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Displaying drugs 676 - 700 of 6859 in total
Deflazacort
Deflazacort, also known as Emflaza, is a corticosteroid prodrug used as an agent to manage Duchenne Muscular Dystrophy (DMD). It is marketed by Marathon Pharmaceuticals and was approved in February 2017 by the FDA.[L6694,FDA label]
Duchenne Muscular Dystrophy is an inherited disorder resulting from mutations of the dystrophin gene, which...
Approved
Investigational
Matched Iupac: … 2-[(1S,2S,4R,8S,9S,11S,12S,13R)-11-hydroxy-6,9,13-trimethyl-16-oxo-5-oxa-7-azapentacyclo[10.8.0.0²,⁹.0⁴,⁸.0¹³,¹⁸ …
Avapritinib
Avapritinib, or BLU-285, is a selective tyrosine kinase inhibitor of KIT and platelet derived growth factor receptor alpha indicated for the treatment of unresectable, metastatic gastrointestinal stromal tumors and advanced systemic mastocytosis.[A189339,L40363] It is one of the first medications available for the treatment of multidrug resistant cancers. Avapritinib shares a...
Approved
Investigational
Matched Iupac: … fluorophenyl)-1-(2-{4-[6-(1-methyl-1H-pyrazol-4-yl)pyrrolo[2,1-f][1,2,4]triazin-4-yl]piperazin-1-yl}pyrimidin-5- …
Cyanocobalamin Co-60
Cyanocobalamin Co-60 is an analog of Vitamin B12 labeled with Co60. Cyanocobalamin Co-60 was used for the diagnosis of pernicious anemia, but now it is withdrawn from the market in the US for unknown reasons.
Approved
Withdrawn
Matched Iupac: … ,18R,19R)-4,9,14-tris(2-carbamoylethyl)-3,8,19-tris(carbamoylmethyl)-18-(2-{[(2R)-2-{[(2R,3S,4R,5S)-5- ... 2,3,6,8,13,13,16,18-octamethyl-20,21,22,23-tetraazapentacyclo[15.2.1.1^{2,5}.1^{7,10}.1^{12,15}]tricosa-5( …
Trypan blue free acid
Trypan blue is a diazo dye used in ophthalmic cataract surgery to stain the anterior capsule in the presence of a mature cataract. This is done to aid in visualization before creating the continuous curvilinear capsulorhexis.
Approved
Matched Iupac: … 5-amino-3-[(E)-2-{4'-[(E)-2-(8-amino-1-hydroxy-3,6-disulfonaphthalen-2-yl)diazen-1-yl]-3,3'-dimethyl- …
Rimegepant
Rimegepant is an oral antagonist of the CGRP receptor developed by Biohaven Pharmaceuticals. It received FDA approval on February 27, 2020 for the acute treatment migraine headache, and was subsequently approved by the European Commission in April 2022 for both the treatment and prevention of migraines. While several parenteral antagonists...
Approved
Investigational
Matched Iupac: … (5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-5H,6H,7H,8H,9H-cyclohepta[b]pyridin-9-yl 4-{2-oxo-1H,2H,3H-imidazo …
Baloxavir marboxil
Baloxavir marboxil is an antiviral drug used to treat influenza. More specifically, it is a first-in-class cap-dependent endonuclease inhibitor that works to block influenza virus proliferation.[A39895, A251755] It is a prodrug of baloxavir with an improved absorption profile than its active metabolite due to the addition of a phenolic hydroxyl...
Approved
Investigational
Matched Iupac: … 2S)-12,13-difluoro-9-thiatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaen-2-yl]-9,12-dioxo-5- …
Dactinomycin
A compound composed of a two cyclic peptides attached to a phenoxazine that is derived from streptomyces parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release. As a result of impaired mRNA production, protein synthesis also declines after dactinomycin...
Approved
Investigational
Micronomicin
Micronomicin is an aminoglycoside antibiotic which is marketed in Japan, and sold under the brand names Sagamicin and Luxomicina.
Approved
Matched Iupac: … )-4,6-diamino-3-{[(2R,3R,6S)-3-amino-6-[(methylamino)methyl]oxan-2-yl]oxy}-2-hydroxycyclohexyl]oxy}-5- …
Naldemedine
Naldemedine is an opioid receptor antagonist [FDA Label]. It is a modified form of DB00704 to which a side chain has been added to increase molecular weight and polar surface area resulting in restricted transport across the blood brain barrier. Naldemedine was approved in 2017 in both the US and...
Approved
Investigational
Matched Iupac: … (1S,5R,13R,17S)-4-(cyclopropylmethyl)-10,14,17-trihydroxy-N-[2-(3-phenyl-1,2,4-oxadiazol-5-yl)propan- …
Clocortolone
Clocortolone is a medium potency corticosteroid that is often used as a topical cream for the relief of inflammatory oand pruritic (itching) arising from steroid-responsive dermatoses of the scalp.
