Displaying drugs 676 - 700 of 1066 in total
Etevritamab
Investigational
Matched Synonyms: … RECEPTOR, RECEPTOR TYROSINE-PROTEIN KINASE ERBB-1, ERBB1, HER1, HER-1, ERBB) VARIANT III (EGFRVIII)) AND …
Fazpilodemab
Fazpilodemab is under investigation in clinical trial NCT04171765 (A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of BFKB8488A Compared With Placebo in Participants With Non-alcoholic Steatohepatitis).
Investigational
Matched Synonyms: … immunoglobulin G1-kappa, anti-[Homo sapiens KLB (klotho beta, b-Klotho)] and anti-[Homo sapiens FGFR1 …
Matched Description: … Fazpilodemab is under investigation in clinical trial NCT04171765 (A Study to Evaluate the Efficacy, Safety, and …
Matched Description: … Fazpilodemab is under investigation in clinical trial NCT04171765 (A Study to Evaluate the Efficacy, Safety, and …
Fluoroestradiol F-18
Fluoroestradiol F-18 is an imaging agent used with positron emission tomography (PET) to detect estrogen receptor-positive breast cancer lesions. The ability to image ER-positive tumors in vivo is advantageous in that, while helping to visualize tumor progression/regression, it may also be used to assess for heterogeneity in ER expression across...
Approved
Matched Synonyms: … F-18 16 alpha-Fluoroestradiol ... 16-alpha-(18-Fluoro)-17betaestradiol ... 16-alpha-(18F)Fluoro-17beta-estradiol …
Matched Description: … PETNET Solutions, Inc. and Zionexa USA under the brand name Cerianna. ... [A203912] Fluoroestradiol F-18 was first granted FDA approval in May 2020, and will be developed by …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … PETNET Solutions, Inc. and Zionexa USA under the brand name Cerianna. ... [A203912] Fluoroestradiol F-18 was first granted FDA approval in May 2020, and will be developed by …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
UDP-alpha-D-xylose
The decarboxylation product of UDPglucuronic acid, which is used for formation of the xylosides of seryl hydroxyl groups in mucoprotein synthesis. Also forms plant xylans.
Experimental
Matched Name: … UDP-alpha-D-xylose …
Alpha-Cyclodextrin (Cyclohexa-Amylose)
Experimental
Matched Name: … Alpha-Cyclodextrin (Cyclohexa-Amylose) …
Alpha-Methylene Adenosine Monophosphate
Experimental
Matched Name: … Alpha-Methylene Adenosine Monophosphate …
PHENYLAMINOIMIDAZO(1,2-ALPHA)PYRIDINE
Experimental
Matched Name: … PHENYLAMINOIMIDAZO(1,2-ALPHA)PYRIDINE …
(2R)-2-Acetamido-3-(octadecyloxy)propyl 2-(methylsulfanyl)ethyl hydrogen phosphate
Experimental
Matched Synonyms: … 1-Octadecyl-2-acetamido-2-deoxy-SN-glycerol-3-phosphoethylmethyl sulfide …
Mosedipimod
Mosedipimod has been used in trials studying the supportive care and treatment of Chemotherapy-induced Neutropenia.
