Displaying drugs 676 - 700 of 2937 in total
Aceclofenac
Aceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. It is reported to have a higher anti-inflammatory action or at least comparable effects than conventional NSAIDs in double-blind studies [A19667, A19668, A19670]. Aceclofenac potently inhibits the...
Approved
Investigational
Matched Synonyms: … glycolic acid [o-(2,6-dichloroanilino)phenyl]acetate ester ... 2-[(2,6-dichlorophenyl)amino]phenylacetoxyacetic acid ... 2-[(2',6'-dichlorophenyl)amino]phenylacetoxyacetic acid …
Matched Iupac: … 2-[(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetyl)oxy]acetic acid …
Matched Description: … Aceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and ... analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. ... synthesis of prostaglandins, which are inflammatory mediators that cause pain, swelling, inflammation, and …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Acids, Carbocyclic ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain …
Matched Iupac: … 2-[(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetyl)oxy]acetic acid …
Matched Description: … Aceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and ... analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. ... synthesis of prostaglandins, which are inflammatory mediators that cause pain, swelling, inflammation, and …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Acids, Carbocyclic ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain …
Desoxycorticosterone acetate
Approved
Matched Synonyms: … Desoxycortone acetate ... Deoxycorticosterone acetate ... 11-deoxycorticosterone acetate …
Matched Name: … Desoxycorticosterone acetate …
Matched Iupac: … -oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl acetate …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Name: … Desoxycorticosterone acetate …
Matched Iupac: … -oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl acetate …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Frexalimab
Frexalimab is under investigation in clinical trial NCT06141486 (Efficacy and Safety Study of Frexalimab (SAR441344) in Adults With Nonrelapsing Secondary Progressive Multiple Sclerosis).
Investigational
Matched Synonyms: … Immunoglobulin G1 (272-arginine,325-alanine), anti-(human CD40 ligand) (human-mus musculus monoclonal …
Matched Description: … Frexalimab is under investigation in clinical trial NCT06141486 (Efficacy and Safety Study of Frexalimab …
Matched Description: … Frexalimab is under investigation in clinical trial NCT06141486 (Efficacy and Safety Study of Frexalimab …
Phenprocoumon
Coumarin derivative that acts as a long-acting oral anticoagulant.
Approved
Investigational
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … PHENPROCOUMON ACIS 3MG TAB …
Matched Products: … PHENPROCOUMON ACIS 3MG TAB …
Etidronic acid
Etidronic acid is a first generation bisphosphonate similar to clodronic acid and tiludronic acid. These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. Etidronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate zoledronic acid, ibandronic acid,...
Approved
Matched Synonyms: … Etidronic acid ... acide étidronique ... acidum etidronicum …
Matched Name: … Etidronic acid …
Matched Iupac: … (1-hydroxy-1-phosphonoethyl)phosphonic acid …
Matched Description: … Etidronic acid is a first generation bisphosphonate similar to [clodronic acid] and [tiludronic acid] ... ], [ibandronic acid], [minodronic acid], and [risedronic acid]. ... A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and …
Matched Categories: … etidronic acid and calcium, sequential ... Drugs Affecting Bone Structure and Mineralization ... etidronic acid …
Matched Name: … Etidronic acid …
Matched Iupac: … (1-hydroxy-1-phosphonoethyl)phosphonic acid …
Matched Description: … Etidronic acid is a first generation bisphosphonate similar to [clodronic acid] and [tiludronic acid] ... ], [ibandronic acid], [minodronic acid], and [risedronic acid]. ... A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and …
Matched Categories: … etidronic acid and calcium, sequential ... Drugs Affecting Bone Structure and Mineralization ... etidronic acid …
Abiraterone
Abiraterone is a potent, irreversible, and selective inhibitor of 17 αhydroxylase/C17,20-lyase (CYP17), an enzyme expressed in testicular, adrenal, and prostatic tumour tissues, to regulate androgen biosynthesis.[A3811, A260880, L40968] Abiraterone was first approved by the FDA and EMA on April, July, and September 2011, respectively. It is used to treat metastatic...
