Displaying drugs 701 - 725 of 2592 in total
Aztreonam
A monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum. It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges, bladder, and kidneys. It may cause a superinfection with gram-positive organisms.
Approved
Matched Synonyms: … )oxy)-2-methylpropionic acid ... (Z,)-2-((((2-Amino-4-thiazolyl)(((2S,3S,)-2-methyl-4-oxo-1-sulfo-3-azetidinyl)carbamoyl)methylene)amino ... {[(2S,3S)-2-methyl-4-oxo-1-sulfoazetidin-3-yl]amino} -2- oxoethylidene]amino}oxy)-2-methylpropanoic acid …
Matched Description: … , bladder, and kidneys. ... It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges …
Matched Categories: … Sulfur Compounds …
Matched Description: … , bladder, and kidneys. ... It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges …
Matched Categories: … Sulfur Compounds …
Chlorothiazide
A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p812)
Approved
Vet approved
Matched Synonyms: … 6-Chloro-1,1-dioxo-1,2-dihydro-1lambda*6*-benzo[1,2,4]thiadiazine-7-sulfonic acid amide …
Matched Description: … A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. …
Matched Categories: … Sulfur Compounds ... chlorothiazide and potassium ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Description: … A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. …
Matched Categories: … Sulfur Compounds ... chlorothiazide and potassium ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
cis-tetracosenoyl sulfatide
Experimental
Matched Synonyms: … 1-(3-O-sulfo-beta-D-galactosyl)-N-[(15Z)-tetracos-15-enoyl]sphingosine …
Matched Iupac: … hydroxy-2-[(15Z)-tetracos-15-enamido]octadec-4-en-1-yl]oxy}-6-(hydroxymethyl)oxan-4-yl]oxidanesulfonic acid …
Matched Iupac: … hydroxy-2-[(15Z)-tetracos-15-enamido]octadec-4-en-1-yl]oxy}-6-(hydroxymethyl)oxan-4-yl]oxidanesulfonic acid …
Navitoclax
Navitoclax has been used in trials studying the treatment and basic science of Solid Tumors, Non-Hodgkin's Lymphoma, EGFR Activating Mutation, Chronic Lymphoid Leukemia, and Hematological Malignancies, among others.
Navitoclax is an orally bioavailable small molecule inhibitor of Bcl-2 family proteins. It is a substance being studied in the treatment of...
Investigational
Matched Synonyms: … Phenylsulfanylmethyl-Propylamino)-N-(4-{4-[2-(4-Chlorophenyl)-5,5-Dimethylcyclohex-1-Enylmethyl]-Piperazin-1-Yl}-Benzoyl …
Matched Description: … It is a substance being studied in the treatment of lymphomas and other types of cancer. ... Navitoclax has been used in trials studying the treatment and basic science of Solid Tumors, Non-Hodgkin's ... Lymphoma, EGFR Activating Mutation, Chronic Lymphoid Leukemia, and Hematological Malignancies, among …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Sulfur Compounds …
Matched Description: … It is a substance being studied in the treatment of lymphomas and other types of cancer. ... Navitoclax has been used in trials studying the treatment and basic science of Solid Tumors, Non-Hodgkin's ... Lymphoma, EGFR Activating Mutation, Chronic Lymphoid Leukemia, and Hematological Malignancies, among …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Sulfur Compounds …
Mesoxalic acid
Experimental
Matched Synonyms: … Oxomalonic acid ... Ketomalonic acid ... alpha-Ketomalonic acid …
Matched Name: … Mesoxalic acid …
Matched Iupac: … 2-oxopropanedioic acid …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids …
Matched Name: … Mesoxalic acid …
Matched Iupac: … 2-oxopropanedioic acid …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids …
Zileuton
Leukotrienes are substances that induce numerous biological effects including augmentation of neutrophil and eosinophil migration, neutrophil and monocyte aggregation, leukocyte adhesion, increased capillary permeability, and smooth muscle contraction. These effects contribute to inflammation, edema, mucus secretion, and bronchoconstriction in the airways of asthmatic patients. Zileuton relieves such symptoms through its...
