Displaying drugs 701 - 725 of 4319 in total
Phosphoaminophosphonic acid guanylate ester
A non-hydrolyzable analog of GTP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. It binds tightly to G-protein in the presence of Mg2+. The nucleotide is a potent stimulator of adenylate cyclase.
Experimental
Matched Synonyms: … Guanosine 5'-[beta,gamma-imido]triphosphate …
Matched Name: … Phosphoaminophosphonic acid guanylate ester …
Matched Iupac: … dihydro-2H-purin-9-yl)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}amino)phosphonic acid …
Matched Description: … A non-hydrolyzable analog of GTP, in which the oxygen atom bridging the beta to the gamma phosphate is …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Name: … Phosphoaminophosphonic acid guanylate ester …
Matched Iupac: … dihydro-2H-purin-9-yl)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}amino)phosphonic acid …
Matched Description: … A non-hydrolyzable analog of GTP, in which the oxygen atom bridging the beta to the gamma phosphate is …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Aminophosphonic acid-guanylate ester
Experimental
Matched Name: … Aminophosphonic acid-guanylate ester …
Matched Iupac: … ,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy})phosphinic acid …
Matched Iupac: … ,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy})phosphinic acid …
Phosphomethylphosphonic acid guanosyl ester
Experimental
Matched Name: … Phosphomethylphosphonic acid guanosyl ester …
Matched Iupac: … oxo-6,9-dihydro-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)methyl]phosphonic acid …
Matched Iupac: … oxo-6,9-dihydro-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)methyl]phosphonic acid …
Phosphoaminophosphonic Acid-Adenylate Ester
5'-Adenylic acid, monoanhydride with imidodiphosphoric acid. An analog of ATP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. It is a potent competitive inhibitor of soluble and membrane-bound mitochondrial ATPase and also inhibits ATP-dependent reactions of oxidative phosphorylation. [PubChem]
Experimental
Matched Name: … Phosphoaminophosphonic Acid-Adenylate Ester …
Matched Iupac: … 9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}amino)phosphonic acid …
Matched Description: … It is a potent competitive inhibitor of soluble and membrane-bound mitochondrial ATPase and also inhibits ... 5'-Adenylic acid, monoanhydride with imidodiphosphoric acid. ... An analog of ATP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a …
Matched Iupac: … 9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}amino)phosphonic acid …
Matched Description: … It is a potent competitive inhibitor of soluble and membrane-bound mitochondrial ATPase and also inhibits ... 5'-Adenylic acid, monoanhydride with imidodiphosphoric acid. ... An analog of ATP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a …
Phosphomethylphosphonic acid guanylate ester
Experimental
Matched Name: … Phosphomethylphosphonic acid guanylate ester …
Matched Iupac: … -yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)methyl](hydroxy)phosphoryl}oxy)phosphonic acid …
Matched Iupac: … -yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)methyl](hydroxy)phosphoryl}oxy)phosphonic acid …
(R)-etodolac
Investigational
Matched Synonyms: … Pyrano(3,4-b)indole-1-acetic acid, 1,8-diethyl-1,3,4,9-tetrahydro-, (r)- ... (1r)-1,8-diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid ... Pyrano(3,4-b)indole-1-acetic acid, 1,8-diethyl-1,3,4,9-tetrahydro-, (1r)- …
Matched Name: … (R)-etodolac …
Matched Name: … (R)-etodolac …
Methyl salicylate 2-ethylbutyrate
Experimental
Matched Synonyms: … Salicylic acid, methyl ester, 2-ethylbutyrate …
9(S)-HODE
Experimental
Matched Synonyms: … alpha-Dimorphecolic acid ... (9S,10E,12Z)-9-hydroxyoctadeca-10,12-dienoic acid …
Matched Iupac: … (9S,10E,12Z)-9-hydroxyoctadeca-10,12-dienoic acid …
Matched Iupac: … (9S,10E,12Z)-9-hydroxyoctadeca-10,12-dienoic acid …
Camptothecin
Camptothecin is an alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selectively inhibits the nuclear enzyme DNA topoisomerase, type I. Several semisynthetic analogs of camptothecin have demonstrated antitumor activity.