Approved
Matched Description: … hydrolysis by esterases, abiraterone acetate was developed as an orally bioavailable prodrug with enhanced ... Abiraterone is a potent, irreversible, and selective inhibitor of 17 αhydroxylase/C17,20-lyase (CYP17 ... ] and September 2011,[A260880] respectively. …
Matched Salts name: … Abiraterone acetate …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... niraparib and abiraterone ... abiraterone and prednisolone ... Hormone Antagonists and Related Agents ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … Abiraterone Acetate ... Abiraterone acetate ... Abiratred Abiraterone Acetate Tablets 250mg …
Matched Salts name: … Abiraterone acetate …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... niraparib and abiraterone ... abiraterone and prednisolone ... Hormone Antagonists and Related Agents ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … Abiraterone Acetate ... Abiraterone acetate ... Abiratred Abiraterone Acetate Tablets 250mg …
Levocetirizine
Levocetirizine is a selective histamine H1 antagonist used to treat a variety of allergic symptoms.[A181748,A181790,L7694] It is the R enantiomer of cetirizine. Levocetirizine has greater affinity for the histamine H1 receptor than cetirizine. Levocetirizine was granted FDA approval in 1995.
Approved
Matched Synonyms: … 2-(2-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid …
Matched Iupac: … 2-(2-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid …
Matched Description: … Levocetirizine is a selective histamine H1 antagonist used to treat a variety of allergic ... [L7694] Levocetirizine has greater affinity for the histamine H1 receptor than cetirizine. …
Matched Categories: … Cetirizine and isomer ... Histamine Agents ... Histamine Antagonists ... Histamine H1 Antagonists ... Histamine H1 Antagonists, Non-Sedating …
Matched Products: … HISTRINE LEVO ... HISTADINE 5MG TABLETAS RECUBIERTAS ... HISTADINE® 50 MG/100 ML SOLUCIÓN ORAL …
Matched Iupac: … 2-(2-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid …
Matched Description: … Levocetirizine is a selective histamine H1 antagonist used to treat a variety of allergic ... [L7694] Levocetirizine has greater affinity for the histamine H1 receptor than cetirizine. …
Matched Categories: … Cetirizine and isomer ... Histamine Agents ... Histamine Antagonists ... Histamine H1 Antagonists ... Histamine H1 Antagonists, Non-Sedating …
Matched Products: … HISTRINE LEVO ... HISTADINE 5MG TABLETAS RECUBIERTAS ... HISTADINE® 50 MG/100 ML SOLUCIÓN ORAL …
Disomotide
Disomotide is a synthetic peptide cancer vaccine.
Investigational
Matched Synonyms: … L-valine, l-isoleucyl-l-methionyl-l-.alpha. ... -aspartyl-l-glutaminyl-l-valyl-l-prolyl-l-phenylalanyl-l-seryl- …
OM-301
Investigational
Matched Synonyms: … Glycine, L-prolyl-L-prolyl-L-leucyl-L-seryl-L-glutaminyl-L-alpha-glutamyl-L-threonyl-Lphenylalanyl- L-seryl-L-alpha-aspartyl-L-leucyl-L-tryptophyl-L-lysyl-L-leucyl-L-leucyl-L-lysyl-Llysyl ... - L-tryptophyl-L-lysyl-L-methionyl-L-arginyl-L-arginyl-L-asparaginy …
Levomefolic acid
Levomefolic acid (INN) is the metabolite of folic acid (Vitamin B9) and it is a predominant active form of folate found in foods and in the blood circulation, accounting for 98% of folates in human plasma . It is transported across the membranes including the blood-brain barrier into various tissues...