Approved
Investigational
Withdrawn
Matched Synonyms: … N-(1-Benzo(b)thien-2-ylethyl)-N-hydroxyurea ... (±)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea ... N-[1-(benzo[b]thiophen-2-yl)ethyl]-N-hydroxyurea …
Matched Description: … inhibition of 5-lipoxygenase, the enzyme that catalyzes the formation of leukotrienes from arachidonic acid ... , and smooth muscle contraction. ... Specifically, it inhibits leukotriene LTB4, LTC4, LTD4, and LTE4 formation. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … inhibition of 5-lipoxygenase, the enzyme that catalyzes the formation of leukotrienes from arachidonic acid ... , and smooth muscle contraction. ... Specifically, it inhibits leukotriene LTB4, LTC4, LTD4, and LTE4 formation. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Phenolsulfonic acid
Experimental
Matched Synonyms: … Sulfocarbolic acid ... Phenolsulfonic acid ... p-Phenolsulfonic acid …
Matched Name: … Phenolsulfonic acid …
Matched Iupac: … 4-hydroxybenzene-1-sulfonic acid …
Matched Name: … Phenolsulfonic acid …
Matched Iupac: … 4-hydroxybenzene-1-sulfonic acid …
Ketotifen
Ketotifen is a benzocycloheptathiophene derivative with potent antihistaminic and mast cell stabilizing properties. It has a similar structure to some other first-generation antihistamines such as cyproheptadine and azatadine. Ketotifen was first developed in Switzerland in 1970 by Sandoz Pharmaceuticals and was initially marketed for the treatment of anaphylaxis. In the...
Approved
Matched Description: … allergic symptoms and disorders,[A231204] including urticaria, mastocytosis, and food allergy. ... Ketotifen is a benzocycloheptathiophene derivative[A231204] with potent antihistaminic and mast cell ... It has a similar structure to some other first-generation antihistamines such as [cyproheptadine] and …
Matched Categories: … Decongestants and Antiallergics ... Sulfur Compounds …
Matched Products: … Up and Up Eye Itch Relief …
Matched Categories: … Decongestants and Antiallergics ... Sulfur Compounds …
Matched Products: … Up and Up Eye Itch Relief …
ADH-503
Investigational
Matched Synonyms: … 2-Hydroxy-N,N,N-trimethylethanaminium (Z)-4-(5-((3-benzyl-4-oxo-2-thioxothiazolidin-5-ylidene)methyl) …
p-Coumaric acid
Experimental
Matched Synonyms: … 4-coumaric acid ... p-Coumaric acid ... (E)-p-coumaric acid …
Matched Name: … p-Coumaric acid …
Matched Iupac: … (2E)-3-(4-hydroxyphenyl)prop-2-enoic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Matched Name: … p-Coumaric acid …
Matched Iupac: … (2E)-3-(4-hydroxyphenyl)prop-2-enoic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Vinylsulfonic acid
Experimental
Matched Synonyms: … Vinylsulphonic acid ... Ethylenesulfonic acid …
Matched Name: … Vinylsulfonic acid …
Matched Iupac: … ethenesulfonic acid …
Matched Categories: … Sulfur Acids ... Sulfur Compounds ... Acids ... Acids, Noncarboxylic …
Matched Name: … Vinylsulfonic acid …
Matched Iupac: … ethenesulfonic acid …
Matched Categories: … Sulfur Acids ... Sulfur Compounds ... Acids ... Acids, Noncarboxylic …
Oxogluric acid
Oxogluric acid (α-Ketoglutarate) is not approved for any indication in the world but is an investigational drug in the United States. In the United States a phase I clinical trial is investigating whether oxogluric acid precursors found in nutritional supplements can benefit patients with the metabolic disorder propionic acidemia. Oxogluric...
