Displaying drugs 676 - 700 of 1895 in total
Thenalidine
Withdrawn from the Canadian, US, and UK markets in 1963 due to concerns involving neutropenia.
Approved
Withdrawn
Matched Synonyms: … 1-Methyl-4-N-2-thenylanilinopiperidine ... 1-Methyl-4-amino-N-phenyl-N-(2-thenyl)piperidine …
Matched Iupac: … 1-methyl-N-phenyl-N-[(thiophen-2-yl)methyl]piperidin-4-amine …
Matched Description: … Withdrawn from the Canadian, US, and UK markets in 1963 due to concerns involving neutropenia. …
Matched Iupac: … 1-methyl-N-phenyl-N-[(thiophen-2-yl)methyl]piperidin-4-amine …
Matched Description: … Withdrawn from the Canadian, US, and UK markets in 1963 due to concerns involving neutropenia. …
Flubendazole
Flubendazole is an anthelmintic that is used to treat worm infection in humans. It is available OTC in Europe.
Experimental
Withdrawn
Matched Synonyms: … methyl 5-(p-fluorobenzoyl)-2-benzimidazolecarbamate ... (5-(4-fluorobenzoyl)-1H-benzimidazole-2-yl)carbamic acid methyl ester …
Matched Iupac: … methyl N-[5-(4-fluorobenzoyl)-1H-1,3-benzodiazol-2-yl]carbamate …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …
Matched Iupac: … methyl N-[5-(4-fluorobenzoyl)-1H-1,3-benzodiazol-2-yl]carbamate …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …
Defactinib
Defactinib has been investigated for the treatment of Malignant Pleural Mesothelioma.
Investigational
Matched Synonyms: … N-methyl-4-[[4-[[3-[methyl(methylsulfonyl)amino]pyrazin-2-yl]methylamino]-5-(trifluoromethyl)pyrimidin …
Matched Iupac: … N-methyl-4-{[4-({[3-(N-methylmethanesulfonamido)pyrazin-2-yl]methyl}amino)-5-(trifluoromethyl)pyrimidin …
Matched Iupac: … N-methyl-4-{[4-({[3-(N-methylmethanesulfonamido)pyrazin-2-yl]methyl}amino)-5-(trifluoromethyl)pyrimidin …
Secnidazole
Secnidazole is a second-generation 5-nitroimidazole antimicrobial agent. It is structurally related to other 5-nitroimidazoles, including DB00916 and DB00911, but displays improved oral absorption and a longer terminal elimination half-life than other drugs in this class. Secnidazole is selective against many anaerobic Gram-positive and Gram-negative bacteria as well as protozoa. Once...
Approved
Matched Synonyms: … 1-(2 hydroxypropyl)-2-methyl-5-nitroimidazole ... 1-(2-methyl-5-nitro-1H-imidazol-1-yl) propan-2 ol …
Matched Iupac: … 1-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-ol …
Matched Description: … to form a radical anion, thereby damaging and killing the target pathogen. ... It is structurally related to other 5-nitroimidazoles, including [DB00916] and [DB00911], but displays ... improved oral absorption and a longer terminal elimination half-life than other drugs in this class. …
Matched Categories: … azithromycin, fluconazole and secnidazole ... Antiparasitic Products, Insecticides and Repellents …
Matched Iupac: … 1-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-ol …
Matched Description: … to form a radical anion, thereby damaging and killing the target pathogen. ... It is structurally related to other 5-nitroimidazoles, including [DB00916] and [DB00911], but displays ... improved oral absorption and a longer terminal elimination half-life than other drugs in this class. …
Matched Categories: … azithromycin, fluconazole and secnidazole ... Antiparasitic Products, Insecticides and Repellents …
Alogabat
Investigational
Matched Synonyms: … 3-pyridazinecarboxamide, 6-((5-methyl-3-(6-methyl-3-pyridinyl)-4-isoxazolyl)methoxy)-n-(tetrahydro-2h-pyran …
Matched Iupac: … 6-{[5-methyl-3-(6-methylpyridin-3-yl)-1,2-oxazol-4-yl]methoxy}-N-(oxan-4-yl)pyridazine-3-carboxamide …
Matched Iupac: … 6-{[5-methyl-3-(6-methylpyridin-3-yl)-1,2-oxazol-4-yl]methoxy}-N-(oxan-4-yl)pyridazine-3-carboxamide …
3-(6-Aminopyridin-3-Yl)-N-Methyl-N-[(1-Methyl-1h-Indol-2-Yl)Methyl]Acrylamide
Experimental
Matched Name: … 3-(6-Aminopyridin-3-Yl)-N-Methyl-N-[(1-Methyl-1h-Indol-2-Yl)Methyl]Acrylamide …
Matched Iupac: … (2E)-3-(6-aminopyridin-3-yl)-N-methyl-N-[(1-methyl-1H-indol-2-yl)methyl]prop-2-enamide …
Matched Iupac: … (2E)-3-(6-aminopyridin-3-yl)-N-methyl-N-[(1-methyl-1H-indol-2-yl)methyl]prop-2-enamide …
2'-O-Methyl-3'-Methyl-3'-Deoxy-Arabinofuranosyl-Thymine-5'-Phosphate
Experimental
Matched Name: … 2'-O-Methyl-3'-Methyl-3'-Deoxy-Arabinofuranosyl-Thymine-5'-Phosphate …
Matched Iupac: … {[(2S,3R,4R,5R)-4-methoxy-3-methyl-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl …
Matched Iupac: … {[(2S,3R,4R,5R)-4-methoxy-3-methyl-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl …
Encainide
All drug products containing encainide hydrochloride. Encainide hydrochloride, formerly marketed as Enkaid capsules, was associated with increased death rates in patients who had asymptomatic heart rhythm abnormalities after a recent heart attack. The manufacturer of Enkaid capsules voluntarily withdrew the product from the US market on December 16, 1991.
