Displaying drugs 676 - 700 of 2683 in total
Cyclothiazide
As a diuretic, cyclothiazide inhibits active chloride reabsorption at the early distal tubule via the Na-Cl cotransporter, resulting in an increase in the excretion of sodium, chloride, and water. Thiazides like cyclothiazide also inhibit sodium ion transport across the renal tubular epithelium through binding to the thiazide sensitive sodium-chloride transporter....
Approved
Matched International brands: … Anhydron …
Matched Description: … Na-Cl cotransporter, resulting in an increase in the excretion of sodium, chloride, and water. ... corticosteroid and estrogen therapy. ... indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... cyclothiazide and potassium …
Matched Description: … Na-Cl cotransporter, resulting in an increase in the excretion of sodium, chloride, and water. ... corticosteroid and estrogen therapy. ... indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... cyclothiazide and potassium …
Grazoprevir
Grazoprevir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Matched Synonyms: … Grazoprevir anhydrous …
Matched Description: … Subtitutions at amino acid positions 155, 156, or 168 are known to confer resistance. ... with or without [DB00811] depending on the the presence of resistance associated amino acid substitutions ... to achieve a SVR between 94% and 97% for genotype 1 and 97% and 100% for genotype 4 after 12 weeks of …
Matched Categories: … elbasvir and grazoprevir ... Acids, Acyclic ... Carboxylic Acids …
Matched Description: … Subtitutions at amino acid positions 155, 156, or 168 are known to confer resistance. ... with or without [DB00811] depending on the the presence of resistance associated amino acid substitutions ... to achieve a SVR between 94% and 97% for genotype 1 and 97% and 100% for genotype 4 after 12 weeks of …
Matched Categories: … elbasvir and grazoprevir ... Acids, Acyclic ... Carboxylic Acids …
Navarixin
Navarixin has been investigated for the treatment of Asthma.
Investigational
Matched Synonyms: … Navarixin anhydrous …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Peramivir
Peramivir is an antiviral agent developed by Biocryst Pharmaceuticals to treat influenza A/B. The development of peramivir has been supported by the US Department of Health and Human Services as part of the government's effort to prepare for a flu pandemic. Being an influenza virus neuraminidase inhibitor, peramivir works by...
Approved
Investigational
Matched Synonyms: … Peramivir anhydrous …
Matched Iupac: … 1S,2S,3R,4R)-4-carbamimidamido-3-[(1S)-1-acetamido-2-ethylbutyl]-2-hydroxycyclopentane-1-carboxylic acid …
Matched Description: … The development of peramivir has been supported by the US Department of Health and Human Services as ... the poor oral bioavailability, the oral formulation of the drug was previously abandoned by Johnson and ... in September 2017 for the treatment of acute uncomplicated influenza to pediatric patients 2 years and …
Matched Categories: … Carboxylic Acids …
Matched Iupac: … 1S,2S,3R,4R)-4-carbamimidamido-3-[(1S)-1-acetamido-2-ethylbutyl]-2-hydroxycyclopentane-1-carboxylic acid …
Matched Description: … The development of peramivir has been supported by the US Department of Health and Human Services as ... the poor oral bioavailability, the oral formulation of the drug was previously abandoned by Johnson and ... in September 2017 for the treatment of acute uncomplicated influenza to pediatric patients 2 years and …
Matched Categories: … Carboxylic Acids …
Dideoxyadenosine
Investigational
Matched Synonyms: … -d-glycero-pentofuranosyl)purine ... -d-glycero-pentofuranosyl)-9h-purin-6-amine …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Orange
Orange allergenic extract is used in allergenic testing.
Approved
Matched Products: … Food - Plant Source, Orange Citrus sinensis …
(2R)-2-Acetamido-3-(octadecyloxy)propyl 2-(methylsulfanyl)ethyl hydrogen phosphate
Experimental
Matched Synonyms: … 1-Octadecyl-2-acetamido-2-deoxy-SN-glycerol-3-phosphoethylmethyl sulfide …
Matched Iupac: … [(2R)-2-acetamido-3-(octadecyloxy)propoxy][2-(methylsulfanyl)ethoxy]phosphinic acid …
Matched Iupac: … [(2R)-2-acetamido-3-(octadecyloxy)propoxy][2-(methylsulfanyl)ethoxy]phosphinic acid …
Clopidogrel
Clopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and stroke.[A180508,L7213] Clopidogrel is indicated to reduce the risk of myocardial infarction for patients with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and in recent MI, stroke, or established peripheral...