Experimental
Investigational
Nutraceutical
Matched Synonyms: … 2-Ketoglutaric acid ... 2-oxoglutaric acid ... Ketoglutaric acid …
Matched Name: … Oxogluric acid …
Matched Iupac: … 2-oxopentanedioic acid …
Matched Description: … reactions during the metabolism of amino acids, forms glutamic acid by combining with ammonia, and reduces ... remove excess ammonia, but it is not officially approved for this indication and only experimental studies ... have shown a reduction in ammonia by oxogluric acid in hemodialysis patients. …
Matched Categories: … Keto Acids ... Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids ... Ketoglutaric Acids …
Matched Name: … Oxogluric acid …
Matched Iupac: … 2-oxopentanedioic acid …
Matched Description: … reactions during the metabolism of amino acids, forms glutamic acid by combining with ammonia, and reduces ... remove excess ammonia, but it is not officially approved for this indication and only experimental studies ... have shown a reduction in ammonia by oxogluric acid in hemodialysis patients. …
Matched Categories: … Keto Acids ... Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids ... Ketoglutaric Acids …
2,2-Dimethylbutyrate
Investigational
Matched Synonyms: … Dimebutic acid ... 2,2-dimethylbutanoic acid ... 2,2-dimethylbutyric acid …
Matched Iupac: … 2,2-dimethylbutanoic acid …
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids, Volatile …
Matched Iupac: … 2,2-dimethylbutanoic acid …
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids, Volatile …
(R)-Mandelic acid
Experimental
Matched Synonyms: … (−)-mandelic acid ... (−)-(R)-mandelic acid ... D-mandelic acid …
Matched Name: … (R)-Mandelic acid …
Matched Iupac: … (2R)-2-hydroxy-2-phenylacetic acid …
Matched Name: … (R)-Mandelic acid …
Matched Iupac: … (2R)-2-hydroxy-2-phenylacetic acid …
CL-315555
CL-315555 is the C isomer of Verteporfin.
Approved
Matched Synonyms: … 23h,25h-benzo(b)porphine-9,13-dipropanoic acid, 18-ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19 …
Matched Iupac: … ^{8,11}.1^{13,16}.0^{19,24}]octacosa-1,3,5,7,9,11(27),12,14,16,18(25),19,21-dodecaen-9-yl]propanoic acid …
Matched Iupac: … ^{8,11}.1^{13,16}.0^{19,24}]octacosa-1,3,5,7,9,11(27),12,14,16,18(25),19,21-dodecaen-9-yl]propanoic acid …
Citraconic acid
Citraconic acid is one of the isomeric dicarboxylic acids produced by the distillation of citric acid, or as metabolites by microorganisms, cis-CH3-C(CO2H)=CHCO2H; the trans-isomer is mesaconic acid.
Experimental
Matched Synonyms: … 2-methylmaleic acid ... Methylmaleic acid ... α-methylmaleic acid …
Matched Name: … Citraconic acid …
Matched Iupac: … (2Z)-2-methylbut-2-enedioic acid …
Matched Description: … Citraconic acid is one of the isomeric dicarboxylic acids produced by the distillation of citric acid ... , or as metabolites by microorganisms, cis-CH3-C(CO2H)=CHCO2H; the trans-isomer is mesaconic acid. …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids …
Matched Name: … Citraconic acid …
Matched Iupac: … (2Z)-2-methylbut-2-enedioic acid …
Matched Description: … Citraconic acid is one of the isomeric dicarboxylic acids produced by the distillation of citric acid ... , or as metabolites by microorganisms, cis-CH3-C(CO2H)=CHCO2H; the trans-isomer is mesaconic acid. …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids …
Trimesic acid
Experimental
Matched Synonyms: … Trimesinic acid ... Trimesitinic acid ... 5-carboxyisophthalic acid …
Matched Name: … Trimesic acid …
Matched Iupac: … benzene-1,3,5-tricarboxylic acid …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
Matched Name: … Trimesic acid …
Matched Iupac: … benzene-1,3,5-tricarboxylic acid …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
Dehydrocholic acid
Dehydrocholic acid is a synthetic bile acid that was prepared from the oxidation of cholic acid with chromic acid . It has been used for stimulation of biliary lipid secretion. The use of dehydrocholic acid in over-the-counter products has been discontinued by Health Canada.
