This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Disufenton
- DrugBank Accession Number
- DB17298
- Background
Not Available
- Type
- Small Molecule
- Groups
- Investigational
- Structure
Structure for Disufenton (DB17298)
- Weight
- Average: 337.36
Monoisotopic: 337.028994175 - Chemical Formula
- C11H15NO7S2
- Synonyms
- 1,3-benzenedisulfonic acid, 4-(((1,1-dimethylethyl)oxidoimino)methyl)-
- 2,4-disulfonyl-.alpha.-phenyl-tert-butylnitrone
- 4-(((1,1-dimethylethyl)imino)methyl)benzene-1,3-disulfonate n-oxide
- 4-(((1,1-dimethylethyl)imino)methyl)benzene-1,3-disulphonate n-oxide
- 4-(((1,1-dimethylethyl)oxidoimino)methyl)-1,3-benzenedisulfonic acid
- 4-tert-butyliminomethyl)benzene-,3-disulfonate n-oxide
- 4-tert-butyliminomethyl)benzene-,3-disulphonate n-oxide
Pharmacology
- Indication
Not Available
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Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Product Ingredients
Ingredient UNII CAS InChI Key Disufenton sodium 7M1J3HN9VO 168021-79-2 XLZOVRYBVCMCGL-UHFFFAOYSA-L
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 797K01YF1M
- CAS number
- 168021-77-0
- InChI Key
- OVTCHWSLKGENKP-GHXNOFRVSA-N
- InChI
- InChI=1S/C11H15NO7S2/c1-11(2,3)12(13)7-8-4-5-9(20(14,15)16)6-10(8)21(17,18)19/h4-7H,1-3H3,(H,14,15,16)(H,17,18,19)/b12-7-
- IUPAC Name
- (Z)-tert-butyl[(2,4-disulfophenyl)methylidene]oxidoazanium
- SMILES
- CC(C)(C)[N+](\[O-])=C\C1=C(C=C(C=C1)S(O)(=O)=O)S(O)(=O)=O
References
- General References
- Not Available
- External Links
- ChemSpider
- 5289390
- ChEMBL
- CHEMBL1206050
- ZINC
- ZINC000002022427
- Wikipedia
- Disufenton_sodium
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 3 Completed Treatment Stroke / Stroke, Acute / Stroke, Cerebrovascular / Transient Ischemic Attack 1 3 Completed Treatment Stroke / Transient Ischemic Attack 1 2 Active Not Recruiting Treatment Glioblastoma Multiforme (GBM) of the Brain / Recurrent Malignant Gliomas 1 2 Completed Treatment Cerebral Hemorrhage 1 1 Active Not Recruiting Treatment Recurrent Malignant Gliomas 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.398 mg/mL ALOGPS logP -2.1 ALOGPS logP -2.1 Chemaxon logS -2.9 ALOGPS pKa (Strongest Acidic) -2.9 Chemaxon Physiological Charge -2 Chemaxon Hydrogen Acceptor Count 7 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 134.81 Å2 Chemaxon Rotatable Bond Count 4 Chemaxon Refractivity 78.1 m3·mol-1 Chemaxon Polarizability 31.55 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
Spectrum Spectrum Type Splash Key Predicted 1H NMR Spectrum 1D NMR Not Applicable Predicted 13C NMR Spectrum 1D NMR Not Applicable - Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at December 02, 2022 20:35 / Updated at September 28, 2023 05:47