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Displaying drugs 7076 - 7100 of 12984 in total
Casopitant
Investigational
Matched Iupac: … (2R,4S)-4-(4-acetylpiperazin-1-yl)-N-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl]-2-(4-fluoro-2-methylphenyl ... )-N-methylpiperidine-1-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Neurokinin-1 Receptor Antagonists …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Neurokinin-1 Receptor Antagonists …
Tinostamustine
Tinostamustine is under investigation in clinical trial NCT03452930 (Tinostamustine With or Without Radiation Therapy in Treating Patients With Newly Diagnosed MGMT-Unmethylated Glioblastoma).
Investigational
Matched Iupac: … 7-{5-[bis(2-chloroethyl)amino]-1-methyl-1H-1,3-benzodiazol-2-yl}-N-hydroxyheptanamide …
Matched Salts cas: … 1793059-58-1 …
Matched Salts cas: … 1793059-58-1 …
(2S)-2-(biphenyl-4-yloxy)-3-phenylpropanoic acid
Experimental
Matched Name: … (2S)-2-(biphenyl-4-yloxy)-3-phenylpropanoic acid …
Matched Iupac: … (2S)-2-{[1,1'-biphenyl]-4-yloxy}-3-phenylpropanoic acid …
Matched Iupac: … (2S)-2-{[1,1'-biphenyl]-4-yloxy}-3-phenylpropanoic acid …
Magnesium salicylate
Magnesium salicylate is a non-steroidal anti-inflammatory drug (NSAID) used to treat mild to moderate pain. It is available in several over-the-counter (OTC) formulations. Though the recommended doseage is 1160 mg every six hours, per package directions of the Doan's OTC brand (580 mg magnesium salicylate tetrahydrate, equivalent to 934.4 mg...
Experimental
Albumin-stabilized nanoparticle (130 nm)
Investigational
Hypericin
Hypericin is under investigation for the treatment of Cutaneous T-cell Lymphoma.
Investigational
Matched Iupac: … hexahydroxy-13,16-dimethyloctacyclo[13.11.1.1^{2,10}.0^{3,8}.0^{4,25}.0^{19,27}.0^{21,26}.0^{14,28}]octacosa-1( …
Polaprezinc
Polaprezinc is a chelated form of zinc and L-carnosine. It is a zinc-related medicine approved for the first time in Japan, which has been clinically used to treat gastric ulcers [L1307, L1308]. It was determined that polaprezinc may be effective in pressure ulcer treatment . A study in 2013 showed...
Experimental
Matched Iupac: … (4S)-3-(3-aminopropanoyl)-4-[(1H-imidazol-5-yl)methyl]-1-oxa-3-aza-2-zincacyclopentan-5-one …
Tetrahydrouridine
Tetrahydrouridine has been used in trials studying the treatment of Neoplasms, Lung Neoplasms, Breast Neoplasms, Sickle Cell Disease, and Head and Neck Cancer, among others.
Investigational
Matched Iupac: … 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-1,3-diazinan-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
AGG-523
AGG-523 is under investigation in clinical trial NCT00380900 (Study Evaluating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Ascending Doses in Healthy subjects and in subjects with osteoarthritis).
Investigational
Matched Iupac: … (4S)-4-({[1,1'-biphenyl]-4-yl}formamido)-4-{[1-(4-fluorophenyl)-2-methylpropan-2-yl]carbamoyl}butanoic …
N4-Hydroxycytidine
N4-Hydroxyctidine, or EIDD-1931, is a ribonucleoside analog which induces mutations in RNA virions.[A193008,A193011] N4-hydroxycytidine was first described in the literature in 1980 as a potent mutagen of bacteria and phage. It has shown antiviral activity against Venezuelan equine encephalitis virus, and the human coronavirus HCoV-NL63 in vitro. N4-hydroxycytodine has been...
Experimental
Matched Synonyms: … 4-N-Hydroxycytidine ... Uridine, 4-oxime ... N(4)-Hydroxycytidine …
Matched Iupac: … 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(hydroxyamino)-1,2-dihydropyrimidin-2- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(hydroxyamino)-1,2-dihydropyrimidin-2- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Olacaftor
Olacaftor is under investigation in clinical trial NCT02951182 (A Study Evaluating the Safety and Efficacy of VX-440 Combination Therapy in Subjects With Cystic Fibrosis).
Investigational
Matched Iupac: … N-(benzenesulfonyl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine …
INCB-9471
INCB-9471 is a novel, orally available CCR5 antagonist that is part of a new class of drugs to treat HIV/AIDS. It is a potent, selective inhibitor of the HIV-1 virus.
