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Displaying drugs 701 - 725 of 1634 in total

Hydromorphone

Hydromorphone is a pure opioid, a semi-synthetic hydrogenated ketone derivative of morphine that has been available clinically since 1920. Structurally, hydromorphone derived from morphine in the modification of the hydroxyl group in the carbon 6 to a carbonyl and the absence of a double bond between the carbon 7 and...
Approved
Illicit
Matched Description: … the absence of a double bond between the carbon 7 and 8. ... Due to these modifications, it presents a very high potency and comparable side effect profile to the ... hydromorphone derived from [morphine] in the modification of the hydroxyl group in the carbon 6 to a carbonyl and …
Matched Categories: … hydromorphone and naloxone ... hydromorphone and antispasmodics …
Matched Products: … Palladone XL - 24mg ... HYDROMORPHON 1A 24MG ... HYDROMORPHON ARI 24MG …

2-(aminomethyl)phenol

2-(aminomethyl)phenol is under investigation in clinical trial NCT03556319 (2-HOBA: Multiple Dosing Study in Older Adults).
Investigational
Matched Name: … 2-(aminomethyl)phenol …
Matched Iupac: … 2-(aminomethyl)phenol …
Matched Description: … 2-(aminomethyl)phenol is under investigation in clinical trial NCT03556319 (2-HOBA: Multiple Dosing Study …

Flavone

Approved
Experimental
Matched Synonyms: … 2-Phenyl-4-chromone ... 2-Phenyl-4-benzopyron ... 2-phenyl-γ-benzopyrone …
Matched Iupac: … 2-phenyl-4H-chromen-4-one …

2-[1-(4-CHLORO-PHENYL)-ETHYL]-4,6-DINITRO-PHENOL

Experimental
Matched Name: … 2-[1-(4-CHLORO-PHENYL)-ETHYL]-4,6-DINITRO-PHENOL …

Tibolone

Tibolone is a synthetic steroid hormone drug, which is mainly non-selective in its binding profile, acting as an agonist primarily at estrogen receptors (ER), with a preference for ER alpha . Tibolone (Livial, Org OD 14), produced by Organon (West Orange, NJ), is a synthetic steroid that possesses estrogenic, androgenic...
Approved
Investigational
Matched Description: … produced by Organon (West Orange, NJ), is a synthetic steroid that possesses estrogenic, androgenic and ... been used in Europe for almost 2 decades, primarily for the prevention of postmenopausal osteoporosis and ... Tibolone is approved in 90 countries to manage menopausal symptoms and in 45 countries to prevent the …
Matched Categories: … Genito Urinary System and Sex Hormones ... Estrogens, Antiestrogens, and Estrogen Agonist-Antagonists ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … MENOREST (Tibolone 2.5mg per tablet) …

Rofecoxib

Rofecoxib is used for the treatment of osteoarthritis, rheumatoid arthritis, acute pain in adults, and primary dysmenorrhea, as well as acute treatment of migraine attacks with or without auras. Rofecoxib is a solid. This compound belongs to the stilbenes. These are organic compounds containing a 1,2-diphenylethylene moiety. Stilbenes (C6-C2-C6 )...
Approved
Investigational
Withdrawn
Matched Synonyms: … 3-phenyl-4-[4-(methylsulfonyl)phenyl]-2(5H)-furanone ... 4-[4-(methylsulfonyl)phenyl]-3-phenyl-2(5H)-furanone …
Matched Iupac: … 4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofuran-2-one …
Matched Description: … The introduction of one or more hydroxyl groups to a phenyl ring lead to stilbenoids. ... doses of 125, 25, and 50 mg is approximately 93%. ... Rofecoxib is used for the treatment of osteoarthritis, rheumatoid arthritis, acute pain in adults, and …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …

Bupropion

Bupropion (also known as the brand name product Wellbutrin®) is a norepinephrine/dopamine-reuptake inhibitor (NDRI) used most commonly for the management of Major Depressive Disorder (MDD), Seasonal Affective Disorder (SAD), and as an aid for smoking cessation. Bupropion exerts its pharmacological effects by weakly inhibiting the enzymes involved in the uptake...
Approved
Matched Description: … This includes the hypothalamus, which is involved in appetite regulation, and the mesolimbic dopamine ... auto-inhibition, which are associated with a reduction in food intake and increased energy expenditure ... commonly for the management of Major Depressive Disorder (MDD), Seasonal Affective Disorder (SAD), and …
Matched Mixtures name: … Naltrexone Hydrochloride and Bupropion Hydrochloride Extended-Release …
Matched Categories: … bupropion and naltrexone ... bupropion and dextromethorphan ... Dopamine And Norepinephrine Reuptake Inhibitors ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … WELLBUTRIN XL (24 HOUR) 150 MG ... WELLBUTRIN XL (24 HOUR) 300 MG …

