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Displaying drugs 701 - 725 of 2475 in total
Experimental
Matched Synonyms: … 5,7-Dichorokynurenic acid ... 5,7-Dichloroquinurenic acid
Matched Name: … 5,7-Dichlorokynurenic acid
Matched Iupac: … 5,7-dichloro-4-hydroxyquinoline-2-carboxylic acid
Matched Categories: … Acids, Heterocyclic ... Excitatory Amino Acid Agents ... Excitatory Amino Acid Antagonists …
An antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids. It acts by interfering with the enzymatic steps involved in the conversion of acetate to hydroxymethylglutaryl coenzyme A as well as inhibiting the activity of HYDROXYMETHYLGLUTARYL COA REDUCTASES which is the rate limiting enzyme in the biosynthesis of cholesterol.
Experimental
Matched Synonyms: … Dicrotalic acid ... 3-hydroxy-3-methylglutaric acid
Matched Iupac: … 3-hydroxy-3-methylpentanedioic acid
Matched Description: … An antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids
Experimental
Investigational
Matched Synonyms: … arsenous acid ... arsorous acid
Matched Name: … Arsenous acid
Matched Iupac: … arsorous acid
Investigational
Matched Synonyms: … Citric acid ethyl ester ... Citric acid triethyl ester …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Tricarboxylic Acids
Experimental
Matched Synonyms: … Propanimidic acid ... Propionic acid amide …
Sinapic acid is a matrix for matrix-assisted laser desorption technique for protein MW determination. It is also a constituent of propolis.
Experimental
Matched Synonyms: … Sinapinic acid ... trans-sinapic acid ... (E)-3-(4-Hydroxy-3,5-dimethoxyphenyl)-2-propenoic acid
Matched Name: … Sinapic acid
Matched Iupac: … (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoic acid
Matched Description: … Sinapic acid is a matrix for matrix-assisted laser desorption technique for protein MW determination. …
Matched Categories: … Indicators and Reagents ... Carboxylic Acids ... Acids, Carbocyclic …
Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury often resulting in end-stage liver failure that requires liver transplantation. Obeticholic acid is a farnesoid-X receptor (FXR) agonist used to treat this condition, possibly allowing for increased survival. In 2016, it was granted approval...
Approved
Matched Synonyms: … Obeticholic acid ... 6-ethylchenodeoxycholic acid ... 6α-ethylchenodeoxycholic acid
Matched Name: … Obeticholic acid
Matched Iupac: … 11aR)-5-ethyl-4,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoic acid
Matched Description: … The NDA from Intercept Pharmaceuticals was approved in November 2019 and obeticholic acid is expected ... Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury ... in patients with PBC and advanced cirrhosis (e.g. those with portal hypertension or hepatic decompensation …
Matched Categories: … Bile Acids and Salts ... Bile acids and derivatives ... Alimentary Tract and Metabolism ... Bile and Liver Therapy ... Cholic Acids
Experimental
Matched Synonyms: … p-Dimethylamino benzoic acid ... N,N-Dimethyl-4-aminobenzoic acid ... N,N-Dimethyl-p-aminobenzoic acid
Matched Name: … 4-(Dimethylamino)benzoic acid
Matched Iupac: … 4-(dimethylamino)benzoic acid
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids
Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties.
Approved
Vet approved
Matched Synonyms: … 3-Benzoylhydratropic acid ... m-Benzoylhydratropic acid ... 2-(3-Benzoylphenyl)propionic acid
Matched Iupac: … 2-(3-benzoylphenyl)propanoic acid
Matched Description: … and antipyretic properties. ... Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Ketoprofen and isomer ... Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Investigational
Matched Synonyms: … 1h-benzimidazole, 5,6-dibromo-1-(1-methylethyl)-4-nitro-2-(4-piperidinyl)- ... 5,6-dibromo-1-(1-methylethyl)-4-nitro-2-(4-piperidinyl)-1h-benzimidazole ... 5,6-dibromo-4-nitro-2-(piperidin-4-yl)-1-(propan-2-yl)-1h-1,3-benzimidazole …
Matched Iupac: … 5,6-dibromo-4-nitro-2-(piperidin-4-yl)-1-(propan-2-yl)-1H-1,3-benzodiazole …
A mixture of fish oil and primrose oil, doconexent is used as a high-docosahexaenoic acid (DHA) supplement. DHA is a 22 carbon chain with 6 cis double bonds with anti-inflammatory effects. It can be biosythesized from alpha-linolenic acid or commercially manufactured from microalgae. It is an omega-3 fatty acid and...