Approved
Matched Description: … Clopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and ... with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and ... be superior to [aspirin] in reducing cardiovascular outcomes in patients with cardiovascular disease and …
Matched Mixtures name: … Clopidogrel/acetylsalicylic Acid Mylan ... Clopidogrel/acetylsalicylic Acid Mylan ... Clopidogrel/acetylsalicylic Acid Mylan …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … CLOPIDOGREL ACINO ... Clopidogrel Acino ... CLOPIDOGREL ACINO PHARMA …
Matched Mixtures name: … Clopidogrel/acetylsalicylic Acid Mylan ... Clopidogrel/acetylsalicylic Acid Mylan ... Clopidogrel/acetylsalicylic Acid Mylan …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … CLOPIDOGREL ACINO ... Clopidogrel Acino ... CLOPIDOGREL ACINO PHARMA …
Tiaprofenic acid
Tiaprofenic acid is a non-steroidal anti-inflammatory drug employed in the treatment of pain, particularly arthritis pain. It belongs to the arylpropionic acid (profen) group of nonsteroidal anti-inflammatory drugs (NSAIDs).
Approved
Matched Synonyms: … Tiaprofenic acid ... Acido tiaprofenico ... Acide tiaprofenique …
Matched Name: … Tiaprofenic acid …
Matched Iupac: … 2-(5-benzoylthiophen-2-yl)propanoic acid …
Matched Description: … Tiaprofenic acid is a non-steroidal anti-inflammatory drug employed in the treatment of pain, particularly ... It belongs to the _arylpropionic acid_ (profen) group of nonsteroidal anti-inflammatory drugs (NSAIDs …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Acids, Acyclic ... Fatty Acids ... Carboxylic Acids …
Matched Products: … Teva-tiaprofenic Acid …
Matched Name: … Tiaprofenic acid …
Matched Iupac: … 2-(5-benzoylthiophen-2-yl)propanoic acid …
Matched Description: … Tiaprofenic acid is a non-steroidal anti-inflammatory drug employed in the treatment of pain, particularly ... It belongs to the _arylpropionic acid_ (profen) group of nonsteroidal anti-inflammatory drugs (NSAIDs …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Acids, Acyclic ... Fatty Acids ... Carboxylic Acids …
Matched Products: … Teva-tiaprofenic Acid …
Rumex crispus top
Rumex crispus top allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Rumex crispus flower/leaf/stem extract …
Dihomo-gamma-linolenic acid
A 20-carbon-chain fatty acid, unsaturated at positions 8, 11, and 14. It differs from arachidonic acid, 5,8,11,14-eicosatetraenoic acid, only at position 5.
Investigational
Nutraceutical
Matched International brands: … Tona-lean 1000 CLA …
Matched Synonyms: … (8Z,11Z,14Z)-Icosatrienoic acid ... dihomo-γ-linolenic acid ... 8,11,14-Eicosatrienoic Acid …
Matched Name: … Dihomo-gamma-linolenic acid …
Matched Iupac: … (8Z,11Z,14Z)-icosa-8,11,14-trienoic acid …
Matched Description: … A 20-carbon-chain fatty acid, unsaturated at positions 8, 11, and 14. ... It differs from arachidonic acid, 5,8,11,14-eicosatetraenoic acid, only at position 5. …
Matched Categories: … Fatty Acids ... Fatty Acids, Unsaturated …
Matched Synonyms: … (8Z,11Z,14Z)-Icosatrienoic acid ... dihomo-γ-linolenic acid ... 8,11,14-Eicosatrienoic Acid …
Matched Name: … Dihomo-gamma-linolenic acid …
Matched Iupac: … (8Z,11Z,14Z)-icosa-8,11,14-trienoic acid …
Matched Description: … A 20-carbon-chain fatty acid, unsaturated at positions 8, 11, and 14. ... It differs from arachidonic acid, 5,8,11,14-eicosatetraenoic acid, only at position 5. …
Matched Categories: … Fatty Acids ... Fatty Acids, Unsaturated …
Hypochlorite
Hypochlorite is an ion composed of chlorine and oxygen with the chemical formula ClO−. Being unstable in the pure form, hypochlorite is most commonly used for bleaching, disinfectation, and water treatment purposes in its salt form, sodium hypochlorite. Hypochlorite is often used as a chemical reagent for chlorination and oxidation...