Approved
Investigational
Matched Synonyms: … Dehydrocholic acid ... 3,7,12-triketocholanic acid ... 3,7,12-trioxocholanic acid …
Matched Name: … Dehydrocholic acid …
Matched Iupac: … 9aS,9bS,11aR)-9a,11a-dimethyl-4,7,11-trioxo-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoic acid …
Matched Description: … Dehydrocholic acid is a synthetic bile acid that was prepared from the oxidation of cholic acid with ... chromic acid [A33022]. ... The use of dehydrocholic acid in over-the-counter products has been discontinued by Health Canada. …
Matched Categories: … Bile Acids and Salts ... Cholagogues and Choleretics ... Cholic Acids …
Matched Name: … Dehydrocholic acid …
Matched Iupac: … 9aS,9bS,11aR)-9a,11a-dimethyl-4,7,11-trioxo-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoic acid …
Matched Description: … Dehydrocholic acid is a synthetic bile acid that was prepared from the oxidation of cholic acid with ... chromic acid [A33022]. ... The use of dehydrocholic acid in over-the-counter products has been discontinued by Health Canada. …
Matched Categories: … Bile Acids and Salts ... Cholagogues and Choleretics ... Cholic Acids …
Foscarnet
An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpes viruses and HIV.
Approved
Matched Synonyms: … Carboxyphosphonic acid ... Phosphonoformic acid ... Phosphonomethanoic acid …
Matched Iupac: … phosphonoformic acid …
Matched Description: … Foscarnet also shows activity against human herpes viruses and HIV. …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Phosphonic Acid Derivatives ... Nucleic Acid Synthesis Inhibitors …
Matched Iupac: … phosphonoformic acid …
Matched Description: … Foscarnet also shows activity against human herpes viruses and HIV. …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Phosphonic Acid Derivatives ... Nucleic Acid Synthesis Inhibitors …
D-Lactic acid
A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
Experimental
Matched Synonyms: … (−)-lactic acid ... (R)-lactic acid ... (R)-(−)-lactic acid …
Matched Name: … D-Lactic acid …
Matched Iupac: … (2R)-2-hydroxypropanoic acid …
Matched Categories: … Hydroxy Acids ... Carboxylic Acids …
Matched Name: … D-Lactic acid …
Matched Iupac: … (2R)-2-hydroxypropanoic acid …
Matched Categories: … Hydroxy Acids ... Carboxylic Acids …
Phenylpyruvic acid
Experimental
Matched Synonyms: … 3-phenylpyruvic acid ... Phenylpyruvic acid ... β-phenylpyruvic acid …
Matched Name: … Phenylpyruvic acid …
Matched Iupac: … 2-oxo-3-phenylpropanoic acid …
Matched Categories: … Keto Acids ... Carboxylic Acids ... Acids, Carbocyclic …
Matched Name: … Phenylpyruvic acid …
Matched Iupac: … 2-oxo-3-phenylpropanoic acid …
Matched Categories: … Keto Acids ... Carboxylic Acids ... Acids, Carbocyclic …
3',3-diselenodipropionic acid
Investigational
Matched Synonyms: … Diselenodipropionic acid ... 3',3-diseleno dipropionic acid ... Diseleno-3,3'-dipropionic acid …
Matched Name: … 3',3-diselenodipropionic acid …
Matched Iupac: … 3-[(2-carboxyethyl)diselanyl]propanoic acid …
Matched Name: … 3',3-diselenodipropionic acid …
Matched Iupac: … 3-[(2-carboxyethyl)diselanyl]propanoic acid …
N-[3-(aminomethyl)benzyl]acetamidine
Experimental
Matched Name: … N-[3-(aminomethyl)benzyl]acetamidine …
N-Benzyl-4-Sulfamoyl-Benzamide
Experimental
Matched Name: … N-Benzyl-4-Sulfamoyl-Benzamide …
Matched Iupac: … N-benzyl-4-sulfamoylbenzamide …
Matched Iupac: … N-benzyl-4-sulfamoylbenzamide …
Myristic acid
Experimental
Matched Synonyms: … Tetradecanoic acid ... N-tetradecanoic acid ... N-tetradecan-1-oic acid …
Matched Name: … Myristic acid …
Matched Iupac: … tetradecanoic acid …
Matched Categories: … Fatty Acids ... Myristic Acids …
Matched Name: … Myristic acid …
Matched Iupac: … tetradecanoic acid …
Matched Categories: … Fatty Acids ... Myristic Acids …
Displaying drugs 701 - 725 of 2592 in total