Approved
Matched Iupac: … (1S,2R,3aS,3bS,5S,9aS,9bR,10S,11aS)-9b-chloro-5-fluoro-10-hydroxy-1-(2-hydroxyacetyl)-2,9a,11a-trimethyl …
Acetyldigitoxin
Cardioactive derivative of lanatoside A or of digitoxin used for fast digitalization in congestive heart failure.
Approved
Matched Iupac: … [(2R,3S,4S,6S)-6-{[(2R,3S,4S,6R)-6-{[(1R,3aS,3bR,5aR,7S,9aS,9bS,11aR)-3a-hydroxy-9a,11a-dimethyl-1-(5- …
Bivalirudin
Bivalirudin is a synthetic 20 residue peptide (thrombin inhibitor) which reversibly inhibits thrombin. Once bound to the active site, thrombin cannot activate fibrinogen into fibrin, the crucial step in the formation of thrombus. It is administered intravenously. Because it can cause blood stagnation, it is important to monitor changes in...
Approved
Investigational
Matched Iupac: … -2-(2-{2-[2-(2-{[(2S)-1-[(2S)-2-{[(2S)-1-[(2R)-2-amino-3-phenylpropanoyl]pyrrolidin-2-yl]formamido}-5- …
Zilucoplan
Zilucoplan is a 15 amino-acid, synthetic macrocyclic peptide. It is a complement inhibitor that works to prevent the activation of C5, which is a complement protein involved in the innate immune system to initiate inflammatory responses. On October 17, 2023, zilucoplan gained its first FDA approval for the treatment of...
Approved
Matched Iupac: … -2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-{1-[(2S,5S,8S,11S,14S,22S)-11-benzyl-8-(3-carbamimidamidopropyl)-5- …
Octocrylene
Octocrylene is a compound often used as an additive in sun screen, and is thought to have skin moisturizing effects because of its emollient properties. What makes this chemical such a popular additive to sun block, is its ability to neutralize UV radiation dissipated by sunlight, and to minimize skin...
Approved
Investigational
Matched Mixtures name: … Gold Bond Ultimate 5-in-1 Face ... Hydra-total 5 Ultra-even Lotion ... Avobenzone 3% Homosalate 10% Octisalate 5% Octocrylene 10% …
Janssen COVID-19 Vaccine
The Janssen COVID-19 vaccine (Ad26.COV2.S) is a recombinant vaccine that contains an adenovirus serotype 26 (Ad26) vector expressing a stabilized SARS-CoV-2 spike protein. The vaccine was created in collaboration with Johnson and Johnson (J&J), Janssen Pharmaceutical, and the Beth Israel Deaconess Medical Center. A preclinical study in hamsters infected with...
Approved
Investigational
Matched Name: … Janssen COVID-19 Vaccine …
Matched Description: … The Janssen COVID-19 vaccine (Ad26.COV2.S) is a recombinant vaccine that contains an adenovirus serotype ... The Janssen COVID-19 vaccine is available under an Emergency Use Authorization (EUA) in the US. …
Matched Categories: … COVID-19 Vaccines …
Matched Products: … Janssen COVID-19 Vaccine ... Covid-19 Vaccine Janssen …
Matched Description: … The Janssen COVID-19 vaccine (Ad26.COV2.S) is a recombinant vaccine that contains an adenovirus serotype ... The Janssen COVID-19 vaccine is available under an Emergency Use Authorization (EUA) in the US. …
Matched Categories: … COVID-19 Vaccines …
Matched Products: … Janssen COVID-19 Vaccine ... Covid-19 Vaccine Janssen …
5-O-phosphono-alpha-D-ribofuranosyl diphosphate
The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides.