Approved
Matched Description: … Hypochlorite is an ion composed of chlorine and oxygen with the chemical formula ClO−. ... Being unstable in the pure form, hypochlorite is most commonly used for bleaching, disinfectation, and ... Hypochlorite is often used as a chemical reagent for chlorination and oxidation reactions. …
Matched Categories: … Antiseptics and Disinfectants ... Chlorine Compounds ... Acids ... Acids, Noncarboxylic …
Matched Products: … SUPERCLEAN Micro Acid Hypochlorite Disinfectant …
Matched Categories: … Antiseptics and Disinfectants ... Chlorine Compounds ... Acids ... Acids, Noncarboxylic …
Matched Products: … SUPERCLEAN Micro Acid Hypochlorite Disinfectant …
L-Dilinoleoyllecithin
Experimental
Matched Synonyms: … 1,2-dilinoleoyl-sn-glycero-3-phosphocholine ... 1,2-di-O-linoleoyl-sn-glycero-3-phosphocholine ... 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine …
Matched Categories: … Phosphatidic Acids …
Matched Categories: … Phosphatidic Acids …
Amoxicillin
Amoxicillin, or BRL-2333, is a penicillin G derivative first described in the literature in 1972. Amoxicillin has similar activity to penicillin and ampicillin, but leads to higher serum concentrations than ampicillin. Amoxicillin was granted FDA approval on 18 January 1974.
Approved
Vet approved
Matched Synonyms: … Amoxicillin anhydrous ... Amoxicillin (anhydrous) ... 6-(p-hydroxy-α-aminophenylacetamido)penicillanic acid …
Matched Iupac: … amino-2-(4-hydroxyphenyl)acetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Description: … [A190648] Amoxicillin has similar activity to [penicillin] and [ampicillin], but leads to higher serum …
Matched Mixtures name: … ACIX® ... Amoxicillin and clavulanate potassium ... Amoxicillin and clavulanate potassium …
Matched Categories: … Drugs for Acid Related Disorders ... Alimentary Tract and Metabolism ... vonoprazan and amoxicillin ... rabeprazole, amoxicillin and clarithromycin ... vonoprazan, amoxicillin and clarithromycin …
Matched Products: … AMOXICILLINA E ACIDO CLAVULANICO PFIZER …
Matched Iupac: … amino-2-(4-hydroxyphenyl)acetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Description: … [A190648] Amoxicillin has similar activity to [penicillin] and [ampicillin], but leads to higher serum …
Matched Mixtures name: … ACIX® ... Amoxicillin and clavulanate potassium ... Amoxicillin and clavulanate potassium …
Matched Categories: … Drugs for Acid Related Disorders ... Alimentary Tract and Metabolism ... vonoprazan and amoxicillin ... rabeprazole, amoxicillin and clarithromycin ... vonoprazan, amoxicillin and clarithromycin …
Matched Products: … AMOXICILLINA E ACIDO CLAVULANICO PFIZER …
Maltose
A dextrodisaccharide from malt and starch. It is used as a sweetening agent and fermentable intermediate in brewing (Grant & Hackh's Chemical Dictionary, 5th ed).
Experimental
Investigational
Matched Synonyms: … Maltose anhydrous …
Matched Description: … A dextrodisaccharide from malt and starch. ... It is used as a sweetening agent and fermentable intermediate in brewing (Grant & Hackh's Chemical …
Matched Categories: … Diet, Food, and Nutrition …
Matched Description: … A dextrodisaccharide from malt and starch. ... It is used as a sweetening agent and fermentable intermediate in brewing (Grant & Hackh's Chemical …
Matched Categories: … Diet, Food, and Nutrition …
Gadodiamide
Gadodiamide is a linear, non-ionic gadolinium-based contrast agent (GBCA) that is used in magnetic resonance imaging (MRI) procedures to assist in the visualization of blood vessels.[A263086,A263091] GBCAs constitute the largest group of MR agents, and they are thought to be safer than nonionic iodinated contrast agents. Approved by the FDA...
Approved
Investigational
Matched Synonyms: … Gadodiamide anhydrous …
Matched Description: … [A263086,A263091] GBCAs constitute the largest group of MR agents, and they are thought to be safer than ... to more gadolinium retention in the brain and thus more likely to cause side effects. ... since linear, non-ionic GBCA is less stable than macrocyclic or ionic GBCA, gadodiamide can potentially lead …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
Matched Description: … [A263086,A263091] GBCAs constitute the largest group of MR agents, and they are thought to be safer than ... to more gadolinium retention in the brain and thus more likely to cause side effects. ... since linear, non-ionic GBCA is less stable than macrocyclic or ionic GBCA, gadodiamide can potentially lead …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
Argatroban
Argatroban is a direct, selective thrombin inhibitor. The American College of Cardiologists (ACC) recommend using bivalirudin or argatroban in patients who have had, or at risk for, heparin induced thrombocytopenia (HIT) and are undergoing percutaneous coronary intervention. Argatroban is a non-heparin anticoagulant shown to both normalize platelet count in patients...