Approved
Investigational
Matched Synonyms: … acid ... N-[4-[[[(6S)-2-Amino-3,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl]methyl]amino]benzoyl]-L-glutamic ... Levomefolic acid …
Matched Name: … Levomefolic acid …
Matched Iupac: … -amino-5-methyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido}pentanedioic acid …
Matched Description: … Levomefolic acid (INN) is the metabolite of folic acid (Vitamin B9) and it is a predominant active form ... regulation of homocysteine, where it methylates homocysteine and forms methionine and tetrahydrofolate ... of folate found in foods and in the blood circulation, accounting for 98% of folates in human plasma …
Matched Mixtures name: … Levomefolate Calcium Acetylcysteine and Mecobalamin Algal ... Levomefolate Calcium and Schizochytrium DHA ... Levomefolate Calcium and Schizochytrium DHA …
Matched Categories: … Folic Acid and Derivatives ... Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Amino Acids, Acidic ... Amino Acids …
Matched Name: … Levomefolic acid …
Matched Iupac: … -amino-5-methyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido}pentanedioic acid …
Matched Description: … Levomefolic acid (INN) is the metabolite of folic acid (Vitamin B9) and it is a predominant active form ... regulation of homocysteine, where it methylates homocysteine and forms methionine and tetrahydrofolate ... of folate found in foods and in the blood circulation, accounting for 98% of folates in human plasma …
Matched Mixtures name: … Levomefolate Calcium Acetylcysteine and Mecobalamin Algal ... Levomefolate Calcium and Schizochytrium DHA ... Levomefolate Calcium and Schizochytrium DHA …
Matched Categories: … Folic Acid and Derivatives ... Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Amino Acids, Acidic ... Amino Acids …
Mafenide
Mafenide is a sulfonamide-type antimicrobial agent used to treat severe burns. It acts by reducing the bacterial population present in the burn tissue and promotes healing of deep burns. In 1998, mafenide acetate was approved under the FDA’s accelerated approval regulations. In November 2022, the use of mafenide acetate (powder...
Approved
Vet approved
Withdrawn
Matched Description: … It acts by reducing the bacterial population present in the burn tissue and promotes healing of deep ... [L36773] In 1998, mafenide acetate was approved under the FDA’s accelerated approval regulations. ... In November 2022, the use of mafenide acetate (powder for 5% topical solution) was withdrawn by the FDA …
Matched Salts name: … Mafenide Acetate …
Matched Categories: … Folic Acid Antagonists ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … Mafenide acetate ... Mafenide Acetate …
Matched Salts name: … Mafenide Acetate …
Matched Categories: … Folic Acid Antagonists ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … Mafenide acetate ... Mafenide Acetate …
Denosumab
Denosumab is a novel, fully human IgG2 monoclonal antibody specific to receptor activator of nuclear factor kappa-B ligand (RANKL), suppresses bone resorption via inhibiting RANK-mediated activation of osteoclasts. It is the first and currently the only RANKL inhibitor approved to prevent osteoclast-mediated bone loss. Chemically, it consists of 2 heavy...
Approved
Matched Description: … 215 amino acids and each heavy chain consisting of 448 amino acids with 4 intramolecular disulfides. ... It is the first and currently the only RANKL inhibitor approved to prevent osteoclast-mediated bone loss ... [A263071] Chemically, it consists of 2 heavy and 2 light chains, with each light chain consisting of …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Drugs Affecting Bone Structure and Mineralization …
Matched Products: … Prolia ... PROLIA ... PROLIA® …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Drugs Affecting Bone Structure and Mineralization …
Matched Products: … Prolia ... PROLIA ... PROLIA® …
N-PYRIDOXYL-D-GLUTAMIC ACID-5'-MONOPHOSPHATE
Experimental
Matched Name: … N-PYRIDOXYL-D-GLUTAMIC ACID-5'-MONOPHOSPHATE …
Matched Iupac: … (2R)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]pentanedioic acid …
Matched Iupac: … (2R)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]pentanedioic acid …
alpha-Methylleucine
Experimental
Matched Synonyms: … 2-Methyl-L-leucine …
Matched Iupac: … (2S)-2-amino-2,4-dimethylpentanoic acid …
Matched Iupac: … (2S)-2-amino-2,4-dimethylpentanoic acid …
3-Cyclohexyl-L-alanine
Experimental
Matched Synonyms: … β-Cyclohexyl-alanine ... beta-Cyclohexyl-alanine ... beta-Cyclohexyl-L-alanine …
Matched Name: … 3-Cyclohexyl-L-alanine …
Matched Iupac: … (2S)-2-amino-3-cyclohexylpropanoic acid …
Matched Name: … 3-Cyclohexyl-L-alanine …
Matched Iupac: … (2S)-2-amino-3-cyclohexylpropanoic acid …
2-Hydroxy-Tryptophan
Experimental
Matched Name: … 2-Hydroxy-Tryptophan …
Matched Iupac: … (2S)-2-amino-3-(2-hydroxy-1H-indol-3-yl)propanoic acid …
Matched Iupac: … (2S)-2-amino-3-(2-hydroxy-1H-indol-3-yl)propanoic acid …
Indoximod
Indoximod has been used in trials studying the treatment of Glioma, Melanoma, Ependymoma, Gliosarcoma, and Lung Cancer, among others.