Investigational
Matched Synonyms: … 1-Palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol …
Matched Description: … Mosedipimod has been used in trials studying the supportive care and treatment of Chemotherapy-induced …
Matched Description: … Mosedipimod has been used in trials studying the supportive care and treatment of Chemotherapy-induced …
Aphidicolin
Aphidicolin is an antimitotic and antiviral metabolite of the mould Cephalosporium aphidicola. It inhibits DNA polymerase alpha and blocks DNA replication.[A259157, A259162]
Investigational
Matched Synonyms: … .,5.alpha.,17.alpha ... 9,15-cyclo-c,18-dinor-14,15-secoandrostane-4,17-dimethanol, 3,17-dihydroxy-4-methyl-, (3.alpha.,4.alpha …
Matched Description: … It inhibits DNA polymerase alpha and blocks DNA replication.[A259157, A259162] ... Aphidicolin is an antimitotic and antiviral metabolite of the mould _Cephalosporium aphidicola_. …
Matched Description: … It inhibits DNA polymerase alpha and blocks DNA replication.[A259157, A259162] ... Aphidicolin is an antimitotic and antiviral metabolite of the mould _Cephalosporium aphidicola_. …
fb-PMT
Investigational
Matched Synonyms: … -diiodo-4-(1-methylene-1,2,3-triazol-4-ylmethoxy)phenoxy]-3,5-diiodophenyl}acetic acid)polyethylene glycol ... -diiodo-4-(1-methylen-1,2,3-triazol-4-ylmethoxy)phenoxy]-3,5-diiodophenyl}acetic acid) polyethylene glycol …
Biperiden
A muscarinic antagonist that has effects in both the central and peripheral nervous systems. It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. It has also been used to alleviate extrapyramidal symptoms induced by phenothiazine derivatives and reserpine.
Approved
Investigational
Matched Synonyms: … alpha-5-norbornen-2-yl-alpha-phenyl-1-piperidinepropanol ... alpha-bicyclo[2.2.1]hept-5-en-2-yl-alpha-phenyl-1-piperidinepropanol …
Matched Description: … A muscarinic antagonist that has effects in both the central and peripheral nervous systems. ... It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. ... It has also been used to alleviate extrapyramidal symptoms induced by phenothiazine derivatives and reserpine …
Matched Description: … A muscarinic antagonist that has effects in both the central and peripheral nervous systems. ... It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. ... It has also been used to alleviate extrapyramidal symptoms induced by phenothiazine derivatives and reserpine …
Bromocriptine
Bromocriptine mesylate is a semisynthetic ergot alkaloid derivative with potent dopaminergic activity. It inhibits prolactin secretion and may be used to treat dysfunctions associated with hyperprolactinemia. Bromocriptine is also indicated for the management of signs and symptoms of Parkinsonian Syndrome, as well as the treatment of acromegaly. Bromocriptine has been...
Approved
Investigational
Withdrawn
Matched Synonyms: … 2-Bromo-alpha-ergocryptine ... 2-Bromo-alpha-ergokryptin ... 2-Bromo-alpha-ergokryptine …
Matched Description: … It inhibits prolactin secretion and may be used to treat dysfunctions associated with hyperprolactinemia ... Bromocriptine is also indicated for the management of signs and symptoms of Parkinsonian Syndrome, as ... Bromocriptine has been associated with pulmonary fibrosis, and can also cause sustained suppression of …
Matched Categories: … Ergot Alkaloids and Derivatives ... Genito Urinary System and Sex Hormones ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Adrenergic alpha-Agonists ... Adrenergic alpha-Antagonists …
Matched Description: … It inhibits prolactin secretion and may be used to treat dysfunctions associated with hyperprolactinemia ... Bromocriptine is also indicated for the management of signs and symptoms of Parkinsonian Syndrome, as ... Bromocriptine has been associated with pulmonary fibrosis, and can also cause sustained suppression of …
Matched Categories: … Ergot Alkaloids and Derivatives ... Genito Urinary System and Sex Hormones ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Adrenergic alpha-Agonists ... Adrenergic alpha-Antagonists …
Zilucoplan
Zilucoplan is a 15 amino-acid, synthetic macrocyclic peptide. It is a complement inhibitor that works to prevent the activation of C5, which is a complement protein involved in the innate immune system to initiate inflammatory responses. On October 17, 2023, zilucoplan gained its first FDA approval for the treatment of...