4-(trifluoromethyl)phenol

Experimental
Matched Name: … 4-(trifluoromethyl)phenol …
Matched Iupac: … 4-(trifluoromethyl)phenol …

Tapentadol

Tapentadol is a centrally-acting synthetic analgesic with a dual mechanism of action. It is a mu-opioid receptor agonist that also inhibits norepinephrine reuptake.[A260721, A36596] Tapentadol was first approved by the FDA on November 20, 2008. The extended-release formulation of tapentadol was also approved by the FDA on August 26, 2011....
Approved
Matched Synonyms: … 3-[(1R,2R)-3-(Dimethylamino)-1-ethyl-2-methylpropyl]phenol ... PHENOL, 3-((1R,2R)-3-(DIMETHYLAMINO)-1-ETHYL-2-METHYLPROPYL)- …
Matched Iupac: … 3-[(2R,3R)-1-(dimethylamino)-2-methylpentan-3-yl]phenol …
Matched Categories: … Phenols …

Trastuzumab

Produced in CHO cell cultures, trastuzumab is a recombinant IgG1 kappa, humanized monoclonal antibody that selectively binds with high affinity in a cell-based assay (Kd = 5 nM) to the extracellular domain of the human epidermal growth factor receptor protein (HER2). It is used as a treatment of human epidermal...
Approved
Investigational
Matched Description: … Trastuzumab binds to HER2 and suppresses cancer cell growth, proliferation, and survival directly and ... that the overexpression or gene amplification of HER2 has been found in about 20–30% of breast cancers and ... While Ogivri is the first biosimilar approved in the U.S. for the treatment of breast cancer or stomach …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... pertuzumab and trastuzumab ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … LYOPHILIZED POWDER FOR INJECTION 440MG PER VIAL ... OGIVRI™ LYOPHILIZED POWDER FOR INJECTION 440MG PER VIAL …

CTS-1027

CTS-1027 has been used in trials studying the treatment of Hepatitis C and Chronic Hepatitis C Virus Infection.
Experimental
Investigational
Matched Synonyms: … 2H-PYRAN-4-CARBOXAMIDE, 4-(((4-(4-CHLOROPHENOXY)PHENYL)SULFONYL)METHYL)TETRAHYDRO-N-HYDROXY- ... 4-(((4-(4-CHLOROPHENOXY)PHENYL)SULFONYL)-METHYL) TETRAHYDRO-N-HYDROXY-2H-PYRAN-4-CARBOXAMIDE ... 4-[[[4-(4-Chlorophenoxy)phenyl]sulfonyl]-methyl] tetrahydro-N-hydroxy-2H-pyran-4-carboxamide …
Matched Description: … CTS-1027 has been used in trials studying the treatment of Hepatitis C and Chronic Hepatitis C Virus …

Phenyl trimethicone

Experimental
Matched Synonyms: … Methyl phenyl polysiloxane …
Matched Name: … Phenyl trimethicone …

Paeonia lactiflora root

Experimental
Matched Synonyms: … White peony root ... Red peony root (paeonia lactiflora) …

3-Phenylpropylamine

Experimental
Matched Synonyms: … 3-phenyl-1-aminopropane ... 3-phenyl-1-propylamine ... 3-phenyl-N-propylamine …

24,25-Dihydroxycholecalciferol

Investigational
Matched Synonyms: … 24-hydroxycalcidiol ... Secalciferol, (24rs)- …
Matched Categories: … Diet, Food, and Nutrition ... Calcium-Regulating Hormones and Agents ... Vitamin D and Analogues …

Arsenic trioxide

Arsenic trioxide is a chemotherapeutic agent of idiopathic function used to treat leukemia that is unresponsive to first line agents. It is suspected that arsenic trisulfide induces cancer cells to undergo apoptosis. In general, arsenic is known to be a naturally toxic substance capable of eliciting a variety of dangerous...
Approved
Investigational
Matched Synonyms: … White arsenic …
Matched Categories: … Antineoplastic and Immunomodulating Agents …

4-Phenylfentanyl

4-Phenylfentanyl is a sythetic opioid derived from fentanyl. 4-Phenylfentanyl is around 8x the potency of fentanyl in analgesic tests on animals, but more complex 4-heteroaryl derivatives such as substituted thiophenes and thiazoles are more potent still, as they are closer bioisosteres to the 4-carbomethoxy group of carfentanil.
Illicit
Matched Synonyms: … N-(1-Phenethyl-4-phenyl-4-piperidyl)-N-phenyl-propanamide …
Matched Iupac: … N-phenyl-N-[4-phenyl-1-(2-phenylethyl)piperidin-4-yl]propanamide …
Matched Description: … analgesic tests on animals, but more complex 4-heteroaryl derivatives such as substituted thiophenes and …