Investigational
Matched Synonyms: … (2R)-2-amino-3-(1-methyl-1H-indol-3-yl)propanoic acid ... 1-methyl-D-tryptophan …
Matched Iupac: … (2R)-2-amino-3-(1-methyl-1H-indol-3-yl)propanoic acid …
Matched Description: … Indoximod has been used in trials studying the treatment of Glioma, Melanoma, Ependymoma, Gliosarcoma, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Tryptophan Oxygenase, antagonists & inhibitors ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Matched Iupac: … (2R)-2-amino-3-(1-methyl-1H-indol-3-yl)propanoic acid …
Matched Description: … Indoximod has been used in trials studying the treatment of Glioma, Melanoma, Ependymoma, Gliosarcoma, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Tryptophan Oxygenase, antagonists & inhibitors ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
2,3-Dimercapto-1-propanesulfonic acid
Experimental
Matched Synonyms: … 2,3-Dimercaptopropanesulfonic acid ... 2,3-Dimercapto-1-propane sulfonate …
Matched Name: … 2,3-Dimercapto-1-propanesulfonic acid …
Matched Iupac: … 2,3-disulfanylpropane-1-sulfonic acid …
Matched Name: … 2,3-Dimercapto-1-propanesulfonic acid …
Matched Iupac: … 2,3-disulfanylpropane-1-sulfonic acid …
Furoyl-Leucine
Experimental
Matched Name: … Furoyl-Leucine …
Matched Iupac: … (2S)-2-[(furan-2-yl)formamido]-4-methylpentanoic acid …
Matched Iupac: … (2S)-2-[(furan-2-yl)formamido]-4-methylpentanoic acid …
D-Methionine
Approved
Experimental
Investigational
Matched Name: … D-Methionine …
Matched Iupac: … (2R)-2-amino-4-(methylsulfanyl)butanoic acid …
Matched Mixtures name: … NUTRINEAL PD]4 Peritoneal Dialysis Solution with 1.1% Amino Acids …
Matched Iupac: … (2R)-2-amino-4-(methylsulfanyl)butanoic acid …
Matched Mixtures name: … NUTRINEAL PD]4 Peritoneal Dialysis Solution with 1.1% Amino Acids …
Imino-Tryptophan
Experimental
Matched Name: … Imino-Tryptophan …
Matched Iupac: … 2-imino-3-(1H-indol-3-yl)propanoic acid …
Matched Iupac: … 2-imino-3-(1H-indol-3-yl)propanoic acid …
PARA-NITROBENZYL GLUTARYL GLYCINIC ACID
Experimental
Matched Name: … PARA-NITROBENZYL GLUTARYL GLYCINIC ACID …
Matched Iupac: … 2-(4-{[(4-nitrophenyl)methyl]carbamoyl}butanamido)acetic acid …
Matched Iupac: … 2-(4-{[(4-nitrophenyl)methyl]carbamoyl}butanamido)acetic acid …
Pegargiminase
Pegargiminase is an anticancer agent.
Investigational
Matched Synonyms: … Arginine deiminase pegylated ... Pegylated arginine deiminase …
Matched Categories: … Enzymes and Coenzymes …
Matched Categories: … Enzymes and Coenzymes …
beta-2-Thienyl-L-alanine
Experimental
Matched Synonyms: … L-3-(2-thienyl)alanine ... beta-(2-Thienyl)-L-alanine …
Matched Name: … beta-2-Thienyl-L-alanine …
Matched Iupac: … (2S)-2-amino-3-(thiophen-2-yl)propanoic acid …
Matched Name: … beta-2-Thienyl-L-alanine …
Matched Iupac: … (2S)-2-amino-3-(thiophen-2-yl)propanoic acid …
Deutarserine
Deutarserine is under investigation in clinical trial NCT04158687 (A Phase 2 Study to Evaluate the Safety and Efficacy of CTP-692 as an Adjunctive Treatment in Adults With Schizophrenia).
Investigational
Matched Synonyms: … D-serine-2-d …
Matched Description: … Deutarserine is under investigation in clinical trial NCT04158687 (A Phase 2 Study to Evaluate the Safety and …
Matched Description: … Deutarserine is under investigation in clinical trial NCT04158687 (A Phase 2 Study to Evaluate the Safety and …
Displaying drugs 676 - 700 of 2937 in total