Experimental
Matched Synonyms: … 21,22-Secocamptothecin-21-oic acid lactone ... 20(S)-camptothecine …
Matched Iupac: … -hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0^{2,11}.0^{4,9}.0^{15,20}]henicosa-1(21),2,4,6,8,10,15(20 …
Matched Iupac: … -hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0^{2,11}.0^{4,9}.0^{15,20}]henicosa-1(21),2,4,6,8,10,15(20 …
Aspartic acid
One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
Approved
Nutraceutical
Matched Synonyms: … Aspartic acid ... Acidum asparticum ... 2-Aminosuccinic acid …
Matched Name: … Aspartic acid …
Matched Iupac: … (2S)-2-aminobutanedioic acid …
Matched Description: … One of the non-essential amino acids commonly occurring in the L-form. ... It is found in animals and plants, especially in sugar cane and sugar beets. …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... Premasol - sulfite-free (Amino Acid) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Amino Acids, Dicarboxylic ... Excitatory Amino Acids …
Matched Name: … Aspartic acid …
Matched Iupac: … (2S)-2-aminobutanedioic acid …
Matched Description: … One of the non-essential amino acids commonly occurring in the L-form. ... It is found in animals and plants, especially in sugar cane and sugar beets. …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... Premasol - sulfite-free (Amino Acid) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Amino Acids, Dicarboxylic ... Excitatory Amino Acids …
Simmondsia chinensis seed
Simmondsia chinensis seed is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Gray Box Bush Seed ... Jojoba Seed ... Goatnut Seed …
Matched Name: … Simmondsia chinensis seed …
Matched Description: … Simmondsia chinensis seed is a plant/plant extract used in some OTC (over-the-counter) products. …
Matched Mixtures name: … WELLAGE Deep Layer Silky Facial Oil …
Matched Name: … Simmondsia chinensis seed …
Matched Description: … Simmondsia chinensis seed is a plant/plant extract used in some OTC (over-the-counter) products. …
Matched Mixtures name: … WELLAGE Deep Layer Silky Facial Oil …
Sparfosic acid
Sparfosic acid is a solid. This compound belongs to the n-acyl-alpha amino acids. These are compounds containing an alpha amino acid which bears an acyl group at the terminal nitrogen atom. This substance is known to target aspartate carbamoyltransferase catalytic chain and CAD protein.
Experimental
Matched Synonyms: … Acidum sparfosicum ... Sparfosic acid ... N-(phosphonacetyl)-L-aspartic acid …
Matched Name: … Sparfosic acid …
Matched Iupac: … (2S)-2-(2-phosphonoacetamido)butanedioic acid …
Matched Description: … This substance is known to target aspartate carbamoyltransferase catalytic chain and CAD protein. ... Sparfosic acid is a solid. This compound belongs to the n-acyl-alpha amino acids. ... These are compounds containing an alpha amino acid which bears an acyl group at the terminal nitrogen …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Acids, Acyclic ... Carboxylic Acids …
Matched Name: … Sparfosic acid …
Matched Iupac: … (2S)-2-(2-phosphonoacetamido)butanedioic acid …
Matched Description: … This substance is known to target aspartate carbamoyltransferase catalytic chain and CAD protein. ... Sparfosic acid is a solid. This compound belongs to the n-acyl-alpha amino acids. ... These are compounds containing an alpha amino acid which bears an acyl group at the terminal nitrogen …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Acids, Acyclic ... Carboxylic Acids …
Ketoprofen
Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties.