Investigational
Matched Iupac: … 5-{4-[(3S)-4-[(1R,2R)-2-ethoxy-5-(trifluoromethyl)-2,3-dihydro-1H-inden-1-yl]-3-methylpiperazin-1-yl] ... -4-methylpiperidine-1-carbonyl}-4,6-dimethylpyrimidine …
Matched Description: … It is a potent, selective inhibitor of the HIV-1 virus. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … It is a potent, selective inhibitor of the HIV-1 virus. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Dirithromycin
Dirithromycin is a macrolide glycopeptide antibiotic used to treat many different types of bacterial infections, such as bronchitis, pneumonia, tonsillitis, and even skin infections.
Experimental
Matched Iupac: … (1R,2R,3R,6R,7S,8S,9R,10R,12R,13S,15R,17S)-9-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan ... -2-yl]oxy}-3-ethyl-2,10-dihydroxy-7-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-15 …
Fimasartan
Fimasartan is an angiotensin II receptor antagonist (ARB) drug employed in the treatment of both hypertension and heart failure. It has been found to be safe when administered with hydrochlorothiazide (a diuretic) in clinical trials. Fimasartan was initially approved September 9th, 2010 in South Korea and is marketed under the...
Investigational
Matched Iupac: … 2-(2-butyl-4-methyl-6-oxo-1-{[2'-(1H-1,2,3,4-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl}-1,6-dihydropyrimidin …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
L-tyrosinamide
Experimental
Matched Synonyms: … (2S)-2-amino-3-(4-hydroxyphenyl)propanamide …
Matched Iupac: … (2S)-2-amino-3-(4-hydroxyphenyl)propanamide …
Matched Iupac: … (2S)-2-amino-3-(4-hydroxyphenyl)propanamide …
3-nitro-L-tyrosine
Experimental
Matched Synonyms: … (2S)-2-amino-3-(4-hydroxy-3-nitrophenyl)propanoic acid …
Matched Iupac: … (2S)-2-amino-3-(4-hydroxy-3-nitrophenyl)propanoic acid …
Matched Iupac: … (2S)-2-amino-3-(4-hydroxy-3-nitrophenyl)propanoic acid …
4-[4-AMINO-6-(2,6-DICHLORO-PHENOXY)-[1,3,5]TRIAZIN-2-YLAMINO]-BENZONITRILE
Experimental
Matched Name: … 4-[4-AMINO-6-(2,6-DICHLORO-PHENOXY)-[1,3,5]TRIAZIN-2-YLAMINO]-BENZONITRILE …
Matched Iupac: … 4-{[4-amino-6-(2,6-dichlorophenoxy)-1,3,5-triazin-2-yl]amino}benzonitrile …
Matched Iupac: … 4-{[4-amino-6-(2,6-dichlorophenoxy)-1,3,5-triazin-2-yl]amino}benzonitrile …
4-{[(Z)-(5-oxo-2-phenyl-1,3-oxazol-4(5H)-ylidene)methyl]amino}butanoic acid
Experimental
Matched Name: … 4-{[(Z)-(5-oxo-2-phenyl-1,3-oxazol-4(5H)-ylidene)methyl]amino}butanoic acid …
Matched Iupac: … 4-{[(5-oxo-2-phenyl-4,5-dihydro-1,3-oxazol-4-ylidene)methyl]amino}butanoic acid …
Matched Iupac: … 4-{[(5-oxo-2-phenyl-4,5-dihydro-1,3-oxazol-4-ylidene)methyl]amino}butanoic acid …
CDX-1135
CDX-1135, formerly TP-10, is a soluble, recombinant human Complement Receptor Type 1 (sCR1) developed by Avant Immunotherapeutics (now Celldex). It was investigated in clinical trials for post-cardiopulmonary bypass syndrome and kidney damage.
Investigational
Matched Description: … CDX-1135, formerly TP-10, is a soluble, recombinant human Complement Receptor Type 1 (sCR1) developed …
2,4-DIAMINO-1,5-DIPHENYL-3-HYDROXYPENTANE
Experimental
Matched Iupac: … (2S,4S)-2,4-diamino-1,5-diphenylpentan-3-ol …
(3,4-Dihydroxy-Phenyl)-Triphenyl-Arsonium
Experimental
R450
R450 is an alpha 1 antagonist that acts to tighten the muscle tone in the bladder. It is being considered for treatment of stress-related urinary incontinence. Phase IIa data for the drug show it reduced the number of incontinent episodes compared to placebo with minimal cardiovascular effects.
Investigational
Matched Description: … R450 is an alpha 1 antagonist that acts to tighten the muscle tone in the bladder. …
OSE-2101
Investigational
Displaying drugs 7076 - 7100 of 12984 in total