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Displaying drugs 701 - 725 of 6216 in total

Hexylresorcinol

Hexylresorcinol is a substituted dihydroxybenzene. It exhibits antiseptic, anthelmintic, and local anesthetic properties. It can be found in topical applications for minor skin infections and in oral solutions or throat lozenges for pain relief and first aid antiseptic. The compound may also be used commonly in various commercial cosmetic anti-aging...
Approved

Rifampin

Rifampin, also known as rifampicin, is a broad-spectrum antimicrobial that was first discovered in 1965 and clinically used in 1968. Rifampin is used to treat tuberculosis and works by inhibiting the microbial DNA-dependent RNA polymerase (RNAP).
Approved
Matched Synonyms: … 3-(((4-Methyl-1-piperazinyl)imino)methyl)rifamycin SV …
Matched Salts cas: … 38776-75-9 …
Matched Mixtures name: … PRO TB 3 KID ... RINCURE ® 3 FDC TABLETAS CON PELICULA …

Danicopan

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare acquired hematologic disease characterized by hemolysis, thrombophilia, and bone marrow dysfunction.[A263501,L50417] Both hemolysis and thrombophilia are mediated primarily by the complement system. Standard therapy for PNH involves the use of complement C5 inhibitors (e.g. eculizumab, ravulizumab) which are effective in mitigating complement-mediated intravascular...
Approved
Investigational
Matched Synonyms: … (2S,4R)-1-(2-(3-acetyl-5-(2-methylpyrimidine-5-yl)-1H-indazol-1-yl)acetyl)-N-(6-bromopyridine-2-yl)-4 ... (2S,4R)-1-(2-(3-acetyl-5-(2-methylpyrimidin-5-yl)-1H-indazol-1-yl)acetyl)-N-(6-bromopyridin-2-yl)-4-fluoropyrrolidine …
Matched Iupac: … (2S,4R)-1-{2-[3-acetyl-5-(2-methylpyrimidin-5-yl)-1H-indazol-1-yl]acetyl}-N-(6-bromopyridin-2-yl)-4-fluoropyrrolidine …

Betula lenta pollen

Betula lenta pollen is the pollen of the Betula lenta plant. Betula lenta pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … 9 Tree Mix ... 9 Tree Mix ... 9 Tree Mix …

Reteplase

Human tissue plasminogen activator, purified, glycosylated, 355 residues purified from CHO cells. Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and delete certain portions of human tPA. Retavase is a deletion mutein of human tPA formed by deleting various amino acids present in endogenous human tPA. Retavase...
Approved
Investigational
Matched Synonyms: … Human t-PA (residues 1-3 and 176-527) …
Matched Description: … Retavase contains 355 of the 527 amino acids of native human tPA (amino acids 1-3 and 176-527), and retains …

Fludarabine

Fludarabine is a chemotherapeutic agent used in the treatment of hematological malignancies. It is commonly marketed under the brand name Fludara.
Approved
Matched Iupac: … (2R,3S,4S,5R)-2-(6-amino-2-fluoro-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol …
Matched Salts cas: … 75607-67-9 …

Sulpiride

Sulpiride first appeared in published literature in 1967. Clinical studies show a greater effect on treating the negative symptoms of schizophrenia rather than positive symptoms at low doses, though the effects are more equal at higher doses. Sulpiride is not approved by the FDA, Health Canada, or the EMA; though...
Approved
Investigational
Matched Products: … MERESA 100MG / 3 ML ENJEKSİYONLUK ÇÖZLELTİ, 100 ADET ... MERESA 100MG / 3 ML ENJEKSİYONLUK ÇÖZLELTİ, 6 ADET …

Nateglinide

Nateglinide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It belongs to the meglitinide class of short-acting insulin secretagogues, which act by binding to β cells of the pancreas to stimulate insulin release. Nateglinide is an amino acid derivative that induces an early insulin...
Approved
Investigational
Matched Iupac: … (2R)-3-phenyl-2-{[(1r,4r)-4-(propan-2-yl)cyclohexyl]formamido}propanoic acid …
Matched Mixtures name: … NATMET 120/1000 MG TEDAVI PAKETI, 90+90 ADET ... NATMET 120/500 MG TEDAVI PAKETI, 90+90 ADET ... NATMET 120/850 MG TEDAVI PAKETI, 90+90 ADET …

