Displaying drugs 676 - 700 of 2337 in total
Urolithin A
Urolithin A is a metabolite of ellagic acid. It has been demonstrated to stimulate mitophagy and improve muscle health in old animals and in preclinical models of aging.
Investigational
Matched Synonyms: … 3,8-Hydroxydibenzo-alpha-pyrone …
Matched Description: … It has been demonstrated to stimulate mitophagy and improve muscle health in old animals and in preclinical …
Matched Description: … It has been demonstrated to stimulate mitophagy and improve muscle health in old animals and in preclinical …
Tridecactide
Tridecactide, also known as alpha-corticotropin 1-13, is a deacetylated and deaminated alpha-melanocyte stimulating hormone, which may have antipyretic, anti-inflammatory, and antimicrobial effects. Tridecactide, along with metenkefalin, are under investigation as an immunomodulatory therapy for moderate to severe COVID-19.[L13874,L13877]
Investigational
Matched Synonyms: … alpha-1-13-corticotropin, human …
Matched Iupac: … amino-1-[(2S)-2-{[(1S)-1-carboxy-2-methylpropyl]carbamoyl}pyrrolidin-1-yl]-1-oxohexan-2-yl]carbamoyl}methyl …
Matched Description: … Tridecactide, also known as alpha-corticotropin 1-13, is a deacetylated and deaminated alpha-melanocyte ... stimulating hormone, which may have antipyretic, anti-inflammatory, and antimicrobial effects. …
Matched Iupac: … amino-1-[(2S)-2-{[(1S)-1-carboxy-2-methylpropyl]carbamoyl}pyrrolidin-1-yl]-1-oxohexan-2-yl]carbamoyl}methyl …
Matched Description: … Tridecactide, also known as alpha-corticotropin 1-13, is a deacetylated and deaminated alpha-melanocyte ... stimulating hormone, which may have antipyretic, anti-inflammatory, and antimicrobial effects. …
Disufenton
Investigational
Matched Synonyms: … 2,4-disulfonyl-.alpha.-phenyl-tert-butylnitrone ... 1,3-benzenedisulfonic acid, 4-(((1,1-dimethylethyl)oxidoimino)methyl)- ... 4-(((1,1-dimethylethyl)imino)methyl)benzene-1,3-disulfonate n-oxide …
Metanitrophenyl-Alpha-D-Galactoside
Experimental
Matched Name: … Metanitrophenyl-Alpha-D-Galactoside …
alpha-D-galacturonic acid
The α-anomer of D-galacturonic acid.
Experimental
Matched Synonyms: … alpha-D-galactopyranuronic acid …
Matched Name: … alpha-D-galacturonic acid …
Matched Name: … alpha-D-galacturonic acid …
Fluoroestradiol F-18
Fluoroestradiol F-18 is an imaging agent used with positron emission tomography (PET) to detect estrogen receptor-positive breast cancer lesions. The ability to image ER-positive tumors in vivo is advantageous in that, while helping to visualize tumor progression/regression, it may also be used to assess for heterogeneity in ER expression across...
Approved
Matched Synonyms: … F-18 16 alpha-Fluoroestradiol ... 16-alpha-(18-Fluoro)-17betaestradiol ... 16-alpha-(18F)Fluoro-17beta-estradiol …
Matched Iupac: … (1R,2R,3aS,3bR,9bS,11aS)-2-(¹⁸F)fluoro-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[ …
Matched Description: … PETNET Solutions, Inc. and Zionexa USA under the brand name Cerianna. ... [A203912] Fluoroestradiol F-18 was first granted FDA approval in May 2020, and will be developed by …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Iupac: … (1R,2R,3aS,3bR,9bS,11aS)-2-(¹⁸F)fluoro-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[ …
Matched Description: … PETNET Solutions, Inc. and Zionexa USA under the brand name Cerianna. ... [A203912] Fluoroestradiol F-18 was first granted FDA approval in May 2020, and will be developed by …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Bromocriptine
Bromocriptine mesylate is a semisynthetic ergot alkaloid derivative with potent dopaminergic activity. It inhibits prolactin secretion and may be used to treat dysfunctions associated with hyperprolactinemia. Bromocriptine is also indicated for the management of signs and symptoms of Parkinsonian Syndrome, as well as the treatment of acromegaly. Bromocriptine has been...
