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Displaying drugs 7051 - 7075 of 10532 in total

PF-06459988

PF-06459988 is under investigation in clinical trial NCT02297425 (A Study For Patients With EGFRm (Epidermal Growth Factor Receptor Mutant) Lung Cancer).
Investigational
Matched Iupac: … ]-4-methoxypyrrolidin-1-yl]prop-2-en-1-one ... 1-[(3R,4R)-3-[({5-chloro-2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)methyl …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Balipodect

Balipodect is under investigation in clinical trial NCT01892189 (Effects of TAK-063 on Preventing Ketamine-Induced Brain Activity Changes as Well as Psychotic-Like Symptoms in Healthy Male Adults).
Investigational
Matched Iupac: … 1-[2-fluoro-4-(1H-pyrazol-1-yl)phenyl]-5-methoxy-3-(1-phenyl-1H-pyrazol-5-yl)-1,4-dihydropyridazin-4- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Topramezone

Topramezone is under investigation in clinical trial NCT00559520 (The Role of Preoperative Oral Immunonutrition in Major Vascular Surgery).
Investigational
Matched Iupac: … 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-4-methanesulfonyl-2-methylbenzoyl]-1-methyl-1H-pyrazol-5-ol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Seltorexant

Seltorexant is under investigation in clinical trial NCT03494907 (A Study to Evaluate the Effects of Single-dose Seltorexant on Electrocardiogram Intervals in Healthy Adult Participants).
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Vamotinib

Vamotinib (PF-114) is under investigation in clinical trial NCT02885766 (Study to Evaluate Tolerability, Safety, Pharmacokinetics and Preliminary Efficacy of PF-114 for Oral Administration in Adults With Ph+ Chronic Myeloid Leukemia, Which is Resistant to the 2-nd Generation Bcr-Abl Inhibitors or Has T315I Mutation in the BCR-ABL Gene).
Investigational
Matched Iupac: … 4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}-3-(2-{[1,2,4]triazolo[4,3-a …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

BMS-754807

BMS-754807 is under investigation in clinical trial NCT00908024 (Combination Study of BMS-754807 and Erbitux® in Subjects With Advanced or Metastatic Solid Tumors).
Investigational
Matched Iupac: … (2S)-1-{4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl}-N-(6-fluoropyridin …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Ciclonium bromide

Experimental
Matched Iupac: … [2-(1-{bicyclo[2.2.1]hept-5-en-2-yl}-1-phenylethoxy)ethyl]diethylmethylazanium bromide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

PF-05212377

PF-05212377 is under investigation in clinical trial NCT01712074 (Study Evaluating Thesafety and Efficacy of PF-05212377 or Placebo in Subjects With Alzheimer's Disease With Existing Neuropsychiatric Symptoms on Donepezil).
Investigational
Matched Iupac: … 1-(benzenesulfonyl)-2-methyl-4-(piperazin-1-yl)-1H-1,3-benzodiazole …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Milvexian

Milvexian is under investigation in clinical trial NCT03766581 (A Study on BMS-986177 for the Prevention of a Stroke in Patients Receiving Aspirin and Clopidogrel).
Investigational
Matched Iupac: … (9R,13S)-13-{4-[5-chloro-2-(4-chloro-1H-1,2,3-triazol-1-yl)phenyl]-6-oxo-1,6-dihydropyrimidin-1-yl}-3 ... -(difluoromethyl)-9-methyl-3,4,7,15-tetraazatricyclo[12.3.1.0^{2,6}]octadeca-1(17),2(6),4,14(18),15-pentaen …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Poseltinib

Poseltinib is under investigation in clinical trial NCT02628028 (A Study of LY3337641 in Rheumatoid Arthritis).
Investigational
Matched Iupac: … N-{3-[(2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}furo[3,2-d]pyrimidin-4-yl)oxy]phenyl}prop-2-enamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Siremadlin