Oleic Acid

An unsaturated fatty acid that is the most widely distributed and abundant fatty acid in nature. It is used commercially in the preparation of oleates and lotions, and as a pharmaceutical solvent. (Stedman, 26th ed)
Approved
Investigational
Vet approved
Matched Iupac: … (9E)-octadec-9-enoic acid …
Matched Salts cas: … 142-17-6 …

Dydrogesterone

A synthetic progestational hormone with no androgenic or estrogenic properties. Unlike many other progestational compounds, dydrogesterone produces no increase in temperature and does not inhibit ovulation.
Approved
Investigational
Withdrawn

Quercus alba pollen

Quercus alba pollen, or oak white pollen, is a non-standardized allergen extract used for the diagnosis and treatment of allergic disease to grass pollen. It can be subcutaneously administered to initiate an immune response in case of an allergic reaction. Diagnostic allergenic extracts are primarily indicated for establishing clinical relevance...
Approved
Matched Mixtures name: … 9 Tree Mix ... 9 Tree Mix ... 9 Tree Mix …

Naltrexone

Derivative of noroxymorphone that is the N-cyclopropylmethyl congener of naloxone. It is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and has been proposed for the treatment of heroin addiction. The FDA has approved naltrexone for the treatment of alcohol dependence.
Approved
Investigational
Vet approved
Matched Synonyms: … 17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-one ... 17-(Cyclopropylmethyl)-4,5α-epoxy-3,14-dihydroxymorphinan-6-one …

Fraxinus americana pollen

Fraxinus americana pollen is the pollen of the Fraxinus americana plant. Fraxinus americana pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … 9 Tree Mix ... 9 Tree Mix ... 9 Tree Mix …

Panobinostat

Panobinostat is an oral deacetylace (DAC) inhibitor approved on February 23, 2015 by the FDA for the treatment of multiple myeloma. The approval was accelerated based on progression-free survival, therefore confirmatory trials by the sponsor to demonstrate clinical efficacy in multiple myeloma treatment are in progress of being conducted. Panobinostat...
Approved
Investigational
Matched Synonyms: … (2E)-N-hydroxy-3-[4-({[2-(2-methyl-1H-indol-3-yl)ethyl]amino}methyl)phenyl]acrylamide ... 2-PROPENAMIDE, N-HYDROXY-3-(4-(((2-(2-METHYL-1H-INDOL-3-YL)ETHYL)AMINO)METHYL)PHENYL)-, (2E)- …
Matched Iupac: … (2E)-N-hydroxy-3-[4-({[2-(2-methyl-1H-indol-3-yl)ethyl]amino}methyl)phenyl]prop-2-enamide …

Esterified estrogens

Esterified estrogens contain a mixture of estrogenic substances; the principle component is estrone. Preparations contain 75% to 85% sodium estrone sulfate and 6% to 15% sodium equilin sulfate such that the total is not <90%. Esterified estrogens are a man-made mixture of estrogens that are used to treat symptoms of...
Approved
Matched Description: … 75% to 85% sodium estrone sulfate and 6% to 15% sodium equilin sulfate such that the total is not <90% …

Acer saccharinum pollen

Acer saccharinum pollen is the pollen of the Acer saccharinum plant. Acer saccharinum pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … 9 Tree Mix ... 9 Tree Mix ... 3 Maple Pollen Mix …

Valbenazine

Valbenazine is a modified metabolite of tetrabenazine, and it is currently being approved for the treatment of various movement disorders, particularly tardive dyskinesia and chorea associated with Huntington's disease.[L47885,A261135] Tardive dyskinesia has long been regarded as a consequence of anti-dopamine receptor therapy, and until 2008 with the advent of tetrabenazine,...
Approved
Investigational
Matched Iupac: … 2S)-2-amino-3-methylbutanoate ... (2R,3R,11bR)-9,10-dimethoxy-3-(2-methylpropyl)-1H,2H,3H,4H,6H,7H,11bH-pyrido[2,1-a]isoquinolin-2-yl ( …
Matched Description: … This approval was supported by positive results in multiple trials, including the KINECT-HD Phase 3 study …

Levothyroxine

Levothyroxine is a synthetically produced form of thyroxine, a major endogenous hormone secreted by the thyroid gland. Also known as L-thyroxine or the brand name product Synthroid, levothyroxine is used primarily to treat hypothyroidism, a condition where the thyroid gland is no longer able to produce sufficient quantities of the...
Approved
Matched Iupac: … (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid …
Matched Description: … sufficient quantities of the thyroid hormones T4 (tetraiodothyronine or thyroxine) and T3< ... [F4633] T4 and T3 act on nearly every cell of the body, but have a particularly ... of the physiological effects of the thyroid hormones; T4 and T3 have a relative …
Matched Mixtures name: … Np Thyroid 90 ... NP Thyroid 90 ... NP Thyroid 90 …