Approved
Investigational
Withdrawn
Matched Synonyms: … 2-Bromo-alpha-ergocryptine ... 2-Bromo-alpha-ergokryptin ... 2-Bromo-alpha-ergokryptine …
Matched Iupac: … -7-(2-methylpropyl)-5,8-dioxo-4-(propan-2-yl)-3-oxa-6,9-diazatricyclo[7.3.0.0^{2,6}]dodecan-4-yl]-6-methyl …
Matched Description: … It inhibits prolactin secretion and may be used to treat dysfunctions associated with hyperprolactinemia ... Bromocriptine is also indicated for the management of signs and symptoms of Parkinsonian Syndrome, as ... Bromocriptine has been associated with pulmonary fibrosis, and can also cause sustained suppression of …
Matched Categories: … Ergot Alkaloids and Derivatives ... Genito Urinary System and Sex Hormones ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Adrenergic alpha-Agonists ... Adrenergic alpha-Antagonists …
Matched Iupac: … -7-(2-methylpropyl)-5,8-dioxo-4-(propan-2-yl)-3-oxa-6,9-diazatricyclo[7.3.0.0^{2,6}]dodecan-4-yl]-6-methyl …
Matched Description: … It inhibits prolactin secretion and may be used to treat dysfunctions associated with hyperprolactinemia ... Bromocriptine is also indicated for the management of signs and symptoms of Parkinsonian Syndrome, as ... Bromocriptine has been associated with pulmonary fibrosis, and can also cause sustained suppression of …
Matched Categories: … Ergot Alkaloids and Derivatives ... Genito Urinary System and Sex Hormones ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Adrenergic alpha-Agonists ... Adrenergic alpha-Antagonists …
UDP-alpha-D-xylose
The decarboxylation product of UDPglucuronic acid, which is used for formation of the xylosides of seryl hydroxyl groups in mucoprotein synthesis. Also forms plant xylans.
Experimental
Matched Name: … UDP-alpha-D-xylose …
Alpha-Cyclodextrin (Cyclohexa-Amylose)
Experimental
Matched Name: … Alpha-Cyclodextrin (Cyclohexa-Amylose) …
Alpha-Methylene Adenosine Monophosphate
Experimental
Matched Name: … Alpha-Methylene Adenosine Monophosphate …
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(methyl)phosphinic acid …
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(methyl)phosphinic acid …
PHENYLAMINOIMIDAZO(1,2-ALPHA)PYRIDINE
Experimental
Matched Name: … PHENYLAMINOIMIDAZO(1,2-ALPHA)PYRIDINE …
Biperiden
A muscarinic antagonist that has effects in both the central and peripheral nervous systems. It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. It has also been used to alleviate extrapyramidal symptoms induced by phenothiazine derivatives and reserpine.
Approved
Investigational
Matched Synonyms: … alpha-5-norbornen-2-yl-alpha-phenyl-1-piperidinepropanol ... alpha-bicyclo[2.2.1]hept-5-en-2-yl-alpha-phenyl-1-piperidinepropanol …
Matched Description: … A muscarinic antagonist that has effects in both the central and peripheral nervous systems. ... It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. ... It has also been used to alleviate extrapyramidal symptoms induced by phenothiazine derivatives and reserpine …
Matched Description: … A muscarinic antagonist that has effects in both the central and peripheral nervous systems. ... It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. ... It has also been used to alleviate extrapyramidal symptoms induced by phenothiazine derivatives and reserpine …
Choriogonadotropin alfa
Recombinant human chorionic gonadotropin with 2 subunits, alpha = 92 residues, beta = 145 residues, each with N-and O-linked carbohydrate moieties linked to ASN-52 and ASN-78 (on alpha subunit) and ASN-13, ASN-30, SER-121, SER-127, SER-132 and SER-138 (on beta subunit). The primary structure of the alpha-chain of r-hCG is identical...