Approved
Vet approved
Matched Synonyms: … 3-Benzoyl-alpha-methylbenzeneacetic acid ... 2-(3-Benzoylphenyl)propionic acid ... 3-Benzoylhydratropic acid …
Matched Iupac: … 2-(3-benzoylphenyl)propanoic acid …
Matched Description: … and antipyretic properties. ... Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antiinflammatory and Antirheumatic Products ... Ketoprofen and isomer ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain …
Matched Products: … Orafen - Sup RT 100mg ... KETOFEN SR 200 MG KAPSÜL, 20 ADET ... MİVELİN PR 200 MG KAPSÜL , 20 ADET …
Matched Iupac: … 2-(3-benzoylphenyl)propanoic acid …
Matched Description: … and antipyretic properties. ... Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antiinflammatory and Antirheumatic Products ... Ketoprofen and isomer ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain …
Matched Products: … Orafen - Sup RT 100mg ... KETOFEN SR 200 MG KAPSÜL, 20 ADET ... MİVELİN PR 200 MG KAPSÜL , 20 ADET …
Risperidone
Risperidone is a second-generation antipsychotic (SGA) medication used in the treatment of a number of mood and mental health conditions including schizophrenia and bipolar disorder. It is one of the most widely used SGAs. Paliperidone, another commonly used SGA, is the primary active metabolite of risperidone (i.e. 9-hydroxyrisperidone). Schizophrenia and...
Approved
Investigational
Matched Iupac: … 3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-2-methyl-4H,6H,7H,8H,9H-pyrido[1,2-a]pyrimidin …
Matched Description: … Risperidone is a second-generation antipsychotic (SGA) medication used in the treatment of a number of mood and ... mental health conditions including schizophrenia and bipolar disorder. ... D2 and serotonergic 5-HT2A activity, resulting in overactivity of central mesolimbic pathways and mesocortical …
Matched Categories: … Adrenergic alpha-Antagonists ... Adrenergic alpha-1 Receptor Antagonists …
Matched Products: … PERILIFE 1 MG FİLM TABLET, 20 ADET ... PERILIFE 2 MG FİLM TABLET, 20 ADET ... PERILIFE 3 MG FİLM TABLET, 20 ADET …
Matched Description: … Risperidone is a second-generation antipsychotic (SGA) medication used in the treatment of a number of mood and ... mental health conditions including schizophrenia and bipolar disorder. ... D2 and serotonergic 5-HT2A activity, resulting in overactivity of central mesolimbic pathways and mesocortical …
Matched Categories: … Adrenergic alpha-Antagonists ... Adrenergic alpha-1 Receptor Antagonists …
Matched Products: … PERILIFE 1 MG FİLM TABLET, 20 ADET ... PERILIFE 2 MG FİLM TABLET, 20 ADET ... PERILIFE 3 MG FİLM TABLET, 20 ADET …
Flunarizine
Flunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. It is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an adjuvant in the therapy of epilepsy.
Approved
Matched Description: … Flunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 ... peripheral origin, and as an adjuvant in the therapy of epilepsy. ... effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and …
Matched Categories: … Calcium-Regulating Hormones and Agents …
Matched Products: … FLUNARIZIN ACIS 5MG ... FLUNARIZIN ACIS 10MG …
Matched Categories: … Calcium-Regulating Hormones and Agents …
Matched Products: … FLUNARIZIN ACIS 5MG ... FLUNARIZIN ACIS 10MG …
Urea
A compound formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids.
Approved
Investigational
Matched Description: … It is the principal end product of protein catabolism and constitutes about one half of the total urinary ... A compound formed in the liver from ammonia produced by the deamination of amino acids. …
Matched Mixtures name: … Hyaluronic Acid Sodium Salt 1% / Tacrolimus 0.1% / Urea 20% ... Lactic Acid 10% / Urea 40% ... Urea 39.5% with 2% Salicylic Acid …
Matched Categories: … Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Emollients and Protectives …
Matched Products: … UREA ACIS 12% CREME ... BETAHA ... ELSPAR %10 KREM, 60 GRAM …
Matched Mixtures name: … Hyaluronic Acid Sodium Salt 1% / Tacrolimus 0.1% / Urea 20% ... Lactic Acid 10% / Urea 40% ... Urea 39.5% with 2% Salicylic Acid …
Matched Categories: … Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Emollients and Protectives …
Matched Products: … UREA ACIS 12% CREME ... BETAHA ... ELSPAR %10 KREM, 60 GRAM …
D-arginine
A D-α-amino acid that is the D-isomer of arginine (only the L-form is physiologically active).