Desloratadine

Desloratadine is a second generation, tricyclic antihistamine that which has a selective and peripheral H1-antagonist action. It is the active descarboethoxy metabolite of loratidine (a second generation histamine). Desloratidine has a long-lasting effect and does not cause drowsiness because it does not readily enter the central nervous system.
Approved
Investigational
Matched Iupac: … 13-chloro-2-(piperidin-4-ylidene)-4-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaene …
Matched Mixtures name: … DESMONT 5/10 MG 90 FILM KAPLI TABLET ... AIRCOMB 2,5 MG/4 MG GRANÜL İÇEREN SAŞE, 90 ADET ... DESMONT 2.5 MG/4 MG ÇİĞNEME TABLETİ, 90 ADET …

Lusutrombopag

Lusutrombopag is an orally bioavailable thrombopoietin receptor (TPOR) agonist developed by Shionogi &amp; Company (Osaka, Japan). TPOR is a regulatory target site for endogenous thrombopoietin, which acts as a primary cytokine to promote megakaryocyte proliferation and differentiation, and affect other hematopoietic lineages as well, including erythroid, granulocytic and lymphoid lineages...
Approved
Investigational
Matched Iupac: … (2E)-3-{2,6-dichloro-4-[(4-{3-[(1S)-1-(hexyloxy)ethyl]-2-methoxyphenyl}-1,3-thiazol-2-yl)carbamoyl]phenyl …
Matched Description: … thrombocytopenia who were undergoing an invasive procedure with a platelet count less than 50 x 10^9/ …

Technetium Tc-99m tilmanocept

Technetium Tc-99m tilmanocept is a radiopharmaceutical diagnostic imaging agent approved by the U.S. Food and Drug Administration (FDA) for the imaging of lymph nodes with or without scintigraphic imaging. It is a macromolecule consisting of multiple units of diethylenetriaminepentaacetic acid (DTPA) and mannose, each covalently attached to a 10 kDa...
Approved
Investigational

Fluoxetine

Fluoxetine is a 2nd generation antidepressant categorized as a selective serotonin reuptake inhibitor (SSRI). It gained FDA approval in 1987 and although it was initially intended for the treatment of depression, today it is commonly prescribed to manage depression in addition to various other pathologies.
Approved
Vet approved
Matched Synonyms: … (+-)-N-Methyl-3-phenyl-3-((alpha,alpha,alpha-trifluoro-P-tolyl)oxy)propylamine …
Matched Iupac: … methyl({3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl})amine …
Matched Mixtures name: … TARGET 3 MG /25 MG KAPSUL, 90 ADET ... TARGET 3 MG /25 MG KAPSUL, 30 ADET ... FLUXOPIN 3 MG/25 MG KAPSÜL ,30 KAPSÜL …

Gallium citrate Ga-67

Gallium citrate Ga 67 is the citrate salt of the radioisotope gallium Ga 67. Although the mechanism is unknown, gallium Ga 67 concentrates in lysosomes and is bound to a soluble intracellular protein in certain viable primary and metastatic tumors and focal sites of inflammation, allowing scintigraphic localization. Ga-67 scintigraphy...
Approved
Matched Iupac: … (67Ga)gallium(3+) 2-hydroxypropane-1,2,3-tricarboxylate …

Brexanolone

As of March 2019, brexanolone - developed and made available commercially by Sage Therapeutics Inc. as the brand name product Zulresso - is the first drug to have ever been approved by the US FDA specifically for the treatment of postpartum depression (PPD) in adult females . Since PPD, like...
Approved
Investigational

Deferiprone

Deferiprone is an oral iron chelator used as a second line agent in thalassemia syndromes when iron overload from blood transfusions occurs. Thalassemias are a type of hereditary anaemia due a defect in the production of hemoglobin. As a result, erythropoiesis, the production of new red blood cells, is impaired....
Approved
Matched Synonyms: … 1,2-Dimethyl-3-hydroxypyrid-4-one ... 3-Hydroxy-1,2-dimethyl-4(1H)-pyridone …
Matched Iupac: … 3-hydroxy-1,2-dimethyl-1,4-dihydropyridin-4-one …
Displaying drugs 701 - 725 of 6216 in total