Approved
Investigational
Matched Synonyms: … Argatroban anhydrous …
Matched Iupac: … carbamimidamido-2-(3-methyl-1,2,3,4-tetrahydroquinoline-8-sulfonamido)pentanoyl]-4-methylpiperidine-2-carboxylic acid …
Matched Description: … bivalirudin or argatroban in patients who have had, or at risk for, heparin induced thrombocytopenia (HIT) and ... Argatroban is a non-heparin anticoagulant shown to both normalize platelet count in patients with HIT and ... Parental anticoagulants must be stopped and a baseline activated partial thromboplastin time must be …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Amino Acids ... Acids, Heterocyclic ... Amino Acids, Basic …
Matched Iupac: … carbamimidamido-2-(3-methyl-1,2,3,4-tetrahydroquinoline-8-sulfonamido)pentanoyl]-4-methylpiperidine-2-carboxylic acid …
Matched Description: … bivalirudin or argatroban in patients who have had, or at risk for, heparin induced thrombocytopenia (HIT) and ... Argatroban is a non-heparin anticoagulant shown to both normalize platelet count in patients with HIT and ... Parental anticoagulants must be stopped and a baseline activated partial thromboplastin time must be …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Amino Acids ... Acids, Heterocyclic ... Amino Acids, Basic …
Regadenoson
Regadenoson is an A2A adenosine receptor agonist that causes coronary vasodilation and used for myocardial perfusion imagining. Manufactured by Astellas and FDA approved April 10, 2008.
Approved
Investigational
Matched Synonyms: … Regadenoson anhydrous …
Matched Description: … Manufactured by Astellas and FDA approved April 10, 2008. ... Regadenoson is an A2A adenosine receptor agonist that causes coronary vasodilation and used for myocardial …
Matched Description: … Manufactured by Astellas and FDA approved April 10, 2008. ... Regadenoson is an A2A adenosine receptor agonist that causes coronary vasodilation and used for myocardial …
Enalaprilat
Enalaprilat is the active metabolite of the orally available pro-drug, enalapril. Used in the treatment of hypertension, enalapril is an ACE inhibitor that prevents Angiotensin Converting Enzyme (ACE) from transforming angiotensin I into angiotensin II. As angiotensin II is responsible for vasoconstriction and sodium reabsorption in the proximal tubule of...
Approved
Matched Synonyms: … Enalaprilat anhydrous …
Matched Iupac: … (2S)-1-[(2S)-2-{[(1S)-1-carboxy-3-phenylpropyl]amino}propanoyl]pyrrolidine-2-carboxylic acid …
Matched Description: … As angiotensin II is responsible for vasoconstriction and sodium reabsorption in the proximal tubule ... of the kidney, down-regulation of this protein results in reduced blood pressure and blood fluid volume ... to overcome the limitations of the first ACE inhibitor, captopril, which had numerous side effects and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Iupac: … (2S)-1-[(2S)-2-{[(1S)-1-carboxy-3-phenylpropyl]amino}propanoyl]pyrrolidine-2-carboxylic acid …
Matched Description: … As angiotensin II is responsible for vasoconstriction and sodium reabsorption in the proximal tubule ... of the kidney, down-regulation of this protein results in reduced blood pressure and blood fluid volume ... to overcome the limitations of the first ACE inhibitor, captopril, which had numerous side effects and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Tofogliflozin
Tofogliflozin has been used in trials studying the treatment and prevention of Diabetes Mellitus Type 2.
Investigational
Matched Synonyms: … Tofogliflozin anhydrous …
Matched Description: … Tofogliflozin has been used in trials studying the treatment and prevention of Diabetes Mellitus Type …
Matched Description: … Tofogliflozin has been used in trials studying the treatment and prevention of Diabetes Mellitus Type …
Relebactam
Relebactam is a diazabicyclooctane beta-lactamase inhibitor, similar in structure to avibactam.[A181195,A181207] It includes a piperidine ring which reduces export from bacterial cells by producing a positive charge. It is currently available in a combination product which includes imipenem and cilastatin to treat complicated urinary tract infections (UTIs), pyelonephritis, and complicated...