Approved
Matched Synonyms: … Choriogonadotropin alpha …
Matched Description: … with N-and O-linked carbohydrate moieties linked to ASN-52 and ASN-78 (on alpha subunit) and ASN-13, ... and LH. ... ASN-30, SER-121, SER-127, SER-132 and SER-138 (on beta subunit). …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gonadotropins and Antigonadotropins ... Sex Hormones and Modulators of the Genital System …
Matched Description: … with N-and O-linked carbohydrate moieties linked to ASN-52 and ASN-78 (on alpha subunit) and ASN-13, ... and LH. ... ASN-30, SER-121, SER-127, SER-132 and SER-138 (on beta subunit). …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gonadotropins and Antigonadotropins ... Sex Hormones and Modulators of the Genital System …
Interferon alfa-2b
Interferon alpha 2b (human leukocyte clone hif-sn 206 protein moiety reduced). A type I interferon consisting of 165 amino acid residues with arginine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent.
Approved
Matched Synonyms: … r-INF-alpha ... rIFN-alpha-2b ... Interferon alpha-2B …
Matched Description: … This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes ... Interferon alpha 2b (human leukocyte clone hif-sn 206 protein moiety reduced). …
Matched Mixtures name: … Rebetron Ready To Use Solution (albumin(human)free) (6000000 Iu/ml and 200mg Capsules) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins ... Interferon alpha ... Interferon-alpha …
Matched Description: … This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes ... Interferon alpha 2b (human leukocyte clone hif-sn 206 protein moiety reduced). …
Matched Mixtures name: … Rebetron Ready To Use Solution (albumin(human)free) (6000000 Iu/ml and 200mg Capsules) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins ... Interferon alpha ... Interferon-alpha …
NBI-98782
Approved
Investigational
Matched Synonyms: … (+)-.alpha.-dihydrotetrabenazine ... (+)-alpha-dihydrotetrabenazine ... Dihydrotetrabenazine, (+)-.alpha.- …
Benzatropine
Benztropine, with the chemical formula 3alpha-diphenylmethoxytropane, is a tropane-based dopamine inhibitor used for the symptomatic treatment of Parkinson's disease. It is a combination molecule between a tropane ring, similar to cocaine, and a diphenyl ether from the dialkylpiperazines determined to be a dopamine uptake inhibitor since 1970. The generation of...
Approved
Matched Synonyms: … 3-alpha-(diphenylmethoxy)tropane ... 3α-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane ... benzhydryl 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ether …
Matched Iupac: … (1R,3R,5S)-3-(diphenylmethoxy)-8-methyl-8-azabicyclo[3.2.1]octane …
Matched Description: … It is a combination molecule between a tropane ring, similar to cocaine, and a diphenyl ether from the ... [A37914] Benztropine was developed by USL Pharma and officially approved by the FDA on 1996.[L5500] ... an increased potency for dopamine uptake inhibition as well as a decreased inhibition of serotonin and …
Matched Iupac: … (1R,3R,5S)-3-(diphenylmethoxy)-8-methyl-8-azabicyclo[3.2.1]octane …
Matched Description: … It is a combination molecule between a tropane ring, similar to cocaine, and a diphenyl ether from the ... [A37914] Benztropine was developed by USL Pharma and officially approved by the FDA on 1996.[L5500] ... an increased potency for dopamine uptake inhibition as well as a decreased inhibition of serotonin and …
NB-124 sulfate
Investigational
Matched Synonyms: … 6'-(r)-methyl-5-o-(5-amino-5,6-dideoxy-alpha-l-talofuranosyl)-paromamine sulfate ... -d-allofuranosyl-(1->5)-o-(2-amino-2,7-dideoxy-d-glycero-.alpha. ... 6'-(r)-methyl-5-o-(5-amino-5,6-dideoxy-a-l-talofuranosyl)- paromamine sulfate …
Ethyl 8-hydroxy-alpha-(2-propynylamino)-5-quinolinepropanoate
Experimental
Matched Synonyms: … Ethyl 8-hydroxy-alpha-(2-propynylamino)-5-quinolinepropanoate ... 5-Quinolinepropanoic acid, 8-hydroxy-alpha-(2-propyn-1-ylamino)-, ethyl ester …
Matched Name: … Ethyl 8-hydroxy-alpha-(2-propynylamino)-5-quinolinepropanoate …
Matched Name: … Ethyl 8-hydroxy-alpha-(2-propynylamino)-5-quinolinepropanoate …
Promethazine
Promethazine, originally known as 3,277 R.P., is an N-dimethylaminopropyl derivative of phenothiazine that was developed in France in 1946. Promethazine antagonizes a variety of receptors, allowing it to be used for a number of indications including allergic reactions, pain, sedation, nausea, and vomiting.[A189907,A190153,A190159,A190150,A190171]
Promethazine was granted FDA approval before 29...