Experimental
Matched Synonyms: … (R)-2-amino-5-guanidinopentanoic acid ... (2R)-2-amino-5-guanidinopentanoic acid ... D-2-Amino-5-guanidinovaleric acid …
Matched Iupac: … (2R)-2-amino-5-carbamimidamidopentanoic acid …
Matched Description: … A D-α-amino acid that is the D-isomer of arginine (only the L-form is physiologically active). …
Matched Iupac: … (2R)-2-amino-5-carbamimidamidopentanoic acid …
Matched Description: … A D-α-amino acid that is the D-isomer of arginine (only the L-form is physiologically active). …
Obeticholic acid
Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury often resulting in end-stage liver failure that requires liver transplantation. Obeticholic acid is a farnesoid-X receptor (FXR) agonist used to treat this condition, possibly allowing for increased survival. In 2016, it was granted approval...
Approved
Matched Synonyms: … 6-alpha-ethylchenodeoxycholic acid ... Obeticholic acid ... 6-ethylchenodeoxycholic acid …
Matched Name: … Obeticholic acid …
Matched Iupac: … 11aR)-5-ethyl-4,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoic acid …
Matched Description: … The NDA from Intercept Pharmaceuticals was approved in November 2019 and obeticholic acid is expected ... obeticholic acid in patients with PBC and advanced cirrhosis (e.g. those with portal hypertension or ... Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury …
Matched Categories: … Bile Acids and Salts ... Bile acids and derivatives ... Alimentary Tract and Metabolism ... Bile and Liver Therapy ... Cholic Acids …
Matched Name: … Obeticholic acid …
Matched Iupac: … 11aR)-5-ethyl-4,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoic acid …
Matched Description: … The NDA from Intercept Pharmaceuticals was approved in November 2019 and obeticholic acid is expected ... obeticholic acid in patients with PBC and advanced cirrhosis (e.g. those with portal hypertension or ... Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury …
Matched Categories: … Bile Acids and Salts ... Bile acids and derivatives ... Alimentary Tract and Metabolism ... Bile and Liver Therapy ... Cholic Acids …
Oridonin
Oridonin is under investigation in clinical trial NCT05130892 (Effect of Inflammasome Inhibitor on Hscrp in Patients After PCI).
Investigational
Matched Synonyms: … Kaur-16-en-15-one, 7.alpha.,20-epoxy-1.alpha.,6.beta.,7,14-tetrahydroxy-, (14r)- ... Kaur-16-en-15-one, 7,20-epoxy-1,6,7,14-tetrahydroxy-, (1.alpha.,6.beta.,7.alpha.,14r)- …
Prephenic acid
Experimental
Matched Synonyms: … cis-1-Carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1-propanoic acid ... (1s,4s)-prephenic acid ... cis-prephenic acid …
Matched Name: … Prephenic acid …
Matched Iupac: … (1s,4s)-1-(2-carboxy-2-oxoethyl)-4-hydroxycyclohexa-2,5-diene-1-carboxylic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Matched Name: … Prephenic acid …
Matched Iupac: … (1s,4s)-1-(2-carboxy-2-oxoethyl)-4-hydroxycyclohexa-2,5-diene-1-carboxylic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Reveglucosidase alfa
Investigational
Matched Synonyms: … alpha-glucosidase (acid maltase, aglucosidase alfa) produced in chinese hamster ovary (cho) cells, glycoform ... Des-(2-7)-human insulin-like growth factor ii fusion protein with glycyl-l-alanyl-l-prolyl-human lysosomal …
Linerixibat
GSK2330672 has been investigated for the treatment of Diabetes Mellitus, Type 2.