Approved
Matched Synonyms: … N2-ACETYL-L-LYSYL-L-VALYL-L-.ALPHA.-GLUTAMYL-L-ARGINYL-L-PHENYLALANYL-L-.ALPHA. ... -ASPARTYL-N-METHYL-L-.ALPHA. ... -GLUTAMYL-L-ARGINYL-L-PHENYLALANYL-L-.ALPHA.-ASPARTYL-N-METHYL-L-.ALPHA.-ASPARTYL-3-METHYL- …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Sivopixant
Investigational
Matched Synonyms: … -methyl-2,6-dioxo-4-((4-(2-pyridinyloxy)phenyl)imino)-, (.alpha.s,4e)- ... 1,3,5-triazine-1(2h)-propanoic acid, 3-((4-chlorophenyl)methyl)tetrahydro-.alpha. …
NNZ-2591
NNZ-2591 (cyclo-L-glycyl-L-2-allylproline) is an investigational synthetic analog of cyclic glycine-proline (cGP), a breakdown product of human insulin-like growth factor 1 (IGF-1), that has been chemically modified to increase its half-life, stability, and oral bioavailability. It is currently under development by Neuren Pharmaceuticals for the symptomatic treatment of Angelman, Phelan-McDermid, and...
Investigational
Matched Synonyms: … Cyclo(-L-glycyl-L-2-allylproline) …
Matched Description: … It was granted Orphan Drug Designation by the FDA in October 2019[L11103] and was granted a patent by ... NNZ-2591 (cyclo-L-glycyl-L-2-allylproline)[A189390] is an investigational synthetic analog of cyclic ... under development by Neuren Pharmaceuticals for the symptomatic treatment of Angelman, Phelan-McDermid, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … It was granted Orphan Drug Designation by the FDA in October 2019[L11103] and was granted a patent by ... NNZ-2591 (cyclo-L-glycyl-L-2-allylproline)[A189390] is an investigational synthetic analog of cyclic ... under development by Neuren Pharmaceuticals for the symptomatic treatment of Angelman, Phelan-McDermid, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Choriogonadotropin alfa
Recombinant human chorionic gonadotropin with 2 subunits, alpha = 92 residues, beta = 145 residues, each with N-and O-linked carbohydrate moieties linked to ASN-52 and ASN-78 (on alpha subunit) and ASN-13, ASN-30, SER-121, SER-127, SER-132 and SER-138 (on beta subunit). The primary structure of the alpha-chain of r-hCG is identical...
Approved
Matched Synonyms: … Choriogonadotropin alpha …
Matched Description: … with N-and O-linked carbohydrate moieties linked to ASN-52 and ASN-78 (on alpha subunit) and ASN-13, ... and LH. ... ASN-30, SER-121, SER-127, SER-132 and SER-138 (on beta subunit). …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gonadotropins and Antigonadotropins ... Sex Hormones and Modulators of the Genital System …
Matched Description: … with N-and O-linked carbohydrate moieties linked to ASN-52 and ASN-78 (on alpha subunit) and ASN-13, ... and LH. ... ASN-30, SER-121, SER-127, SER-132 and SER-138 (on beta subunit). …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gonadotropins and Antigonadotropins ... Sex Hormones and Modulators of the Genital System …
NBI-98782
Approved
Investigational
Matched Synonyms: … (+)-.alpha.-dihydrotetrabenazine ... (+)-alpha-dihydrotetrabenazine ... Dihydrotetrabenazine, (+)-.alpha.- …
Triheptanoin
Triheptanoin is a source of heptanoate fatty acids, which can be metabolized without the enzymes of long chain fatty acid oxidation. In clinical trials, patients with long chain fatty acid oxidation disorders (lc-FAODs) treated with triheptanoin are less likely to develop hypoglycemia, cardiomyopathy, rhabdomyolysis, and hepatomegaly.[A214812,A214817] Complications in lc-FAOD patients...
Approved
Investigational
Matched Synonyms: … Glycerol triheptanoate …
Matched Description: … treated with triheptanoin are less likely to develop hypoglycemia, cardiomyopathy, rhabdomyolysis, and …
Matched Categories: … Alimentary Tract and Metabolism ... Various Alimentary Tract and Metabolism Products …
Matched Description: … treated with triheptanoin are less likely to develop hypoglycemia, cardiomyopathy, rhabdomyolysis, and …
Matched Categories: … Alimentary Tract and Metabolism ... Various Alimentary Tract and Metabolism Products …
Displaying drugs 676 - 700 of 1066 in total