Approved
Investigational
Withdrawn
Matched Synonyms: … (±)-2'-[2-(1-methyl-2-piperidyl)ethyl]-p-anisanilide ... 4-methoxy-2'-[2-(1-methyl-2-piperidyl)ethyl]benzanilide ... (±)-4-methoxy-N-(2-(2-(1-methyl-2-piperidinyl)ethyl)phenyl)benzamide …
N(4)-Adenosyl-N(4)-methyl-2,4-diaminobutanoic acid
N(4)-adenosyl-n(4)-methyl-2,4-diaminobutanoic acid is a solid. This compound belongs to the purine nucleosides and analogues. These are compounds comprising a purine base attached to a sugar.
Experimental
Matched Synonyms: … 5'-{[(3S)-3-Amino-3-carboxypropyl](methyl)amino}-5'-deoxyadenosine …
Matched Name: … N(4)-Adenosyl-N(4)-methyl-2,4-diaminobutanoic acid …
Matched Iupac: … (2S)-2-amino-4-({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl}(methyl)amino …
Matched Description: … This compound belongs to the purine nucleosides and analogues. ... N(4)-adenosyl-n(4)-methyl-2,4-diaminobutanoic acid is a solid. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Name: … N(4)-Adenosyl-N(4)-methyl-2,4-diaminobutanoic acid …
Matched Iupac: … (2S)-2-amino-4-({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl}(methyl)amino …
Matched Description: … This compound belongs to the purine nucleosides and analogues. ... N(4)-adenosyl-n(4)-methyl-2,4-diaminobutanoic acid is a solid. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Monomethyl fumarate
Approved
Experimental
Investigational
Matched Synonyms: … Methyl hydrogen fumarate …
Topotecan
An antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA topoisomerases, type I.
Approved
Investigational
Matched Synonyms: … 9-[(dimethylamino)methyl]-10-hydroxy-(4S)-camptothecin …
Matched Iupac: … (19S)-8-[(dimethylamino)methyl]-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0^{2,11}.0 …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … (19S)-8-[(dimethylamino)methyl]-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0^{2,11}.0 …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Levofloxacin
Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic ofloxacin. It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive bacteria compared to R-(+)-ofloxacin and remains stereochemically stable following administration (i.e. it does not invert to the inactive isomer). Levofloxacin, along with other quinolones...
Approved
Investigational
Matched Synonyms: … (3S)-(-)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine ... (S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine ... (S)-(-)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzooxazine …
Matched Iupac: … (2S)-7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5 …
Matched Description: … [A31453,A190756] Levofloxacin was first approved by the FDA in 1996, and was approved in Canada and ... Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic [ofloxacin]. ... [A190663] It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive …
Matched Categories: … Alimentary Tract and Metabolism ... levofloxacin and ornidazole ... lansoprazole, amoxicillin and levofloxacin ... Metabolic Side Effects of Drugs and Substances …
Matched Iupac: … (2S)-7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5 …
Matched Description: … [A31453,A190756] Levofloxacin was first approved by the FDA in 1996, and was approved in Canada and ... Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic [ofloxacin]. ... [A190663] It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive …
Matched Categories: … Alimentary Tract and Metabolism ... levofloxacin and ornidazole ... lansoprazole, amoxicillin and levofloxacin ... Metabolic Side Effects of Drugs and Substances …
2-Allyl-6-Methyl-Phenol
Experimental
Matched Name: … 2-Allyl-6-Methyl-Phenol …
Matched Iupac: … 2-methyl-6-(prop-2-en-1-yl)phenol …
Matched Iupac: … 2-methyl-6-(prop-2-en-1-yl)phenol …
3-methyl-benzene-1,2-diol
3-methyl-benzene-1,2-diol is a solid. This compound belongs to the catechols. These are compounds containing a 1,2-benzenediol moeity. 3-methyl-benzene-1,2-diol targets the protein biphenyl-2,3-diol 1,2-dioxygenase.