Investigational
Matched Synonyms: … PENTANEDIOIC ACID, 3-((((3R,5R)-3-BUTYL-3-ETHYL-2,3,4,5-TETRAHYDRO-7-METHOXY-1,1-DIOXIDO-5-PHENYL-1,4 ... YL)METHYL)AMINO)PENTANEDIOIC ACID ... -BENZOTHIAZEPIN-8-YL)METHYL)AMINO)- …
Matched Iupac: … yl]methyl}amino)pentanedioic acid ... {[(3R,5R)-3-butyl-3-ethyl-7-methoxy-1,1-dioxo-5-phenyl-2,3,4,5-tetrahydro-1lambda6,4-benzothiazepin-8- …
Matched Iupac: … yl]methyl}amino)pentanedioic acid ... {[(3R,5R)-3-butyl-3-ethyl-7-methoxy-1,1-dioxo-5-phenyl-2,3,4,5-tetrahydro-1lambda6,4-benzothiazepin-8- …
Cannabidiolic acid methyl ester
Investigational
Matched Synonyms: … 2-{2,4-dihydroxy-3-[(1R,6R)-3-methyl-6-(prop-1-en-2-yl)cyclohex-2-en-1-yl]-6-pentylphenyl}acetic acid …
Matched Name: … Cannabidiolic acid methyl ester …
Matched Iupac: … 2-{2,4-dihydroxy-3-[(1R,6R)-3-methyl-6-(prop-1-en-2-yl)cyclohex-2-en-1-yl]-6-pentylphenyl}acetic acid …
Matched Name: … Cannabidiolic acid methyl ester …
Matched Iupac: … 2-{2,4-dihydroxy-3-[(1R,6R)-3-methyl-6-(prop-1-en-2-yl)cyclohex-2-en-1-yl]-6-pentylphenyl}acetic acid …
Idroxioleic acid
Investigational
Matched Synonyms: … Alpha-hydroxyoleic acid ... Rac-(2r,9z)-2-hydroxyoctadec-9-enoic acid ... 2-hydroxyoleic acid …
Matched Name: … Idroxioleic acid …
Matched Iupac: … (9Z)-2-hydroxyoctadec-9-enoic acid …
Matched Categories: … Fatty Acids ... Fatty Acids, Unsaturated ... Fatty Acids, Monounsaturated …
Matched Name: … Idroxioleic acid …
Matched Iupac: … (9Z)-2-hydroxyoctadec-9-enoic acid …
Matched Categories: … Fatty Acids ... Fatty Acids, Unsaturated ... Fatty Acids, Monounsaturated …
2-(1-Hexyloxyethyl)-2-devinyl pyropheophorbide-a
2-(1-Hexyloxyethyl)-2-devinyl pyropheophorbide-a is under investigation in clinical trial NCT01668823 (Photodynamic Therapy in Treating Patients With Lung Cancer).
Investigational
Matched Synonyms: … 3-PHORBINEPROPANOIC ACID, 14-ETHYL-9-(1-(HEXYLOXY)ETHYL)-4,8,13,18-TETRAMETHYL-20-OXO-, (3S,4S)- …
Matched Iupac: … ^{10,13}.1^{15,18}.0^{2,6}]hexacosa-1(23),2(6),5(26),8,10(25),11,13,15,17,19-decaen-22-yl]propanoic acid …
Matched Iupac: … ^{10,13}.1^{15,18}.0^{2,6}]hexacosa-1(23),2(6),5(26),8,10(25),11,13,15,17,19-decaen-22-yl]propanoic acid …
Displaying drugs 701 - 725 of 4319 in total