Investigational
Matched Iupac: … [3,4-d]imidazol-5-yl]-1-methyl-1,2-dihydropyridin-2-one ... 5-chloro-3-[(6S)-6-(4-chlorophenyl)-2-(2,4-dimethoxypyrimidin-5-yl)-4-oxo-1-(propan-2-yl)-1H,4H,5H,6H-pyrrolo …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

LY-2090314

Ly2090314 has been used in trials studying the treatment of Leukemia, Advanced Cancer, and Pancreatic Cancer.
Investigational
Matched Iupac: … 3-[6-fluoro-10-(piperidine-1-carbonyl)-1,10-diazatricyclo[6.4.1.0^{4,13}]trideca-2,4,6,8(13)-tetraen- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

E7107

E7107 has been used in trials studying the treatment of Cancer.
Investigational
Matched Iupac: … oxacyclododec-4-en-6-yl 4-cycloheptylpiperazine-1-carboxylate ... 2R,3R)-3-[(2R,3S)-3-hydroxypentan-2-yl]oxiran-2-yl]-6-methylhepta-2,4-dien-2-yl]-3,7-dimethyl-12-oxo-1- …

Setipiprant

Setipiprant has been investigated for the treatment of Seasonal Allergic Rhinitis.
Investigational
Matched Iupac: … 2-[8-fluoro-2-(naphthalene-1-carbonyl)-1H,2H,3H,4H,5H-pyrido[4,3-b]indol-5-yl]acetic acid …

Simenepag isopropyl

Simenepag isopropyl has been used in trials studying the treatment of Ocular Hypertension and Glaucoma, Open-Angle.
Investigational
Matched Iupac: … propan-2-yl 5-({[(2R)-1-{4-[(1S)-1-hydroxyhexyl]phenyl}-5-oxopyrrolidin-2-yl]methoxy}methyl)thiophene …

19-norandrostenedione

19-Norandrostenedione refers to two steroid isomers that were once marketed as dietary supplements and mainly used by body builders. After 2005, 19-Norandrostenedione was regulated in the United States as a schedule III controlled substance, as well as banned from use in competitive sports by the World Anti-Doping Agency. In the...
Experimental
Illicit

AGS-499

Investigational

Romilkimab

Romilkimab is under investigation in clinical trial NCT02345070 (Efficacy and Safety of SAR156597 in the Treatment of Idiopathic Pulmonary Fibrosis).
Investigational

2-Iminobiotin

Experimental
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Dextrin 2-sulfate

Investigational
Matched Categories: … HIV-1 …

AT-7519

AT7519 is a selective inhibitor of certain Cyclin Dependent Kinases (CDKs) leading to tumour regression. It is developed by Astex for the treatment of solid tumours and haematological malignancies.
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Litronesib

Litronesib has been used in trials studying the treatment of Solid Tumors, Ovarian Cancer, Gastric Cancer, Prostate Cancer, and Acute Leukaemia, among others.
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …

SB-705498

SB-705498 has been investigated for the treatment of Rhinitis, Chronic Cough, and Non-allergic Rhinitis.
Investigational
Matched Iupac: … 1-(2-bromophenyl)-3-[(3R)-1-[5-(trifluoromethyl)pyridin-2-yl]pyrrolidin-3-yl]urea …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

GSK-424887

Gsk424887 has been used in trials studying the basic science and treatment of Depressive Disorder and Anxiety Disorder.
Investigational
Matched Iupac: … N-[(1S)-1-(3-chloronaphthalen-1-yl)ethyl]-2-[4-(4-fluorophenyl)-1-methylpiperidin-4-yl]-N-methylacetamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

ABT-072

ABT-072 is under investigation in clinical trial NCT00890318 (A Study in Healthy Adult Subjects to Evaluate the Safety, Tolerability, and Pharmacokinetic Profiles of Multiple Doses of ABT-072 Used to Treat Hepatitis C).
Investigational
Matched Iupac: … N-{4-[(1E)-2-[3-tert-butyl-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-2-methoxyphenyl]ethenyl]phenyl …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 7051 - 7075 of 10532 in total