Experimental
Matched Name: … 3-methyl-benzene-1,2-diol …
Matched Description: … 3-methyl-benzene-1,2-diol is a solid. This compound belongs to the catechols. ... These are compounds containing a 1,2-benzenediol moeity. 3-methyl-benzene-1,2-diol targets the protein …
Matched Description: … 3-methyl-benzene-1,2-diol is a solid. This compound belongs to the catechols. ... These are compounds containing a 1,2-benzenediol moeity. 3-methyl-benzene-1,2-diol targets the protein …
7-methyl-5'-guanylic acid
Experimental
Matched Name: … 7-methyl-5'-guanylic acid …
Matched Iupac: … 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl]-7-methyl-6-oxo-6,9-dihydro …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Iupac: … 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl]-7-methyl-6-oxo-6,9-dihydro …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
2-Chloro-6-Methyl-Aniline
Experimental
Matched Name: … 2-Chloro-6-Methyl-Aniline …
Matched Iupac: … (1S)-2-methyl-6-methylidenecyclohexa-2,4-dien-1-amine …
Matched Iupac: … (1S)-2-methyl-6-methylidenecyclohexa-2,4-dien-1-amine …
Ethyl-Carbamic Acid Methyl Ester
Experimental
Matched Name: … Ethyl-Carbamic Acid Methyl Ester …
Matched Iupac: … methyl N-ethylcarbamate …
Matched Iupac: … methyl N-ethylcarbamate …
Ivaltinostat
Investigational
Matched Synonyms: … (E)-N-(3-(DIMETHYLAMINO)PROPYL)-N'-HYDROXY-2-((1-NAPHTHYLOXY)METHYL)-2-OCTENEDIAMIDE ... 2-OCTENEDIAMIDE, N1-(3-(DIMETHYLAMINO)PROPYL)-N8-HYDROXY-2-((1-NAPHTHALENYLOXY)METHYL)-, (2E)- …
Matched Iupac: … (2E)-N-[3-(dimethylamino)propyl]-N'-hydroxy-2-[(naphthalen-1-yloxy)methyl]oct-2-enediamide; phosphoric …
Matched Iupac: … (2E)-N-[3-(dimethylamino)propyl]-N'-hydroxy-2-[(naphthalen-1-yloxy)methyl]oct-2-enediamide; phosphoric …
Golcadomide
Investigational
Matched Synonyms: … 2-[(3S)-2,6-dioxopiperidin-3-yl]-4-{[(2-fluoro-4-{[3-(morpholin-4-yl)azetidin-1-yl]methyl} phenyl) methyl …
Matched Iupac: … 2-[(3S)-2,6-dioxopiperidin-3-yl]-4-{[(2-fluoro-4-{[3-(morpholin-4-yl)azetidin-1-yl]methyl}phenyl)methyl …
Matched Iupac: … 2-[(3S)-2,6-dioxopiperidin-3-yl]-4-{[(2-fluoro-4-{[3-(morpholin-4-yl)azetidin-1-yl]methyl}phenyl)methyl …
Trifluoperazine
A phenothiazine with actions similar to chlorpromazine. It is used as an antipsychotic and an antiemetic.
Approved
Investigational
Matched Synonyms: … trifluoromethyl-10-(3'-(1-methyl-4-piperazinyl)propyl)phenothiazine ... 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-10H-phenothiazine …
Matched Description: … It is used as an antipsychotic and an antiemetic. …
Matched Description: … It is used as an antipsychotic and an antiemetic. …
N-methylnicotinamide
N-methylnicotinamide is an experimental drug with no approved indication or marketed formulation. It is a metabolite of niacinamide/nicotinamide and niacin/nicotinic acid (vitamin B3), and as such N-methylnicotinamide is used to diagnose niacin deficiency by measuring N-methylnicotinamide in the urine.
Experimental
Matched Synonyms: … N-Methyl nicotineamide ... N-Methyl-3-pyridinecarboxamide …
Matched Description: … It is a metabolite of niacinamide/nicotinamide and niacin/nicotinic acid (vitamin B3), and as such N-methylnicotinamide …
Matched Categories: … Bile and Liver Therapy ... Alimentary Tract and Metabolism …
Matched Description: … It is a metabolite of niacinamide/nicotinamide and niacin/nicotinic acid (vitamin B3), and as such N-methylnicotinamide …
Matched Categories: … Bile and Liver Therapy ... Alimentary Tract and Metabolism …
IKT-001Pro
Investigational
Matched Synonyms: … Methanesulfonate-1-sec-butoxycarbonyloxymethyl-1-methyl-4-{4-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2- …
Displaying drugs 676 - 700 of 1895 in total