Approved
Investigational
Matched Synonyms: … cervonic acid ... Docosahexanoic Acid ... Docosahexaenoic acid
Matched Iupac: … (4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoic acid
Matched Description: … A mixture of fish oil and primrose oil, doconexent is used as a high-docosahexaenoic acid (DHA) supplement ... It is an omega-3 fatty acid and primary structural component of the human brain, cerebral cortex, skin ... , and retina thus plays an important role in their development and function. …
Matched Mixtures name: … Iron Polysaccharides Folic Acid DHA …
Matched Categories: … Fatty Acids ... Fatty Acids, Omega-3 ... Fatty Acids, Unsaturated …
Investigational
Matched Synonyms: … 2-hydroxyoleic acid ... Alpha-hydroxyoleic acid ... (z)-2-hydroxyoctadec-9-enoic acid
Matched Name: … Idroxioleic acid
Matched Iupac: … (9Z)-2-hydroxyoctadec-9-enoic acid
Matched Categories: … Fatty Acids ... Fatty Acids, Unsaturated ... Fatty Acids, Monounsaturated …
Experimental
Matched Synonyms: … (dimethylamino)acetic acid ... 2-(Dimethylamino)acetic acid ... N,N-Dimethylaminoacetic acid
Matched Iupac: … 2-(dimethylamino)acetic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids
The glycine amide of 4-aminobenzoic acid. Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory capacity. [PubChem]
Approved
Investigational
Matched Synonyms: … Aminohippuric acid ... 4-aminohippuric acid ... p-aminohippuric acid
Matched Name: … Aminohippuric acid
Matched Iupac: … 2-[(4-aminophenyl)formamido]acetic acid
Matched Description: … Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory ... The glycine amide of 4-aminobenzoic acid. …
Matched Categories: … Benzamides and benzamide derivatives ... Indicators and Reagents ... Tests for Renal Function and Ureteral Injuries ... Keto Acids ... Acids, Carbocyclic …
An oxidation product of tryptophan metabolism. It may be a free radical scavenger and a carcinogen.
Experimental
Matched Synonyms: … 3-Oxyanthranilic acid ... 2-Amino-3-hydroxy-benzoic acid ... 2-Amino-3-Hydroxybenzoic Acid
Matched Name: … 3-hydroxyanthranilic acid
Matched Iupac: … 2-amino-3-hydroxybenzoic acid
Matched Description: … It may be a free radical scavenger and a carcinogen. …
Matched Categories: … Acids, Carbocyclic ... Hydroxy Acids ... Carboxylic Acids
Experimental
Matched Synonyms: … Laurent acid ... 1-Amino-5-naphthalenesufonic acid ... 5-Naphthylamine-1-sulfonic acid
Matched Name: … 1-Naphthylamine-5-sulfonic acid
Matched Iupac: … 5-aminonaphthalene-1-sulfonic acid
Matched Categories: … Sulfur Acids ... Arylsulfonic Acids ... Sulfonic Acids
Delamanid is an anti-tuberculosis agent derived from the nitro-dihydro-imidazooxazole class of compounds that inhibits mycolic acid synthesis of bacterial cell wall . It is used in the treatment of multidrug-resistant and extensively drug-resistant tuberculosis (TB) in a combination regimen. Emergence of multidrug-resistant and extensively drug-resistant tuberculosis creates clinical challenges for...
Approved
Investigational
Matched Synonyms: … (2R)-2-methyl-6-nitro-2-((4-(4-(4-(trifluoromethoxy)phenoxy)piperidin-1-yl)phenoxy)methyl)-2,3-dihydroimidazo ... (R)-2-methyl-6-nitro-2-{4-[4-(4-trifluoromethoxyphenoxy)piperidin-1-yl]phenoxymethyl}-2,3-dihydroimidazo ... Imidazo(2,1-B)oxazole, 2,3-dihydro-2-methyl-6-nitro-2-((4-(4-(4-(trifluoromethoxy)phenoxy)-1-piperidinyl …
Matched Iupac: … 1-(4-{[(2R)-2-methyl-6-nitro-2H,3H-imidazo[2,1-b][1,3]oxazol-2-yl]methoxy}phenyl)-4-[4-(trifluoromethoxy …
Matched Description: … that inhibits mycolic acid synthesis of bacterial cell wall [A31965]. ... Delamanid is an anti-tuberculosis agent derived from the nitro-dihydro-imidazooxazole class of compounds ... response to standardized antituberculosis treatments as [DB00951] and [DB01045]. …
Matched Categories: … Nitro Compounds …
A member of the vitamin B complex. It used to be common in sunscreening agents until found to also be a sensitizer. The potassium salt is used therapeutically in fibrotic skin disorders.