Approved
Investigational
Matched Synonyms: … N,N,alpha-trimethyl-10H-phenothiazine-10-ethanamine ... (2-dimethylamino-2-methyl)ethyl-N-dibenzoparathiazine ... N-(2'-dimethylamino-2'-methyl)ethylphenothiazine …
Matched Description: … allowing it to be used for a number of indications including allergic reactions, pain, sedation, nausea, and …
Matched Mixtures name: … Meperidine Hcl and Promethazine Hcl ... Promethazine Hydrochloride and Codeine Phosphate ... Promethazine Hydrochloride and Dextromethorphan Hydrobromide …
Matched Categories: … prednisolone and promethazine ... Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Description: … allowing it to be used for a number of indications including allergic reactions, pain, sedation, nausea, and …
Matched Mixtures name: … Meperidine Hcl and Promethazine Hcl ... Promethazine Hydrochloride and Codeine Phosphate ... Promethazine Hydrochloride and Dextromethorphan Hydrobromide …
Matched Categories: … prednisolone and promethazine ... Miscellaneous Anxiolytics Sedatives and Hypnotics …
Metformin
Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes.[L12207,A176173]
Metformin is considered an antihyperglycemic drug because it lowers blood glucose concentrations in type II diabetes without causing hypoglycemia. It is commonly described as an "insulin sensitizer", leading to a decrease in insulin...
Approved
Matched Description: … Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management ... It is commonly described as an "insulin sensitizer", leading to a decrease in insulin resistance and ... [A36559]
Metformin was first approved in Canada in 1972,[A36552] and received subsequent FDA approval …
Matched Mixtures name: … Glipizide and Metformin Hydrochloride ... Glipizide and Metformin Hydrochloride ... Glipizide and Metformin Hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and ertugliflozin ... metformin and gemigliptin ... metformin and linagliptin ... metformin and sulfonylureas …
Matched Products: … METVEL 850 MG FILM KAPLI TABLET, 50 FILM KAPLI TABLET ... METVEL 850 MG FILM KAPLI TABLET, 100 FILM KAPLI TABLET ... METVEL SR 1000 MG UZATILMIŞ SALIMLI TABLET , 56 TABLET …
Matched Mixtures name: … Glipizide and Metformin Hydrochloride ... Glipizide and Metformin Hydrochloride ... Glipizide and Metformin Hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and ertugliflozin ... metformin and gemigliptin ... metformin and linagliptin ... metformin and sulfonylureas …
Matched Products: … METVEL 850 MG FILM KAPLI TABLET, 50 FILM KAPLI TABLET ... METVEL 850 MG FILM KAPLI TABLET, 100 FILM KAPLI TABLET ... METVEL SR 1000 MG UZATILMIŞ SALIMLI TABLET , 56 TABLET …
Displaying drugs 676 - 700 of 2337 in total