Displaying drugs 7201 - 7225 of 12049 in total
Flubentylosin
Investigational
Matched Synonyms: … 4''-(p-fluorobenzyl)tylosin a ... 4b-o-((4-fluorophenyl)methyl)tylosin ... Tylosin, 4b-o-((4-fluorophenyl)methyl)- …
Matched Iupac: … 2-[(4R,5S,6S,7R,9R,11E,13E,15R,16R)-6-{[(2R,3R,4R,5S,6R)-4-(dimethylamino)-5-{[(2S,4R,5S,6S)-5-[(4-fluorophenyl ... -1-oxacyclohexadeca-11,13-dien-7-yl]acetaldehyde ... )methoxy]-4-hydroxy-4,6-dimethyloxan-2-yl]oxy}-3-hydroxy-6-methyloxan-2-yl]oxy}-16-ethyl-4-hydroxy-15 ... -({[(2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methyloxan-2-yl]oxy}methyl)-5,9,13-trimethyl-2,10-dioxo …
Matched Iupac: … 2-[(4R,5S,6S,7R,9R,11E,13E,15R,16R)-6-{[(2R,3R,4R,5S,6R)-4-(dimethylamino)-5-{[(2S,4R,5S,6S)-5-[(4-fluorophenyl ... -1-oxacyclohexadeca-11,13-dien-7-yl]acetaldehyde ... )methoxy]-4-hydroxy-4,6-dimethyloxan-2-yl]oxy}-3-hydroxy-6-methyloxan-2-yl]oxy}-16-ethyl-4-hydroxy-15 ... -({[(2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methyloxan-2-yl]oxy}methyl)-5,9,13-trimethyl-2,10-dioxo …
SGS518
SGS518, a novel antagonist for the 5HT6 subtype of the serotonin receptor, is being developed as a treatment for Cognitive Impairment Associated with Schizophrenia (CIAS).
Investigational
BMS-564929
BMS-564929 is an investigational therapeutic agent built to be a selective androgen receptor modulator (SARM). So far, it has been developed by Bristol-Myers Squibb for the symptomatic treatment of andropause.
Experimental
Matched Iupac: … 4-[(7R,7aS)-7-hydroxy-1,3-dioxo-hexahydro-1H-pyrrolo[1,2-c]imidazol-2-yl]-2-chloro-3-methylbenzonitrile …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
CH-5132799
CH5132799 has been used in trials studying the treatment of Solid Tumors.
Investigational
Matched Iupac: … 5-[7-methanesulfonyl-2-(morpholin-4-yl)-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-4-yl]pyrimidin-2-amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
SLN500
SLN500 is a synthetic double-strand small interfering ribonucleic acid (siRNA) oligonucleotide drug directed against C3 messenger RNA
Investigational
Onapristone
Onapristone has been used in trials studying the treatment of Prostate Cancer, Recurrent Prostate Cancer, Metastatic Prostate Cancer, Androgen-independent Prostate Cancer, and Progesterone Receptor Positive Tumor: Max 1 Line of Prior Chemotherapy, no Prior Hormone Therapy.
Investigational
Matched Iupac: … [8.7.0.0^{2,7}.0^{11,15}]heptadeca-1,6-dien-5-one ... (10S,11S,14S,15R,17R)-17-[4-(dimethylamino)phenyl]-14-hydroxy-14-(3-hydroxypropyl)-15-methyltetracyclo …
Matched Description: … Prostate Cancer, Androgen-independent Prostate Cancer, and Progesterone Receptor Positive Tumor: Max 1 …
Matched Description: … Prostate Cancer, Androgen-independent Prostate Cancer, and Progesterone Receptor Positive Tumor: Max 1 …
Interferon Gamma
Interferon gamma is a Type 1 inflammatory cytokine and the only type II interferon. It has antitumor properties, antiviral activities, and important immunoregulatory functions. The interferon is primarily produced by activated T lymphocytes and natural killer cells.
Investigational
Matched Description: … Interferon gamma is a Type 1 inflammatory cytokine and the only type II interferon. …
Balanol Analog 2
Experimental
Matched Iupac: … (3R,4R)-3-(4-hydroxybenzamido)azepan-4-yl 4-(2-hydroxybenzoyl)benzoate …
PF-03635659
Pf03635659 has been used in trials studying the treatment of Chronic Obstructive Pulmonary Disease.
Investigational
Matched Iupac: … 5-[3-(3-hydroxyphenoxy)azetidin-1-yl]-5-methyl-2,2-diphenylhexanamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Melevodopa
Experimental
4-(trifluoromethyl)phenol
Experimental
Matched Synonyms: … 4-trifluoromethylphenol ... 4-hydroxybenzotrifluoride …
Matched Name: … 4-(trifluoromethyl)phenol …
Matched Iupac: … 4-(trifluoromethyl)phenol …
Matched Name: … 4-(trifluoromethyl)phenol …
Matched Iupac: … 4-(trifluoromethyl)phenol …
PPL-100
Investigational
Matched Iupac: … methyl N-[(1S)-1-{[(5S)-6-hydroxy-5-[N-(2-methylpropyl)4-aminobenzenesulfonamido]hexyl]carbamoyl}-2,2 …
4-[3-Hydroxyanilino]-6,7-Dimethoxyquinazoline
Experimental
Matched Name: … 4-[3-Hydroxyanilino]-6,7-Dimethoxyquinazoline …
Matched Iupac: … 3-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol …
Matched Iupac: … 3-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol …
Oxyphenisatin
A laxative that undergoes enterohepatic circulation. It may cause jaundice.
