical trial NCT03117998 (Multiple Dose Study to Evaluate the Efficacy, Safety and Pharmacodynamics of …
MaxAdFVIII
MaxAdFVIII is an adenoviral vector that expresses the full-length human Factor VIII (hFVIII) cDNA. First developed by GenStar, it is being investigated for the treatment of hemophilia.
Investigational
Matched Description: … First developed by GenStar, it is being investigated for the treatment of hemophilia. …
RLYB212
RLYB212 is a human monoclonal antibody against Antigen-1A Immunoglobulin (HPA-1A). It is currently being developed by Rallybio for the prevention of fetal and neonatal alloimmune thrombocytopenia.
Investigational
Matched Description: … It is currently being developed by Rallybio for the prevention of fetal and neonatal alloimmune thrombocytopenia …
Bacteroides thetaiotaomicron
Bacteroides thetaiotaomicron is a live biotherapeutic. Developed by 4D Pharma, Thetanix, an oral formulation comprising lyophilized Bacteroides thetaiotaomicron, is being investigated for the treatment of Crohn’s disease.
Investigational
Matched Description: … formulation comprising lyophilized Bacteroides thetaiotaomicron, is being investigated for the treatment of …
Ispectamab debotansine
Ispectamab debotansine is an antibody drug conjugate comprised of an anti-B cell maturation (BCMA) IgG1 humanized antibody conjugated covalently to the dibenzocyclooctyne (DBCO) noncleavable linker maytansinoid warhead.
Investigational
Matched Description: … Ispectamab debotansine is an antibody drug conjugate comprised of an anti-B cell maturation (BCMA) IgG1 …
LMB-100
LMB-100 is a is an antibody-toxin conjugate with an antimesothelin Fab linked to a 24-kilodalton portion of Pseudomonas exotoxin A with mutations that decrease immunogenicity.
Investigational
Matched Description: … 100 is a is an antibody-toxin conjugate with an antimesothelin Fab linked to a 24-kilodalton portion of …
Visugromab
Visugromab is under investigation in clinical trial NCT06059547 (Neoadjuvant Immunotherapy in Combination With the Anti-gdf-15 Antibody Visugromab (CTL-002) for Treatment of Muscle Invasive Bladder Cancer).
Investigational
Matched Description: … Neoadjuvant Immunotherapy in Combination With the Anti-gdf-15 Antibody Visugromab (CTL-002) for Treatment of …
AG-858
AG-858 (autologous heat-shock protein 70 peptide vaccine) is
a recombinant cancer vaccine made with tumor-derived heat shock protein 70 (HSP70) peptide complexes. HSP70 associates with antigenic peptides, transporting them into antigen presenting cells (APC) for processing. Tumor-derived HSP70-peptide complexes used in vaccine preparations have been shown to prime tumor immunity...
Investigational
SGN-30
SGN-30 is an engineered monoclonal antibody (mAb) that reacts with significant affinity to the CD30 antigen, which is highly expressed on a variety of hematologic malignancies as compared to on normal cells. SGN-30 has been shown to induce direct anti-cancer activity towards tumor cells expressing CD30 and is undergoing phase...
Investigational
Matched Description: … ) that reacts with significant affinity to the CD30 antigen, which is highly expressed on a variety of ... with chemotherapy for the treatment of relapsed Hodgkin lymphoma, front-line ALCL and pediatric ALCL ... We are collaborating with the National Cancer Institute (NCI) on three clinical trials of SGN-30 in combination …
Picolinic acid
PCL-016 or Picolinic acid drug substance is a pyridine carboxylate metabolite of tryptophan. It acts as an anti-infective and immunomodulator and is produced in approximately 25-50 mg quantities by the body on a daily basis through the breakdown of tryptophan. PCL-016 plays a key role in zinc transport. As a...
Investigational
Matched Description: … PCL-016 or Picolinic acid drug substance is a pyridine carboxylate metabolite of tryptophan. ... is produced in approximately 25-50 mg quantities by the body on a daily basis through the breakdown of ... Acne vulgaris, herpes and other viral infections therefore pose potential therapeutic targets of PCL- …
Duvoglustat
An alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-HIV activity.
Investigational
Matched Description: … Derivatives of deoxynojirimycin may have anti-HIV activity. …
FP-1096
FP1096 reduced the painful symptoms of endometriosis in trial subjects with very minimal side effect.
Investigational
Matched Description: … FP1096 reduced the painful symptoms of endometriosis in trial subjects with very minimal side effect. …
Talaporfin
Talaporfin has been investigated for the treatment of Port-Wine Stain and Benign Prostatic Hyperplasia.
Investigational
Matched Description: … Talaporfin has been investigated for the treatment of Port-Wine Stain and Benign Prostatic Hyperplasia …
Pritelivir
Pritelivir has been used in trials studying the prevention of HSV-2 and Genital Herpes.
Investigational
Matched Description: … Pritelivir has been used in trials studying the prevention of HSV-2 and Genital Herpes. …
Riboprine
Ipa has been used in trials studying the treatment of Nausea and Surgical Site Infection.
Investigational
Matched Description: … Ipa has been used in trials studying the treatment of Nausea and Surgical Site Infection. …
AZD-4818
AZD4818 has been used in trials studying the treatment of Chronic Obstructive Pulmonary Disease (COPD).
Investigational
Matched Description: … AZD4818 has been used in trials studying the treatment of Chronic Obstructive Pulmonary Disease (COPD …
Ammonio methacrylate copolymer type A
Ammonio methacrylate copolymer type a has been used in trials studying the treatment of GERD.
Investigational
Matched Description: … Ammonio methacrylate copolymer type a has been used in trials studying the treatment of GERD. …
Vesnarinone
Vesnarinone has been used in trials studying the treatment of HIV Infections and Sarcoma, Kaposi.
Investigational
Matched Description: … Vesnarinone has been used in trials studying the treatment of HIV Infections and Sarcoma, Kaposi. …
Tricaprylin
Tricaprilin has been used in trials studying the supportive care and treatment of Alzheimer's Disease.
Investigational
Matched Description: … Tricaprilin has been used in trials studying the supportive care and treatment of Alzheimer's Disease …
Fosdagrocorat
Fosdagrocorat has been used in trials studying the treatment and basic science of Rheumatoid Arthritis.
Investigational
Matched Description: … Fosdagrocorat has been used in trials studying the treatment and basic science of Rheumatoid Arthritis …
TRV-120027
TRV120027 has been used in trials studying the treatment of Heart Failure and Kidney Disease.
Investigational
Matched Description: … TRV120027 has been used in trials studying the treatment of Heart Failure and Kidney Disease. …
Balapiravir
Balapiravir has been used in trials studying the treatment of Dengue and Hepatitis C, Chronic.
Investigational
Matched Description: … Balapiravir has been used in trials studying the treatment of Dengue and Hepatitis C, Chronic. …
Displaying drugs 6901 - 6925 of 8267 in total