Approved
Experimental
Investigational
Matched Synonyms: … 5-Phosphoribosyl diphosphate ... 5-Phosphoribosyl 1-pyrophosphate ... 5-Phospho-alpha-D-ribose 1-diphosphate …
Matched Name: … 5-O-phosphono-alpha-D-ribofuranosyl diphosphate …
Matched Iupac: … [({[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl]oxy}(hydroxy)phosphoryl)oxy]phosphonic …
Matched Name: … 5-O-phosphono-alpha-D-ribofuranosyl diphosphate …
Matched Iupac: … [({[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl]oxy}(hydroxy)phosphoryl)oxy]phosphonic …
Streptococcus pneumoniae type 5 capsular polysaccharide antigen
Streptococcus pneumoniae type 5 capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 5 of Streptococcus pneumoniae. It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Approved
Investigational
Matched Synonyms: … pneumococcal capsular polysaccharide type 5 vaccine …
Matched Name: … Streptococcus pneumoniae type 5 capsular polysaccharide antigen …
Matched Description: … capsular polysaccharides from the invasive pneumococcal type 5 of *Streptococcus pneumoniae*. ... Streptococcus pneumoniae type 5 capsular polysaccharide antigen is a vaccine that contains highly purified …
Matched Mixtures name: … Pneumococcal Polysaccharide Conjugate Vaccine (Adsorbed) (10-Valent) SUSPENSION FOR INJECTION (MULTIDOSE - 5 …
Matched Name: … Streptococcus pneumoniae type 5 capsular polysaccharide antigen …
Matched Description: … capsular polysaccharides from the invasive pneumococcal type 5 of *Streptococcus pneumoniae*. ... Streptococcus pneumoniae type 5 capsular polysaccharide antigen is a vaccine that contains highly purified …
Matched Mixtures name: … Pneumococcal Polysaccharide Conjugate Vaccine (Adsorbed) (10-Valent) SUSPENSION FOR INJECTION (MULTIDOSE - 5 …
Tozinameran
The Pfizer-BioNTech COVID-19 vaccine (also known as BNT162b2, Tozinameran, and Comirnaty), is one of four advanced mRNA-based vaccines developed through "Project Lightspeed," a joint program between Pfizer and BioNTech.[L15002,L15007,L36025] Comirnaty is a nucleoside modified mRNA (modRNA) vaccine encoding an optimized full-length version of the severe acute respiratory syndrome coronavirus 2...
Approved
Investigational
Matched Synonyms: … Pfizer-BioNTech COVID-19 Vaccine …
Matched Description: … The Pfizer-BioNTech COVID-19 vaccine (also known as BNT162b2, Tozinameran, and Comirnaty), is one of ... It is designed to induce immunity against SARS-CoV-2, the virus responsible for causing COVID-19. ... Currently, sufficient data are not available to determine the longevity of protection against COVID-19 …
Matched Mixtures name: … Comirnaty Original & Omicron Ba.4/ba.5 ... Comirnaty Original & Omicron Ba.4/ba.5 ... Comirnaty Original & Omicron Ba.4/ba.5 …
Matched Categories: … COVID-19 Vaccines …
Matched Products: … Pfizer-BioNTech Covid-19 Vaccine …
Matched Description: … The Pfizer-BioNTech COVID-19 vaccine (also known as BNT162b2, Tozinameran, and Comirnaty), is one of ... It is designed to induce immunity against SARS-CoV-2, the virus responsible for causing COVID-19. ... Currently, sufficient data are not available to determine the longevity of protection against COVID-19 …
Matched Mixtures name: … Comirnaty Original & Omicron Ba.4/ba.5 ... Comirnaty Original & Omicron Ba.4/ba.5 ... Comirnaty Original & Omicron Ba.4/ba.5 …
Matched Categories: … COVID-19 Vaccines …
Matched Products: … Pfizer-BioNTech Covid-19 Vaccine …
Norethisterone
Norethisterone, also known as norethindrone, is a synthetic progestational hormone belonging to the 19-nortestosterone-derived class of progestins. It is further classified as a second-generation progestin, along with levonorgestrel and its derivatives, and is the active form of several other progestins including norethynodrel and lynestrenol. Norethisterone mimics the actions of endogenous...
Approved
Matched Synonyms: … 19-nor-ethindrone ... 19-norethisterone ... 17-α-ethynyl-19-nortestosterone …
Matched Description: … Norethisterone, also known as norethindrone, is a synthetic progestational hormone belonging to the 19 …
Matched Products: … SUNOLUT TABLET 5 mg ... NORCOLUT TABLET 5 mg ... NORCUTIN TABLET 5 MG …
Matched Description: … Norethisterone, also known as norethindrone, is a synthetic progestational hormone belonging to the 19 …
Matched Products: … SUNOLUT TABLET 5 mg ... NORCOLUT TABLET 5 mg ... NORCUTIN TABLET 5 MG …
Nandrolone decanoate
Nandrolone decanoate, also known as nandrolone caprinate, is an alkylated anabolic steroid indicated in the management of anemia of renal insufficiency and as an adjunct therapy in the treatment of senile and postmenopausal osteoporosis.[A233789,A233849,L32564,L9464] The process for creating esters of nandrolone was patented in Spain in 1959 and in 1960,...
Approved
Illicit
Matched Synonyms: … 19-nortestosterone decanoate …
Matched Description: … [A233849] Nandrolone decanoate was granted FDA approval on 5 October 1962.[L32564] …
Matched Products: … PARABOLIN RETARD 5 MG AMPUL, 2 ADET …
Matched Description: … [A233849] Nandrolone decanoate was granted FDA approval on 5 October 1962.[L32564] …
Matched Products: … PARABOLIN RETARD 5 MG AMPUL, 2 ADET …
Tibolone
Tibolone is a synthetic steroid hormone drug, which is mainly non-selective in its binding profile, acting as an agonist primarily at estrogen receptors (ER), with a preference for ER alpha .