Approved
Investigational
Matched Synonyms: … Relebactam anhydrous …
Matched Iupac: … [(1R,2S,5R)-7-oxo-2-[(piperidin-4-yl)carbamoyl]-1,6-diazabicyclo[3.2.1]octan-6-yl]oxidanesulfonic acid …
Matched Description: … [A181207] It is currently available in a combination product which includes [imipenem] and [cilastatin ... ] to treat complicated urinary tract infections (UTIs), pyelonephritis, and complicated intra-abdominal ... [label] It is considered to be a last-line treatment option and gained FDA approval as part of the combination …
Matched Categories: … imipenem, cilastatin and relebactam …
Matched Iupac: … [(1R,2S,5R)-7-oxo-2-[(piperidin-4-yl)carbamoyl]-1,6-diazabicyclo[3.2.1]octan-6-yl]oxidanesulfonic acid …
Matched Description: … [A181207] It is currently available in a combination product which includes [imipenem] and [cilastatin ... ] to treat complicated urinary tract infections (UTIs), pyelonephritis, and complicated intra-abdominal ... [label] It is considered to be a last-line treatment option and gained FDA approval as part of the combination …
Matched Categories: … imipenem, cilastatin and relebactam …
Hydroxocobalamin
Hydroxocobalamin, also known as vitamin B12a and hydroxycobalamin, is an injectable form of vitamin B 12 that has been used therapeutically to treat vitamin B 12 deficiency. It is also used in cyanide poisoning, Leber's optic atrophy, and toxic amblyopia.
Approved
Matched Synonyms: … Hydroxocobalamin anhydrous ... Hydroxocobalaminum anhydrous …
Matched Description: … Hydroxocobalamin, also known as vitamin B12a and hydroxycobalamin, is an injectable form of vitamin B ... It is also used in cyanide poisoning, Leber's optic atrophy, and toxic amblyopia. …
Matched Categories: … Vitamin B12 and Folic Acid ... Blood and Blood Forming Organs …
Matched Description: … Hydroxocobalamin, also known as vitamin B12a and hydroxycobalamin, is an injectable form of vitamin B ... It is also used in cyanide poisoning, Leber's optic atrophy, and toxic amblyopia. …
Matched Categories: … Vitamin B12 and Folic Acid ... Blood and Blood Forming Organs …
Citrus sinensis pollen
Citrus sinensis pollen is the pollen of the Citrus sinensis plant. Citrus sinensis pollen is mainly used in allergenic testing.
Approved
Matched Name: … Citrus sinensis pollen …
Matched Description: … Citrus sinensis pollen is the pollen of the Citrus sinensis plant. ... Citrus sinensis pollen is mainly used in allergenic testing. …
Matched Description: … Citrus sinensis pollen is the pollen of the Citrus sinensis plant. ... Citrus sinensis pollen is mainly used in allergenic testing. …
Citrus aurantium fruit
Experimental
Matched Synonyms: … Citrus aurantium fruit extract …
Matched Name: … Citrus aurantium fruit …
Matched Name: … Citrus aurantium fruit …
Pentetic acid
Pentetic acid, also known as diethylenetriaminepentaacetic acid (DTPA), is a synthetic polyamino carboxylic acid with eight coordinate bond forming sites that can sequester metal ions and form highly stable DTPA-metal ion complexes. DTPA, along with its calcium and zinc trisodium salts, are the only FDA approved agents for the treatment...
Approved
Matched Synonyms: … Pentetic acid ... Diethylene triamine pentaacetic acid ... Diethylenetriamine pentaacetic acid …
Matched Name: … Pentetic acid …
Matched Iupac: … 2-[bis({2-[bis(carboxymethyl)amino]ethyl})amino]acetic acid …
Matched Description: … DTPA, along with its calcium and zinc trisodium salts, are the only FDA approved agents for the treatment ... acid with eight coordinate bond forming sites that can sequester metal ions and form highly stable DTPA-metal ... [L2242] DPTA was developed by the pharmaceutical company CIS US and FDA approved on April 14, 2004. …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Lead Chelator ... Lead Chelating Activity …
Matched Products: … Pentetic Acid …
Matched Name: … Pentetic acid …
Matched Iupac: … 2-[bis({2-[bis(carboxymethyl)amino]ethyl})amino]acetic acid …
Matched Description: … DTPA, along with its calcium and zinc trisodium salts, are the only FDA approved agents for the treatment ... acid with eight coordinate bond forming sites that can sequester metal ions and form highly stable DTPA-metal ... [L2242] DPTA was developed by the pharmaceutical company CIS US and FDA approved on April 14, 2004. …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Lead Chelator ... Lead Chelating Activity …
Matched Products: … Pentetic Acid …
Displaying drugs 676 - 700 of 2683 in total