Profadol

Investigational
Matched Synonyms: … M-(1-methyl-3-propyl-3-pyrrolidinyl)phenol ... Phenol, 3-(1-methyl-3-propyl-3-pyrrolidinyl)- ... Phenol, m-(1-methyl-3-propyl-3-pyrrolidinyl)- …
Matched Iupac: … 3-(1-methyl-3-propylpyrrolidin-3-yl)phenol …

Fluoxetine

Fluoxetine is a 2nd generation antidepressant categorized as a selective serotonin reuptake inhibitor (SSRI). It gained FDA approval in 1987 and although it was initially intended for the treatment of depression, today it is commonly prescribed to manage depression in addition to various other pathologies.
Approved
Vet approved
Matched Synonyms: … (+-)-N-Methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine ... (+-)-N-Methyl-3-phenyl-3-((alpha,alpha,alpha-trifluoro-P-tolyl)oxy)propylamine …
Matched Iupac: … methyl({3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl})amine …
Matched Description: … [A181673] It gained FDA approval in 1987 and although it was initially intended for the treatment of …
Matched Mixtures name: … Olanzapine and Fluoxetine ... Olanzapine and Fluoxetine ... Olanzapine and Fluoxetine …
Matched Categories: … fluoxetine and psycholeptics ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … ANDEP ... PROZAC 20 MG KAPSUL, 24 ADET ... DEPREKS 20 MG KAPSUL, 24 ADET …

Phenyl salicylate

Phenyl salicylate is a 2-hydroxybenzoic acid phenyl ester. It is utilized in some manufacturing processes of polymers, lacquers, adhesives, waxes, as well as polishes. It is an active ingredient in some pharmaceutical products as a mild analgesic for pain relief by releasing salicylate (found in DB00945 ). Phenyl salicylate may...
Approved
Matched Name: … Phenyl salicylate …
Matched Iupac: … phenyl 2-hydroxybenzoate …
Matched Description: … This compound belongs to the class of organic compounds known as depsides and depsidones. ... Phenyl salicylate is a 2-hydroxybenzoic acid phenyl ester. ... Phenyl salicylate is used as a food additive in the USA [L2479]. …
Matched Categories: … Genito Urinary System and Sex Hormones ... Miscellaneous Analgesics and Antipyretics ... Phenols ... phenyl salicylate …

Nitroglycerin

Nitroglycerin, also known as glyceryl trinitrate, is an organic nitrate and a vasodilating agent that was first discovered in 1847. Originally used to dynamite, its antianginal effects were identified in the late 1860s after it produced headaches in factory workers while workers with angina pectoris or heart failure experienced relief...
Approved
Investigational
Matched Description: … [A180166,A180172] Its use as a treatment for angina dates back to 1879 and is still used to treat and ... Nitroglycerin, also known as glyceryl trinitrate,[A180169] is an organic nitrate and a vasodilating agent ... [A249970] Nitroglycerin causes vasodilation in both arteries and veins. …
Matched Categories: … Nitrates and Nitrites ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … NITRODERM TTS 5 (5MG/24HR) ... NITRODERM TTS 10 (10MG/24HR) ... Nitroderm TTS 5 mg/24 h Depot - Pflaster …

Propofol

Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. drowsiness,...
Approved
Investigational
Vet approved
Matched Synonyms: … 2,6-bis(1-methylethyl)phenol …
Matched Iupac: … 2,6-bis(propan-2-yl)phenol …
Matched Description: … IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained ... for induction and/or maintenance of anaesthesia prior to and during surgeries. ... Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia …
Matched Categories: … Hypnotics and Sedatives ... Phenols …

p-Cumylphenol

Experimental
Matched Synonyms: … 4-(alpha,alpha-Dimethylbenzyl)phenol …
Matched Iupac: … 4-(2-phenylpropan-2-yl)phenol …

N-phenylthiourea

Experimental
Matched Synonyms: … 1-phenyl-2-thiourea ... phenyl-2-thiourea …

N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine

N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine is a component of black rubber. It is also a dermatological sensitizer and allergen. Sensitivity to N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine may be identified with a clinical patch test.
Approved
Matched Synonyms: … N-Cyclohexyl-N'-phenyl-p-phenylendiamine ... N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine ... N-cyclohexyl-N'-phenyl-p-phenylenediamine …
Matched Name: … N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine …
Matched Description: … It is also a dermatological sensitizer and allergen. ... N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine is a component of black rubber. ... Sensitivity to N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine may be identified with a clinical patch test …
Displaying drugs 701 - 725 of 1634 in total