Tibolone (Livial, Org OD 14), produced by Organon (West Orange, NJ), is a synthetic steroid that possesses estrogenic, androgenic...
Approved
Investigational
Matched Synonyms: … 17-hydroxy-7alpha-methyl-19-nor-17alpha-pregn-5(10)-en-20-yn-3-one …
Matched Iupac: … 9R,10R,11S,14R,15S)-14-ethynyl-14-hydroxy-9,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-2(7)-en-5- …
Matched Iupac: … 9R,10R,11S,14R,15S)-14-ethynyl-14-hydroxy-9,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-2(7)-en-5- …
Paricalcitol
Paricalcitol is a synthetic vitamin D analog. Paricalcitol has been used to reduce parathyroid hormone levels. Paricalcitol is indicated for the prevention and treatment of secondary hyperparathyroidism associated with chronic renal failure.
Approved
Investigational
Matched Synonyms: … 19-Nor-1alpha,25-dihydroxyvitamin D2 …
Matched Iupac: … (1R,3R)-5-{2-[(1R,3aS,4E,7aR)-1-[(2R,3E,5S)-6-hydroxy-5,6-dimethylhept-3-en-2-yl]-7a-methyl-octahydro …
Matched Products: … PAKSİTU 5 MCG/ML ENJEKSİYONLUK ÇÖZELTİ, 5 ADET ... RECHROSİTOL 5 MCG/ML I.V. ENJEKSİYONLUK ÇÖZELTİ, 5 ADET ... PARİTOLİN 5 MCG/ML I.V. ENJEKSİYONLUK ÇÖZELTİ, 5 ADET …
Matched Iupac: … (1R,3R)-5-{2-[(1R,3aS,4E,7aR)-1-[(2R,3E,5S)-6-hydroxy-5,6-dimethylhept-3-en-2-yl]-7a-methyl-octahydro …
Matched Products: … PAKSİTU 5 MCG/ML ENJEKSİYONLUK ÇÖZELTİ, 5 ADET ... RECHROSİTOL 5 MCG/ML I.V. ENJEKSİYONLUK ÇÖZELTİ, 5 ADET ... PARİTOLİN 5 MCG/ML I.V. ENJEKSİYONLUK ÇÖZELTİ, 5 ADET …
Andusomeran
Andusomeran is a COVID-19 mRNA vaccine developed for use during the 2023-2024 season.[L40074,L48832,L48837] It is similar to previous mRNA vaccines developed by Moderna (e.g. elasomeran, imelasomeran), but is designed to be effective against the Omicron XBB.1.5 subvariant.
Approved
Matched Synonyms: … COVID-19 mRNA vaccine, monovalent (XBB.1.5 Variant) …
Matched Description: … Andusomeran is a COVID-19 mRNA vaccine developed for use during the 2023-2024 season. …
Matched Categories: … COVID-19 Vaccines …
Matched Products: … Moderna COVID-19 Vaccine …
Matched Description: … Andusomeran is a COVID-19 mRNA vaccine developed for use during the 2023-2024 season. …
Matched Categories: … COVID-19 Vaccines …
Matched Products: … Moderna COVID-19 Vaccine …
Nomegestrol acetate
Nomegestrol acetate, also known as NOMAC, is a progestin used in oral contraceptives, menopausal hormone therapy, and for the treatment of gynecological disorders.
Approved
Investigational
Matched Synonyms: … 17-alpha-Acetoxy-6-methyl-19-nor-4,6-pregnadiene-3,20-dione ... 17-alpha-Hydroxy-6-methyl-19-norpregna-4,6-diene-3,20-dione acetate …
Segesterone acetate
Segesterone acetate is a steroidal progestin or synthetic progesterone and a 19-norprogesterone derivative with no CH3 group radical in position 6 . In animal studies, segesterone acetate was shown to be one of the most potent progestins . It mediates progestational activity 100 times higher than that of progesterone ....
Approved
Experimental
Investigational
Matched Synonyms: … 16-Methylene-17-alpha-acetoxy-19-nor-4-pregnene-3,20-dione ... 17-Hydroxy-16-methylene-19-norpregn-4-ene-3,20-dione acetate …
Matched Description: … Segesterone acetate is a steroidal progestin or synthetic progesterone and a 19-norprogesterone derivative …
Matched Description: … Segesterone acetate is a steroidal progestin or synthetic progesterone and a 19-norprogesterone derivative …
Displaying drugs 676 - 700 of 6859 in total