Investigational
Withdrawn
Matched Synonyms: … 3,3-Bis(4-hydroxyphenyl)oxindole ... 1,3-Dihydro-3,3-bis(4-hydroxyphenyl)-2H-indol-2-one …
Matched Iupac: … 3,3-bis(4-hydroxyphenyl)-2,3-dihydro-1H-indol-2-one …
Matched Iupac: … 3,3-bis(4-hydroxyphenyl)-2,3-dihydro-1H-indol-2-one …
4-[(4-Imidazo[1,2-a]Pyridin-3-Ylpyrimidin-2-Yl)Amino]Benzenesulfonamide
Experimental
Matched Name: … 4-[(4-Imidazo[1,2-a]Pyridin-3-Ylpyrimidin-2-Yl)Amino]Benzenesulfonamide …
Matched Iupac: … 4-[(4-{imidazo[1,2-a]pyridin-3-yl}pyrimidin-2-yl)amino]benzene-1-sulfonamide …
Matched Iupac: … 4-[(4-{imidazo[1,2-a]pyridin-3-yl}pyrimidin-2-yl)amino]benzene-1-sulfonamide …
2-(Biphenyl-4-Sulfonyl)-1,2,3,4-Tetrahydro-Isoquinoline-3-Carboxylic Acid
Experimental
Matched Name: … 2-(Biphenyl-4-Sulfonyl)-1,2,3,4-Tetrahydro-Isoquinoline-3-Carboxylic Acid …
Matched Iupac: … (3R)-2-{[1,1'-biphenyl]-4-sulfonyl}-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid …
Matched Iupac: … (3R)-2-{[1,1'-biphenyl]-4-sulfonyl}-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid …
ATL1101
ATL1101 is a second-generation antisense drug designed to block the synthesis of the IGF-1 receptor, a protein involved in the regulation of cell overgrowth in psoriasis. ATL1101 is being developed as a cream for the topical treatment of mild to moderate cases of psoriasis.
Investigational
Matched Description: … ATL1101 is a second-generation antisense drug designed to block the synthesis of the IGF-1 receptor, …
Linsitinib
An orally bioavailable small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) with potential antineoplastic activity. IGF-1R inhibitor OSI-906 selectively inhibits IGF-1R, which may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis.
Investigational
Matched Iupac: … (1s,3r)-3-[8-amino-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutan-1-ol …
Matched Description: … An orally bioavailable small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … An orally bioavailable small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
PF-06273340
Pf 06273340 is under investigation in clinical trial NCT01934738 (A Study to Evaluate Safety, Toleration and Time Course of Plasma Concentration of Multiple Oral Doses of PF-06273340 in Healthy Subjects of Two AgeGroups, Aged 18-55 Years (Group 1) and Aged 56-75 Years (Group 2)).
Investigational
Matched Iupac: … N-{5-[2-amino-7-(1-hydroxy-2-methylpropan-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl]pyridin-3-yl}- ... 2-(5-chloropyridin-2-yl)acetamide …
Matched Description: … of Multiple Oral Doses of PF-06273340 in Healthy Subjects of Two AgeGroups, Aged 18-55 Years (Group 1) …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … of Multiple Oral Doses of PF-06273340 in Healthy Subjects of Two AgeGroups, Aged 18-55 Years (Group 1) …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Arbaclofen Placarbil
Arbaclofen Placerbil is a prodrug of Arbaclofen, which is a selective gamma-amino-butyric acid type B receptor agonist and the R-enantiomer of baclofen. It was discovered, and has been patented by XenoPort as a new chemical entity with an improved pharmacokinetic profile compared to baclofen, which allows for sustained release properties....
Investigational
Matched Iupac: … (3R)-3-(4-chlorophenyl)-4-({[(1S)-2-methyl-1-[(2-methylpropanoyl)oxy]propoxy]carbonyl}amino)butanoic …
(4R)-4-(3-butoxy-4-methoxybenzyl)imidazolidin-2-one
Experimental
Matched Name: … (4R)-4-(3-butoxy-4-methoxybenzyl)imidazolidin-2-one …
Matched Iupac: … (4R)-4-[(3-butoxy-4-methoxyphenyl)methyl]imidazolidin-2-one …
Matched Iupac: … (4R)-4-[(3-butoxy-4-methoxyphenyl)methyl]imidazolidin-2-one …
Bufotenine
A hallucinogenic serotonin analog found in frog or toad skins, mushrooms, higher plants, and mammals, especially in the brains, plasma, and urine of schizophrenics. Bufotenin has been used as a tool in CNS studies and misused as a psychedelic.
Experimental
Illicit
Matched Synonyms: … 3-[2-(dimethylamino)ethyl]-5-indolol ... 5-hydroxy-N,N-dimethyltryptamine ... 3-[2-(dimethylamino)ethyl]indol-5-ol …
Matched Iupac: … 3-[2-(dimethylamino)ethyl]-1H-indol-5-ol …
Matched Iupac: … 3-[2-(dimethylamino)ethyl]-1H-indol-5-ol …
1,1'-HEXANE-1,6-DIYLBIS(1H-IMIDAZOLE)
Experimental
Matched Iupac: … 1-[6-(1H-imidazol-1-yl)hexyl]-1H-imidazole …
N-Hydroxy-4-phosphonobutanamide
Experimental
Matched Synonyms: … N-hydroxy-4-phosphono-butanamide …
Matched Name: … N-Hydroxy-4-phosphonobutanamide …
Matched Name: … N-Hydroxy-4-phosphonobutanamide …
Displaying drugs 7201 - 7225 of 12049 in total