Approved
Experimental
Matched Synonyms: … Aminobenzoic acid ... 4-aminobenzoic acid ... p-Aminobenzoic acid
Matched Name: … Aminobenzoic acid
Matched Iupac: … 4-aminobenzoic acid
Matched Categories: … Emollients and Protectives ... 4-Aminobenzoic Acid ... Acids, Carbocyclic ... Carboxylic Acids ... aminobenzoic acid
An N-acyl derivative of neuraminic acid. N-acetylneuraminic acid occurs in many polysaccharides, glycoproteins, and glycolipids in animals and bacteria. (From Dorland, 28th ed, p1518)
Experimental
Matched Synonyms: … beta-sialic acid ... N-acetyl-β-neuraminic acid ... (-)-N-acetyl-beta-neuraminic acid
Matched Name: … N-acetyl-beta-neuraminic acid
Matched Iupac: … (2S,4S,5R,6R)-5-acetamido-2,4-dihydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid
Matched Description: … N-acetylneuraminic acid occurs in many polysaccharides, glycoproteins, and glycolipids in animals and ... An N-acyl derivative of neuraminic acid. …
Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins. Proline is sometimes called an imino acid, although the IUPAC definition of an imine requires a carbon-nitrogen double bond. Proline is a non-essential amino acid that is synthesized from glutamic acid. It...
Nutraceutical
Matched Synonyms: … (-)-2-Pyrrolidinecarboxylic acid ... 2-Pyrrolidinecarboxylic acid ... (−)-2-pyrrolidinecarboxylic acid
Matched Iupac: … (2S)-pyrrolidine-2-carboxylic acid
Matched Description: … It is an essential component of collagen and is important for proper functioning of joints and tendons ... Proline is a non-essential amino acid that is synthesized from glutamic acid. ... Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins. …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... Travasol Amino Acid Inj 8.5% …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Imino Acids ... Amino Acids, Cyclic ... Proteinogenic Amino Acids
A compound that inhibits aminobutyrate aminotransferase activity in vivo, thereby raising the level of gamma-aminobutyric acid in tissues. [PubChem]
Experimental
Matched Synonyms: … aminoxyacetic acid ... (aminooxy)acetic acid
Matched Name: … Aminooxyacetic acid
Matched Iupac: … 2-(aminooxy)acetic acid
Matched Description: … inhibits aminobutyrate aminotransferase activity in vivo, thereby raising the level of gamma-aminobutyric acid
Matched Categories: … Acids, Acyclic ... Carboxylic Acids
Experimental
Matched Synonyms: … β-D-galacturonic acid ... β-D-Galactopyranuronic acid
Matched Name: … beta-D-Galactopyranuronic acid
Matched Iupac: … (2S,3R,4S,5R,6R)-3,4,5,6-tetrahydroxyoxane-2-carboxylic acid
Experimental
Matched Synonyms: … p-salicylic acid ... p-Hydroxybenzoic acid
Matched Name: … 4-hydroxybenzoic acid
Matched Iupac: … 4-hydroxybenzoic acid
Matched Categories: … Hydroxy Acids ... Acids, Carbocyclic ... Carboxylic Acids
Experimental
Matched Synonyms: … 2,6-Dipicolinic acid ... 2,6-pyridinedicarboxylic acid
Matched Name: … Dipicolinic acid
Matched Iupac: … pyridine-2,6-dicarboxylic acid
Matched Categories: … Acids, Heterocyclic …
Necuparanib is under investigation in clinical trial NCT01621243 (M402 in Combination With Nab-paclitaxel and Gemcitabine in Pancreatic Cancer).
Investigational
Matched Synonyms: … M402 free acid ... M-402 free acid
Matched Description: … Necuparanib is under investigation in clinical trial NCT01621243 (M402 in Combination With Nab-paclitaxel and
Displaying drugs 701 - 725 of 2475 in total